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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1499939 0 0 -90.05000305 0 90.05000305 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 89.69200134 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>-4<0005>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 161.45599365 23.67700005 Tm 0 Tr [(SAA1)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 215.16700745 23.67700005 Tm 2 Tr [<0006>-4<0007>-4<0008>-4<0005>-4<0009>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 325.60699463 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000A000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(SAA1)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 122.04699707 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 174.54699707 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.04699707 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(SAA)1(1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.03099823 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.40499878 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.17700195 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.55099487 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.87199402 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.2460022 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.04200745 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010001100120013000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(SAA1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.29699707 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001F002000210022000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0023>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0024>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0025000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800120026000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 348.65100098 m 416.75 348.65100098 l 416.75 379.85101318 l -1.45000005 379.85101318 l h f* Q q 1 0 0 1 0 348.65100098 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 379.85101318 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 407.79000854 cm q /GS2 gs 1 g 0.375 0.75 m 129.2749939 0.75 l 129.2749939 203.55000305 l 0.375 203.55000305 l h f* Q q -0.625 -0.25 m 130.2749939 -0.25 l 130.2749939 204.55000305 l -0.625 204.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 105.3219986 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 105.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 130.0249939 0.75 m 422.42498779 0.75 l 422.42498779 203.55000305 l 130.0249939 203.55000305 l h f* Q q 1 0 0 1 129.6499939 0 cm -0.625 -0.25 m 293.7749939 -0.25 l 293.7749939 204.55000305 l -0.625 204.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(serum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.96499634 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.46499634 11.72200012 Tm [(amyloid)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.90499878 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.40499878 11.72200012 Tm [(A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.73800659 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.23800659 11.72200012 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 277.32000732 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.84200001 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.34200001 27.3220005 Tm [(ap)1(olipop)1(roteins.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.68499756 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.18499756 27.3220005 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.99199677 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.49199677 27.3220005 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.99899292 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.49899292 27.3220005 Tm [(prepr)1(opro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.00300598 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.50300598 27.3220005 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.06399536 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.56399536 27.3220005 Tm [(pro)1(teolyticall)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 4.76399994 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.26399994 42.92200089 Tm [(pro)1(c)-1(essed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.98500061 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.48500061 42.92200089 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.55999756 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.05999756 42.92200089 Tm [(gene)-1(r)1(ate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.44599915 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.94599915 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.9469986 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.44700623 42.92200089 Tm [(mat)1(u)-1(r)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.29699707 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.79699707 42.92200089 Tm [(pro)1(tein)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.27000427 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.77000427 42.92200089 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.03199768 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.53199768 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.83898926 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 263.33898926 42.92200089 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.8999939 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 274.3999939 42.92200089 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 279.375 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(major)] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.96999931 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.46999931 58.52199936 Tm [(acute)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.96300125 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.46300125 58.52199936 Tm [(ph)1(ase)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.5 58.52199936 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.80699921 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.30699921 58.52199936 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.52900696 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.02900696 58.52199936 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.58999634 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.08999634 58.52199936 Tm [(hig)1(hly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.48399353 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.98399353 58.52199936 Tm [(expressed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.13800049 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.63800049 58.52199936 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.57899475 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.07899475 58.52199936 Tm [(respons)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.10599995 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.60599995 74.12200165 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.68099976 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.18099976 74.12200165 Tm [(inflammat)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.46800232 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.96800232 74.12200165 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.24500275 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.74500275 74.12200165 Tm [(tiss)1(u)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.477005 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.977005 74.12200165 Tm [(inju)-1(r)1(y)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.23399353 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.73399353 74.12200165 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.9960022 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.4960022 74.12200165 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.80299377 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.30299377 74.12200165 Tm [(also)] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.55999756 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.05999756 74.12200165 Tm [(plays)] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.10699463 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.60699463 74.12200165 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 282.12799072 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(impor)1(tant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.96099854 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.46099854 89.72200012 Tm [(role)] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.1210022 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.6210022 89.72200012 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.56199646 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.06199646 89.72200012 Tm [(HDL)] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.49700165 