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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm q 1 0 0 1 132 0 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 0 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 49.67599869 23.67700005 Tm 0 Tr [(NFY)1(A)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 104.52600098 23.67700005 Tm 2 Tr [<0005>-4<0006>-4<0007>-4<0004>-4<0008>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 214.96600342 23.67700005 Tm 0 Tr [( )] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 225.96600342 23.67700005 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 -132 43.75799942 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -132 61.9640007 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <> BDC BT 1 0 0 -1 -79.5 61.9640007 Tm [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -55.875 61.9640007 Tm [(NFYA)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -30.45600128 61.9640007 Tm [<00050006000700040008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 22.04400635 61.9640007 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.29400635 61.9640007 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 82.6780014 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000E000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(N)1(F)-1(YA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.52799988 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.90200043 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.55200195 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.92599487 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.48500061 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.85899353 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.65499878 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 116.21700287 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(HAP)1(2;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.17299652 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.54699707 12.82499981 Tm [(CBF)-1(-A)1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.78099823 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.15499878 12.82499981 Tm [(CBF)-1(-B;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.0249939 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.39900208 12.82499981 Tm [(NF-YA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.40800476 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 149.7559967 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001000110012000F000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 183.29499817 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0014>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0015000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<001B001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 216.83399963 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001D000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(NFYA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.79399872 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 250.3730011 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001F000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 283.9119873 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0020002100220023000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.36599731 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.72799683 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.102005 12.82499981 Tm [(Rat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.3500061 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 317.45098877 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<002400250026000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 350.98999023 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0006000700120027000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 384.5289917 m 416.75 384.5289917 l 416.75 415.72900391 l -1.45000005 415.72900391 l h f* Q q 1 0 0 1 0 384.5289917 cm /P <> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 415.72900391 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 443.66799927 cm q 1 g 0.375 0.75 m 140.17500305 0.75 l 140.17500305 125.55000305 l 0.375 125.55000305 l h f* Q q -0.625 -0.25 m 141.17500305 -0.25 l 141.17500305 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 66.3219986 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 66.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.92500305 0.75 m 422.42498779 0.75 l 422.42498779 125.55000305 l 140.92500305 125.55000305 l h f* Q q 1 0 0 1 140.55000305 0 cm -0.625 -0.25 m 282.875 -0.25 l 282.875 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(one)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.53999329 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.03999329 11.72200012 Tm [(subunit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.33999634 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.83999634 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.68200684 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.18200684 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.15699768 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.65699768 11.72200012 Tm [(tr)1(i)-1(me)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ric)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.34500027 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.84500027 27.3220005 Tm [(complex,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.49100113 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.99100113 27.3220005 Tm [(fo)1(rmin)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.40000153 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.90000153 27.3220005 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.875 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.375 27.3220005 Tm [(hig)1(hly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.76899719 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.26899719 27.3220005 Tm [(conse)-1(rv)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.34599304 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.84599304 27.3220005 Tm [(tr)1(ansc)-1(rip)1(tion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.42999268 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.92999268 27.3220005 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.04901123 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.22200012 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.72200012 42.92200089 Tm [(binds)] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.33399963 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.83399963 42.92200089 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.9090004 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.4090004 42.92200089 Tm [(CCAA)1(T)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.27400208 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.77400208 42.92200089 Tm [(mot)1(ifs)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.96299744 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.46299744 42.92200089 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.40400696 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.90400696 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.90499878 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.40499878 42.92200089 Tm [(pro)1(moter)] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.36199951 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.86199951 42.92200089 Tm [(regions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.99000549 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.49000549 42.92200089 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.43099976 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.93099976 42.92200089 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 259.90600586 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.40600586 42.92200089 Tm [(va)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(riety)] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.05500031 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.55500031 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.39699936 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.89699936 58.52199936 Tm [(gene)-1(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.74500275 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.24500275 58.52199936 Tm [(Subuni)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.57299805 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.07299805 58.52199936 Tm [(A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.40599823 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.90599823 58.52199936 Tm [(asso)1(c)-1(iat)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.44299316 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.94299316 58.52199936 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.33900452 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.83900452 58.52199936 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.81399536 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.31399536 58.52199936 Tm [(tig)1(ht)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.71299744 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.21299744 58.52199936 Tm [(dimer)] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.34100342 