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/FAAABB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 76.125 12.82499981 Tm [(TOB1\(Pho)-1(sph)-1(o-S)-1(e)1(r16)1(4\))] TJ ET EMC /P <</MCID 8 >> BDC BT 1 0 0 -1 175.63900757 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 180.88900757 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 233.38900757 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 238.63900757 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 12 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 13 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(TOB1\(Phosp)-1(ho)-1(-Ser)1(164\))] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 183.2480011 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 185.62199402 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 211.27200317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 213.64599609 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 257.20498657 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 259.57901001 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 297.375 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 24 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 25 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TOB;)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 83.58999634 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 85.96399689 12.82499981 Tm [(TROB;)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 112.25499725 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 114.6289978 12.82499981 Tm [(AP)1(RO6;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 146.91299438 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 149.28700256 12.82499981 Tm [(PIG)1(49;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 177.43400574 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 179.80799866 12.82499981 Tm [(TROB1)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 208.61099243 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 41 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <</MCID 42 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0015000D>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<001B001C>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001D>] TJ ET EMC /P <</MCID 52 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001E000D>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001F000D>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TOB1\(Pho)-1(sph)-1(o-S)-1(e)1(r16)1(4\))] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 162.51400757 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 64 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0020002100220023000D>] TJ ET EMC /P <</MCID 65 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 96.36599731 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 125.72799683 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 128.102005 12.82499981 Tm [(Rat)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 142.3500061 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 72 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002400250026000D>] TJ ET EMC /P <</MCID 73 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 77 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700120027000D>] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 81 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 82 >> BDC BT /FAAABI 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 83 >> BDC BT /FAAACC 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 84 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 163.9750061 0.75 l 163.9750061 109.94999695 l 0.375 109.94999695 l h f* Q q -0.625 -0.25 m 164.9750061 -0.25 l 164.9750061 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 85 >> BDC BT /FAAACC 9 Tf 1 0 0 -1 0 58.52199936 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 86 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 57.29199982 58.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 164.7250061 0.75 m 422.375 0.75 l 422.375 109.94999695 l 164.7250061 109.94999695 l h f* Q q 1 0 0 1 164.3500061 0 cm -0.625 -0.25 m 259.0249939 -0.25 l 259.0249939 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 87 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(tr)1(ansduc)-1(er)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 216.11199951 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 220.61199951 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 229.45399475 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 233.95399475 11.72200012 Tm [(erb)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(B-2)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 14.81799984 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 19.31800079 27.3220005 Tm [(/B)-1(-)1(c)-1(ell)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 47.11299896 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 51.61299896 27.3220005 Tm [(tr)1(ansloc)-1(a)1(tion)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 107.70899963 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 112.20899963 27.3220005 Tm [(gene)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 133.7250061 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 138.2250061 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 169.53199768 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 174.03199768 27.3220005 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 202.27999878 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 206.77999878 27.3220005 Tm [(Membe)-1(r)1(s)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 247.57000732 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 8.84200001 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 13.34200001 42.92200089 Tm [(th)1(is)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 28.79800034 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 33.29800034 42.92200089 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 59.38000107 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 63.88000107 42.92200089 Tm [(are)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 77.39800262 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 81.89800262 42.92200089 Tm [(anti-)1(pro)1(l)-1(if)1(e)-1(ra)1(tive)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 153.9730072 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 158.4730072 42.92200089 Tm [(fa)1(c)-1(t)1(ors)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 187.75799561 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 192.25799561 42.92200089 Tm [(th)1(at)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 209.47999573 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 213.97999573 42.92200089 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 234.32699585 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 238.82699585 42.92200089 Tm [(th)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(e)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 5.10599995 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 9.60599995 58.52199936 Tm [(po)1(ten)-1(t)1(ial)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 48.19900131 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 52.69900131 58.52199936 Tm [(to)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 61.77399826 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 66.27400208 58.52199936 Tm [(regulat)1(e)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 101.9489975 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 106.4489975 58.52199936 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 120.85900116 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 125.35900116 58.52199936 Tm [(gr)1(owt)1(h.)