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EMC /P <</MCID 4 >> BDC BT 1 0 0 -1 -88 43.75799942 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -88 61.9640007 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -35.5 61.9640007 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -25 61.9640007 Tm [<00030004>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -1.375 61.9640007 Tm [(KDM2A)] TJ ET EMC /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 33.54000092 61.9640007 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 86.03999329 61.9640007 Tm [(  )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 96.53999329 61.9640007 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 82.6780014 cm /P <</Lang (zh-CN) /MCID 12 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 13 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(K)1(DM2A)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 116.02300262 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 118.39700317 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 144.04699707 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 146.42100525 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 189.97999573 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 192.35400391 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 230.1499939 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 116.21700287 cm /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 24 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 25 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(lysi)-1(ne)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 87.41999817 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 89.79399872 12.82499981 Tm [(deme)1(th)-1(y)1(l)-1(ase)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 144.70399475 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 147.07800293 12.82499981 Tm [(2A)1(;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 161.28500366 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 163.65899658 12.82499981 Tm [(FBL)-1(7;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 186.74099731 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 189.11500549 12.82499981 Tm [(CXXC8;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 219.34399414 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 221.71800232 12.82499981 Tm [(FBL)-1(11)1(;)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 250.1210022 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 252.49499512 12.82499981 Tm [(FBXL)-1(11;)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 286.34799194 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 288.72198486 12.82499981 Tm [(JHDM1A;)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 328.25601196 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 330.63000488 12.82499981 Tm [(LIL)-1(IN)1(A)] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 357.60299683 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 149.7559967 cm /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 183.29499817 cm /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0004>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0014000D>] TJ ET EMC /P <</MCID 52 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(KDM2A)] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 95.29000092 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 97.66400146 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 216.83399963 cm /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0015>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000D>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 250.3730011 cm /P <</Lang (zh-CN) /MCID 64 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C>] TJ ET EMC /P <</MCID 65 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 66 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000D>] TJ ET EMC /P <</MCID 67 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 283.9119873 cm /P <</Lang (zh-CN) /MCID 71 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 128.3480072 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 317.45098877 cm /P <</Lang (zh-CN) /MCID 77 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0022>] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 79 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0023>] TJ ET EMC /P <</MCID 80 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 81 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0024000D>] TJ ET EMC /P <</MCID 82 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 350.98999023 cm /P <</Lang (zh-CN) /MCID 86 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0006000700120025000D>] TJ ET EMC /P <</MCID 87 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 384.5289917 m 416.75 384.5289917 l 416.75 415.72900391 l -1.45000005 415.72900391 l h f* Q q 1 0 0 1 0 384.5289917 cm /P <</MCID 92 >> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 93 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 94 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 415.72900391 cm /P <</MCID 95 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 443.66799927 cm q 1 g 0.375 0.75 m 131.17500305 0.75 l 131.17500305 141.1499939 l 0.375 141.1499939 l h f* Q q -0.625 -0.25 m 132.17500305 -0.25 l 132.17500305 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 96 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 74.12200165 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 97 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 131.92500305 0.75 m 422.42498779 0.75 l 422.42498779 141.1499939 l 131.92500305 141.1499939 l h f* Q q 1 0 0 1 131.55000305 0 cm -0.625 -0.25 m 291.875 -0.25 l 291.875 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 98 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(This)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(F-bo)1(x)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 194.98300171 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 199.48300171 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 230.78999329 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 235.28999329 11.72200012 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 261.37200928 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 265.87200928 11.72200012 Tm [(wh)1(i)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ch)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 10.05500031 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 14.55500031 27.3220005 Tm [(is)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 21.11599922 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 25.61599922 27.3220005 Tm [(chara)1(c)-1(terized)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 83.14900208 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 87.64900208 27.3220005 Tm [(by)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 98.16100311 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 102.66100311 27.3220005 Tm [(an)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 113.18199921 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 117.68199921 27.3220005 Tm [(ap)1(prox)1(i)-1(ma)1(tely)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 179.29299927 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 183.79299927 27.3220005 Tm [(40)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 194.34899902 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 198.84899902 27.3220005 Tm [(amino)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 225.91900635 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 230.41900635 27.3220005 Tm [(acid)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 248.05900574 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 252.55900574 27.3220005 Tm [(mot)1(if,)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 277.74798584 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 14.0010004 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 18.50099945 42.92200089 Tm [(F-bo)1(x.)