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.84100342 58.52199936 Tm [(com)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(po)1(se)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.49900055 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.99900055 74.12200165 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.8409996 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.3409996 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.34199905 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.84199905 74.12200165 Tm [(B)] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.48899841 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.98899841 74.12200165 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.26599884 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.76599884 74.12200165 Tm [(C)] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.78700256 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.28700256 74.12200165 Tm [(subunits,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.91900635 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.41900635 74.12200165 Tm [(resulting)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.11999512 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.61999512 74.12200165 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.56100464 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.06100464 74.12200165 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.03599548 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.53599548 74.12200165 Tm [(tr)1(i)-1(mer)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.69700623 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.19700623 74.12200165 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 259.41900635 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 263.91900635 74.12200165 Tm [(bi)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(nds)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.46899986 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.96899986 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.04400063 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.54399872 89.72200012 Tm [(DNA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.04899979 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.54899979 89.72200012 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.94499969 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.44499969 89.72200012 Tm [(hig)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.68000031 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.18000031 89.72200012 Tm [(speci)-1(f)1(ic)-1(it)1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.64900208 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.14900208 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.42599487 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.92599487 89.72200012 Tm [(af)1(fini)-1(t)1(y.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.75999451 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.25999451 89.72200012 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.06700134 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.56700134 89.72200012 Tm [(seque)-1(nce)] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.41400146 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(speci)-1(f)1(ic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.95700073 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.45700073 105.3219986 Tm [(interactions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.96299744 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.46299744 105.3219986 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.30500031 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.80500031 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.80599976 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.30599976 105.3219986 Tm [(complex)] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.78500366 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.28500366 105.3219986 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.80299377 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.30299377 105.3219986 Tm [(mad)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.57400513 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.07400513 105.3219986 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.58599854 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.08599854 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.08700562 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.58700562 105.3219986 Tm [(A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.91999817 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.41999817 105.3219986 Tm [(sub)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(uni)-1(t)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.00600052 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.50600052 120.92199707 Tm [(sugg)1(e)-1(st)1(in)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.05500031 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.55500031 120.92199707 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.52999878 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.02999878 120.92199707 Tm [(role)] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.69000244 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.19000244 120.92199707 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.33100128 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.83100128 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.83200073 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.33200073 120.92199707 Tm [(regulat)1(ory)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.82200623 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.32200623 120.92199707 Tm [(subunit.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.78799438 120.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 125.55000305 cm q 1 g 0.375 0.75 m 140.17500305 0.75 l 140.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 141.17500305 -0.25 l 141.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.92500305 16.35000038 l h f* Q q 1 0 0 1 140.55000305 0 cm -0.625 -0.25 m 282.875 -0.25 l 282.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(WB)] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.80500031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 141.8999939 cm q 1 g 0.375 0.75 m 140.17500305 0.75 l 140.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 141.17500305 -0.25 l 141.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Name)] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.92500305 16.35000038 l h f* Q q 1 0 0 1 140.55000305 0 cm -0.625 -0.25 m 282.875 -0.25 l 282.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(NFYA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.86199951 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 158.25 cm q 1 g 0.375 0.75 m 140.17500305 0.75 l 140.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 141.17500305 -0.25 l 141.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Immunogen:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.92500305 16.35000038 l h f* Q q 1 0 0 1 140.55000305 0 cm -0.625 -0.25 m 282.875 -0.25 l 282.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Syn)-1(t)1(hesized)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.35400009 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.85400009 11.72200012 Tm [(pept)1(ide)] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.06800079 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.56800079 11.72200012 Tm [(derived)] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.84999847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.3500061 11.72200012 Tm [(fro)1(m)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.06100464 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.56100464 11.72200012 Tm [(internal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.31300354 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.81300354 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.65499878 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.15499878 11.72200012 Tm [(human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.19599915 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.69599915 11.72200012 Tm [(NFYA)1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.7250061 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 174.60002136 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 140.55000305 0.75 m 140.55000305 125.55000305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 140.55000305 126.30000305 m 140.55000305 141.90000916 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 140.55000305 142.65000916 m 140.55000305 158.25001526 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 140.55000305 159.00001526 m 140.55000305 174.60002136 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 174.60002136 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 125.92500305 m 422.42498779 125.92500305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 142.27500916 m 422.42498779 142.27500916 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 158.62501526 m 422.42498779 158.62501526 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 174.97502136 m 423.17498779 174.97502136 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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