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61.9640007 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 -25 61.9640007 Tm [(Cy3)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -6.70200348 61.9640007 Tm [<0003000400050006000700080009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 69.42300415 61.9640007 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.63499451 61.9640007 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.00900269 61.9640007 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 82.6780014 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Cy3-conj)-1(ugate)1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.63999939 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.01400757 12.82499981 Tm [(Goat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.72200012 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.09599304 12.82499981 Tm [(anti)-1(-rat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.99099731 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.36500549 12.82499981 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.57699585 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 116.21700287 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0010001100120013000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150003000400160007>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 126 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 149.7559967 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0017>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0018000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<0019001A001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001C001D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 183.29499817 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0003>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Cy3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.67299652 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 216.83399963 m 416.75 216.83399963 l 416.75 248.03399658 l -1.45000005 248.03399658 l h f* Q q 1 0 0 1 0 216.83399963 cm /P <> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 275.97299194 cm q 1 g 0.375 0.75 m 108.67500305 0.75 l 108.67500305 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 109.67500305 -0.25 l 109.67500305 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 109.42500305 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 109.42500305 156.75 l h f* Q q 1 0 0 1 109.05000305 0 cm -0.625 -0.25 m 314.375 -0.25 l 314.375 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Immunoglob)1(u)-1(lin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.82900238 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.32900238 11.72200012 Tm [(G)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.02200317 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.52200317 11.72200012 Tm [(\(IgG)1(\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.6289978 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.1289978 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.69000244 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.19000244 11.72200012 Tm [(one)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.56399536 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.06399536 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.90600586 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.40600586 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.40699768 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.90699768 11.72200012 Tm [(most)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.58099365 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.08099365 11.72200012 Tm [(ab)1(u)-1(nd)1(ant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.52600098 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.02600098 11.72200012 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 284.49899292 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.99899292 11.72200012 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 296.94000244 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 301.44000244 11.72200012 Tm [(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(erum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.52199936 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.02199936 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.41799927 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.91799927 27.3220005 Tm [(normal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.42500305 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.92500305 27.3220005 Tm [(leve)-1(ls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.81800079 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.31800079 27.3220005 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.38999939 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.88999939 27.3220005 Tm [(8-17)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.61700439 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.11700439 27.3220005 Tm [(mg/mL)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.20399475 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.70399475 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.64500427 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.14500427 27.3220005 Tm [(ad)1(u)-1(lt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.16999817 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.66999817 27.3220005 Tm [(bloo)1(d.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 281.17999268 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 285.67999268 27.3220005 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 300.7749939 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 6.56099987 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 11.06099987 42.92200089 Tm [(impor)1(tant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.02199936 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.52199936 42.92200089 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.80000305 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.30000305 42.92200089 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.0039978 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.5039978 42.92200089 Tm [(defense)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.41200256 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.91200256 42.92200089 Tm [(ag)1(ainst)] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.07800293 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.57800293 42.92200089 Tm [(mic)-1(r)1(oorg)1(anisms)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.67300415 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.17300415 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.45001221 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.95001221 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 276.95098877 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 281.45098877 42.92200089 Tm [(mole)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(cu)-1(les)] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.72699928 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.22699928 58.52199936 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.74499893 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.24499893 58.52199936 Tm [(pro)1(duc)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.83000183 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.33000183 58.52199936 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.84200287 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.34200287 58.52199936 Tm [(B)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.98899841 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.48899841 58.52199936 Tm [(lymphocytes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.9940033 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.4940033 58.52199936 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.63499451 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.13499451 58.52199936 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.11000061 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.61000061 58.52199936 Tm [(pa)1(rt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.12199402 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.62199402 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.46400452 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.96400452 58.52199936 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.66799927 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.16799927 58.52199936 Tm [(ad)1(apt)1(ive)] TJ ET EMC /P <> BDC BT 1 0 0 -1 289.20098877 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 293.70098877 58.52199936 Tm [(im)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(mune)] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.63100052 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.13100052 74.12200165 Tm [(response.