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1 0 0 -1 209.16499329 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 211.53900146 12.82499981 Tm [(IgG)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 225.75100708 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 18 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010001100120013000E>] TJ ET EMC /P <</MCID 19 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<0014001500160008>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 105 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 25 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0018000E>] TJ ET EMC /P <</MCID 26 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 27 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<0019001A001B>] TJ ET EMC /P <</MCID 28 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 29 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001C001D>] TJ ET EMC /P <</MCID 30 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 31 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 32 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 33 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0005>] TJ ET EMC /P <</MCID 34 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 35 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000E>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Gol)-1(d)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 83.08699799 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 93.58699799 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 214.49499512 m 416.75 214.49499512 l 416.75 245.69499207 l -1.45000005 245.69499207 l h f* Q q 1 0 0 1 0 214.49499512 cm /P <</MCID 40 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 41 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 42 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 245.69500732 cm /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 273.63400269 cm q /GS2 gs 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 44 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 54.72100067 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 140.17500305 172.3500061 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 46 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunoglob)1(u)-1(lin)] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 71.82900238 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 76.32900238 11.72200012 Tm [(G)] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 83.02200317 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 87.52200317 11.72200012 Tm [(\(IgG)1(\))] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 108.6289978 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 113.1289978 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 119.69000244 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 124.19000244 11.72200012 Tm [(one)] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 140.56399536 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 145.06399536 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 153.90600586 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 158.40600586 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 172.40699768 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 176.90699768 11.72200012 Tm [(most)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 198.58099365 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 203.08099365 11.72200012 Tm [(ab)1(u)-1(nd)1(ant)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 244.52600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 249.02600098 11.72200012 Tm [(pro)1(tei)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ns)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 9.71199989 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 14.21199989 27.3220005 Tm [(in)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 22.15299988 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 26.65299988 27.3220005 Tm [(serum)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 53.3409996 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 57.8409996 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 76.23699951 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 80.73699951 27.3220005 Tm [(normal)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 111.2440033 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 115.7440033 27.3220005 Tm [(leve)-1(ls)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 139.63699341 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 144.13699341 27.3220005 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 181.20899963 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 185.70899963 27.3220005 Tm [(8-17)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 205.43600464 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 209.93600464 27.3220005 Tm [(mg/ml)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 238.79899597 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 243.29899597 27.3220005 Tm [(in)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 251.24000549 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 255.74000549 27.3220005 Tm [(ad)1(u)-1(l)] TJ ET EMC /P 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ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 149.46200562 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 153.96200562 42.92200089 Tm [(defense)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 187.86999512 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 192.36999512 42.92200089 Tm [(ag)1(ainst)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 223.53599548 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 228.03599548 42.92200089 Tm [(mic)-1(r)1(oorg)1(a)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(nisms)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 24.70599937 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 29.20599937 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 45.48300171 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 49.98300171 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 63.98400116 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 68.48400116 58.52199936 Tm [(molec)-1(ules)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 111.86699677 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 116.36699677 58.52199936 Tm [(are)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 129.88499451 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 134.38499451 58.52199936 Tm [(pro)1(duc)-1(ed)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 175.97000122 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 180.47000122 58.52199936 Tm [(by)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 190.98199463 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 195.48199463 58.52199936 Tm [(B)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 201.1289978 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 205.6289978 58.52199936 Tm [(lymphocytes)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 260.13400269 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 264.63400269 58.52199936 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141.0249939 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 145.5249939 74.12200165 Tm [(response.)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 186.68899536 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 191.18899536 74.12200165 Tm [(The)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 206.9960022 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 211.4960022 74.12200165 Tm [(IgG)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 226.59100342 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 231.09100342 74.12200165 Tm [(molec)-1(ule)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 270.30801392 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 14.68200016 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 19.18199921 89.72200012 Tm [(tw)1(o)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 35.36299896 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 39.86299896 89.72200012 Tm [(separa)1(te)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 76.72899628 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 81.22899628 89.72200012 Tm [(func)-1(t)1(ions;)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 123.30200195 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 127.80200195 89.72200012 Tm [(to)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 136.8769989 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 141.3769989 89.72200012 Tm [(bind)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 160.82299805 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 165.32299805 89.72200012 Tm [(to)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 174.397995 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 178.897995 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 192.89900208 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 197.39900208 89.72200012 Tm [(pa)1(tho)1(gen)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 239.14700317 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 243.64700317 89.