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10.5 Tf 1 0 0 -1 0 30.76399994 Tm /GS2 gs 0 g [<000A000B000C000D000E>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 30.76399994 Tm [(  )] TJ ET EMC /P <</MCID 7 >> BDC BT 1 0 0 -1 63 30.76399994 Tm [(HRP)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 83.29199982 30.76399994 Tm [<0003000400050006000700080009>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 159.41700745 30.76399994 Tm [(IgM)] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 175.98199463 30.76399994 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 178.35600281 30.76399994 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 92.6780014 cm /P <</Lang (zh-CN) /MCID 12 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <</MCID 13 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(HRP-conj)-1(ugate)1(d)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 131.63499451 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 134.00900269 12.82499981 Tm [(Goat)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 154.71699524 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 157.09100342 12.82499981 Tm [(anti)-1(-mou)-1(se)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 205.55099487 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 207.92500305 12.82499981 Tm [(IgM)] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 224.49000549 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 126.21700287 cm /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010001100120013000E>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(HRP)] TJ ET EMC /P <</Lang (zh-CN) /MCID 25 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 83.29199982 12.82499981 Tm [<0003000400140007>] TJ ET EMC /P <</MCID 26 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 125.29199982 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 159.7559967 cm /P <</Lang (zh-CN) /MCID 28 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <</MCID 29 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 30 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <</MCID 31 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 32 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 33 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 34 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 35 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 193.29499817 cm /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0003>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0004>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001C000E>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(HRP)] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 80.66699982 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 226.83399963 m 416.75 226.83399963 l 416.75 258.03399658 l -1.45000005 258.03399658 l h f* Q q 1 0 0 1 0 226.83399963 cm /P <</MCID 44 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 258.03399658 cm /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 285.97299194 cm q /GS2 gs 1 g 0.375 0.75 m 100.42500305 0.75 l 100.42500305 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 101.42500305 -0.25 l 101.42500305 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 48 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 54.72100067 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 101.17500305 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 101.17500305 156.75 l h f* Q q 1 0 0 1 100.80000305 0 cm -0.625 -0.25 m 322.625 -0.25 l 322.625 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 50 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunoglob)1(u)-1(lin)] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 71.82900238 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 76.32900238 11.72200012 Tm [(G)] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 83.02200317 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 87.52200317 11.72200012 Tm [(\(IgG)1(\))] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 108.6289978 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 113.1289978 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 119.69000244 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 124.19000244 11.72200012 Tm [(one)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 140.56399536 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 145.06399536 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 153.90600586 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 158.40600586 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 172.40699768 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 176.90699768 11.72200012 Tm [(most)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 198.58099365 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 203.08099365 11.72200012 Tm [(ab)1(u)-1(nd)1(ant)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 244.52600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 249.02600098 11.72200012 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 284.49899292 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 288.99899292 11.72200012 Tm [(in)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 296.94000244 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 301.44000244 11.72200012 Tm [(ser)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(um)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 13.97900009 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 18.47900009 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 36.875 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 41.375 27.3220005 Tm [(normal)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 71.88200378 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 76.38200378 27.3220005 Tm [(leve)-1(ls)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 100.27500153 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 104.77500153 27.3220005 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 141.84700012 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 146.34700012 27.3220005 Tm [(8-17)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 166.07400513 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 170.57400513 27.3220005 Tm [(mg/mL)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 201.66099548 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 206.16099548 27.3220005 Tm [(in)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 214.102005 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 218.602005 27.3220005 Tm [(ad)1(u)-1(lt)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 240.6269989 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 245.1269989 27.3220005 Tm [(bloo)1(d.)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 272.63699341 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 277.13699341 27.3220005 Tm [(IgG)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 292.23199463 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 296.73199463 27.3220005 Tm [(is)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 303.29299927 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 307.79299927 27.3220005 Tm [(i)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(mpo)1(rtant)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 40.56600189 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 45.06600189 42.92200089 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 57.34400177 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 61.84400177 42.92200089 Tm [(our)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 76.54799652 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 81.04799652 42.92200089 Tm [(defense)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 114.95600128 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 119.45600128 42.92200089 Tm [(ag)1(ainst)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 150.62199402 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 155.12199402 42.92200089 Tm [(mic)-1(r)1(oorg)1(anisms)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 224.21699524 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 228.71699524 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 244.9940033 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 249.4940033 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 263.49499512 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 267.99499512 42.92200089 Tm [(molec)-1(ules)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 311.37799072 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(are)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 13.51799965 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 18.01799965 58.52199936 Tm [(pro)1(duc)-1(ed)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 59.60300064 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 64.10299683 58.52199936 Tm [(by)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 74.61499786 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 79.11499786 58.52199936 Tm [(B)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 84.76200104 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 89.26200104 58.52199936 Tm [(lymphocytes)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 143.76699829 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 148.26699829 58.52199936 Tm [(as)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 157.40800476 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 161.90800476 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 166.88299561 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 171.38299561 58.52199936 Tm [(pa)1(rt)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 188.89500427 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 193.39500427 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 202.23699951 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 206.73699951 58.52199936 Tm [(our)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 221.44099426 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 225.94099426 58.52199936 Tm [(ad)1(apt)1(ive)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 262.97399902 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 267.47399902 58.52199936 Tm [(immun)-1(e)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 302.93301392 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 307.43301392 58.52199936 Tm [(r)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(esponse.)