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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 93.58699799 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 143.26300049 23.67700005 Tm 0 Tr [(NR4A)1(2)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 211.27200317 23.67700005 Tm 2 Tr [<0005>-4<0006>-4<0007>-4<0004>-4<0008>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 321.71200562 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 76.125 12.82499981 Tm [(NR)1(4A2)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 107.94799805 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 160.44799805 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.69799805 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(N)1(R4A2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.93099976 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.30500031 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.95500183 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.32899475 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.88800049 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.26199341 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.05799866 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000F000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(NR)1(4A2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.19799805 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(NOT;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.65599823 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.02999878 12.82499981 Tm [(RN)1(R1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.34200287 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.71600342 12.82499981 Tm [(HZF)-1(-3;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.34500122 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.71899414 12.82499981 Tm [(NU)1(RR1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.76699829 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.14100647 12.82499981 Tm [(TINU)1(R)] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.1190033 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0012000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001300140015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<00160017>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0018>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0019000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B001C0010000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001D0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E001F00200021000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.96800232 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.34199524 12.82499981 Tm [(Rat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.58999634 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002200230024000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<00060007001C0025000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC q /GS2 gs 1 g 0 24.53299904 m 42 24.53299904 l 42 42.54399872 l 0 42.54399872 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 38.11399841 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 38.11399841 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 413.39001465 cm q /GS2 gs 1 g 0.375 0.75 m 154.42500305 0.75 l 154.42500305 141.1499939 l 0.375 141.1499939 l h f* Q q -0.625 -0.25 m 155.42500305 -0.25 l 155.42500305 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 74.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 57.29199982 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 155.17500305 0.75 m 422.42498779 0.75 l 422.42498779 141.1499939 l 155.17500305 141.1499939 l h f* Q q 1 0 0 1 154.80000305 0 cm -0.625 -0.25 m 268.625 -0.25 l 268.625 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(st)1(e)-1(ro)1(i)-1(d)1(-t)1(hyroid)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.07400513 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.57400513 11.72200012 Tm [(ho)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(mone-retinoid)] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.4109993 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.91100311 27.3220005 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.33300018 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.83300018 27.3220005 Tm [(superfa)1(mi)-1(ly.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.08399963 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.58399963 27.3220005 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.39100647 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.89100647 27.3220005 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.397995 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.897995 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.20498657 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(may)] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.17099953 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.67099953 42.92200089 Tm [(act)] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.51200104 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.01200104 42.92200089 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.15299988 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.65299988 42.92200089 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.62799835 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.12799835 42.92200089 Tm [(tr)1(ansc)-1(rip)1(tion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.71199799 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.21199799 42.92200089 Tm [(fa)1(c)-1(t)1(or.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.4980011 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.9980011 42.92200089 Tm [(Mutat)1(ions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.84700012 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.34700012 42.92200089 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.28799438 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.78799438 42.92200089 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.2440033 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.7440033 42.92200089 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.26000977 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ha)1(ve)] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.34700012 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.84700012 58.52199936 Tm [(been)] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.35400009 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.85400009 58.52199936 Tm [(asso)1(c)-1(iat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.98100281 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.48100281 58.52199936 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.8769989 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.3769989 58.52199936 Tm [(diso)1(rders)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.31900024 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.81900024 58.52199936 Tm [(related)] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.94799805 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.44799805 58.52199936 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.522995 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.022995 58.52199936 Tm [(do)1(pamine)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(rg)1(i)-1(c)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.10199928 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.60199928 74.12200165 Tm [(dysfunction,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.19599915 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.69599915 74.12200165 Tm [(inc)-1(luding)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.54599762 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.04599762 74.12200165 Tm [(Par)1(k)-1(inson)] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.23800659 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.73800659 74.12200165 Tm [(disease,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.57600403 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.07600403 74.12200165 Tm [(schizop)1(hern)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ia,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.53600025 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.03600025 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.31299973 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.81299973 89.72200012 Tm [(manic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.67499924 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.17500305 89.72200012 Tm [(depression.