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[<0009000A000B000C000D>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 86.625 12.82499981 Tm [(IL10RA)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 118.73000336 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 171.22999573 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 176.47999573 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(IL10RA)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 113.21299744 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 115.58699799 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 141.23699951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 143.61099243 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 187.16999817 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 189.54400635 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 227.33999634 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CD210,)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 93.64399719 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 96.01799774 12.82499981 Tm [(IL10R,)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 122.04199982 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 124.41600037 12.82499981 Tm [(CD210a,)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 160.08900452 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 162.46299744 12.82499981 Tm [(CDW210A)1(,)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 208.52400208 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 210.897995 12.82499981 Tm [(HIL-)-1(1)1(0R,)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 246.67900085 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 249.05299377 12.82499981 Tm [(IL-)-1(1)1(0R1)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 280.99398804 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 37 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 38 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 39 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0010000D>] TJ ET EMC /P <</MCID 40 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(IL10RA)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 92.48000336 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0012000D>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001300140015>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<00160017>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0018>] TJ ET EMC /P <</MCID 52 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0019000D>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B001C000F000D>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001D0004>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 63 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 64 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002200230024000D>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 72 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<00060007001C0025>] TJ ET EMC /P <</MCID 73 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 78 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 79 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 80 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 81 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 144.67500305 0.75 l 144.67500305 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 145.67500305 -0.25 l 145.67500305 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 82 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 83 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 145.42500305 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 145.42500305 172.3500061 l h f* Q q 1 0 0 1 145.05000305 0 cm -0.625 -0.25 m 278.375 -0.25 l 278.375 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 84 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 175.14100647 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 179.64100647 11.72200012 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 216.06300354 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 220.56300354 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 232.84100342 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 237.34100342 11.72200012 Tm [(interle)-1(u)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ki)-1(n)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 12.8409996 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 17.3409996 27.3220005 Tm [(10)-1(.)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 30.06299973 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 34.56299973 27.3220005 Tm [(This)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 51.82500076 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 56.32500076 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 87.63200378 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 92.13200378 27.3220005 Tm [(is)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 98.69300079 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 103.19300079 27.3220005 Tm [(st)1(ruc)-1(tura)1(ll)-1(y)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 151.07099915 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 155.57099915 27.3220005 Tm [(related)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 185.69999695 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 190.19999695 27.3220005 Tm [(to)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 199.2749939 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 203.7749939 27.3220005 Tm [(interferon)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 246.54299927 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 251.04299927 27.3220005 Tm [(rec)-1(e)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(pt)1(ors.)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 24.59199905 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 29.09199905 42.92200089 Tm [(It)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 35.0909996 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 39.5909996 42.92200089 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 54.27299881 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 58.77299881 42.92200089 Tm [(been)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 80.27999878 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 84.77999878 42.92200089 Tm [(sho)1(wn)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 112.86100006 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 117.36100006 42.92200089 Tm [(to)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 126.43599701 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 130.93600464 42.92200089 Tm [(mediat)1(e)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 166.06100464 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 170.56100464 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 184.56199646 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 189.06199646 42.92200089 Tm [(immun)-1(o)1(suppressi)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ve)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 9.83100033 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 14.33100033 58.52199936 Tm [(signal)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 39.56399918 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 44.06399918 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 52.90599823 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 57.40599823 58.52199936 Tm [(interle)-1(ukin)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 103.1309967 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 107.6309967 58.52199936 Tm [(10)-1(,)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 120.35299683 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 124.85299683 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 141.13000488 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 145.63000488 58.52199936 Tm [(th)1(us)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 164.23599243 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 168.73599243 58.52199936 Tm [(inhibits)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 200.27600098 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 204.77600098 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 218.7769928 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 223.2769928 58.52199936 Tm [(synthesis)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 262.48098755 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 8.84200001 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 13.34200001 74.12200165 Tm [(pro)1(in)-1(f)1(lammat)1(ory)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 85.79499817 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 90.29499817 74.12200165 Tm [(cy)-1(t)1(oki)-1(nes.)