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 37.72700119 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 42.22700119 74.12200165 Tm [(The)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 58.0340004 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 62.5340004 74.12200165 Tm [(IgG)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 77.6289978 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 82.1289978 74.12200165 Tm [(molec)-1(ule)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 121.34600067 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 125.84600067 74.12200165 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 140.52799988 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 145.02799988 74.12200165 Tm [(tw)1(o)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 161.20899963 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 165.70899963 74.12200165 Tm [(separa)1(te)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 202.57499695 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 207.07499695 74.12200165 Tm [(func)-1(t)1(ions,)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 249.147995 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 253.647995 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 262.72299194 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 267.22299194 74.12200165 Tm [(bind)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 286.66900635 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 291.16900635 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 300.24398804 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 304.74398804 74.12200165 Tm [(th)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(e)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 5.10599995 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 9.60599995 89.72200012 Tm [(pa)1(tho)1(gen)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 51.35400009 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 55.85400009 89.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 73.0759964 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 77.5759964 89.72200012 Tm [(eli)-1(cited)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 108.59700012 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 113.09700012 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 127.09799957 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 131.5980072 89.72200012 Tm [(response)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 170.59500122 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 175.09500122 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 191.37199402 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 195.87199402 89.72200012 Tm [(to)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 204.94700623 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 209.44700623 89.72200012 Tm [(rec)-1(ruit)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 237.23399353 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 241.73399353 89.72200012 Tm [(ot)1(her)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 264.89300537 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 269.39300537 89.72200012 Tm [(ce)-1(lls)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 287.96899414 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 292.46899414 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 308.7460022 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(molec)-1(ules)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 43.38299942 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 47.88299942 105.3219986 Tm [(to)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 56.95800018 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 61.45800018 105.3219986 Tm [(dest)1(roy)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 93.76200104 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 98.26200104 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 112.26300049 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 116.76300049 105.3219986 Tm [(antig)1(e)-1(n.)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 151.60699463 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 156.10699463 105.3219986 Tm [(The)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 171.91400146 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 176.41400146 105.3219986 Tm [(var)1(i)-1(a)1(bility)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 217.96899414 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 222.46899414 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 231.31100464 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 235.81100464 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 249.81199646 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 254.31199646 105.3219986 Tm [(IgG)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 269.40701294 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 273.90701294 105.3219986 Tm [(po)1(ol)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 293.49301147 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 297.99301147 105.3219986 Tm [(is)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 304.5539856 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(gene)-1(r)1(ated)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 44.14300156 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 48.64300156 120.92199707 Tm [(by)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 59.15499878 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 63.65499878 120.92199707 Tm [(soma)1(tic)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 97.21199799 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 101.71199799 120.92199707 Tm [(rec)-1(o)1(mbination)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 164.602005 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 169.102005 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 185.3789978 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 189.8789978 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 203.88000488 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 208.38000488 120.92199707 Tm [(number)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 242.19599915 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 246.69599915 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 255.53799438 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 260.03799438 120.92199707 Tm [(speci)-1(f)1(ic)-1(it)1(i)-1(es)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 309.41101074 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(in)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 7.94099998 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 12.44099998 136.52200317 Tm [(an)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 22.96199989 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 27.46199989 136.52200317 Tm [(individual)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 69.34600067 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 73.84600067 136.52200317 Tm [(at)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 82.1740036 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 86.6740036 136.52200317 Tm [(a)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 91.64900208 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 96.14900208 136.52200317 Tm [(given)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 119.67700195 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 124.17700195 136.52200317 Tm [(time)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 143.46499634 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 147.96499634 136.52200317 Tm [(po)1(i)-1(nt)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 170.72900391 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 175.22900391 136.52200317 Tm [(is)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 181.78999329 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 186.28999329 136.52200317 Tm [(estimat)1(e)-1(d)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 228.93499756 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 233.43499756 136.52200317 Tm [(to)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 242.50999451 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 247.00999451 136.52200317 Tm [(be)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 257.86401367 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 262.36401367 136.52200317 Tm [(10)-1(11)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 283.4750061 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 287.9750061 136.52200317 Tm [(var)1(i)-1(a)1(n)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(ts)1(.)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 9.68599987 152.12199402 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 156.75 cm q /GS2 gs 1 g 0.375 0.75 m 100.42500305 0.75 l 100.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 101.42500305 -0.25 l 101.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 259 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations)] TJ ET EMC /P <</MCID 260 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 56.50899887 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 101.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 101.17500305 16.35000038 l h f* Q q 1 0 0 1 100.80000305 0 cm -0.625 -0.25 m 322.625 -0.25 l 322.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 261 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(1/)-1(50)-1(-)1(2)-1(00)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 39.40599823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 43.90599823 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 56.18399811 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 60.68399811 11.72200012 Tm [(most)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 82.35800171 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 86.85800171 11.72200012 Tm [(ap)1(plic)-1(at)1(ion)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 134.62199402 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 100.80000305 0.75 m 100.80000305 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 100.80000305 157.5 m 100.80000305 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.125 m 422.42498779 157.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 173.4750061 m 423.17498779 173.4750061 l S Q Q q 1 0 0 1 0 459.82299805 cm /P <</MCID 269 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 487.76199341 cm /P <</MCID 270 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 515.70098877 cm /P <</MCID 271 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 543.64001465 cm Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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