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gs 0 g [<000A000B000C000D000E>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(S100B)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 126.25099945 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 178.75100708 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 189.25100708 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(S100B)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 110.23500061 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 112.60900116 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 141.3809967 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 143.75500488 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 194.07600403 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 196.44999695 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 234.2460022 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000C000E>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(S100)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 83.79000092 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 86.16400146 12.82499981 Tm [(calci)-1(um)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 118.79699707 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 121.17099762 12.82499981 Tm [(bi)-1(nd)-1(in)-1(g)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 152.99899292 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 155.3730011 12.82499981 Tm [(protein)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 186.75500488 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 189.1289978 12.82499981 Tm [(B;)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 197.6499939 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 200.02400208 12.82499981 Tm [(NEF;)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 219.56300354 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 221.93699646 12.82499981 Tm [(S100;)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 245.53599548 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 247.91000366 12.82499981 Tm [(S100-B;)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 280.43499756 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 282.80899048 12.82499981 Tm [(S100beta)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 322.88598633 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011001200130010000E>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000E>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 63 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <</MCID 64 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000E>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(S100B)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 89.50099945 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 69 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001F002000210022000E>] TJ ET EMC /P <</MCID 70 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Rat)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 113.23400116 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0023>] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 77 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0024>] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 79 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0025000E>] TJ ET EMC /P <</MCID 80 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 84 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800130026000E>] TJ ET EMC /P <</MCID 85 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 94.73600006 12.82499981 Tm [(Mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 145.64700317 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 90 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 91 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 92 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 93 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 120.27500153 0.75 l 120.27500153 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 121.27500153 -0.25 l 121.27500153 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 94 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 95 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 121.02500153 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 121.02500153 172.3500061 l h f* Q q 1 0 0 1 120.65000153 0 cm -0.625 -0.25 m 302.7749939 -0.25 l 302.7749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 96 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 175.14100647 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 179.64100647 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 215.90499878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 220.40499878 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 229.24699402 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 233.74699402 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 247.7480011 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 252.2480011 11.72200012 Tm [(S1)-1(00)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 273.27600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 277.77600098 11.72200012 Tm [(fa)1(m)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ily)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 9.5539999 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 14.0539999 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 22.89599991 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 27.39599991 27.3220005 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 62.86899948 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 67.3690033 27.3220005 Tm [(containing)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 113.11599731 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 117.61599731 27.3220005 Tm [(2)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 122.89399719 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 127.39399719 27.3220005 Tm [(EF-h)1(and)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 162.83599854 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 167.33599854 27.3220005 Tm [(calc)-1(ium-b)1(i)-1(nd)1(in)-1(g)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 237.14300537 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 241.64300537 27.3220005 Tm [(mot)1(ifs.)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 270.99798584 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 275.49798584 27.3220005 Tm [(S1)-1(0)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(0)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 5.27799988 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 9.77799988 42.92200089 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 45.25099945 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 49.75099945 42.92200089 Tm [(are)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 63.26900101 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 67.76899719 42.92200089 Tm [(localized)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 105.45200348 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 109.95200348 42.92200089 Tm [(in)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 117.89299774 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 122.39299774 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 136.39399719 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 140.89399719 42.92200089 Tm [(cy)-1(t)1(oplas)1(m)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 184.96200562 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 189.46200562 42.92200089 Tm [(and/or)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 218.74299622 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 223.24299622 42.92200089 Tm [(nuc)-1(leu)-1(s)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 256.06100464 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 260.56100464 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 269.40301514 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 273.90301514 42.92200089 Tm [(a)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 278.87799072 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 283.37799072 42.92200089 Tm [(wi)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(de)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 10.86299992 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 15.36299992 58.52199936 Tm [(rang)1(e)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 40.18299866 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 44.68299866 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 53.52500153 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 58.02500153 58.52199936 Tm [(ce)-1(lls,)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 78.76699829 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 83.26699829 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 99.54399872 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 104.04399872 58.52199936 Tm [(involved)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 140.41299438 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 144.91299438 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 152.85400391 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 157.35400391 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 171.35499573 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 175.85499573 58.52199936 Tm [(regulat)1(i)-1(o)1(n)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 220.08599854 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 224.58599854 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 233.42799377 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 237.92799377 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 242.90299988 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 247.40299988 58.52199936 Tm [(number)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 281.21899414 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 285.71899414 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 294.56100464 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ce)-1(llular)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 30.76199913 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 35.26200104 74.12200165 Tm [(pro)1(c)-1(esses)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 77.39199829 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 81.89199829 74.12200165 Tm [(suc)-1(h)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 101.65899658 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 106.15899658 74.12200165 Tm [(as)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 115.30000305 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 119.80000305 74.12200165 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 134.21000671 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 138.71000671 74.12200165 Tm [(cy)-1(cle)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 160.0019989 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 164.5019989 74.12200165 Tm [(pro)1(gression)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 215.70300293 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 220.20300293 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 236.47999573 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 240.97999573 74.12200165 Tm [(dif)1(fe)-1(r)1(e)-1(nt)1(i)-1(a)1(ti)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(on.)