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gs 0 g [<000A000B000C000D000E>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(S100A4)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 131.93699646 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 184.43699646 12.82499981 Tm [(   )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 200.18699646 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(S100A)1(4)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 115.91999817 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 118.29399872 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 147.06599426 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 149.44000244 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 199.76100159 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 202.13499451 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 239.93099976 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000C000E>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(S100)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 83.79000092 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 86.16400146 12.82499981 Tm [(calci)-1(um)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 118.79699707 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 121.17099762 12.82499981 Tm [(bi)-1(nd)-1(in)-1(g)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 152.99899292 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 155.3730011 12.82499981 Tm [(protein)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 186.75500488 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 189.1289978 12.82499981 Tm [(A4)1(;)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 203.33599854 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 205.71000671 12.82499981 Tm [(42A)1(;)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 225.23899841 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 227.61300659 12.82499981 Tm [(18A)1(2;)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 252.46299744 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 254.83700562 12.82499981 Tm [(CAP)1(L)-1(;)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 279.15899658 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 281.5329895 12.82499981 Tm [(FS)-1(P1)1(;)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 304.73800659 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 307.11199951 12.82499981 Tm [(MTS)-1(1;)] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 334.1619873 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 336.53601074 12.82499981 Tm [(P9)1(KA;)] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 361.62200928 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 363.9960022 12.82499981 Tm [(PEL98)] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 389.60501099 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011001200130010000E>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <</MCID 52 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 64 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000E>] TJ ET EMC /P <</MCID 65 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 69 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <</MCID 70 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 71 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000E>] TJ ET EMC /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(S100A4)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 95.18699646 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001F002000210022000E>] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 79 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0023>] TJ ET EMC /P <</MCID 80 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 81 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0024>] TJ ET EMC /P <</MCID 82 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 83 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0025000E>] TJ ET EMC /P <</MCID 84 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 88 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800130026000E>] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 94.73600006 12.82499981 Tm [(Mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 145.64700317 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 94 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 95 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 96 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 97 >> BDC BT 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 127.02500153 0.75 l 127.02500153 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 128.0249939 -0.25 l 128.0249939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 98 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 99 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 127.77500153 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 127.77500153 172.3500061 l h f* Q q 1 0 0 1 127.40000153 0 cm -0.625 -0.25 m 296.0249939 -0.25 l 296.0249939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 100 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 175.14100647 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 179.64100647 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 215.90499878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 220.40499878 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 229.24699402 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 233.74699402 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 247.7480011 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 252.2480011 11.72200012 Tm [(S1)-1(00)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 273.27600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 277.77600098 11.72200012 Tm [(fa)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(mily)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 17.98699951 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 22.48699951 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 31.32900047 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 35.82899857 27.3220005 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 71.30200195 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 75.80200195 27.3220005 Tm [(containing)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 121.5490036 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 126.0490036 27.3220005 Tm [(2)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 131.32699585 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 135.82699585 27.3220005 Tm [(EF-h)1(and)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 171.26899719 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 175.76899719 27.3220005 Tm [(calc)-1(ium-b)1(i)-1(nd)1(in)-1(g)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 245.57600403 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 250.07600403 27.3220005 Tm [(mot)1(ifs.)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 279.43099976 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(S1)-1(00)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 21.02799988 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 25.52799988 42.92200089 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 61.00099945 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 65.50099945 42.92200089 Tm [(are)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 79.01899719 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 83.51899719 42.92200089 Tm [(localized)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 121.20200348 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 125.70200348 42.92200089 Tm [(in)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 133.64300537 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 138.14300537 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 152.14399719 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 156.64399719 42.92200089 Tm [(cy)-1(t)1(oplas)1(m)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 200.71200562 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 205.21200562 42.92200089 Tm [(and/or)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 234.49299622 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 238.99299622 42.92200089 Tm [(nuc)-1(leu)-1(s)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 271.81100464 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 276.31100464 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 285.15301514 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 4.9749999 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 9.47500038 58.52199936 Tm [(wid)1(e)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 29.8390007 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 34.3390007 58.52199936 Tm [(rang)1(e)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 59.1590004 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 63.6590004 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 72.50099945 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 77.00099945 58.52199936 Tm [(ce)-1(lls,)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 97.74299622 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 102.24299622 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 118.51999664 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 123.01999664 58.52199936 Tm [(involved)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 159.38900757 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 163.88900757 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 171.83000183 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 176.33000183 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 190.33099365 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 194.83099365 58.52199936 Tm [(regulat)1(i)-1(o)1(n)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 239.06199646 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 243.56199646 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 252.40400696 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 256.9039917 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 261.8789978 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 266.3789978 58.52199936 Tm [(num)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ber)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 14.29100037 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 18.79100037 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 27.63299942 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 32.13299942 74.12200165 Tm [(ce)-1(llular)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 62.89500046 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 67.39499664 74.12200165 Tm [(pro)1(c)-1(esses)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 109.52500153 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 114.02500153 74.12200165 Tm [(suc)-1(h)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 133.79200745 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 138.29200745 74.12200165 Tm [(as)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 147.43299866 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 151.93299866 74.12200165 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 166.34300232 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 170.84300232 74.12200165 Tm [(cy)-1(cle)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 192.13499451 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 196.63499451 74.12200165 Tm [(pro)1(gression)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 247.83599854 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 252.33599854 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 268.61300659 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 273.11300659 74.12200165 Tm [(dif)1(f)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ere)-1(nt)1(iation.)