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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</Lang (zh-CN) /MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 81.5510025 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>] TJ ET EMC /P <</MCID 1 >> BDC BT /FAAABG 22 Tf 1 0 0 -1 131.227005 23.67700005 Tm 0 Tr [(TRAF3I)1(P)-1(2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 223.30900574 23.67700005 Tm 2 Tr [<0005>-4<0006>-4<0007>-4<0004>-4<0008>] TJ ET EMC /P <</MCID 3 >> BDC BT /FAAABG 22 Tf 1 0 0 -1 333.74899292 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 4 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 76.125 12.82499981 Tm [(TRAF3IP2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 119.18099976 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 171.68099976 12.82499981 Tm [(   )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 187.43099976 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(TRA)1(F)-1(3IP)1(2)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 124.16500092 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 126.53900146 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 152.18899536 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 154.56300354 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 198.12199402 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 200.4960022 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 238.29200745 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ACT1;)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 87.92199707 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 90.29599762 12.82499981 Tm [(CIKS;)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 111.6289978 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 114.00299835 12.82499981 Tm [(C6orf2;)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 145.45700073 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 147.83099365 12.82499981 Tm [(C6orf4;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 179.28500366 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 181.65899658 12.82499981 Tm [(C6orf5;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 213.11300659 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 215.48699951 12.82499981 Tm [(C6orf6;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 246.94099426 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 249.31500244 12.82499981 Tm [(PSORS)-1(1)1(3)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 287.68499756 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0010000D>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TRAF3IP2)] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 103.43099976 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0012000D>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001300140015>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<00160017>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0018>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0019000D>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 59 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B001C000F000D>] TJ ET EMC /P <</MCID 60 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 61 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001D0004>] TJ ET EMC /P <</MCID 62 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 64 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E001F00200021>] TJ ET EMC /P <</MCID 65 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 68 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002200230024000D>] TJ ET EMC /P <</MCID 69 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 73 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<00060007001C0025000D>] TJ ET EMC /P <</MCID 74 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 79 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 80 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 81 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 82 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 163.2250061 0.75 l 163.2250061 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 164.2250061 -0.25 l 164.2250061 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 83 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 84 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 163.9750061 0.75 m 422.42501831 0.75 l 422.42501831 172.3500061 l 163.9750061 172.3500061 l h f* Q q 1 0 0 1 163.6000061 0 cm -0.625 -0.25 m 259.82501221 -0.25 l 259.82501221 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 85 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 128.977005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 133.477005 11.72200012 Tm [(involved)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 169.84599304 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 174.34599304 11.72200012 Tm [(in)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 182.28700256 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 186.78700256 11.72200012 Tm [(regulat)1(i)-1(ng)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 231.05299377 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 235.55299377 11.72200012 Tm [(res)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(po)1(n)-1(ses)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 30.45400047 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 34.95399857 27.3220005 Tm [(to)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 44.02899933 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 48.52899933 27.3220005 Tm [(cy)-1(t)1(oki)-1(nes)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 88.9940033 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 93.4940033 27.3220005 Tm [(by)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 104.0059967 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 108.5059967 27.3220005 Tm [(members)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 148.93600464 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 153.43600464 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 162.27799988 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 166.77799988 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 180.77900696 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 185.27900696 27.3220005 Tm [(Rel/)-1(NF-)1(k)-1(ap)1(paB)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 250.48500061 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(tr)1(ansc)-1(rip)1(tion)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 54.58399963 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 59.08399963 42.92200089 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 84.20300293 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 88.70300293 42.92200089 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 116.9509964 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 121.4509964 42.92200089 Tm [(These)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 146.53100586 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 151.03100586 42.92200089 Tm [(fa)1(c)-1(t)1(ors)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 180.31599426 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 184.81599426 42.92200089 Tm [(play)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 202.69700623 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 207.19700623 42.92200089 Tm [(a)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 212.17199707 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 216.67199707 42.92200089 Tm [(ce)-1(ntr)1(al)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 245.99699402 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(role)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 16.65999985 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 21.15999985 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 29.10099983 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 33.60100174 58.52199936 Tm [(inn)-1(a)1(te)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 60.52199936 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 65.02200317 58.52199936 Tm [(immun)-1(it)1(y)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 105.88700104 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 110.38700104 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 118.32800293 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 122.82800293 58.52199936 Tm [(response)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 161.82499695 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 166.32499695 58.52199936 Tm [(to)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 175.3999939 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 179.8999939 58.52199936 Tm [(pa)1(tho)1(gen)-1(s,)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 227.98100281 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 232.48100281 58.52199936 Tm [(infla)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(mmat)1(ory)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 39.11600113 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 43.61600113 74.12200165 Tm [(signals)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 73.01499939 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 77.51499939 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 93.79199982 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 98.29199982 74.12200165 Tm [(st)1(re)-1(ss)1(.)