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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 269.45001221 0 0 -90.09999847 0 90.09999847 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 131.772995 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>-4<0005>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 203.53700256 23.67700005 Tm 0 Tr [(IgG)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 239.35099792 23.67700005 Tm 2 Tr [<0006>-4<0007>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 283.52700806 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<00080009000A000B000C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(IgG)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 113.96199799 12.82499981 Tm [<00060007>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 134.96200562 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.21200562 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000D0009000A000B000C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.06500244 12.82499981 Tm [(Anti-)-1(horse)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.84399414 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.21800232 12.82499981 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.42999268 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.80400085 12.82499981 Tm [(Whol)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.83299255 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.20700073 12.82499981 Tm [(ser)1(u)-1(m)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.10299683 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000F00100011000C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<0012001300140004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 105 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.85800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 180.95599365 m 416.75 180.95599365 l 416.75 212.1559906 l -1.45000005 212.1559906 l h f* Q q 1 0 0 1 0 180.95599365 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 212.15600586 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 240.09500122 cm q /GS2 gs 1 g 0.375 0.75 m 137.92500305 0.75 l 137.92500305 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 138.92500305 -0.25 l 138.92500305 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 54.72100067 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 138.67500305 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 138.67500305 172.3500061 l h f* Q q 1 0 0 1 138.30000305 0 cm -0.625 -0.25 m 285.125 -0.25 l 285.125 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunoglob)1(u)-1(lin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.82900238 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.32900238 11.72200012 Tm [(G)] TJ ET EMC /P <> BDC BT /FAAADE 9 Tf 1 0 0 -1 83.02200317 11.72200012 Tm [<000D>] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 92.02200317 11.72200012 Tm [(IgG)] TJ ET EMC /P <> BDC BT /FAAADE 9 Tf 1 0 0 -1 107.11699677 11.72200012 Tm [<000E>] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 116.11699677 11.72200012 Tm [(,is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.84500122 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.34500122 11.72200012 Tm [(one)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.71899414 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.21899414 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.06100464 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.56100464 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.56199646 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.06199646 11.72200012 Tm [(most)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.73599243 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.23599243 11.72200012 Tm [(ab)1(u)-1(nd)1(ant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.68099976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.18099976 11.72200012 Tm [(pro)1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.21299934 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.71299934 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.65399933 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.15399933 27.3220005 Tm [(serum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.84199905 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.34200287 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.73799896 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.23799896 27.3220005 Tm [(normal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.74500275 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.24500275 27.3220005 Tm [(leve)-1(ls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.13800049 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.63800049 27.3220005 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.71000671 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.21000671 27.3220005 Tm [(9.5)-1(-)1(1)-1(2.5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.82600403 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.32600403 27.3220005 Tm [(mg/ml)] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.18899536 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.68899536 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 273.63000488 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ad)1(u)-1(lt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.02499962 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.52499962 42.92200089 Tm [(bloo)1(d.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.03499985 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.53499985 42.92200089 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.62999725 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.12999725 42.92200089 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.69100189 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.19100189 42.92200089 Tm [(impor)1(tant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.1519928 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.6519928 42.92200089 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.92999268 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.42999268 42.92200089 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.13400269 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.63400269 42.92200089 Tm [(defenc)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.88900757 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.38900757 42.92200089 Tm [(ag)1(ainst)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.55499268 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.05499268 42.92200089 Tm [(mic)-1(r)1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(org)1(anisms)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.59600067 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.09600067 58.52199936 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.3730011 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.8730011 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.87400055 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.37400055 58.52199936 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.75700378 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.25700378 58.52199936 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.7749939 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.2749939 58.52199936 Tm [(pro)1(duc)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.86000061 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.36000061 58.52199936 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.87199402 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.37199402 58.52199936 Tm [(B)] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.01899719 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.51899719 58.52199936 Tm [(lymphocyte)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 4.16599989 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.66600037 74.12200165 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.80699921 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.30699921 74.12200165 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.28199959 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.78199959 74.12200165 Tm [(pa)1(rt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.29399872 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.79399872 74.12200165 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.63600159 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.13600159 74.12200165 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.83999634 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.33999634 74.12200165 Tm [(ad)1(apt)1(ive)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.3730011 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.8730011 74.12200165 Tm [(immun)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.33200073 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.83200073 74.12200165 Tm [(response.