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[<000A000B000C000D000E>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(NEK)1(9)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 122.43199921 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 174.93200684 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 180.18200684 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(N)1(EK9)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 106.41500092 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 108.78900146 12.82499981 Tm [(m)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 117.17700195 12.82499981 Tm [(ou)-1(se)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 137.56199646 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 139.93600464 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 190.25700378 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 192.6309967 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 230.42700195 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 24 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000C000E>] TJ ET EMC /P <</MCID 25 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Ne)1(k8)1(;)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 87.90699768 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 90.28099823 12.82499981 Tm [(NERCC;)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 121.89399719 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 124.26799774 12.82499981 Tm [(NERCC1)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 158.39300537 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 32 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011001200130010000E>] TJ ET EMC /P <</MCID 33 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 34 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <</MCID 35 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 37 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <</MCID 38 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 39 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <</MCID 40 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 41 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 42 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<001C001D>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001F000E>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0020000E>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(NEK)1(9)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 85.68199921 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0021002200230024000E>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 64 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0025>] TJ ET EMC /P <</MCID 65 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 66 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0026>] TJ ET EMC /P <</MCID 67 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 68 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0027000E>] TJ ET EMC /P <</MCID 69 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 73 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800130028000E>] TJ ET EMC /P <</MCID 74 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 79 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 80 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 81 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 82 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 155.17500305 0.75 l 155.17500305 141.1499939 l 0.375 141.1499939 l h f* Q q -0.625 -0.25 m 156.17500305 -0.25 l 156.17500305 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 83 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 74.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 84 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 155.92500305 0.75 m 422.42498779 0.75 l 422.42498779 141.1499939 l 155.92500305 141.1499939 l h f* Q q 1 0 0 1 155.55000305 0 cm -0.625 -0.25 m 267.875 -0.25 l 267.875 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 85 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Pleiotro)1(pic)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 46.29199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 50.79199982 11.72200012 Tm [(regulat)1(or)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 90.51899719 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 95.01899719 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 103.86100006 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 108.36100006 11.72200012 Tm [(mito)1(tic)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 138.5249939 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 143.0249939 11.72200012 Tm [(pro)1(gression,)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 196.39199829 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 200.89199829 11.72200012 Tm [(pa)1(rticipat)1(i)-1(ng)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 255.48100281 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(in)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 7.94099998 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 12.44099998 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 26.44199944 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 30.94199944 27.3220005 Tm [(control)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 61.62900162 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 66.1289978 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 74.97100067 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 79.47100067 27.3220005 Tm [(spindle)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 110.58399963 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 115.08399963 27.3220005 Tm [(dynamics)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 155.63200378 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 160.13200378 27.3220005 Tm [(and)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 176.40899658 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 180.90899658 27.3220005 Tm [(chromos)1(ome)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 237.70399475 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 242.20399475 27.3220005 Tm [(sep)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ara)1(tion.)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 32.56800079 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 37.06800079 42.92200089 Tm [(Pho)1(spho)1(ryl)-1(a)1(tes)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 103.20999908 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 107.70999908 42.92200089 Tm [(dif)1(fe)-1(r)1(e)-1(nt)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 144.6499939 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 149.1499939 42.92200089 Tm [(hist)1(one)-1(s,)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 187.31199646 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 191.81199646 42.92200089 Tm [(mye)-1(lin)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 220.45100403 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 224.95100403 42.92200089 Tm [(ba)1(sic)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 246.7480011 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 251.2480011 42.92200089 Tm [(p)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(rot)1(e)-1(in,)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 27.72500038 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 32.22499847 58.52199936 Tm [(beta)1(-casei)-1(n,)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 84.16799927 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 88.66799927 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 104.94499969 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 109.44499969 58.52199936 Tm [(BICD2.)