%PDF-1.5
%ÈÈÈÈÈÈ?1 0 obj
<>
endobj
2 0 obj
<>/Metadata 79 0 R>>
endobj
3 0 obj
<>
endobj
4 0 obj
<>/ExtGState<>/XObject<>>>/Group<>/StructParents 0/Tabs/S>>
endobj
5 0 obj
<>stream
1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 269.45001221 0 0 -90.09999847 0 90.09999847 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm q 1 0 0 1 110 0 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 0 23.67700005 Tm 0 g [(Cy3)] TJ ET EMC /P <> BDC BT /FAAABE 22 Tf 1 0 0 -1 38.71500015 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 176.74299622 23.67700005 Tm 0 Tr [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.05700684 23.67700005 Tm [( )] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 212.03100586 23.67700005 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 -110 43.75799942 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -110 61.9640007 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -57.5 61.9640007 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 -47 61.9640007 Tm [(Cy3)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -28.70200348 61.9640007 Tm [<000300040005000600070008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 36.92300415 61.9640007 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.13499451 61.9640007 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.50900269 61.9640007 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 82.6780014 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000E000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.75 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Cy3-conj)-1(ugate)1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.63999939 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.01400757 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.37600708 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.75 12.82499981 Tm [(anti)-1(-rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.08799744 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.46200562 12.82499981 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.67399597 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 116.21700287 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F001000110012000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001300140003000400150007>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 126 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 149.7559967 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0016>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [<0017000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 47.25 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00180019001A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001B001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 183.29499817 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0003>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0004001D000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 47.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm [(Cy3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.67299652 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 216.83399963 m 416.75 216.83399963 l 416.75 248.03399658 l -1.45000005 248.03399658 l h f* Q q 1 0 0 1 0 216.83399963 cm /P <> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 275.97299194 cm q 1 g 0.375 0.75 m 126.67500305 0.75 l 126.67500305 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 127.67500305 -0.25 l 127.67500305 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 54.72100067 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 127.42500305 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 127.42500305 156.75 l h f* Q q 1 0 0 1 127.05000305 0 cm -0.625 -0.25 m 296.375 -0.25 l 296.375 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Immunoglob)1(u)-1(lin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.82900238 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.32900238 11.72200012 Tm [(G)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.02200317 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.52200317 11.72200012 Tm [(\(IgG)1(\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.6289978 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.1289978 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.69000244 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.19000244 11.72200012 Tm [(one)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.56399536 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.06399536 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.90600586 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.40600586 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.40699768 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.90699768 11.72200012 Tm [(most)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.58099365 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.08099365 11.72200012 Tm [(ab)1(u)-1(nd)1(ant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.52600098 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.02600098 11.72200012 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 284.49899292 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 7.94099998 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.44099998 27.3220005 Tm [(serum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.12900162 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.62900162 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.02500153 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.52500153 27.3220005 Tm [(normal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.03199768 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.53199768 27.3220005 Tm [(leve)-1(ls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.42500305 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.92500305 27.3220005 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.99699402 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.49699402 27.3220005 Tm [(8-17)] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.22399902 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.72399902 27.3220005 Tm [(mg/ml)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.58700562 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.08700562 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.02799988 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.52799988 27.3220005 Tm [(ad)1(u)-1(lt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 263.55300903 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 268.05300903 27.3220005 Tm [(bloo)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(d.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 7.92299986 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.42300034 42.92200089 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.51799965 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.01800156 42.92200089 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.57899857 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.07899857 42.92200089 Tm [(impor)1(tant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.04000092 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.54000092 42.92200089 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.81800079 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.31800079 42.92200089 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.02200317 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.52200317 42.92200089 Tm [(defense)] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.42999268 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.92999268 42.92200089 Tm [(ag)1(ainst)] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.09599304 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.59599304 42.92200089 Tm [(mic)-1(r)1(oorg)1(anisms)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.69100952 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 274.19100952 42.92200089 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.75699997 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.25699997 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.25799942 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.75799942 58.52199936 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.14099884 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.64099884 58.52199936 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.15899658 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.65899658 58.52199936 Tm [(pro)1(duc)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.2440033 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.7440033 58.52199936 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.2559967 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.7559967 58.52199936 Tm [(B)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.40299988 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.90299988 58.52199936 Tm [(lymphocytes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.40800476 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.90800476 58.52199936 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.04899597 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 238.54899597 58.52199936 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.52400208 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.02400208 58.52199936 Tm [(pa)1(rt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.53601074 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.03601074 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.87799072 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.70400047 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.20400047 74.12200165 Tm [(ad)1(apt)1(ive)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.23699951 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.73699951 74.12200165 Tm [(immun)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.19599915 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.69599915 74.12200165 Tm [(response.