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 158.44099426 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 162.94099426 58.52199936 Tm [(The)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 178.7480011 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 183.2480011 58.52199936 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 220.75500488 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 225.25500488 58.52199936 Tm [(pro)1(te)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(in)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 7.94099998 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 12.44099998 74.12200165 Tm [(may)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 30.61199951 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 35.11199951 74.12200165 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 70.85299683 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 75.35299683 74.12200165 Tm [(as)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 84.4940033 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 88.9940033 74.12200165 Tm [(a)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 93.96900177 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 98.46900177 74.12200165 Tm [(tumor)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 124.95899963 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 129.45899963 74.12200165 Tm [(supp)1(re)-1(ss)1(or.)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 178.86700439 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 183.36700439 74.12200165 Tm [(Alt)1(e)-1(rna)1(te)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 222.97099304 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 227.47099304 74.12200165 Tm [(splici)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ng)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 11.30300045 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 15.80300045 89.72200012 Tm [(results)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 43.97200012 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 48.47200012 89.72200012 Tm [(in)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 56.4129982 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 60.9129982 89.72200012 Tm [(multiple)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 96.28500366 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 100.78500366 89.72200012 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 141.70700073 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 146.20700073 89.72200012 Tm [(var)1(i)-1(a)1(n)-1(t)1(s.)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 181.94299316 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 186.44299316 89.72200012 Tm [([pr)1(ovided)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 228.09399414 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 232.59399414 89.72200012 Tm [(by)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 243.10600281 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(RefSeq,)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 32.32600021 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 36.82600021 105.3219986 Tm [(Aug)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 54.46099854 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 58.96099854 105.3219986 Tm [(20)-1(11)-1(])] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 83.07800293 105.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 109.94999695 cm q /GS2 gs 1 g 0.375 0.75 m 163.9750061 0.75 l 163.9750061 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 164.9750061 -0.25 l 164.9750061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 193 >> BDC BT /FAAACC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 194 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 164.7250061 0.75 m 422.375 0.75 l 422.375 16.35000038 l 164.7250061 16.35000038 l h f* Q q 1 0 0 1 164.3500061 0 cm -0.625 -0.25 m 259.0249939 -0.25 l 259.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 195 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB,)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 16.97200012 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 21.47200012 11.72200012 Tm [(IHC)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 37.09899902 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 126.30000305 cm q /GS2 gs 1 g 0.375 0.75 m 163.9750061 0.75 l 163.9750061 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 164.9750061 -0.25 l 164.9750061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 199 >> BDC BT /FAAACC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 204 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 164.7250061 0.75 m 422.375 0.75 l 422.375 16.35000038 l 164.7250061 16.35000038 l h f* Q q 1 0 0 1 164.3500061 0 cm -0.625 -0.25 m 259.0249939 -0.25 l 259.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 205 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(TOB)-1(1\(Pho)1(spho)1(-Ser1)-1(64)-1(\))] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 100.84100342 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 142.6499939 cm q /GS2 gs 1 g 0.375 0.75 m 163.9750061 0.75 l 163.9750061 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 164.9750061 -0.25 l 164.9750061 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 207 >> BDC BT /FAAACC 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 208 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 57.89400101 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 164.7250061 0.75 m 422.375 0.75 l 422.375 31.95000076 l 164.7250061 31.95000076 l h f* Q q 1 0 0 1 164.3500061 0 cm -0.625 -0.25 m 259.0249939 -0.25 l 259.0249939 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 209 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Pept)1(i)-1(d)1(e)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 32.97200012 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 37.47200012 11.72200012 Tm [(seque)-1(nce)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 78.31900024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 82.81900024 11.72200012 Tm [(aro)1(u)-1(nd)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 113.80000305 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 118.30000305 11.72200012 Tm [(ph)1(osph)1(orylation)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 189.07400513 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 193.57400513 11.72200012 Tm [(site)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 208.59500122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 213.09500122 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 221.93699646 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 226.43699646 11.72200012 Tm [(Se)-1(r)1(in)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(e)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 5.10599995 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 9.60599995 27.3220005 Tm [(16)-1(4\(A-)1(V)-1(-)1(S)-1(\(p)1(\)-P-)1(T\))] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 87.06400299 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 91.56400299 27.3220005 Tm [(derived)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 123.84600067 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 128.34599304 27.3220005 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 149.05700684 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 153.55700684 27.3220005 Tm [(Hu)-1(ma)1(n)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 185.01699829 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 189.51699829 27.3220005 Tm [(TOB)-1(1.)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 215.102005 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 174.59999084 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 164.3500061 0.75 m 164.3500061 109.94999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 164.3500061 110.69999695 m 164.3500061 126.29999542 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 164.3500061 127.04999542 m 164.3500061 142.6499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 164.3500061 143.3999939 m 164.3500061 174.59999084 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.75 0.75 m 422.75 174.59999084 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.125 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 110.32499695 m 422.375 110.32499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 126.67499542 m 422.375 126.67499542 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 143.0249939 m 422.375 143.0249939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 174.97499084 m 423.125 174.97499084 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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