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.29499817 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.79499817 74.12200165 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.60199738 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.10199738 74.12200165 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.1969986 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.6969986 74.12200165 Tm [(molec)-1(ule)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.91400146 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.41400146 74.12200165 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.09599304 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.59599304 74.12200165 Tm [(tw)1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.7769928 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.2769928 74.12200165 Tm [(separa)1(te)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.14300537 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.64300537 74.12200165 Tm [(func)-1(t)1(ions,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 281.71600342 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 286.21600342 74.12200165 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 295.29098511 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 299.79098511 74.12200165 Tm [(b)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ind)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.69799995 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.19799995 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.27300072 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.77300072 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.77399826 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.27399826 89.72200012 Tm [(pa)1(tho)1(gen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.02200317 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.52200317 89.72200012 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.7440033 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.2440033 89.72200012 Tm [(eli)-1(cited)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.26499939 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.76499939 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.76600647 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.26600647 89.72200012 Tm [(response)] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.26300049 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.76300049 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.03999329 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.53999329 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.61500549 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.11500549 89.72200012 Tm [(rec)-1(ruit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 277.90200806 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 282.40200806 89.72200012 Tm [(ot)1(her)] TJ ET EMC /P <> BDC BT 1 0 0 -1 305.56100464 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ce)-1(lls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.57600021 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.07600021 105.3219986 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.35300064 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.85300064 105.3219986 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.23600006 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.73600006 105.3219986 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.81099701 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.31099701 105.3219986 Tm [(dest)1(roy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.61500549 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.11500549 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.11599731 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.61599731 105.3219986 Tm [(antig)1(e)-1(n.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.46000671 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.96000671 105.3219986 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.76699829 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.26699829 105.3219986 Tm [(var)1(i)-1(a)1(bility)] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.82199097 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.32199097 105.3219986 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 275.16400146 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 279.66400146 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 293.66500854 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 298.16500854 105.3219986 Tm [(I)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(gG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.44999981 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.95000076 120.92199707 Tm [(po)1(ol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.5359993 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.0359993 120.92199707 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.59700012 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.09700012 120.92199707 Tm [(gene)-1(r)1(ated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.23999786 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.73999786 120.92199707 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.2519989 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.7519989 120.92199707 Tm [(soma)1(tic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.30900574 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.80900574 120.92199707 Tm [(rec)-1(o)1(mbination)] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.69900513 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.19900513 120.92199707 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.47599792 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.97599792 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.977005 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.47698975 120.92199707 Tm [(number)] TJ ET EMC /P <> BDC BT 1 0 0 -1 294.29299927 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 298.79299927 120.92199707 Tm [(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(f)] TJ ET EMC /P <> BDC BT 1 0 0 -1 3.11999989 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 7.61999989 136.52200317 Tm [(speci)-1(f)1(ic)-1(it)1(i)-1(es)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.99300003 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.49300003 136.52200317 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.43399811 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.93399811 136.52200317 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.45500183 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.95500183 136.52200317 Tm [(individual)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.83900452 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.33900452 136.52200317 Tm [(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.66700745 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.16700745 136.52200317 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.14199829 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.64199829 136.52200317 Tm [(given)] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.16999817 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.66999817 136.52200317 Tm [(time)] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.95799255 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.45799255 136.52200317 Tm [(po)1(i)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.22200012 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.72200012 136.52200317 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.28300476 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.78300476 136.52200317 Tm [(estimat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 290.42800903 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 294.92800903 136.52200317 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 304.00299072 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.85400009 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.35400009 152.12199402 Tm [(10)-1(11)] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.46500015 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.96500015 152.12199402 Tm [(var)1(i)-1(a)1(n)-1(t)1(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.7009964 152.12199402 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 156.75 cm q 1 g 0.375 0.75 m 108.67500305 0.75 l 108.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 109.67500305 -0.25 l 109.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 109.42500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 109.42500305 16.35000038 l h f* Q q 1 0 0 1 109.05000305 0 cm -0.625 -0.25 m 314.375 -0.25 l 314.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(1/)-1(10)-1(0-100)-1(0)] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.96099854 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.46099854 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.73899841 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.23899841 11.72200012 Tm [(Immunofluoresce)-1(nc)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.84100342 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 173.1000061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.05000305 0.75 m 109.05000305 156.75 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.05000305 157.5 m 109.05000305 173.1000061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 173.1000061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.125 m 422.42498779 157.125 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 173.4750061 m 423.17498779 173.4750061 l S Q Q q 1 0 0 1 0 449.82299805 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 477.76199341 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 505.70098877 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 533.64001465 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 561.57897949 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 589.51800537 cm Q Q 1 0 0 -1 0 841.90002441 cm
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