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.9960022 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.4960022 74.12200165 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.30299377 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.80299377 74.12200165 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.897995 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.397995 74.12200165 Tm [(mole)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(cu)-1(le)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.56100082 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.06100082 89.72200012 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.74300003 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.24300003 89.72200012 Tm [(tw)1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.42399979 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.92399979 89.72200012 Tm [(separa)1(te)] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.79000092 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.29000092 89.72200012 Tm [(func)-1(t)1(ions;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.36300659 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.86300659 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.93800354 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.43800354 89.72200012 Tm [(bind)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.88400269 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.38400269 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.45899963 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.95899963 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.96000671 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.46000671 89.72200012 Tm [(pa)1(tho)1(gen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.20800781 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.70800781 89.72200012 Tm [(th)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.32800007 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.82800007 105.3219986 Tm [(eli)-1(cited)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.84899902 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.34899902 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.34999847 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.84999847 105.3219986 Tm [(response)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.84700012 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.34700012 105.3219986 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.62400055 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.12399292 105.3219986 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.19900513 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.69900513 105.3219986 Tm [(rec)-1(ruit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.48599243 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.98599243 105.3219986 Tm [(ot)1(her)] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.14500427 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.64500427 105.3219986 Tm [(ce)-1(lls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.22099304 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.72099304 105.3219986 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.9980011 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.4980011 105.3219986 Tm [(molec)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(ule)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.21299934 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.71299934 120.92199707 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.78800011 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.2879982 120.92199707 Tm [(dest)1(roy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.59200287 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.09200287 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.09300232 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.59300232 120.92199707 Tm [(antig)1(e)-1(n.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.43699646 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.93699646 120.92199707 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.7440033 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.2440033 120.92199707 Tm [(var)1(i)-1(a)1(bility)] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.79899597 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.29899597 120.92199707 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.14100647 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.64100647 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.64199829 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.14199829 120.92199707 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.23699951 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.73699951 120.92199707 Tm [(po)1(ol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.32299805 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.82299805 120.92199707 Tm [(i)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 4.16599989 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.66600037 136.52200317 Tm [(gene)-1(r)1(ated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.80899811 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.30899811 136.52200317 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.82099915 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.32099915 136.52200317 Tm [(Somat)1(ic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.90599823 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.40599823 136.52200317 Tm [(rec)-1(o)1(mbination)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.29600525 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.79600525 136.52200317 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.07299805 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.57299805 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.57400513 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.07400513 136.52200317 Tm [(number)] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.88999939 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.39001465 136.52200317 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.23199463 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.73199463 136.52200317 Tm [(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(pec)-1(if)1(ic)-1(ities)] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.20700073 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.70700073 152.12199402 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.64799881 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.14799881 152.12199402 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.66899872 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.16899872 152.12199402 Tm [(individual)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.0530014 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.5530014 152.12199402 Tm [(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.8809967 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.3809967 152.12199402 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.35600281 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.85600281 152.12199402 Tm [(given)] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.38400269 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.88400269 152.12199402 Tm [(time)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.17199707 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.67199707 152.12199402 Tm [(po)1(i)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.43600464 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.93600464 152.12199402 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.49699402 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.99699402 152.12199402 Tm [(estimat)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 167.72200012 Tm [(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.75699997 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.25699997 167.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.33200073 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.83200073 167.72200012 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.68600082 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.18600082 167.72200012 Tm [(10)-1(11)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.29700089 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.79699707 167.72200012 Tm [(var)1(i)-1(a)1(n)-1(t)1(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.53299713 167.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 172.3500061 cm q /GS2 gs 1 g 0.375 0.75 m 137.92500305 0.75 l 137.92500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 138.92500305 -0.25 l 138.92500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Applic)1(ations)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 56.50899887 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 138.67500305 0.75 m 422.42498779 0.75 l 422.42498779 31.95000076 l 138.67500305 31.95000076 l h f* Q q 1 0 0 1 138.30000305 0 cm -0.625 -0.25 m 285.125 -0.25 l 285.125 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(1/)-1(10)-1(000)-1(-)1(5)-1(00)-1(00)] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.79499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.29499817 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.57299805 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.07299805 11.72200012 Tm [(ELISA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.81199646 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.31199646 11.72200012 Tm [(1/)-1(10)-1(00-50)-1(00)] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.55099487 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.05099487 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.32899475 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.82899475 11.72200012 Tm [(West)1(e)-1(rn)] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.70199585 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.20199585 11.72200012 Tm [(blot)1(ting)] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.4710083 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.9710083 11.72200012 Tm [(1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(/1)-1(00)-1(-)1(5)-1(00)] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.40599823 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.90599823 27.3220005 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.18399811 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.68399811 27.3220005 Tm [(Immunohist)1(oc)-1(h)1(e)-1(mist)1(ry/)-1(cytoce)-1(h)1(mistry)] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.80000305 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 138.30000305 0.75 m 138.30000305 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 138.30000305 173.1000061 m 138.30000305 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 172.7250061 m 422.42498779 172.7250061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 204.67500305 m 423.17498779 204.67500305 l S Q Q q 1 0 0 1 0 445.14498901 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 473.08401489 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 501.02301025 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 528.9619751 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 556.90100098 cm Q Q 1 0 0 -1 0 841.90002441 cm
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