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Tf 1 0 0 -1 334.82199097 23.67700005 Tm 0 Tr [(IgG)] TJ ET EMC /P <</MCID 7 >> BDC BT 1 0 0 -1 365.13598633 23.67700005 Tm /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 63 12.82499981 Tm [(Alexa)] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 86.28700256 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 88.66100311 12.82499981 Tm [(Fl)-1(uo)-1(r)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 110.60900116 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 112.98300171 12.82499981 Tm [(488)] TJ ET EMC /P <</Lang (zh-CN) /MCID 15 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 131.57299805 12.82499981 Tm [<000300040005000600070008>] TJ ET EMC /P <</MCID 16 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 197.19799805 12.82499981 Tm [(IgG)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 211.41000366 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 213.78399658 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 19 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 20 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Alexa)] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 86.28700256 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 88.66100311 12.82499981 Tm [(Fl)-1(uo)-1(r)] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 110.60900116 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 112.98300171 12.82499981 Tm [(488-conj)-1(ugate)1(d)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 179.91499329 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 182.28900146 12.82499981 Tm [(Rabb)-1(it)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 209.97999573 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 212.35400391 12.82499981 Tm [(anti)-1(-mou)-1(se)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 260.81399536 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 263.18798828 12.82499981 Tm [(IgG)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 277.3999939 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 33 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F001000110012000D>] TJ ET EMC /P <</MCID 34 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 35 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001300140003000400150006>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 126 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 147 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0016>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0017000D>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00180019001A>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001B001C>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0003>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0004>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000D>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Alexa)] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 86.28700256 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 88.66100311 12.82499981 Tm [(Fl)-1(uo)-1(r)] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 110.60900116 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 112.98300171 12.82499981 Tm [(488)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 128.94799805 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 214.49499512 m 416.75 214.49499512 l 416.75 245.69499207 l -1.45000005 245.69499207 l h f* Q q 1 0 0 1 0 214.49499512 cm /P <</MCID 58 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 59 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 60 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 245.69500732 cm /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 273.63400269 cm q /GS2 gs 1 g 0.375 0.75 m 108.67500305 0.75 l 108.67500305 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 109.67500305 -0.25 l 109.67500305 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 62 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 54.72100067 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.42500305 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 109.42500305 156.75 l h f* Q q 1 0 0 1 109.05000305 0 cm -0.625 -0.25 m 314.375 -0.25 l 314.375 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 64 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunoglob)1(u)-1(lin)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 71.82900238 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 76.32900238 11.72200012 Tm [(G)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 83.02200317 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 87.52200317 11.72200012 Tm [(\(IgG)1(\))] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 108.6289978 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 113.1289978 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 119.69000244 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 124.19000244 11.72200012 Tm [(one)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 140.56399536 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 145.06399536 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 153.90600586 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 158.40600586 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 172.40699768 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 176.90699768 11.72200012 Tm [(most)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 198.58099365 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 203.08099365 11.72200012 Tm [(ab)1(u)-1(nd)1(ant)] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 244.52600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 249.02600098 11.72200012 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 284.49899292 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 288.99899292 11.72200012 Tm [(in)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 296.94000244 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 301.44000244 11.72200012 Tm [(s)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(erum)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 22.52199936 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 27.02199936 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 45.41799927 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 49.91799927 27.3220005 Tm [(normal)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 80.42500305 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 84.92500305 27.3220005 Tm [(leve)-1(ls)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 108.81800079 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 113.31800079 27.3220005 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 150.38999939 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 154.88999939 27.3220005 Tm [(8-17)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 174.61700439 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 179.11700439 27.3220005 Tm [(mg/ml)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 207.97999573 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 212.47999573 27.3220005 Tm [(in)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 220.42100525 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 224.92100525 27.3220005 Tm [(ad)1(u)-1(lt)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 246.94599915 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 251.44599915 27.3220005 Tm [(bloo)1(d.)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 278.95599365 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 283.45599365 27.3220005 Tm [(IgG)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 298.55099487 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 303.05099487 27.3220005 Tm [(i)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(s)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 4.16599989 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 8.66600037 42.92200089 Tm [(impor)1(tant)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 51.6269989 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 56.1269989 42.92200089 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 68.40499878 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 72.90499878 42.92200089 Tm [(our)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 87.60900116 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 92.10900116 42.92200089 Tm [(defense)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 126.01699829 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 130.51699829 42.92200089 Tm [(ag)1(ainst)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 161.68299866 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 166.18299866 42.92200089 Tm [(mic)-1(r)1(oorg)1(anisms)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 235.27799988 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 239.77799988 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 256.05499268 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 260.55499268 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 274.55599976 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 279.05599976 42.92200089 Tm [(molec)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ule)-1(s)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 17.21299934 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 21.71299934 58.52199936 Tm [(are)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 35.23099899 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 39.73099899 58.52199936 Tm [(pro)1(duc)-1(ed)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 81.31600189 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 85.81600189 58.52199936 Tm [(by)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 96.32800293 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 100.82800293 58.52199936 Tm [(B)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 106.47499847 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 110.97499847 58.52199936 Tm [(lymphocytes)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 165.47999573 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 169.97999573 58.52199936 Tm [(as)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 179.1210022 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 183.6210022 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 188.59599304 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 193.09599304 58.52199936 Tm [(pa)1(rt)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 210.60800171 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 215.10800171 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 223.94999695 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 228.44999695 58.52199936 Tm [(our)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 243.15400696 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 247.65400696 58.52199936 Tm [(ad)1(apt)1(ive)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 284.68701172 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 289.18701172 58.52199936 Tm [(im)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(mune)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 24.63100052 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 29.13100052 74.12200165 Tm [(response.)