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 138.05799866 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 142.55799866 58.52199936 Tm [(Pho)1(spho)1(ryl)-1(a)1(tes)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 208.69999695 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 213.19999695 58.52199936 Tm [(hist)1(one)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 245.02999878 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 249.52999878 58.52199936 Tm [(H)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(3)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 5.27799988 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 9.77799988 74.12200165 Tm [(on)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 21.04599953 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 25.54599953 74.12200165 Tm [(serine)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 51.30199814 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 55.80199814 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 72.07900238 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 76.57900238 74.12200165 Tm [(th)1(re)-1(o)1(ni)-1(ne)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 118.33100128 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 122.83100128 74.12200165 Tm [(residues)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 158.50999451 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 163.00999451 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 179.28700256 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 183.78700256 74.12200165 Tm [(beta)1(-casei)-1(n)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 233.56399536 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 238.06399536 74.12200165 Tm [(on)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 249.33200073 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 253.83200073 74.12200165 Tm [(s)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(erin)-1(e)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 21.59000015 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 26.09000015 89.72200012 Tm [(residues.)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 63.93600082 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 68.43599701 89.72200012 Tm [(Impo)1(rta)1(n)-1(t)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 111.64700317 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 116.14700317 89.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 128.42500305 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 132.92500305 89.72200012 Tm [(G1/S)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 153.93499756 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 158.43499756 89.72200012 Tm [(tr)1(ansition)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 199.32200623 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 203.82200623 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 220.09899902 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 224.59899902 89.72200012 Tm [(S)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 229.79299927 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 234.29299927 89.72200012 Tm [(ph)1(as)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(e)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 5.10599995 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 9.60599995 105.3219986 Tm [(pro)1(gression.)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 62.97299957 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 67.47299957 105.3219986 Tm [(Pho)1(spho)1(ryl)-1(a)1(tes)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 133.61500549 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 138.11500549 105.3219986 Tm [(NEK6)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 161.3710022 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 165.8710022 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 182.147995 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 186.647995 105.3219986 Tm [(NEK7)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 209.90400696 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 214.40400696 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 230.68099976 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 235.18099976 105.3219986 Tm [(st)1(i)-1(mu)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(lat)1(e)-1(s)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 19.99500084 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 24.49500084 120.92199707 Tm [(th)1(e)-1(ir)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 44.32799911 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 48.82799911 120.92199707 Tm [(activit)1(y)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 79.30000305 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 83.80000305 120.92199707 Tm [(by)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 94.31199646 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 98.81199646 120.92199707 Tm [(rele)-1(a)1(sin)-1(g)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 137.69500732 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 142.19500732 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 156.19599915 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 160.69599915 120.92199707 Tm [(auto)1(in)-1(h)1(ibito)1(ry)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 221.58700562 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 226.08700562 120.92199707 Tm [(func)-1(t)1(io)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(ns)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 9.71199989 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 14.21199989 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 23.05400085 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 27.55400085 136.52200317 Tm [(Ty)-1(r)1(-10)-1(8)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 60.63999939 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 65.13999939 136.52200317 Tm [(and)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 81.41699982 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 85.91699982 136.52200317 Tm [(Ty)-1(r)1(-97)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 113.72599792 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 118.22599792 136.52200317 Tm [(respec)-1(t)1(ive)-1(ly.)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 171.20599365 136.52200317 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 141.1499939 cm q /GS2 gs 1 g 0.375 0.75 m 155.17500305 0.75 l 155.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 156.17500305 -0.25 l 156.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 218 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 219 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 155.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 155.92500305 16.35000038 l h f* Q q 1 0 0 1 155.55000305 0 cm -0.625 -0.25 m 267.875 -0.25 l 267.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 220 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB,)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 16.97200012 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 21.47200012 11.72200012 Tm [(IF,)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 31.06500053 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 35.56499863 11.72200012 Tm [(FC)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 46.36700058 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 157.5 cm q /GS2 gs 1 g 0.375 0.75 m 155.17500305 0.75 l 155.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 156.17500305 -0.25 l 156.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 226 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 231 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 155.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 155.92500305 16.35000038 l h f* Q q 1 0 0 1 155.55000305 0 cm -0.625 -0.25 m 267.875 -0.25 l 267.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 232 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(NEK9)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 23.25600052 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 155.55000305 0.75 m 155.55000305 141.1499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 155.55000305 141.8999939 m 155.55000305 157.5 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 155.55000305 158.25 m 155.55000305 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 141.5249939 m 422.42498779 141.5249939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.875 m 422.42498779 157.875 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 174.2250061 m 423.17498779 174.2250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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