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.99700165 89.72200012 Tm [(metab)1(olism)] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.7230072 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.2230072 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.5 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 180 89.72200012 Tm [(cholesterol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.45700073 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.95700073 89.72200012 Tm [(ho)1(me)-1(os)1(tasi)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 6.33300018 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.83300018 105.3219986 Tm [(Hi)-1(g)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.48699951 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.98699951 105.3219986 Tm [(leve)-1(ls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.88000107 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.37999725 105.3219986 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.22200012 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.72200012 105.3219986 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.1780014 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.6780014 105.3219986 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.98500061 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.48500061 105.3219986 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.00300598 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.50300598 105.3219986 Tm [(asso)1(c)-1(iat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.63000488 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.13000488 105.3219986 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.52600098 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.02600098 105.3219986 Tm [(chronic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.69299316 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.19299316 105.3219986 Tm [(infla)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(mmat)1(ory)] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.11600113 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.61600113 120.92199707 Tm [(diseases)] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.45300293 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.95300293 120.92199707 Tm [(inc)-1(luding)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.8030014 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.30299377 120.92199707 Tm [(at)1(heroscle)-1(ro)1(sis,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.66900635 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.16900635 120.92199707 Tm [(rheumat)1(oid)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.43400574 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.93400574 120.92199707 Tm [(art)1(hrit)1(i)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(s,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 6.33300018 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.83300018 136.52200317 Tm [(Alz)1(he)-1(imer's)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.47800064 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.97799683 136.52200317 Tm [(disease)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.64900208 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.14900208 136.52200317 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.4260025 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.9260025 136.52200317 Tm [(Croh)1(n')-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.66499329 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.16499329 136.52200317 Tm [(disease.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.00300598 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.50300598 136.52200317 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.76499939 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.26499939 136.52200317 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.57200623 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.07200623 136.52200317 Tm [(may)] TJ ET EMC /P <> BDC BT 1 0 0 -1 273.24301147 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 277.74301147 136.52200317 Tm [(al)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(so)] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.88799953 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.38799953 152.12199402 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.24200058 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.74200058 152.12199402 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.71699905 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.21699905 152.12199402 Tm [(po)1(ten)-1(t)1(ial)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.80999756 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.30999756 152.12199402 Tm [(bioma)1(rk)-1(er)] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.46199799 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.96200562 152.12199402 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.24000549 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.74000549 152.12199402 Tm [(ce)-1(rt)1(ain)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.06500244 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.56500244 152.12199402 Tm [(tumor)1(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.38800049 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.88800049 152.12199402 Tm [(Alt)1(e)-1(rna)1(te)] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.49200439 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.99200439 152.12199402 Tm [(splici)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 167.72200012 Tm [(ng)] TJ ET EMC /P <> BDC BT 1 0 0 -1 11.30300045 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80300045 167.72200012 Tm [(results)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.97200012 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.47200012 167.72200012 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.4129982 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.9129982 167.72200012 Tm [(multiple)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.28500366 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.78500366 167.72200012 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.70700073 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.20700073 167.72200012 Tm [(var)1(i)-1(a)1(n)-1(t)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.7769928 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.2769928 167.72200012 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.49899292 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.99899292 167.72200012 Tm [(en)-1(cod)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.74899292 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.24899292 167.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.25 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.75 167.72200012 Tm [(same)] TJ ET EMC /P <> BDC BT 1 0 0 -1 283.42999268 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 183.32200623 Tm [(pro)1(tein)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.47299957 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.97299957 183.32200623 Tm [(A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.30599976 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.80599976 183.32200623 Tm [(pseudog)1(e)-1(ne)] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.36699677 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.86699677 183.32200623 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.70899963 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.20899963 183.32200623 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.66499329 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.16499329 183.32200623 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.68099976 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.18099976 183.32200623 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.74200439 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.24200439 183.32200623 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.93200684 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.43200684 183.32200623 Tm [(on)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.69999695 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.19999695 183.32200623 Tm [(chromos)1(ome)] TJ ET EMC /P <> BDC BT 1 0 0 -1 279.99499512 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 198.92199707 Tm [(11)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.72200012 198.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 203.55000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 129.6499939 0.75 m 129.6499939 203.55000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 203.55000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 203.92500305 m 423.17498779 203.92500305 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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