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 132.92599487 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 137.42599487 74.12200165 Tm [(This)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 154.68800354 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 159.18800354 74.12200165 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 195.61000061 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 200.11000061 74.12200165 Tm [(is)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 206.67100525 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 211.17100525 74.12200165 Tm [(repor)1(ted)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 248.83700562 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 253.33700562 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 262.4119873 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(pro)1(mote)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 37.52099991 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 42.02099991 89.72200012 Tm [(survival)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 74.38200378 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 78.88200378 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 87.72399902 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 92.22399902 89.72200012 Tm [(pro)1(geni)-1(t)1(or)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 138.44599915 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 142.94599915 89.72200012 Tm [(mye)-1(loid)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 177.51800537 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 182.01800537 89.72200012 Tm [(ce)-1(lls)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 200.59399414 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 205.09399414 89.72200012 Tm [(th)1(rough)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 239.99099731 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 244.49099731 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 258.49200439 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 262.99200439 89.72200012 Tm [(i)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(nsuli)-1(n)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 25.59399986 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 30.09399986 105.3219986 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 66.51599884 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 71.01599884 105.3219986 Tm [(subst)1(rat)1(e)-1(-)1(2)-1(/PI)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 132.03399658 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 136.53399658 105.3219986 Tm [(3-ki)-1(nas)1(e)-1(/AK)1(T)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 193.84300232 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 198.34300232 105.3219986 Tm [(pa)1(thw)1(ay.)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 236.97099304 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 241.47099304 105.3219986 Tm [(Activa)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(tio)1(n)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 17.01600075 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 21.51600075 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 30.3579998 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 34.85800171 120.92199707 Tm [(th)1(is)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 50.31399918 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 54.81399918 120.92199707 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 91.23600006 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 95.73600006 120.92199707 Tm [(leads)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 118.13500214 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 122.63500214 120.92199707 Tm [(to)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 131.71000671 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 136.21000671 120.92199707 Tm [(tyro)1(sin)-1(e)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 170.69799805 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 175.19799805 120.92199707 Tm [(ph)1(osph)1(orylation)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 245.97200012 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 250.47200012 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 259.31399536 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 263.81399536 120.92199707 Tm [(J)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(AK)1(1)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 17.32299995 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 21.82299995 136.52200317 Tm [(and)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 38.09999847 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 42.59999847 136.52200317 Tm [(TYK2)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 64.18199921 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 68.68199921 136.52200317 Tm [(ki)-1(na)1(se)-1(s.)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 102.10199738 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 106.60199738 136.52200317 Tm [(Two)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 124.58899689 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 129.08900452 136.52200317 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 170.01100159 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 174.51100159 136.52200317 Tm [(var)1(i)-1(a)1(n)-1(t)1(s,)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 210.24699402 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 214.74699402 136.52200317 Tm [(one)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 231.1210022 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 235.6210022 136.52200317 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(-cod)1(i)-1(ng)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 33.58300018 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 38.08300018 152.12199402 Tm [(and)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 54.36000061 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 58.86000061 152.12199402 Tm [(th)1(e)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 72.86100006 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 77.36100006 152.12199402 Tm [(ot)1(her)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 100.51999664 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 105.01999664 152.12199402 Tm [(not)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 119.64099884 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 124.14099884 152.12199402 Tm [(pro)1(tein)-1(-)1(c)-1(o)1(ding,)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 191.19700623 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 195.69700623 152.12199402 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 216.04400635 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 220.54400635 152.12199402 Tm [(been)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 242.05099487 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 246.55099487 152.12199402 Tm [(fo)1(u)-1(n)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(d)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 5.75699997 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 10.25699997 167.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 22.53499985 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 27.03499985 167.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 42.49100113 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 46.99100113 167.72200012 Tm [(gene)-1(.)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 70.67299652 167.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 145.05000305 0.75 m 145.05000305 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 172.7250061 m 423.17498779 172.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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