%PDF-1.5
%ÈÈÈÈÈÈ?1 0 obj
<>
endobj
2 0 obj
<>/Metadata 79 0 R>>
endobj
3 0 obj
<>
endobj
4 0 obj
<>/ExtGState<>/XObject<>>>/Group<>/StructParents 0/Tabs/S>>
endobj
5 0 obj
<>stream
1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 269.45001221 0 0 -90.09999847 0 90.09999847 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 142.96200562 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 236.81399536 23.67700005 Tm 0 Tr [(IgM)] TJ ET EMC /P <> BDC BT 1 0 0 -1 272.3380127 23.67700005 Tm /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000700080009000A000B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 107.625 12.82499981 Tm [(IgM)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.19000244 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.56400299 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000C00080009000A000B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.73600006 12.82499981 Tm [(Anti-)-1(Human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.46200562 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.83599854 12.82499981 Tm [(IgM)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.40100098 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000D000E000F0010000B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<0011001200130005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 105 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0015000B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 214.49499512 m 416.75 214.49499512 l 416.75 245.69499207 l -1.45000005 245.69499207 l h f* Q q 1 0 0 1 0 214.49499512 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 245.69500732 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 273.63400269 cm q /GS2 gs 1 g 0.375 0.75 m 126.67500305 0.75 l 126.67500305 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 127.67500305 -0.25 l 127.67500305 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 127.42500305 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 127.42500305 172.3500061 l h f* Q q 1 0 0 1 127.05000305 0 cm -0.625 -0.25 m 296.375 -0.25 l 296.375 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(IgM)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.19599915 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.69599915 11.72200012 Tm [(normally)] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.36199951 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.86199951 11.72200012 Tm [(constitut)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.08100128 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.58100128 11.72200012 Tm [(ab)1(out)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.92399597 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.42399597 11.72200012 Tm [(10)-1(%)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.98599243 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.48599243 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.32800293 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.82800293 11.72200012 Tm [(serum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.51600647 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.01600647 11.72200012 Tm [(immun)-1(o)1(glob)1(u)-1(lin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 6.33300018 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.83300018 27.3220005 Tm [(IgM)] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.02899933 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.52899933 27.3220005 Tm [(antib)1(ody)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.78800201 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.28800201 27.3220005 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.84899902 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.34899902 27.3220005 Tm [(pro)1(min)-1(ent)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.63499451 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.13499451 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.07600403 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.57600403 27.3220005 Tm [(early)] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.2519989 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.7519989 27.3220005 Tm [(immun)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.21099854 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.71099854 27.3220005 Tm [(responses)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.87399292 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.37399292 27.3220005 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.44900513 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 274.94900513 27.3220005 Tm [(m)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ost)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.24100018 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.74099922 42.92200089 Tm [(antig)1(e)-1(ns)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.58499908 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.08499908 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.36199951 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.86199951 42.92200089 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.42299652 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.92299652 42.92200089 Tm [(larg)1(e)-1(ly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.75099945 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.25099945 42.92200089 Tm [(confine)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.95599365 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.45599365 42.92200089 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.53100586 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.03100586 42.92200089 Tm [(plas)1(ma)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.72200012 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.22200012 42.92200089 Tm [(due)] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.6309967 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.1309967 42.92200089 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.20599365 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.70599365 42.92200089 Tm [(it's)] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.92700195 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.42700195 42.92200089 Tm [(larg)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.0960083 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(size.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.25900078 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.75900078 58.52199936 Tm [(Monomeric)] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.4260025 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.9260025 58.52199936 Tm [(IgM)] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.12200165 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.62200165 58.52199936 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.18299866 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.68299866 58.52199936 Tm [(expressed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.83700562 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.33700562 58.52199936 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.47799683 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.97799683 58.52199936 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.95300293 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.45300293 58.52199936 Tm [(membrane)] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.23699951 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.73699951 58.52199936 Tm [(bo)1(u)-1(nd)] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.05499268 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.55499268 58.52199936 Tm [(antib)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(od)1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.24200058 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.74200058 74.12200165 Tm [(on)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.00999832 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.50999832 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.51100159 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.01100159 74.12200165 Tm [(surfa)1(c)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.87400055 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.37400055 74.12200165 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.21600342 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.71600342 74.12200165 Tm [(B)] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.36299896 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.86299896 74.12200165 Tm [(ce)-1(lls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.43899536 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.93899536 74.12200165 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.21600342 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.71600342 74.12200165 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.85699463 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.35699463 74.12200165 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.33200073 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.83200073 74.12200165 Tm [(pentamer)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.53599548 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.03599548 74.12200165 Tm [(wh)1(e)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.33599854 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.83599854 74.12200165 Tm [(sec)-1(rete)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.75699997 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.25699997 89.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.7689991 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.2689991 89.72200012 Tm [(plas)1(ma)] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.95999908 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.45999908 89.72200012 Tm [(ce)-1(lls.