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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.25 0 0 -90.25 0 90.25 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 79.72399902 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>-4<0005>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 151.48800659 23.67700005 Tm 0 Tr [(NFKB)1(IA)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 225.13600159 23.67700005 Tm 2 Tr [<0006>-4<0007>-4<0008>-4<0005>-4<0009>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 335.57598877 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 60.56000137 12.82499981 Tm [<000300040005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.68499756 12.82499981 Tm [(NFKB)1(IA)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 128.80000305 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 181.30000305 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.55000305 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(N)1(F)-1(K)1(BIA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.22299957 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.59700012 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.3690033 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.74299622 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.06399536 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.43800354 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.23399353 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(IK)1(BA;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.6969986 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.07099915 12.82499981 Tm [(MAD-3;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.93000031 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.30400085 12.82499981 Tm [(NFKB)1(I)] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.71800232 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0011>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001200130014>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<00150016>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<00170018>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0019>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(NFKB)1(IA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.48999786 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002000210022000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00230005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0024>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0025>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0026>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800220027>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 156.67500305 0.75 l 156.67500305 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 157.67500305 -0.25 l 157.67500305 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.42500305 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 157.42500305 156.75 l h f* Q q 1 0 0 1 157.05000305 0 cm -0.625 -0.25 m 266.375 -0.25 l 266.375 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(NF-kapp)1(a-B)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.15400696 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.65400696 11.72200012 Tm [(inhibit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.15799999 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.65799999 27.3220005 Tm [(fa)1(mi)-1(ly,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.90599823 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.40599823 27.3220005 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.50299835 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.00299835 27.3220005 Tm [(contain)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.05200195 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.55200195 27.3220005 Tm [(multiple)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.92399597 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.42399597 27.3220005 Tm [(ankrin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.22200012 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.72200012 27.3220005 Tm [(repeat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.44700623 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.94700623 27.3220005 Tm [(do)1(mains.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.10699463 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80700016 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.30699921 42.92200089 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.81399918 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.31399918 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.6210022 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.1210022 42.92200089 Tm [(interacts)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.96499634 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.46499634 42.92200089 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.86099243 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.36099243 42.92200089 Tm [(REL)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.80299377 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.30299377 42.92200089 Tm [(dimers)] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.59700012 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.09700012 42.92200089 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.17199707 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.67199707 42.92200089 Tm [(inhibit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.04598999 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(NF-kapp)1(a-B/REL)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.16500092 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.66500092 58.52199936 Tm [(complexe)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.41600037 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.91600037 58.52199936 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.01300049 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.51300049 58.52199936 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.03100586 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.53100586 58.52199936 Tm [(involved)] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.8999939 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.3999939 58.52199936 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.34100342 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.84100342 58.52199936 Tm [(inflam)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(mat)1(ory)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.68300056 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.18299866 74.12200165 Tm [(responses.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.51300049 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.01300049 74.12200165 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.81999969 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.31999969 74.12200165 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.82699585 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.32699585 74.12200165 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.63400269 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.13400269 74.12200165 Tm [(moves)] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.28500366 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.78500366 74.12200165 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.85699463 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.0010004 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.50099945 89.72200012 Tm [(cy)-1(t)1(oplas)1(m)] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.56900024 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.06900024 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.34600067 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.84600067 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.84700012 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.34700012 89.72200012 Tm [(nuc)-1(leu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.16499329 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.66499329 89.72200012 Tm [(via)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.75900269 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.25900269 89.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.23399353 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.73399353 89.72200012 Tm [(nuc)-1(lear)] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.2519989 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.7519989 89.72200012 Tm [(localizat)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.56199646 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(signal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.2329998 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.7329998 105.3219986 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.00999832 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.50999832 105.3219986 Tm [(CRM1-mediat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.25299835 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.75299835 105.3219986 Tm [(nuc)-1(lear)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.27099609 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.77099609 105.3219986 Tm [(expor)1(t.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.86500549 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.36500549 105.3219986 Tm [(Mutat)1(ions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.21400452 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.71400452 105.3219986 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.65499878 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.45600033 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.95599937 120.92199707 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.47200012 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.97200012 120.92199707 Tm [(ha)1(ve)] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.31900024 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.81900024 120.92199707 Tm [(been)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.3259964 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.8259964 120.92199707 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.51599884 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.01599884 120.92199707 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.95700073 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.45700073 120.92199707 Tm [(ec)-1(t)1(odermal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.2539978 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.7539978 120.92199707 Tm [(dyspla)1(sia)] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.09399414 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.59399414 120.92199707 Tm [(anhi)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(dr)1(otic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.1760006 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.6760006 136.52200317 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.0719986 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.5719986 136.52200317 Tm [(T-ce)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.03399658 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.53399658 136.52200317 Tm [(immun)-1(o)1(defic)-1(ienc)-1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.82499695 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.32499695 136.52200317 Tm [(auto)1(somal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.61099243 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.11099243 136.52200317 Tm [(do)1(mi)-1(na)1(n)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.83700562 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(disease.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.83800125 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.33800125 152.12199402 Tm [([pr)1(ovided)] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.98899841 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.48899841 152.12199402 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.00099945 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.50099945 152.12199402 Tm [(RefSeq,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.82699585 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.32699585 152.12199402 Tm [(Aug)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.96200562 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.46200562 152.12199402 Tm [(20)-1(11)-1(].)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.7460022 152.12199402 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 156.75 cm q /GS2 gs 1 g 0.375 0.75 m 156.67500305 0.75 l 156.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 157.67500305 -0.25 l 157.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.42500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 157.42500305 16.35000038 l h f* Q q 1 0 0 1 157.05000305 0 cm -0.625 -0.25 m 266.375 -0.25 l 266.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.97200012 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.47200012 11.72200012 Tm [(IF)] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.89900017 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 157.05000305 0.75 m 157.05000305 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 157.05000305 157.5 m 157.05000305 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.125 m 422.42498779 157.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 173.4750061 m 423.17498779 173.4750061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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