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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 269.45001221 0 0 -90.09999847 0 90.09999847 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 104.1210022 23.67700005 Tm 0 g [(Cy3)] TJ ET EMC /P <> BDC BT /FAAABE 22 Tf 1 0 0 -1 142.83599854 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 280.86401367 23.67700005 Tm 0 Tr [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 311.17800903 23.67700005 Tm /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.75 12.82499981 Tm [(Cy3)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 76.04799652 12.82499981 Tm [<000300040005000600070008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 141.67300415 12.82499981 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.88499451 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.25900269 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Cy3-conj)-1(ugate)1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.63999939 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.01400757 12.82499981 Tm [(Goat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.72200012 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.09599304 12.82499981 Tm [(anti)-1(-chi)-1(ck)1(en)] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.10400391 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.47799683 12.82499981 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.69000244 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F001000110012000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001300140003000400150007>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 126 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0016>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0017000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00180019001A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001B001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0003>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Cy3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.67299652 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 214.49499512 m 416.75 214.49499512 l 416.75 245.69499207 l -1.45000005 245.69499207 l h f* Q q 1 0 0 1 0 214.49499512 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 245.69500732 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 273.63400269 cm q /GS2 gs 1 g 0.375 0.75 m 101.92500305 0.75 l 101.92500305 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 102.92500305 -0.25 l 102.92500305 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 54.72100067 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 102.67500305 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 102.67500305 156.75 l h f* Q q 1 0 0 1 102.30000305 0 cm -0.625 -0.25 m 321.125 -0.25 l 321.125 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunoglob)1(u)-1(lin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.82900238 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.32900238 11.72200012 Tm [(G)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.02200317 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.52200317 11.72200012 Tm [(\(IgG)1(\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.6289978 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.1289978 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.69000244 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.19000244 11.72200012 Tm [(one)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.56399536 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.06399536 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.90600586 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.40600586 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.40699768 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.90699768 11.72200012 Tm [(most)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.58099365 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.08099365 11.72200012 Tm [(ab)1(u)-1(nd)1(ant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.52600098 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.02600098 11.72200012 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 284.49899292 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.99899292 11.72200012 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 296.94000244 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 301.44000244 11.72200012 Tm [(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(rum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.41600037 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.91600037 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.31200027 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81200027 27.3220005 Tm [(normal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.31900024 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.81900024 27.3220005 Tm [(leve)-1(ls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.71199799 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.21199799 27.3220005 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.28399658 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.78399658 27.3220005 Tm [(8-17)] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.51100159 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.01100159 27.3220005 Tm [(mg/ml)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.87399292 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.37399292 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.31500244 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.81500244 27.3220005 Tm [(ad)1(u)-1(lt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.83999634 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.33999634 27.3220005 Tm [(bloo)1(d.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 273.8500061 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.3500061 27.3220005 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 293.44500732 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 297.94500732 27.3220005 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 304.50601196 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 309.00601196 27.3220005 Tm [(i)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(mpo)1(rtant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.56600189 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.06600189 42.92200089 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.34400177 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.84400177 42.92200089 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.54799652 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.04799652 42.92200089 Tm [(defense)] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.95600128 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.45600128 42.92200089 Tm [(ag)1(ainst)] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.62199402 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.12199402 42.92200089 Tm [(mic)-1(r)1(oorg)1(anisms)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.21699524 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.71699524 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.9940033 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.4940033 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 263.49499512 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.99499512 42.92200089 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 311.37799072 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.51799965 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.01799965 58.52199936 Tm [(pro)1(duc)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.60300064 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.10299683 58.52199936 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.61499786 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.11499786 58.52199936 Tm [(B)] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.76200104 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.26200104 58.52199936 Tm [(lymphocytes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.76699829 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.26699829 58.52199936 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.40800476 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.90800476 58.52199936 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.88299561 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.38299561 58.52199936 Tm [(pa)1(rt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.89500427 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.39500427 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.23699951 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.73699951 58.52199936 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.44099426 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.94099426 58.52199936 Tm [(ad)1(apt)1(ive)] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.97399902 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.47399902 58.52199936 Tm [(immun)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 302.93301392 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 307.43301392 58.52199936 Tm [(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(esponse.