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.20200348 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.70200348 89.72200012 Tm [(Due)] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.20999908 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.70999908 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.78500366 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.28500366 89.72200012 Tm [(it's)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.5059967 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.0059967 89.72200012 Tm [(hig)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.24099731 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.74099731 89.72200012 Tm [(valenc)-1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.76400757 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.26400757 89.72200012 Tm [(IgM)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.46000671 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.96000671 89.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.52099609 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.02099609 89.72200012 Tm [(more)] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.71899414 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.21899414 89.72200012 Tm [(efficie)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.89900017 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.39900017 105.3219986 Tm [(th)1(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.81399918 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.31399918 105.3219986 Tm [(ot)1(her)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.47299957 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.97299957 105.3219986 Tm [(isot)1(y)-1(p)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.39299774 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.89299774 105.3219986 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.45400238 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.95400238 105.3219986 Tm [(binding)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.0980072 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.5980072 105.3219986 Tm [(antig)1(e)-1(ns)] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.44200134 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.94200134 105.3219986 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.33799744 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.83799744 105.3219986 Tm [(repeating)] TJ ET EMC /P <> BDC BT 1 0 0 -1 259.26098633 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 263.76098633 105.3219986 Tm [(epito)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(pes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.02099991 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.52099991 120.92199707 Tm [(\(virus)] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.79399872 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.29399872 120.92199707 Tm [(pa)1(rticle)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.38200378 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.88200378 120.92199707 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.15899658 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.65899658 120.92199707 Tm [(red)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.95899963 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.45899963 120.92199707 Tm [(bloo)1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.80200195 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.30200195 120.92199707 Tm [(ce)-1(lls\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.88400269 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.38400269 120.92199707 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.66099548 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.16099548 120.92199707 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.72200012 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.22200012 120.92199707 Tm [(more)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.91999817 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.41999817 120.92199707 Tm [(efficie)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 277.07501221 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 281.57501221 120.92199707 Tm [(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(ha)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.06200027 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.56200027 136.52200317 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.6570015 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.1570015 136.52200317 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.09799957 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.59799957 136.52200317 Tm [(activiat)1(in)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.97799683 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.47799683 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.47899628 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.97899628 136.52200317 Tm [(compleme)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.33500671 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.83500671 136.52200317 Tm [(pa)1(thw)1(ay.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.46299744 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.96299744 136.52200317 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.77000427 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.27000427 136.52200317 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 263.78601074 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 268.28601074 136.52200317 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 280.56399536 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.0010004 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.50099945 152.12199402 Tm [(mu)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.47999954 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.97999954 152.12199402 Tm [(constant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.15299988 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.65299988 152.12199402 Tm [(region)] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.61499786 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.11499786 152.12199402 Tm [(contains)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.33000183 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.83000183 152.12199402 Tm [(fo)1(u)-1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.65400696 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.15400696 152.12199402 Tm [(do)1(mains)] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.14700317 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.64700317 152.12199402 Tm [(separa)1(ted)] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.26998901 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.76998901 152.12199402 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 273.28201294 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 277.78201294 152.12199402 Tm [(sh)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 167.72200012 Tm [(ort)] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.51099968 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.01099968 167.72200012 Tm [(interven)-1(ing)] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.92199707 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.42199707 167.72200012 Tm [(seque)-1(nce)-1(s)1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.60199738 167.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 172.3500061 cm q /GS2 gs 1 g 0.375 0.75 m 126.67500305 0.75 l 126.67500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 127.67500305 -0.25 l 127.67500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 127.42500305 0.75 m 422.42498779 0.75 l 422.42498779 31.95000076 l 127.42500305 31.95000076 l h f* Q q 1 0 0 1 127.05000305 0 cm -0.625 -0.25 m 296.375 -0.25 l 296.375 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(1/)-1(20)-1(00-10)-1(00)-1(0)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.51699829 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.01699829 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.29499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.79499817 11.72200012 Tm [(ELISA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.53399658 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.03399658 11.72200012 Tm [(1/)-1(10)-1(00-50)-1(00)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.272995 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.772995 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.05099487 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.55099487 11.72200012 Tm [(West)1(e)-1(rn)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.42399597 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.92399597 11.72200012 Tm [(blot)1(ting)] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.19299316 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.69299316 11.72200012 Tm [(1/)-1(20)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(0-10)-1(00)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.28300095 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.78300095 27.3220005 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.06100082 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.56100082 27.3220005 Tm [(Immunohist)1(oc)-1(h)1(e)-1(mist)1(ry/)-1(cytochemistry)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.67700195 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 127.05000305 0.75 m 127.05000305 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 127.05000305 173.1000061 m 127.05000305 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 172.7250061 m 422.42498779 172.7250061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 204.67500305 m 423.17498779 204.67500305 l S Q Q q 1 0 0 1 0 478.68399048 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 506.62298584 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 534.56201172 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 562.50097656 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 590.44000244 cm Q Q 1 0 0 -1 0 841.90002441 cm
endstream
endobj
6 0 obj
<>stream
ºÝºÝÈÈÔÚÏßÊÓÆµÃâ·Ñ
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Ö©Öë´Ê>|
<Îı¾Á´>
<Îı¾Á´>
<Îı¾Á´>
<Îı¾Á´>
<Îı¾Á´>
<Îı¾Á´>