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 45.37400055 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 49.87400055 42.92200089 Tm [(The)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 65.68099976 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 70.18099976 42.92200089 Tm [(F-bo)1(x)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 94.88700104 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 99.38700104 42.92200089 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 134.86000061 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 139.36000061 42.92200089 Tm [(constitut)1(e)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 182.41299438 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 186.91299438 42.92200089 Tm [(one)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 203.28700256 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 207.78700256 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 216.6289978 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 221.1289978 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 235.13000488 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 239.63000488 42.92200089 Tm [(fo)1(u)-1(r)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 257.45401001 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 261.95401001 42.92200089 Tm [(subu)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(nits)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 15.46000004 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 19.95999908 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 28.80200005 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 33.30199814 58.52199936 Tm [(ubiquitin)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 71.98300171 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 76.48300171 58.52199936 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 107.79000092 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 112.29000092 58.52199936 Tm [(ligase)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 137.08399963 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 141.58399963 58.52199936 Tm [(complex)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 178.06300354 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 182.56300354 58.52199936 Tm [(calle)-1(d)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 207.70399475 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 212.20399475 58.52199936 Tm [(SCFs)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 232.36599731 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 236.86599731 58.52199936 Tm [(\(SKP1-cul)-1(li)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(n-F-b)1(ox\),)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 39.31800079 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 43.81800079 74.12200165 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 68.91500092 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 73.41500092 74.12200165 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 109.15599823 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 113.65599823 74.12200165 Tm [(in)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 121.59700012 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 126.09700012 74.12200165 Tm [(ph)1(osph)1(orylation-)1(depen)-1(d)1(e)-1(nt)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 247.78999329 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 252.28999329 74.12200165 Tm [(ubiquit)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(inatio)1(n)-1(.)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 32.09799957 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 36.59799957 89.72200012 Tm [(The)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 52.40499878 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 56.90499878 89.72200012 Tm [(F-bo)1(x)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 81.61100006 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 86.11100006 89.72200012 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 121.58399963 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 126.08399963 89.72200012 Tm [(are)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 139.602005 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 144.102005 89.72200012 Tm [(divid)1(e)-1(d)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 175.99299622 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 180.49299622 89.72200012 Tm [(into)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 197.50900269 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 202.00900269 89.72200012 Tm [(3)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 207.28700256 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 211.78700256 89.72200012 Tm [(cl)-1(a)1(sses:)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 243.44099426 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 247.94099426 89.72200012 Tm [(Fbw)1(s)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 269.74200439 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 274.24200439 89.72200012 Tm [(c)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(onta)1(in)-1(ing)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 41.23400116 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 45.73400116 105.3219986 Tm [(WD)1(-40)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 76.1969986 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 80.6969986 105.3219986 Tm [(do)1(mains,)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 119.85700226 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 124.35700226 105.3219986 Tm [(Fbls)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 141.44700623 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 145.94700623 105.3219986 Tm [(containing)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 191.69400024 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 196.19400024 105.3219986 Tm [(leu)-1(cine)-1(-)1(ric)-1(h)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 246.58200073 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 251.08200073 105.3219986 Tm [(repeats)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(,)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 2.16700006 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 6.66699982 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 22.94400024 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 27.44400024 120.92199707 Tm [(Fbxs)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 46.70100021 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 51.20100021 120.92199707 Tm [(containing)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 96.94799805 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 101.44799805 120.92199707 Tm [(either)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 126.38700104 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 130.88699341 120.92199707 Tm [(dif)1(fe)-1(r)1(e)-1(nt)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 167.82699585 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 172.32699585 120.92199707 Tm [(pro)1(tein)-1(-)1(pro)1(tein)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 238.83399963 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 243.33399963 120.92199707 Tm [(interacti)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(on)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 11.26799965 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 15.76799965 136.52200317 Tm [(mod)1(u)-1(les)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 52.89300156 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 57.39300156 136.52200317 Tm [(or)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 66.5510025 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 71.0510025 136.52200317 Tm [(no)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 82.31900024 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 86.81900024 136.52200317 Tm [(rec)-1(o)1(gnizable)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 141.94400024 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 146.44400024 136.52200317 Tm [(mot)1(ifs.)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 175.79899597 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 180.29899597 136.52200317 Tm [(The)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 196.10600281 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 200.60600281 136.52200317 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 231.91299438 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 236.41299438 136.52200317 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 273.92001343 136.52200317 Tm [( )] TJ ET EMC Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 141.1499939 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 131.55000305 0.75 m 131.55000305 141.1499939 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 141.1499939 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 141.5249939 m 423.17498779 141.5249939 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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