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 70.29499817 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 74.79499817 74.12200165 Tm [(The)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 90.60199738 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 95.10199738 74.12200165 Tm [(IgG)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 110.1969986 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 114.6969986 74.12200165 Tm [(molec)-1(ule)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 153.91400146 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 158.41400146 74.12200165 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 173.09599304 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 177.59599304 74.12200165 Tm [(tw)1(o)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 193.7769928 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 198.2769928 74.12200165 Tm [(separa)1(te)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 235.14300537 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 239.64300537 74.12200165 Tm [(func)-1(t)1(ions;)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 281.71600342 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 286.21600342 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 295.29098511 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 299.79098511 74.12200165 Tm [(b)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ind)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 13.69799995 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 18.19799995 89.72200012 Tm [(to)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 27.27300072 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 31.77300072 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 45.77399826 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 50.27399826 89.72200012 Tm [(pa)1(tho)1(gen)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 92.02200317 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 96.52200317 89.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 113.7440033 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 118.2440033 89.72200012 Tm [(eli)-1(cited)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 149.26499939 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 153.76499939 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 167.76600647 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 172.26600647 89.72200012 Tm [(response)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 211.26300049 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 215.76300049 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 232.03999329 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 236.53999329 89.72200012 Tm [(to)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 245.61500549 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 250.11500549 89.72200012 Tm [(rec)-1(ruit)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 277.90200806 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 282.40200806 89.72200012 Tm [(ot)1(her)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 305.56100464 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ce)-1(lls)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 18.57600021 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 23.07600021 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 39.35300064 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 43.85300064 105.3219986 Tm [(molec)-1(ules)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 87.23600006 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 91.73600006 105.3219986 Tm [(to)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 100.81099701 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 105.31099701 105.3219986 Tm [(dest)1(roy)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 137.61500549 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 142.11500549 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 156.11599731 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 160.61599731 105.3219986 Tm [(antig)1(e)-1(n.)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 195.46000671 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 199.96000671 105.3219986 Tm [(The)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 215.76699829 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 220.26699829 105.3219986 Tm [(var)1(i)-1(a)1(bility)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 261.82199097 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 266.32199097 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 275.16400146 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 279.66400146 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 293.66500854 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 298.16500854 105.3219986 Tm [(I)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(gG)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 12.44999981 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 16.95000076 120.92199707 Tm [(po)1(ol)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 36.5359993 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 41.0359993 120.92199707 Tm [(is)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 47.59700012 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 52.09700012 120.92199707 Tm [(gene)-1(r)1(ated)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 96.23999786 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 100.73999786 120.92199707 Tm [(by)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 111.2519989 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 115.7519989 120.92199707 Tm [(soma)1(tic)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 149.30900574 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 153.80900574 120.92199707 Tm [(rec)-1(o)1(mbination)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 216.69900513 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 221.19900513 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 237.47599792 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 241.97599792 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 255.977005 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 260.47698975 120.92199707 Tm [(number)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 294.29299927 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 298.79299927 120.92199707 Tm [(o)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(f)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 3.11999989 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 7.61999989 136.52200317 Tm [(speci)-1(f)1(ic)-1(it)1(i)-1(es)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 56.99300003 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 61.49300003 136.52200317 Tm [(in)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 69.43399811 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 73.93399811 136.52200317 Tm [(an)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 84.45500183 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 88.95500183 136.52200317 Tm [(individual)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 130.83900452 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 135.33900452 136.52200317 Tm [(at)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 143.66700745 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 148.16700745 136.52200317 Tm [(a)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 153.14199829 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 157.64199829 136.52200317 Tm [(given)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 181.16999817 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 185.66999817 136.52200317 Tm [(time)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 204.95799255 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 209.45799255 136.52200317 Tm [(po)1(i)-1(nt)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 232.22200012 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 236.72200012 136.52200317 Tm [(is)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 243.28300476 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 247.78300476 136.52200317 Tm [(estimat)1(e)-1(d)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 290.42800903 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 294.92800903 136.52200317 Tm [(to)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 304.00299072 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(be)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 10.85400009 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 15.35400009 152.12199402 Tm [(10)-1(11)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 36.46500015 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 40.96500015 152.12199402 Tm [(var)1(i)-1(a)1(n)-1(t)1(s.)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 76.7009964 152.12199402 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 156.75 cm q /GS2 gs 1 g 0.375 0.75 m 108.67500305 0.75 l 108.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 109.67500305 -0.25 l 109.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 275 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations)] TJ ET EMC /P <</MCID 276 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 56.50899887 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.42500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 109.42500305 16.35000038 l h f* Q q 1 0 0 1 109.05000305 0 cm -0.625 -0.25 m 314.375 -0.25 l 314.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 277 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(1/)-1(10)-1(0-100)-1(0)] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 49.96099854 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 54.46099854 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 66.73899841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 71.23899841 11.72200012 Tm [(FCM)] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 90.83399963 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 95.33399963 11.72200012 Tm [(1/)-1(10)-1(0-100)-1(0)] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 145.29499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 149.79499817 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 162.07299805 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 166.57299805 11.72200012 Tm [(Immunofluoresce)-1(nc)-1(e)] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 257.17498779 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.05000305 0.75 m 109.05000305 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.05000305 157.5 m 109.05000305 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.125 m 422.42498779 157.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 173.4750061 m 423.17498779 173.4750061 l S Q Q q 1 0 0 1 0 447.48400879 cm /P <</MCID 289 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 475.42300415 cm /P <</MCID 290 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 503.36199951 cm /P <</MCID 291 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 531.30102539 cm /P <</MCID 292 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 559.23999023 cm /P <</MCID 293 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 587.17901611 cm Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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