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 124.85299683 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 129.35299683 74.12200165 Tm [(This)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 146.61500549 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 151.11500549 74.12200165 Tm [(gene)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 172.6309967 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 177.1309967 74.12200165 Tm [(pro)1(duc)-1(t)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 211.20599365 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 215.70599365 74.12200165 Tm [(interact)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(s)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 4.16599989 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 8.66600037 89.72200012 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 27.06200027 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 31.56200027 89.72200012 Tm [(TRAF)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 53.70999908 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 58.20999908 89.72200012 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 93.68299866 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 98.18299866 89.72200012 Tm [(\(tumor)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 127.67900085 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 132.17900085 89.72200012 Tm [(ne)-1(crosis)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 167.22999573 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 171.72999573 89.72200012 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 196.84899902 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 201.34899902 89.72200012 Tm [(rec)-1(ept)1(or-)1(as)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(sociated)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 35.98699951 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 40.48699951 105.3219986 Tm [(fa)1(c)-1(t)1(ors\))] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 72.77799988 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 77.27799988 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 93.55500031 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 98.05500031 105.3219986 Tm [(either)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 122.9940033 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 127.4940033 105.3219986 Tm [(I-kap)1(paB)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 166.0249939 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 170.5249939 105.3219986 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 197.61300659 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 202.11300659 105.3219986 Tm [(or)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 211.27099609 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 215.77099609 105.3219986 Tm [(MAP)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 236.40299988 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 240.90299988 105.3219986 Tm [(ki)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(nase)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 19.79299927 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 24.29299927 120.92199707 Tm [(to)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 33.36800003 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 37.86800003 120.92199707 Tm [(activat)1(e)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 71.26200104 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 75.76200104 120.92199707 Tm [(either)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 100.7009964 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 105.2009964 120.92199707 Tm [(NF-kapp)1(aB)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 153.18499756 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 157.68499756 120.92199707 Tm [(or)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 166.84300232 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 171.34300232 120.92199707 Tm [(Jun)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 185.99899292 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 190.49899292 120.92199707 Tm [(ki)-1(na)1(se)-1(.)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 219.75300598 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 224.25300598 120.92199707 Tm [(Se)-1(v)1(e)-1(r)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(al)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 7.36999989 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 11.86999989 136.52200317 Tm [(alt)1(e)-1(rnat)1(ive)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 57.23500061 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 61.73500061 136.52200317 Tm [(tr)1(ansc)-1(rip)1(ts)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 106.82299805 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 111.32299805 136.52200317 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 151.66499329 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 156.16499329 136.52200317 Tm [(dif)1(fe)-1(r)1(e)-1(nt)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 193.10499573 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 197.60499573 136.52200317 Tm [(isof)1(orms)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 234.76499939 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 239.26499939 136.52200317 Tm [(ha)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(ve)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 9.83100033 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 14.33100033 152.12199402 Tm [(been)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 35.83800125 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 40.33800125 152.12199402 Tm [(identified.)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 83.43499756 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 87.93499756 152.12199402 Tm [(Anot)1(her)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 122.97299957 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 127.47299957 152.12199402 Tm [(tr)1(ansc)-1(rip)1(t,)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 170.56100464 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 175.06100464 152.12199402 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 200.15800476 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 204.65800476 152.12199402 Tm [(do)1(e)-1(s)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 225.40899658 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 229.90899658 152.12199402 Tm [(not)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 244.52999878 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(en)-1(cod)1(e)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 31.75 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 36.25 167.72200012 Tm [(a)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 41.22499847 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 45.72499847 167.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 77.03199768 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 81.53199768 167.72200012 Tm [(and)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 97.80899811 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 102.30899811 167.72200012 Tm [(is)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 108.87000275 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 113.37000275 167.72200012 Tm [(tr)1(ansc)-1(rib)1(e)-1(d)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 161.80200195 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 166.30200195 167.72200012 Tm [(in)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 174.24299622 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 178.74299622 167.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 192.7440033 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 197.2440033 167.72200012 Tm [(op)1(posit)1(e)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 235.20399475 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 239.70399475 167.72200012 Tm [(ori)] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 163.6000061 0.75 m 163.6000061 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.80001831 0.75 m 422.80001831 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17501831 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 172.7250061 m 423.17501831 172.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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