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.48999786 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.98999786 89.72200012 Tm [(Misregulatio)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.57499695 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.07499695 89.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.91700745 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.41700745 89.72200012 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.8730011 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.3730011 89.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.88900757 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.38900757 89.72200012 Tm [(ma)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 4.76399994 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.26399994 105.3219986 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.11800003 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.61800003 105.3219986 Tm [(asso)1(c)-1(iat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.74500275 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.24500275 105.3219986 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.64099884 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.14099884 105.3219986 Tm [(rheumat)1(oid)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.40600586 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.90600586 105.3219986 Tm [(art)1(hrit)1(is.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.12399292 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.62399292 105.3219986 Tm [(Alt)1(e)-1(rna)1(tivel)-1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.50500488 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.00500488 105.3219986 Tm [(sp)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(lic)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.16699982 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.66699982 120.92199707 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.58899689 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.08899689 120.92199707 Tm [(var)1(i)-1(a)1(n)-1(t)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.65899658 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.15899658 120.92199707 Tm [(ha)1(ve)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.5059967 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.0059967 120.92199707 Tm [(been)] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.51300049 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.01300049 120.92199707 Tm [(described,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.16499329 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.66499329 120.92199707 Tm [(but)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.31199646 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.81199646 120.92199707 Tm [(th)1(e)-1(ir)] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.64500427 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.14500427 120.92199707 Tm [(bi)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(olog)1(ic)-1(al)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.8730011 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.3730011 136.52200317 Tm [(validit)1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.12999725 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.62999725 136.52200317 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.31199646 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.81199646 136.52200317 Tm [(not)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.43299866 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.93299866 136.52200317 Tm [(been)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.44000244 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.94000244 136.52200317 Tm [(determine)-1(d)1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.10299683 136.52200317 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 141.1499939 cm q /GS2 gs 1 g 0.375 0.75 m 154.42500305 0.75 l 154.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 155.42500305 -0.25 l 155.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 155.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 155.17500305 16.35000038 l h f* Q q 1 0 0 1 154.80000305 0 cm -0.625 -0.25 m 268.625 -0.25 l 268.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ELISA,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.90600014 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.40600014 11.72200012 Tm [(IHC)] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.03300095 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 157.5 cm q /GS2 gs 1 g 0.375 0.75 m 154.42500305 0.75 l 154.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 155.42500305 -0.25 l 155.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 155.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 155.17500305 16.35000038 l h f* Q q 1 0 0 1 154.80000305 0 cm -0.625 -0.25 m 268.625 -0.25 l 268.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(NR4A2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.08099937 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 173.8500061 cm q /GS2 gs 1 g 0.375 0.75 m 154.42500305 0.75 l 154.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 155.42500305 -0.25 l 155.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunogen:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 155.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 155.17500305 16.35000038 l h f* Q q 1 0 0 1 154.80000305 0 cm -0.625 -0.25 m 268.625 -0.25 l 268.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Fusion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.15600014 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.65599823 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.96300125 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.46299744 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.30500031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.80500031 11.72200012 Tm [(human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.84600067 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.34600067 11.72200012 Tm [(NR4A2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.42700195 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 190.19999695 cm q /GS2 gs 1 g 0.375 0.75 m 154.42500305 0.75 l 154.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 155.42500305 -0.25 l 155.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 155.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 155.17500305 16.35000038 l h f* Q q 1 0 0 1 154.80000305 0 cm -0.625 -0.25 m 268.625 -0.25 l 268.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(nuc)-1(lear)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.51799965 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.01800156 11.72200012 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.44000244 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.94000244 11.72200012 Tm [(subf)1(amily)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.48200226 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.98200226 11.72200012 Tm [(4,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.42599487 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.92599487 11.72200012 Tm [(gr)1(oup)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.13499451 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.63499451 11.72200012 Tm [(A,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.13400269 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.63400269 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.897995 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.397995 11.72200012 Tm [(2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.67599487 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 206.55001831 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 154.80000305 0.75 m 154.80000305 141.1499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 154.80000305 141.8999939 m 154.80000305 157.5 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 154.80000305 158.25 m 154.80000305 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 154.80000305 174.6000061 m 154.80000305 190.20001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 154.80000305 190.95001221 m 154.80000305 206.55001831 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 206.55001831 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 141.5249939 m 422.42498779 141.5249939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.875 m 422.42498779 157.875 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 174.2250061 m 422.42498779 174.2250061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 190.57501221 m 422.42498779 190.57501221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 206.92501831 m 423.17498779 206.92501831 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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