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 49.09999847 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 53.59999847 89.72200012 Tm [(S1)-1(00)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 74.62799835 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 79.12799835 89.72200012 Tm [(gene)-1(s)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 104.80999756 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 109.30999756 89.72200012 Tm [(inc)-1(lude)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 140.56799316 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 145.06799316 89.72200012 Tm [(at)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 153.39599609 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 157.89599609 89.72200012 Tm [(least)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 177.89100647 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 182.39100647 89.72200012 Tm [(13)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 192.94700623 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 197.44700623 89.72200012 Tm [(members)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 237.8769989 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 242.3769989 89.72200012 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 267.47399902 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 271.97399902 89.72200012 Tm [(are)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 285.49200439 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(located)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 31.82099915 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 36.32099915 105.3219986 Tm [(as)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 45.4620018 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 49.9620018 105.3219986 Tm [(a)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 54.93700027 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 59.43700027 105.3219986 Tm [(cl)-1(ust)1(e)-1(r)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 87.95300293 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 92.45300293 105.3219986 Tm [(on)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 103.72100067 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 108.22100067 105.3219986 Tm [(chromos)1(ome)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 165.01600647 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 169.51600647 105.3219986 Tm [(1q2)-1(1.)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 193.272995 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 197.772995 105.3219986 Tm [(This)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 215.03500366 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 219.53500366 105.3219986 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 250.84199524 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 255.34199524 105.3219986 Tm [(may)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 273.51300049 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 278.01300049 105.3219986 Tm [(fu)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(nc)-1(t)1(ion)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 27.07500076 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 31.57500076 120.92199707 Tm [(in)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 39.51599884 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 44.01599884 120.92199707 Tm [(mot)1(il)-1(it)1(y)-1(,)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 78.99199677 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 83.49199677 120.92199707 Tm [(invasion,)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 121.1269989 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 125.6269989 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 141.90400696 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 146.40400696 120.92199707 Tm [(tub)1(u)-1(lin)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 176.93299866 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 181.43299866 120.92199707 Tm [(po)1(l)-1(ymerizat)1(ion.)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 248.01499939 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 252.51499939 120.92199707 Tm [(Chro)1(mo)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(soma)1(l)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 25.69000053 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 30.19000053 136.52200317 Tm [(rearra)1(n)-1(g)1(e)-1(ments)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 98.56900024 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 103.06900024 136.52200317 Tm [(and)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 119.34600067 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 123.84600067 136.52200317 Tm [(alt)1(e)-1(red)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 153.9750061 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 158.4750061 136.52200317 Tm [(expression)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 204.42900085 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 208.92900085 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 217.77099609 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 222.27099609 136.52200317 Tm [(th)1(is)] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 237.727005 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 242.227005 136.52200317 Tm [(gene)] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 263.74301147 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 268.24301147 136.52200317 Tm [(ha)1(v)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(e)] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 5.10599995 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 9.60599995 152.12199402 Tm [(been)] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 31.11300087 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 35.61299896 152.12199402 Tm [(implicated)] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 80.68299866 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 85.18299866 152.12199402 Tm [(in)] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 93.12400055 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 97.62400055 152.12199402 Tm [(tumor)] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 124.11399841 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 290 >> BDC BT 1 0 0 -1 128.61399841 152.12199402 Tm [(metast)1(asis.)] TJ ET EMC /P <</MCID 291 >> BDC BT 1 0 0 -1 175.86799622 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 292 >> BDC BT 1 0 0 -1 180.36799622 152.12199402 Tm [(Multiple)] TJ ET EMC /P <</MCID 293 >> BDC BT 1 0 0 -1 216.1000061 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 294 >> BDC BT 1 0 0 -1 220.6000061 152.12199402 Tm [(alt)1(e)-1(rnat)1(ive)-1(ly)] TJ ET EMC /P <</MCID 295 >> BDC BT 1 0 0 -1 273.12298584 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 296 >> BDC BT 1 0 0 -1 277.62298584 152.12199402 Tm [(sp)] TJ ET EMC /P <</MCID 297 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(lic)-1(ed)] TJ ET EMC /P <</MCID 298 >> BDC BT 1 0 0 -1 20.16699982 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 299 >> BDC BT 1 0 0 -1 24.66699982 167.72200012 Tm [(var)1(i)-1(a)1(n)-1(t)1(s,)] TJ ET EMC /P <</MCID 300 >> BDC BT 1 0 0 -1 60.40299988 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 301 >> BDC BT 1 0 0 -1 64.90299988 167.72200012 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <</MCID 302 >> BDC BT 1 0 0 -1 105.24500275 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 303 >> BDC BT 1 0 0 -1 109.74500275 167.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 304 >> BDC BT 1 0 0 -1 123.7460022 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 305 >> BDC BT 1 0 0 -1 128.2460022 167.72200012 Tm [(same)] TJ ET EMC /P <</MCID 306 >> BDC BT 1 0 0 -1 150.92599487 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 307 >> BDC BT 1 0 0 -1 155.42599487 167.72200012 Tm [(pro)1(tein)-1(,)] TJ ET EMC /P <</MCID 308 >> BDC BT 1 0 0 -1 188.89900208 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 309 >> BDC BT 1 0 0 -1 193.39900208 167.72200012 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 310 >> BDC BT 1 0 0 -1 213.7460022 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 311 >> BDC BT 1 0 0 -1 218.2460022 167.72200012 Tm [(been)] TJ ET EMC /P <</MCID 312 >> BDC BT 1 0 0 -1 239.75300598 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 313 >> BDC BT 1 0 0 -1 244.25300598 167.72200012 Tm [(identified.)] TJ ET EMC /P <</MCID 314 >> BDC BT 1 0 0 -1 287.3500061 167.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 127.40000153 0.75 m 127.40000153 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 172.7250061 m 423.17498779 172.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
endobj
6 0 obj
<</Length1 127 0 R/Length 29008>>stream
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