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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 86.24900055 23.67700005 Tm 0 g [(RBM5)] TJ ET EMC /P <</MCID 1 >> BDC BT 1 0 0 -1 141.34599304 23.67700005 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 2 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 152.34599304 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 3 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 329.04998779 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 4 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 63 12.82499981 Tm [(RBM5)] TJ ET EMC /P <</MCID 7 >> BDC BT 1 0 0 -1 88.71199799 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 93.96199799 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 177.96200562 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(RBM5)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 88.71199799 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 91.08599854 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 124.28800201 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 126.66200256 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 186.64199829 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 189.01600647 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 223.49000549 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(RN)1(A)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 81.55400085 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 83.9280014 12.82499981 Tm [(bi)-1(nd)-1(in)-1(g)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 115.7559967 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 118.12999725 12.82499981 Tm [(moti)-1(f)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 141.18600464 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 143.55999756 12.82499981 Tm [(protein)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 174.94200134 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 177.31599426 12.82499981 Tm [(5;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 185.44700623 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 187.82099915 12.82499981 Tm [(G15;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 207.897995 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 210.27200317 12.82499981 Tm [(H37;)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 230.26699829 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 232.64100647 12.82499981 Tm [(RMB5;)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 261.1619873 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 263.53601074 12.82499981 Tm [(LUCA1)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 291.68301392 12.82499981 Tm [(5)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 297.00500488 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <</MCID 52 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001A>-4<001B>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 21.08399963 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 242.43400574 cm /P <</MCID 58 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 270.37298584 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 27.9109993 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 30.28499985 12.55799961 Tm [(protein)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 61.66699982 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 64.04100037 12.55799961 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 125.62599945 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 128 12.55799961 Tm [(to)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 137.05400085 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 139.42799377 12.55799961 Tm [(N)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 146.20599365 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 148.58000183 12.55799961 Tm [(ter)1(min)-1(al)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 184.73500061 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 187.10899353 12.55799961 Tm [(250)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 203.07400513 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 205.44799805 12.55799961 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 232.32899475 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 234.70300293 12.55799961 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 256.20498657 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 258.57901001 12.55799961 Tm [(of)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 267.32000732 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 269.69400024 12.55799961 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 299.66101074 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 302.03500366 12.55799961 Tm [(RBM5)] TJ ET EMC /P <</MCID 82 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 327.74700928 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 299.31201172 cm /P <</MCID 83 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 327.25100708 cm /P <</Lang (zh-CN) /MCID 84 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001C>-4<001D>-4<001E>-4<001F>] TJ ET EMC /P <</MCID 85 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 42.16799927 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 355.19000244 cm /P <</MCID 86 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 383.1289978 cm q /GS2 gs 1 g 0.375 0.75 m 114.67500305 0.75 l 114.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 115.67500305 -0.25 l 115.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 87 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 90 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 115.42500305 16.35000038 l h f* Q q 1 0 0 1 115.05000305 0 cm -0.625 -0.25 m 312.125 -0.25 l 312.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 91 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(RNA)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 19.52499962 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 24.02499962 11.72200012 Tm [(binding)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 57.16899872 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 61.66899872 11.72200012 Tm [(mot)1(if)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 84.69200134 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 89.19200134 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 120.49900055 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 124.99900055 11.72200012 Tm [(5)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 130.2769928 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 114.67500305 0.75 l 114.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 115.67500305 -0.25 l 115.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 101 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 102 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 115.42500305 16.35000038 l h f* Q q 1 0 0 1 115.05000305 0 cm -0.625 -0.25 m 312.125 -0.25 l 312.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 103 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(G15)-1(;)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 19.41500092 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 23.91500092 11.72200012 Tm [(H3)-1(7;)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 43.59799957 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 48.09799957 11.72200012 Tm [(RMB5)-1(;)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 75.85800171 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 80.35800171 11.72200012 Tm [(LUCA)1(1)-1(5)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 114.60500336 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 114.67500305 0.75 l 114.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 115.67500305 -0.25 l 115.