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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1499939 0 0 -90.05000305 0 90.05000305 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 207.6499939 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABC 22 Tf 1 0 0 -1 99.44200134 41.61599731 Tm 2 Tr /GS2 gs 0 g 0.62857145 w 0 G [<0003>-4<0004>] TJ ET EMC /P <> BDC BT /FAAABI 22 Tf 1 0 0 -1 149.11799622 41.61599731 Tm 0 Tr [(IL)1(12A)] TJ ET EMC /P <> BDC BT /FAAABC 22 Tf 1 0 0 -1 205.41799927 41.61599731 Tm 2 Tr [<0005>-4<0006>-4<0007>-4<0004>-4<0008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 315.85800171 41.61599731 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 64.73899841 cm /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 86.625 12.82499981 Tm [(IL12A)] TJ ET EMC /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 113.02899933 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 165.52900696 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.77900696 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 98.27799988 cm /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(IL12A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.51200104 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.88600159 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.53599548 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.91000366 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.46899414 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.84300232 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.63900757 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 131.81700134 cm /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000B000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(P3)1(5;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.8769989 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.25099945 12.82499981 Tm [(CL)-1(MF;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.875 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.24900055 12.82499981 Tm [(NFSK;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.94000244 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.31399536 12.82499981 Tm [(NK)1(S)-1(F1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.32699585 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.70100403 12.82499981 Tm [(IL-)-1(1)1(2A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.69400024 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 165.35600281 cm /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 198.89500427 cm /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0015000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 232.43400574 cm /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 265.97299194 cm /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(IL12A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.77899933 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 299.51199341 cm /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E001F00200021000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 333.05099487 cm /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0022>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0023>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0024000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 366.58999634 cm /P <> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700120025000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 400.1289978 m 416.75 400.1289978 l 416.75 431.32901001 l -1.45000005 431.32901001 l h f* Q q 1 0 0 1 0 400.1289978 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 431.32901001 cm /P <> BDC BT 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 459.26800537 cm q /GS2 gs 1 g 0.375 0.75 m 113.92500305 0.75 l 113.92500305 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 114.92500305 -0.25 l 114.92500305 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 114.67500305 0.75 m 422.375 0.75 l 422.375 156.75 l 114.67500305 156.75 l h f* Q q 1 0 0 1 114.30000305 0 cm -0.625 -0.25 m 309.07501221 -0.25 l 309.07501221 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(subunit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.97000122 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.47000122 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.31199646 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.81199646 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.78700256 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.28700256 11.72200012 Tm [(cy)-1(t)1(oki)-1(ne)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.58599854 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.08599854 11.72200012 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.30799866 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.80799866 11.72200012 Tm [(acts)] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.81500244 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.31500244 11.72200012 Tm [(on)] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.58299255 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.08300781 11.72200012 Tm [(T)] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.24200439 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.74200439 11.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 283.01901245 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 287.51901245 11.72200012 Tm [(na)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(tura)1(l)] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.70499992 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.20499992 27.3220005 Tm [(ki)-1(ller)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.83300018 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.33300018 27.3220005 Tm [(ce)-1(lls,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.07499695 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.57499695 27.3220005 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.85199738 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.35199738 27.3220005 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.03399658 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.53399658 27.3220005 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.50900269 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.00900269 27.3220005 Tm [(bro)1(ad)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.64700317 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.14700317 27.3220005 Tm [(arr)1(ay)] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.73300171 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.23300171 27.3220005 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.07499695 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.57499695 27.3220005 Tm [(biolo)1(gic)-1(a)1(l)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.59100342 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.09100342 27.3220005 Tm [(activit)1(i)-1(es.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 279.63299561 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 284.13299561 27.3220005 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 299.94000244 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(cy)-1(t)1(oki)-1(ne)] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.29899979 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.79899979 42.92200089 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.36000061 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.86000061 42.92200089 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.83499908 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.33499908 42.92200089 Tm [(disulfid)1(e)-1(-)1(l)-1(inke)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.96499634 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.46499634 42.92200089 Tm [(heterod)1(ime)-1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.85899353 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.35899353 42.92200089 Tm [(composed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.52600098 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.02600098 42.92200089 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.86799622 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.36799622 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.36898804 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.86898804 42.92200089 Tm [(35)-1(-)1(k)-1(D)] TJ ET EMC /P <> BDC BT 1 0 0 -1 298.07400513 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(subunit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.29999924 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.79999924 58.52199936 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.30699921 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.80699921 58.52199936 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.31900024 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.81900024 58.52199936 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.27500153 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.77500153 58.52199936 Tm [(gene)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.45700073 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.95700073 58.52199936 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.23399353 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.73399353 58.52199936 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.70899963 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.20899963 58.52199936 Tm [(40)-1(-)1(k)-1(D)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.41400146 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.91400146 58.52199936 Tm [(subunit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.21400452 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.71400452 58.52199936 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.93600464 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.43600464 58.52199936 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.99700928 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 272.49700928 58.52199936 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 277.47198486 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 281.97198486 58.52199936 Tm [(me)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(mber)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.72400093 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.22400093 74.12200165 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.06600189 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.56600189 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.56700134 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.06700134 74.12200165 Tm [(cy)-1(t)1(oki)-1(ne)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.36599731 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.86599731 74.12200165 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.28799438 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.78799438 74.12200165 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.03599548 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.53599548 74.12200165 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.79800415 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.29800415 74.12200165 Tm [(cy)-1(t)1(oki)-1(ne)] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.59700012 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.09700012 74.12200165 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.65800476 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.15800476 74.12200165 Tm [(required)] TJ ET EMC /P <> BDC BT 1 0 0 -1 283.69900513 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.19900513 74.12200165 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 300.47698975 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.0010004 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.50099945 89.72200012 Tm [(T-ce)-1(ll-independent)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.8239975 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.3239975 89.72200012 Tm [(induc)-1(t)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.09599304 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.59599304 89.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.43800354 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.93800354 89.72200012 Tm [(interferon)] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.70599365 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.20599365 89.72200012 Tm [(\(IFN\)-g)1(amma,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.59399414 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 275.09399414 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 291.3710022 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 295.8710022 89.72200012 Tm [(i)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 4.16599989 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.66600037 105.3219986 Tm [(impor)1(tant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.6269989 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.1269989 105.3219986 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.40499878 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.90499878 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.90599823 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.40599823 105.3219986 Tm [(dif)1(fe)-1(r)1(e)-1(nt)1(i)-1(a)1(tion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.73199463 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.23199463 105.3219986 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.07400513 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.57400513 105.3219986 Tm [(bo)1(th)] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.93800354 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.43800354 105.3219986 Tm [(Th1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.41700745 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.91700745 105.3219986 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.19400024 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.69400024 105.3219986 Tm [(Th2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.67300415 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.17300415 105.3219986 Tm [(ce)-1(lls.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 277.91500854 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 282.41500854 105.3219986 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 298.22198486 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(responses)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.1629982 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.6629982 120.92199707 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.50500107 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.00500107 120.92199707 Tm [(lymphocytes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.51000214 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.01000214 120.92199707 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.08500671 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.58500671 120.92199707 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.04100037 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.54100037 120.92199707 Tm [(cy)-1(t)1(oki)-1(ne)] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.83999634 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.33999634 120.92199707 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.85800171 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.35800171 120.92199707 Tm [(mediat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.24000549 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.73999023 120.92199707 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 268.25201416 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 272.75201416 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 286.75299072 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 291.25299072 120.92199707 Tm [(ac)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(tiva)1(tor)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.95800018 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.45800018 136.52200317 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.29999924 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.79999924 136.52200317 Tm [(tr)1(ansc)-1(rip)1(tion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.38400269 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.88400269 136.52200317 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.19099426 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.69099426 136.52200317 Tm [(STAT4)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.98100281 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.48100281 136.52200317 Tm [(Nitr)1(i)-1(c)] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.89100647 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.39100647 136.52200317 Tm [(oxid)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.93299866 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.43299866 136.52200317 Tm [(syntha)1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 268.04998779 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 272.54998779 136.52200317 Tm [(2A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 284.16000366 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.66000366 136.52200317 Tm [(\(N)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(OS2)-1(A)1(/NOS2)-1(\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.11399841 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.61399841 152.12199402 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.17500305 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.67500305 152.12199402 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.36499786 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.86499786 152.12199402 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.94000244 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.44000244 152.12199402 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.29399872 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.79400635 152.12199402 Tm [(required)] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.33500671 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.83500671 152.12199402 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.11300659 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.61300659 152.12199402 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.61399841 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.11399841 152.12199402 Tm [(signaling)] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.04499817 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.54499817 152.12199402 Tm [(pro)1(c)-1(ess)] TJ ET EMC /P <> BDC BT 1 0 0 -1 283.40301514 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 287.90301514 152.12199402 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 296.74499512 152.12199402 Tm [( )] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 114.30000305 0.75 m 114.30000305 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.75 0.75 m 422.75 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.125 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 157.125 m 423.125 157.125 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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