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.86000061 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.36000061 74.12200165 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.16700745 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.66700745 74.12200165 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.76199341 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.26199341 74.12200165 Tm [(molec)-1(ule)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.47900391 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.97900391 74.12200165 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.66099548 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.16099548 74.12200165 Tm [(tw)1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.3420105 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.8420105 74.12200165 Tm [(sep)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ara)1(te)] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.84499931 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.34499931 89.72200012 Tm [(func)-1(t)1(ions;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.41799927 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.91799927 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.99299622 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.49299622 89.72200012 Tm [(bind)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.93900299 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.43900299 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.51399994 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.01399994 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.01499939 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.51499939 89.72200012 Tm [(pa)1(tho)1(gen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.26300049 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.76300049 89.72200012 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.98500061 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.48500061 89.72200012 Tm [(eli)-1(cited)] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.5059967 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.0059967 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.00698853 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.50698853 89.72200012 Tm [(resp)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(onse)] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.54000092 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.04000092 105.3219986 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.31700134 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.81700134 105.3219986 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.89199829 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.39199829 105.3219986 Tm [(rec)-1(ruit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.17900085 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.67900085 105.3219986 Tm [(ot)1(her)] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.83799744 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.33799744 105.3219986 Tm [(ce)-1(lls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.91400146 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.41400146 105.3219986 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.69099426 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.19099426 105.3219986 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.57400513 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.07400513 105.3219986 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.14900208 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.64900208 105.3219986 Tm [(dest)1(roy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.95300293 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.45300293 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 275.45401001 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 279.95401001 105.3219986 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(ntigen.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.87000084 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.36999893 120.92199707 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.17699814 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.67699814 120.92199707 Tm [(var)1(i)-1(a)1(bility)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.23200226 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.73200226 120.92199707 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.5739975 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.0739975 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.07499695 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.57499695 120.92199707 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.66999817 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.16999817 120.92199707 Tm [(po)1(ol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.7559967 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.2559967 120.92199707 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.81700134 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.31700134 120.92199707 Tm [(gene)-1(r)1(ated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.46000671 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.96000671 120.92199707 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.47200012 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.97200012 120.92199707 Tm [(soma)1(tic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 284.5289917 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(rec)-1(o)1(mbination)] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.88999939 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.38999939 136.52200317 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.66699982 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.16699982 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.16799927 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.66799927 136.52200317 Tm [(number)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.48399353 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.98399353 136.52200317 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.82600403 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.32600403 136.52200317 Tm [(speci)-1(f)1(ic)-1(it)1(i)-1(es)] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.69900513 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.19900513 136.52200317 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.13999939 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.63999939 136.52200317 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.16099548 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.66099548 136.52200317 Tm [(individual)] TJ ET EMC /P <> BDC BT 1 0 0 -1 281.54501343 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.32800007 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.82800007 152.12199402 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.8029995 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.3029995 152.12199402 Tm [(given)] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.83100128 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.33100128 152.12199402 Tm [(time)] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.6190033 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.1190033 152.12199402 Tm [(po)1(i)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.88300323 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.38300323 152.12199402 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.94400024 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.44400024 152.12199402 Tm [(estimat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.08900452 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.58900452 152.12199402 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.66400146 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.16400146 152.12199402 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.01800537 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.51800537 152.12199402 Tm [(10)-1(11)] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.6289978 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.1289978 152.12199402 Tm [(var)1(i)-1(a)1(n)-1(t)1(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.86500549 152.12199402 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 156.75 cm q 1 g 0.375 0.75 m 126.67500305 0.75 l 126.67500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 127.67500305 -0.25 l 127.67500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 19.52199936 Tm 0.13333334 g [(Applic)1(ations)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 56.50899887 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 127.42500305 0.75 m 422.42498779 0.75 l 422.42498779 31.95000076 l 127.42500305 31.95000076 l h f* Q q 1 0 0 1 127.05000305 0 cm -0.625 -0.25 m 296.375 -0.25 l 296.375 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(1/)-1(20)-1(-)1(1)-1(00)] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.40599823 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.90599823 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.18399811 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.68399811 11.72200012 Tm [(FCM)] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.27899933 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.77899933 11.72200012 Tm [(1/)-1(20)-1(-)1(2)-1(00)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.18499756 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.68499756 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.96299744 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.46299744 11.72200012 Tm [(Immunohist)1(oc)-1(h)1(e)-1(mist)1(ry/)-1(cytoche)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(mistr)1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.54700089 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 188.69999695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 127.05000305 0.75 m 127.05000305 156.75 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 127.05000305 157.5 m 127.05000305 188.69999695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 188.69999695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.125 m 422.42498779 157.125 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 189.07499695 m 423.17498779 189.07499695 l S Q Q q 1 0 0 1 0 465.42300415 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 493.36199951 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 521.30102539 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 549.23999023 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 577.17901611 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 605.11798096 cm Q Q 1 0 0 -1 0 841.90002441 cm
endstream
endobj
6 0 obj
<>stream
ºÝºÝÈÈÔÚÏßÊÓÆµÃâ·Ñ
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Îı¾Á´>
<Îı¾Á´>
<Îı¾Á´>
<Îı¾Á´>
<Îı¾Á´>
<Îı¾Á´>