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 260.86898804 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 265.36898804 89.72200012 Tm [(eli)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ci)-1(t)1(e)-1(d)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 21.125 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 25.625 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 39.62599945 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 44.12599945 105.3219986 Tm [(response)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 83.1230011 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 87.6230011 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 103.90000153 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 108.40000153 105.3219986 Tm [(to)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 117.47499847 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 121.97499847 105.3219986 Tm [(rec)-1(ruit)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 149.76199341 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 154.26199341 105.3219986 Tm [(ot)1(her)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 177.42100525 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 181.92100525 105.3219986 Tm [(ce)-1(lls)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 200.49699402 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 204.99699402 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 221.27400208 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 225.77400208 105.3219986 Tm [(molec)-1(ules)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 269.15701294 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(to)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 9.07499981 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 13.57499981 120.92199707 Tm [(dest)1(roy)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 45.87900162 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 50.37900162 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 64.37999725 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 68.87999725 120.92199707 Tm [(antig)1(e)-1(n.)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 103.72399902 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 108.22399902 120.92199707 Tm [(The)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 124.03099823 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 128.53100586 120.92199707 Tm [(var)1(i)-1(a)1(bility)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 170.08599854 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 174.58599854 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 183.42799377 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 187.92799377 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 201.92900085 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 206.42900085 120.92199707 Tm [(IgG)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 221.52400208 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 226.02400208 120.92199707 Tm [(po)1(ol)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 245.61000061 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 250.11000061 120.92199707 Tm [(is)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 256.67098999 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 261.17098999 120.92199707 Tm [(ge)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(ne)-1(r)1(ated)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 33.27999878 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 37.77999878 136.52200317 Tm [(by)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 48.29199982 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 52.79199982 136.52200317 Tm [(soma)1(tic)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 86.34899902 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 90.84899902 136.52200317 Tm [(rec)-1(o)1(mbination)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 153.73899841 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 158.23899841 136.52200317 Tm [(and)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 174.51600647 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 179.01600647 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 193.01699829 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 197.51699829 136.52200317 Tm [(number)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 231.33299255 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 235.83299255 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 244.67500305 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 249.17500305 136.52200317 Tm [(speci)-1(f)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(ic)-1(it)1(ie)-1(s)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 24.3239994 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 28.8239994 152.12199402 Tm [(in)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 36.76499939 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 41.26499939 152.12199402 Tm [(an)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 51.7859993 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 56.2859993 152.12199402 Tm [(individual)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 98.16999817 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 102.66999817 152.12199402 Tm [(at)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 110.9980011 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 115.4980011 152.12199402 Tm [(a)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 120.47299957 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 124.97299957 152.12199402 Tm [(given)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 148.50100708 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 153.00100708 152.12199402 Tm [(time)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 172.28900146 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 176.78900146 152.12199402 Tm [(po)1(i)-1(nt)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 199.55299377 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 204.05299377 152.12199402 Tm [(is)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 210.61399841 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 215.11399841 152.12199402 Tm [(estimat)1(e)-1(d)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 257.75900269 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 262.25900269 152.12199402 Tm [(to)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 271.33401489 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(be)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 10.85400009 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 15.35400009 167.72200012 Tm [(10)-1(11)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 36.46500015 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 40.96500015 167.72200012 Tm [(var)1(i)-1(a)1(n)-1(t)1(s.)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 76.7009964 167.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 172.3500061 cm q /GS2 gs 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 256 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Applic)1(ations)] TJ ET EMC /P <</MCID 257 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 56.50899887 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 31.95000076 l 140.17500305 31.95000076 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 258 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(1/)-1(20)-1(-)1(1)-1(00)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 39.40599823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 43.90599823 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 56.18399811 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 60.68399811 11.72200012 Tm [(immun)-1(o)1(e)-1(lec)-1(t)1(ron)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 131.93699646 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 136.43699646 11.72200012 Tm [(mic)-1(r)1(osc)-1(o)1(py\(IEM\),)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 210.41499329 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 214.91499329 11.72200012 Tm [(immun)-1(o)1(gold)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 270.61999512 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(st)1(ain)-1(ing)1(\(IGS\),)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 56.8429985 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 61.3429985 27.3220005 Tm [(go)1(l)-1(d)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 80.97299957 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 85.47299957 27.3220005 Tm [(immun)-1(o)1(c)-1(h)1(romat)1(ogra)1(phy)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 193.46400452 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 197.96400452 27.3220005 Tm [(assa)1(y)-1(\(G)1(ICA\))] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 248.71200562 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 204.30000305 cm q /GS2 gs 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 276 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Co)-1(nj)1(uga)1(te)] TJ ET EMC /P <</MCID 277 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 46.49900055 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 278 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Go)1(l)-1(d)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 20.56599998 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 25.06599998 11.72200012 Tm [(\(15)] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 38.62799835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 43.12799835 11.72200012 Tm [(nm\))] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 60.11299896 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 220.65000916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 0.75 m 139.80000305 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 173.1000061 m 139.80000305 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 205.05000305 m 139.80000305 220.65000916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 220.65000916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 172.7250061 m 422.42498779 172.7250061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 204.67500305 m 422.42498779 204.67500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 221.02500916 m 423.17498779 221.02500916 l S Q Q q 1 0 0 1 0 495.03399658 cm /P <</MCID 284 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 522.97302246 cm /P <</MCID 285 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 550.9119873 cm /P <</MCID 286 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 578.85101318 cm Q Q 1 0 0 -1 0 841.90002441 cm 
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