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 111 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 112 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 115.42500305 16.35000038 l h f* Q q 1 0 0 1 115.05000305 0 cm -0.625 -0.25 m 312.125 -0.25 l 312.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 113 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(P52)-1(75)-1(6)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 31.89599991 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 114.67500305 0.75 l 114.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 115.67500305 -0.25 l 115.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 115 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 118 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 115.42500305 16.35000038 l h f* Q q 1 0 0 1 115.05000305 0 cm -0.625 -0.25 m 312.125 -0.25 l 312.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 119 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(02)-1(95)-1(7)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 114.67500305 0.75 l 114.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 115.67500305 -0.25 l 115.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 121 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 122 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 115.42500305 16.35000038 l h f* Q q 1 0 0 1 115.05000305 0 cm -0.625 -0.25 m 312.125 -0.25 l 312.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 123 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 114.67500305 0.75 l 114.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 115.67500305 -0.25 l 115.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 139 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 142 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 115.42500305 16.35000038 l h f* Q q 1 0 0 1 115.05000305 0 cm -0.625 -0.25 m 312.125 -0.25 l 312.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 143 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 114.67500305 0.75 l 114.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 115.67500305 -0.25 l 115.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 147 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 148 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 115.42500305 16.35000038 l h f* Q q 1 0 0 1 115.05000305 0 cm -0.625 -0.25 m 312.125 -0.25 l 312.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 149 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 114.67500305 0.75 l 114.67500305 109.94999695 l 0.375 109.94999695 l h f* Q q -0.625 -0.25 m 115.67500305 -0.25 l 115.67500305 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 161 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 58.52199936 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 162 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 58.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.42500305 0.75 m 426.17498779 0.75 l 426.17498779 109.94999695 l 115.42500305 109.94999695 l h f* Q q 1 0 0 1 115.05000305 0 cm -0.625 -0.25 m 312.125 -0.25 l 312.125 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 163 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 54.3390007 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 58.8390007 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 63.81399918 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 68.31400299 11.72200012 Tm [(candidat)1(e)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 110.69000244 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 115.19000244 11.72200012 Tm [(tumor)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 141.67999268 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 146.17999268 11.72200012 Tm [(supp)1(re)-1(ss)1(or)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 193.42100525 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 197.92100525 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 219.43699646 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 223.93699646 11.72200012 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 249.03399658 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 253.53399658 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 289.45098877 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 293.95098877 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 298.92599487 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(nuc)-1(lear)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 31.51799965 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 36.01800156 27.3220005 Tm [(RNA)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 55.54299927 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 60.04299927 27.3220005 Tm [(binding)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 93.18699646 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 97.68699646 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 128.9940033 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 133.4940033 27.3220005 Tm [(th)1(at)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 150.71600342 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 155.21600342 27.3220005 Tm [(is)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 161.7769928 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 166.2769928 27.3220005 Tm [(a)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 171.2519989 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 175.7519989 27.3220005 Tm [(component)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 225.44099426 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 229.94099426 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 238.78300476 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 243.28300476 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 257.28399658 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 261.78399658 27.3220005 Tm [(splice)-1(o)1(so)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(me)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 13.53999996 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 18.04000092 42.92200089 Tm [(A)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 24.37299919 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 28.87299919 42.92200089 Tm [(complex.)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 67.51899719 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 72.01899719 42.92200089 Tm [(The)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 87.8259964 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 92.3259964 42.92200089 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 129.83299255 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 134.33299255 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 165.63999939 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 170.13999939 42.92200089 Tm [(plays)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 192.18699646 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 196.68699646 42.92200089 Tm [(a)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 201.66200256 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 206.16200256 42.92200089 Tm [(role)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 222.82200623 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 227.32200623 42.92200089 Tm [(in)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 235.26300049 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 239.76300049 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 253.76400757 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 258.26400757 42.92200089 Tm [(induc)-1(t)1(ion)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 299.03601074 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 8.84200001 