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 13.43400002 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 17.93400002 89.72200012 Tm [(S1)-1(00)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 38.9620018 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 43.4620018 89.72200012 Tm [(gene)-1(s)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 69.14399719 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 73.64399719 89.72200012 Tm [(inc)-1(lude)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 104.90200043 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 109.40200043 89.72200012 Tm [(at)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 117.73000336 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 122.23000336 89.72200012 Tm [(least)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 142.2250061 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 146.7250061 89.72200012 Tm [(13)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 157.28100586 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 161.78100586 89.72200012 Tm [(members)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 202.21099854 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 206.71099854 89.72200012 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 231.80799866 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 236.30799866 89.72200012 Tm [(are)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 249.82600403 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 254.32600403 89.72200012 Tm [(located)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 286.14700317 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(as)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 9.14099979 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 13.64099979 105.3219986 Tm [(a)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 18.61599922 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 23.11599922 105.3219986 Tm [(cl)-1(ust)1(e)-1(r)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 51.63199997 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 56.13199997 105.3219986 Tm [(on)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 67.40000153 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 71.90000153 105.3219986 Tm [(chromos)1(ome)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 128.69500732 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 133.19500732 105.3219986 Tm [(1q2)-1(1;)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 156.95199585 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 161.45199585 105.3219986 Tm [(ho)1(weve)-1(r,)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 200.36099243 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 204.86099243 105.3219986 Tm [(th)1(is)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 220.31700134 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 224.81700134 105.3219986 Tm [(gene)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 246.33299255 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 250.83299255 105.3219986 Tm [(is)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 257.39401245 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 261.89401245 105.3219986 Tm [(located)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 293.71499634 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(at)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 8.32800007 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 12.82800007 120.92199707 Tm [(21)-1(q)1(2)-1(2.3.)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 49.30699921 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 53.80699921 120.92199707 Tm [(This)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 71.06900024 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 75.56900024 120.92199707 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 106.87599945 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 111.37599945 120.92199707 Tm [(may)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 129.54699707 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 134.04699707 120.92199707 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 169.78799438 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 174.28799438 120.92199707 Tm [(in)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 182.22900391 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 186.72900391 120.92199707 Tm [(Neu)-1(r)1(i)-1(t)1(e)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 218.98899841 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 223.48899841 120.92199707 Tm [(extension,)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 267.15701294 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 271.65701294 120.92199707 Tm [(pro)1(lif)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(eratio)1(n)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 30.53300095 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 35.03300095 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 43.875 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 48.375 136.52200317 Tm [(mel)-1(a)1(noma)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 93.95899963 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 98.45899963 136.52200317 Tm [(ce)-1(lls,)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 119.2009964 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 123.7009964 136.52200317 Tm [(st)1(i)-1(mulat)1(ion)] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 171.97900391 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 176.47900391 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 185.32099915 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 189.82099915 136.52200317 Tm [(Ca2+)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 212.76899719 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 217.26899719 136.52200317 Tm [(fluxes,)] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 244.33099365 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 248.83099365 136.52200317 Tm [(inhibitio)1(n)] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 289.86700439 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(of)] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 8.84200001 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 13.34200001 152.12199402 Tm [(PKC-)1(me)-1(d)1(iated)] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 75.35800171 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 79.85800171 152.12199402 Tm [(ph)1(osph)1(orylation,)] TJ ET EMC /P <</MCID 290 >> BDC BT 1 0 0 -1 152.79800415 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 291 >> BDC BT 1 0 0 -1 157.29800415 152.12199402 Tm [(ast)1(rocy)-1(t)1(osis)] TJ ET EMC /P <</MCID 292 >> BDC BT 1 0 0 -1 208.02799988 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 293 >> BDC BT 1 0 0 -1 212.52799988 152.12199402 Tm [(and)] TJ ET EMC /P <</MCID 294 >> BDC BT 1 0 0 -1 228.80499268 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 295 >> BDC BT 1 0 0 -1 233.30499268 152.12199402 Tm [(axo)1(n)-1(a)1(l)] TJ ET EMC /P <</MCID 296 >> BDC BT 1 0 0 -1 261.47799683 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 297 >> BDC BT 1 0 0 -1 265.97799683 152.12199402 Tm [(pro)1(life)] TJ ET EMC /P <</MCID 298 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(rat)1(ion,)] TJ ET EMC /P <</MCID 299 >> BDC BT 1 0 0 -1 27.59300041 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 300 >> BDC BT 1 0 0 -1 32.0929985 167.72200012 Tm [(and)] TJ ET EMC /P <</MCID 301 >> BDC BT 1 0 0 -1 48.36999893 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 302 >> BDC BT 1 0 0 -1 52.86999893 167.72200012 Tm [(inhibitio)1(n)] TJ ET EMC /P <</MCID 303 >> BDC BT 1 0 0 -1 93.90599823 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 304 >> BDC BT 1 0 0 -1 98.40599823 167.72200012 Tm [(of)] TJ ET EMC /P <</MCID 305 >> BDC BT 1 0 0 -1 107.2480011 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 306 >> BDC BT 1 0 0 -1 111.7480011 167.72200012 Tm [(mic)-1(r)1(otubule)] TJ ET EMC /P <</MCID 307 >> BDC BT 1 0 0 -1 163.94200134 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 308 >> BDC BT 1 0 0 -1 168.44200134 167.72200012 Tm [(assembly.)] TJ ET EMC /P <</MCID 309 >> BDC BT 1 0 0 -1 210.36099243 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 310 >> BDC BT 1 0 0 -1 214.86099243 167.72200012 Tm [(Chro)1(mosoma)1(l)] TJ ET EMC /P <</MCID 311 >> BDC BT 1 0 0 -1 275.42599487 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 312 >> BDC BT 1 0 0 -1 279.92599487 167.72200012 Tm [(rea)] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 120.65000153 0.75 m 120.65000153 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 172.7250061 m 423.17498779 172.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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