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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 124.48600006 l -90 124.48600006 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 18 1 cm q 270 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q BT 1 0 0 -1 288 92.5 Tm /GS1 gs 0 g [( )] TJ ET q 1 0 0 1 0 102.5 cm Q Q EMC q 1 0 0 1 90 167.03599548 cm /P <> BDC BT /FAAABC 22 Tf 1 0 0 -1 95.92900085 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>] TJ ET EMC /P <> BDC BT /FAAABH 22 Tf 1 0 0 -1 145.60499573 23.67700005 Tm 0 Tr [(PLCG)-1(2)] TJ ET EMC /P <> BDC BT /FAAABC 22 Tf 1 0 0 -1 208.92999268 23.67700005 Tm 2 Tr [<0005>-4<0006>-4<0007>-4<0004>-4<0008>] TJ ET EMC /P <> BDC BT /FAAABH 22 Tf 1 0 0 -1 319.36999512 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 86.625 12.82499981 Tm [(PLCG2)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 116.63300323 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 169.13299561 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.63299561 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(P)1(L)-1(CG2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.11599731 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.48999786 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.13999939 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.51400757 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.07299805 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.44700623 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.24299622 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000B000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(PLCG2;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.19300079 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.56700134 12.82499981 Tm [(AP)1(L)-1(A)1(ID;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.47200012 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.84599304 12.82499981 Tm [(FC)-1(A)1(S)-1(3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.49099731 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0015000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<001B001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001F000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(PLCG2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.38300323 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0020002100220023000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.96800232 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.34199524 12.82499981 Tm [(Rat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.58999634 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0024>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0025>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0026000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700120027000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 145.0249939 0.75 l 145.0249939 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 146.0249939 -0.25 l 146.0249939 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 145.7749939 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 145.7749939 156.75 l h f* Q q 1 0 0 1 145.3999939 0 cm -0.625 -0.25 m 278.0249939 -0.25 l 278.0249939 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Pho)1(spho)1(in)-1(o)1(sitide-sp)1(e)-1(cific)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.63200378 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.13200378 11.72200012 Tm [(ph)1(osph)1(olipase)] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.10600281 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.60600281 11.72200012 Tm [(C)] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.6269989 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.1269989 11.72200012 Tm [(\(PLC\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.28399658 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.78399658 11.72200012 Tm [(plays)] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.83099365 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.33099365 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.30599976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.80599976 11.72200012 Tm [(sig)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(nific)-1(a)1(n)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.84300041 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.3429985 27.3220005 Tm [(role)] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.00299835 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.50299835 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.44400024 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.94400024 27.3220005 Tm [(tr)1(ansme)-1(mb)1(rane)] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.20399475 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.70399475 27.3220005 Tm [(signaling.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.80200195 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.30200195 27.3220005 Tm [(In)] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.49299622 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.99299622 27.3220005 Tm [(response)] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.99000549 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.49000549 27.3220005 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.56500244 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.06500244 27.3220005 Tm [(ex)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(tr)1(ac)-1(ellul)-1(a)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.52600098 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.02600098 42.92200089 Tm [(st)1(i)-1(muli)] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.70899963 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.20899963 42.92200089 Tm [(suc)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.97599792 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.47599792 42.92200089 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.61699677 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.11699677 42.92200089 Tm [(ho)1(rmone)-1(s,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.95599365 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.45599365 42.92200089 Tm [(gr)1(owt)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.37199402 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.87199402 42.92200089 Tm [(fa)1(c)-1(t)1(ors)] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.15699768 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.65699768 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.93400574 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.43399048 42.92200089 Tm [(ne)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(urot)1(ransmitt)1(e)-1(r)1(s,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.58999634 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.08999634 58.52199936 Tm [(PLC)] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.23600006 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.73600006 58.52199936 Tm [(hydro)1(ly)-1(z)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.81300354 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.31300354 58.52199936 Tm [(ph)1(osph)1(atid)1(y)-1(linosito)1(l)] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.11099243 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.61099243 58.52199936 Tm [(4,5)-1(-)1(bis)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ph)1(osph)1(ate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.90100098 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.40100098 74.12200165 Tm [(\(PIP2\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.34899902 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.84899902 74.12200165 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.9240036 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.4240036 74.12200165 Tm [(gene)-1(r)1(ate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.80999756 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.30999756 74.12200165 Tm [(tw)1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.49099731 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.99099731 74.12200165 Tm [(sec)-1(o)1(n)-1(d)1(ary)] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.97599792 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.47599792 74.12200165 Tm [(messe)-1(ng)1(e)-1(rs:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.63198853 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 263.13198853 74.12200165 Tm [(i)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(nosito)1(l)] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.29800034 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.79800034 89.72200012 Tm [(1,4)-1(,)1(5)-1(-)1(triph)1(osph)1(ate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.94400024 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.44400024 89.72200012 Tm [(\(IP3\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.88499451 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.38499451 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.66200256 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.16200256 89.72200012 Tm [(dia)1(c)-1(ylglyc)-1(erol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.04899597 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.54899597 89.72200012 Tm [(\(DA)1(G\).)] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.60800171 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.10800171 89.72200012 Tm [(At)] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.79400635 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(least)] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.99500084 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.49500084 105.3219986 Tm [(fo)1(u)-1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.31900024 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.81900024 105.3219986 Tm [(fa)1(mi)-1(lies)] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.80400085 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.30400085 105.3219986 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.14600372 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.64600372 105.3219986 Tm [(PLCs)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.95800018 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.45800018 105.3219986 Tm [(ha)1(ve)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.80499268 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.30499268 105.3219986 Tm [(been)] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.81199646 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.31199646 105.3219986 Tm [(identified:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.40899658 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.90899658 105.3219986 Tm [(PLC)] TJ ET EMC /P <> BDC BT /FAAADE 9 Tf 1 0 0 -1 237.05499268 105.3219986 Tm [<002B>] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 242.46499634 105.3219986 Tm [(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.63200378 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.13200378 105.3219986 Tm [(PLC)] TJ ET EMC /P <> BDC BT /FAAADE 9 Tf 1 0 0 -1 0 120.92199707 Tm [<002C>] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 5.09800005 120.92199707 Tm [(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 7.26499987 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 11.76500034 120.92199707 Tm [(PLC)] TJ ET EMC /P <> BDC BT /FAAADE 9 Tf 1 0 0 -1 27.9109993 120.92199707 Tm [<002D>] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 33.61899948 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.11899948 120.92199707 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.39599991 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.89599991 120.92199707 Tm [(PLC)] TJ ET EMC /P <> BDC BT /FAAADE 9 Tf 1 0 0 -1 75.04199982 120.92199707 Tm [<002E>] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 79.32700348 120.92199707 Tm [(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.4940033 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.9940033 120.92199707 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.8010025 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.3010025 120.92199707 Tm [(PLC)] TJ ET EMC /P <> BDC BT /FAAADE 9 Tf 1 0 0 -1 122.4469986 120.92199707 Tm [<002B>] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 127.85700226 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.35699463 120.92199707 Tm [(subf)1(amily)] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.89900208 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.39900208 120.92199707 Tm [(inc)-1(ludes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.82299805 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.32299805 120.92199707 Tm [(fo)1(u)-1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.14700317 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.64700317 120.92199707 Tm [(memb)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(ers,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.875 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.375 136.52200317 Tm [(PLC)] TJ ET EMC /P <> BDC BT /FAAADE 9 Tf 1 0 0 -1 35.52099991 136.52200317 Tm [<002B>] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 40.93099976 136.52200317 Tm [(1-4.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.54700089 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.04700089 136.52200317 Tm [(All)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.16999817 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.66999817 136.52200317 Tm [(fo)1(u)-1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.4940033 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.9940033 136.52200317 Tm [(members)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.42399597 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.92399597 136.52200317 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.76600647 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.26600647 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.26699829 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.76699829 136.52200317 Tm [(subf)1(amily)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.30900574 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.80900574 136.52200317 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.32699585 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.82699585 136.52200317 Tm [(activat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.86299992 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.36299992 152.12199402 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.875 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT /FAAADE 9 Tf 1 0 0 -1 30.375 152.12199402 Tm [<0030>] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 36.36899948 152.12199402 Tm [(-)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.26300049 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.76300049 152.12199402 Tm [(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.92100143 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT /FAAADE 9 Tf 1 0 0 -1 58.42100143 152.12199402 Tm [<002B>] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 63.83100128 152.12199402 Tm [(-)] TJ ET EMC /P <> BDC BT /FAAADE 9 Tf 1 0 0 -1 67.72499847 152.12199402 Tm [<002C>] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 72.82299805 152.12199402 Tm [(-sub)1(u)-1(nit)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.18199921 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.68199921 152.12199402 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.52400208 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.02400208 152.12199402 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.0249939 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.5249939 152.12199402 Tm [(heterot)1(rime)-1(r)1(ic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.85899353 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.35899353 152.12199402 Tm [(G-)1(prot)1(ei)-1(ns.)1(P)] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 145.3999939 0.75 m 145.3999939 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 157.125 m 423.17498779 157.125 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
endstream
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6 0 obj
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