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 13.34200001 58.52199936 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 27.75200081 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 32.2519989 58.52199936 Tm [(cy)-1(cle)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 53.54399872 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 58.04399872 58.52199936 Tm [(arr)1(e)-1(st)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 82.51699829 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 87.01699829 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 103.29399872 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 107.79399872 58.52199936 Tm [(ap)1(opt)1(osis)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 149.78799438 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 154.28799438 58.52199936 Tm [(th)1(rough)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 189.18499756 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 193.68499756 58.52199936 Tm [(pre-mR)1(NA)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 239.82800293 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 244.32800293 58.52199936 Tm [(splicin)-1(g)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 277.24301147 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 281.74301147 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 290.58499146 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 295.08499146 58.52199936 Tm [(m)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ultiple)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 26.93799973 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 31.43799973 74.12200165 Tm [(ta)1(rget)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 57.41799927 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 61.91799927 74.12200165 Tm [(gene)-1(s)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 87.59999847 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 92.09999847 74.12200165 Tm [(inc)-1(luding)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 131.94999695 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 136.44999695 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 150.45100403 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 154.95100403 74.12200165 Tm [(tumor)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 181.44099426 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 185.94099426 74.12200165 Tm [(supp)1(re)-1(ss)1(or)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 233.18200684 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 237.68200684 74.12200165 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 268.98901367 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 273.48901367 74.12200165 Tm [(p53)-1(.)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 291.95901489 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 296.45901489 74.12200165 Tm [(T)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(his)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 12.10299969 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 16.60300064 89.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 38.11899948 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 42.61899948 89.72200012 Tm [(is)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 49.18000031 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 53.68000031 89.72200012 Tm [(located)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 85.50099945 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 90.00099945 89.72200012 Tm [(wit)1(hin)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 116.33699799 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 120.83699799 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 134.83799744 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 139.33799744 89.72200012 Tm [(tumor)] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 165.82800293 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 170.32800293 89.72200012 Tm [(supp)1(re)-1(ss)1(or)] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 217.56900024 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 222.06900024 89.72200012 Tm [(region)] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 250.03100586 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 254.53100586 89.72200012 Tm [(3p2)-1(1.3,)] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 285.72299194 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 290 >> BDC BT 1 0 0 -1 290.22299194 89.72200012 Tm [(an)] TJ ET EMC /P <</MCID 291 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(d)] TJ ET EMC /P <</MCID 292 >> BDC BT 1 0 0 -1 5.75699997 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 293 >> BDC BT 1 0 0 -1 10.25699997 105.3219986 Tm [(may)] TJ ET EMC /P <</MCID 294 >> BDC BT 1 0 0 -1 28.4279995 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 295 >> BDC BT 1 0 0 -1 32.9280014 105.3219986 Tm [(play)] TJ ET EMC /P <</MCID 296 >> BDC BT 1 0 0 -1 50.80899811 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 297 >> BDC BT 1 0 0 -1 55.30899811 105.3219986 Tm [(a)] TJ ET EMC /P <</MCID 298 >> BDC BT 1 0 0 -1 60.2840004 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 299 >> BDC BT 1 0 0 -1 64.78399658 105.3219986 Tm [(role)] TJ ET EMC /P <</MCID 300 >> BDC BT 1 0 0 -1 81.44400024 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 301 >> BDC BT 1 0 0 -1 85.94400024 105.3219986 Tm [(in)] TJ ET EMC /P <</MCID 302 >> BDC BT 1 0 0 -1 93.88500214 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 303 >> BDC BT 1 0 0 -1 98.38500214 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 304 >> BDC BT 1 0 0 -1 112.38600159 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 305 >> BDC BT 1 0 0 -1 116.88600159 105.3219986 Tm [(inhibitio)1(n)] TJ ET EMC /P <</MCID 306 >> BDC BT 1 0 0 -1 157.92199707 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 307 >> BDC BT 1 0 0 -1 162.42199707 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 308 >> BDC BT 1 0 0 -1 171.26400757 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 309 >> BDC BT 1 0 0 -1 175.76400757 105.3219986 Tm [(tumor)] TJ ET EMC /P <</MCID 310 >> BDC BT 1 0 0 -1 202.2539978 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 311 >> BDC BT 1 0 0 -1 206.7539978 105.3219986 Tm [(tr)1(ansfor)1(m)-1(a)1(tion)] TJ ET EMC /P <</MCID 312 >> BDC BT 1 0 0 -1 270.93200684 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 313 >> BDC BT 1 0 0 -1 275.43200684 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 314 >> BDC BT 1 0 0 -1 291.70901489 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 315 >> BDC BT 1 0 0 -1 296.20901489 105.3219986 Tm [(p)] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.05000305 0.75 m 115.05000305 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.05000305 17.10000038 m 115.05000305 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.05000305 33.45000076 m 115.05000305 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.05000305 49.80000305 m 115.05000305 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.05000305 66.15000153 m 115.05000305 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.05000305 82.5 m 115.05000305 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.05000305 98.84999847 m 115.05000305 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.05000305 115.19999695 m 115.05000305 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.54998779 0.75 m 426.54998779 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17498779 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 426.17498779 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 224.7749939 m 426.92498779 224.7749939 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 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