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.72700119 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.22700119 74.12200165 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.0340004 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.5340004 74.12200165 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.6289978 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.1289978 74.12200165 Tm [(molec)-1(ule)] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.34600067 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.84600067 74.12200165 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.52799988 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.02799988 74.12200165 Tm [(tw)1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.20899963 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.70899963 74.12200165 Tm [(separa)1(te)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.57499695 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.07499695 74.12200165 Tm [(func)-1(t)1(ions;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.147995 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.647995 74.12200165 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.72299194 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.22299194 74.12200165 Tm [(bind)] TJ ET EMC /P <> BDC BT 1 0 0 -1 286.66900635 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 291.16900635 74.12200165 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 300.24398804 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 304.74398804 74.12200165 Tm [(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(he)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.64799976 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.14799976 89.72200012 Tm [(pa)1(tho)1(gen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.89599991 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.39599991 89.72200012 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.61799622 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.11799622 89.72200012 Tm [(eli)-1(cited)] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.13899994 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.63899994 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.63999939 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.13999939 89.72200012 Tm [(response)] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.13699341 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.63699341 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.91400146 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.41400146 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.48899841 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.98899841 89.72200012 Tm [(rec)-1(ruit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.77600098 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.27600098 89.72200012 Tm [(ot)1(her)] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.43499756 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 274.93499756 89.72200012 Tm [(ce)-1(lls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 293.51098633 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 298.01098633 89.72200012 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.75699997 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.25699997 105.3219986 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.63999939 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.13999939 105.3219986 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.21499634 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.71499634 105.3219986 Tm [(dest)1(roy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.01899719 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.51899719 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.51999664 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.01999664 105.3219986 Tm [(antig)1(e)-1(n.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.86399841 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.36399841 105.3219986 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.17100525 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.67100525 105.3219986 Tm [(var)1(i)-1(a)1(bility)] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.22599792 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.72599792 105.3219986 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.56799316 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.06799316 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.06900024 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.56900024 105.3219986 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 279.66400146 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 284.16400146 105.3219986 Tm [(po)1(ol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 303.75 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 308.25 105.3219986 Tm [(i)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 4.16599989 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.66600037 120.92199707 Tm [(gene)-1(r)1(ated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.80899811 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.30899811 120.92199707 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.82099915 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.32099915 120.92199707 Tm [(soma)1(tic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.87799835 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.37799835 120.92199707 Tm [(rec)-1(o)1(mbination)] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.26800537 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.76800537 120.92199707 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.04499817 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.54499817 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.54600525 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.04600525 120.92199707 Tm [(number)] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.86199951 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.36199951 120.92199707 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.20401001 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 268.70401001 120.92199707 Tm [(speci)-1(f)1(ic)-1(it)1(i)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(es)] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.27200031 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.77200031 136.52200317 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.71299934 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.21299934 136.52200317 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.73400116 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.23400116 136.52200317 Tm [(individual)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.11799622 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.61799622 136.52200317 Tm [(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.94599915 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.44599915 136.52200317 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.42099762 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.92099762 136.52200317 Tm [(given)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.44900513 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.94900513 136.52200317 Tm [(time)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.23699951 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.73699951 136.52200317 Tm [(po)1(i)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.50100708 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.00100708 136.52200317 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.56199646 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.06199646 136.52200317 Tm [(estimat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.70700073 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.20700073 136.52200317 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.28201294 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.78201294 136.52200317 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.63598633 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 276.13598633 136.52200317 Tm [(10)-1(11)] TJ ET EMC /P <> BDC BT 1 0 0 -1 297.24700928 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 301.74700928 136.52200317 Tm [(va)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(riant)1(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.03800011 152.12199402 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 156.75 cm q /GS2 gs 1 g 0.375 0.75 m 101.92500305 0.75 l 101.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 102.92500305 -0.25 l 102.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 56.50899887 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 102.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 102.67500305 16.35000038 l h f* Q q 1 0 0 1 102.30000305 0 cm -0.625 -0.25 m 321.125 -0.25 l 321.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(1/)-1(10)-1(0-100)-1(0)] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.96099854 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.46099854 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.73899841 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.23899841 11.72200012 Tm [(FCM)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.83399963 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.33399963 11.72200012 Tm [(1/)-1(10)-1(0-100)-1(0)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.29499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.79499817 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.07299805 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.57299805 11.72200012 Tm [(Immunofluoresce)-1(nc)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.17498779 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 102.30000305 0.75 m 102.30000305 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 102.30000305 157.5 m 102.30000305 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.125 m 422.42498779 157.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 173.4750061 m 423.17498779 173.4750061 l S Q Q q 1 0 0 1 0 447.48400879 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 475.42300415 cm Q Q 1 0 0 -1 0 841.90002441 cm
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