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[<000B000C000D000E000F>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 149.625 12.82499981 Tm [(IgM)] TJ ET EMC /P <</MCID 8 >> BDC BT 1 0 0 -1 166.19000244 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 97.07800293 cm /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 125.01699829 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Bio)-1(tin)-1(-conj)-1(ugate)1(d)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 139.06900024 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 141.44299316 12.82499981 Tm [(Rabb)-1(it)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 169.13400269 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 171.50799561 12.82499981 Tm [(anti)-1(-hu)-1(man)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 221.16299438 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 223.53700256 12.82499981 Tm [(IgM)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 240.102005 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 152.95599365 cm /P <</MCID 20 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.89500427 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0012000F>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 25 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001300140015>] TJ ET EMC /P <</MCID 26 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 27 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<00160017>] TJ ET EMC /P <</MCID 28 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 208.83399963 cm /P <</MCID 29 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 236.772995 cm /P <</Lang (zh-CN) /MCID 30 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<00180019001A001B000F>] TJ ET EMC /P <</MCID 31 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Bio)-1(tin)] TJ ET EMC /P <</Lang (zh-CN) /MCID 33 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 90.72699738 12.82499981 Tm [<00060007001C0009>] TJ ET EMC /P <</MCID 34 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 132.727005 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 147 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 264.71200562 cm /P <</MCID 36 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 292.65100098 m 416.75 292.65100098 l 416.75 323.85101318 l -1.45000005 323.85101318 l h f* Q q 1 0 0 1 0 292.65100098 cm /P <</MCID 37 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 323.85101318 cm /P <</MCID 40 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 351.79000854 cm q /GS2 gs 1 g 0.375 0.75 m 122.92500305 0.75 l 122.92500305 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 123.92500305 -0.25 l 123.92500305 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 41 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)] TJ ET EMC /P <</MCID 42 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 54.72100067 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 123.67500305 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 123.67500305 172.3500061 l h f* Q q 1 0 0 1 123.30000305 0 cm -0.625 -0.25 m 300.125 -0.25 l 300.125 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 43 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(IgM)] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 17.19599915 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 21.69599915 11.72200012 Tm [(normally)] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 59.36199951 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 63.86199951 11.72200012 Tm [(constitut)1(e)-1(s)] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 111.08100128 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 115.58100128 11.72200012 Tm [(ab)1(out)] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 140.92399597 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 145.42399597 11.72200012 Tm [(10)-1(%)] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 163.98599243 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 168.48599243 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 177.32800293 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 181.82800293 11.72200012 Tm [(serum)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 208.51600647 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 213.01600647 11.72200012 Tm [(immun)-1(o)1(glob)1(u)-1(lins.)] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 290.92700195 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(IgM)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 17.19599915 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 21.69599915 27.3220005 Tm [(antib)1(ody)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 59.95500183 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 64.45500183 27.3220005 Tm [(is)] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 71.01599884 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 75.51599884 27.3220005 Tm [(pro)1(min)-1(ent)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 120.80200195 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 125.30200195 27.3220005 Tm [(in)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 133.24299622 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 137.74299622 27.3220005 Tm [(early)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 158.41900635 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 162.91900635 27.3220005 Tm [(immun)-1(e)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 198.37800598 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 202.87800598 27.3220005 Tm [(responses)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 246.04100037 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 250.54100037 27.3220005 Tm [(to)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 259.61599731 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 264.11599731 27.3220005 Tm [(most)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 285.79000854 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(antig)1(e)-1(ns)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 36.84400177 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 41.34400177 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 57.62099838 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 62.12099838 42.92200089 Tm [(is)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 68.68199921 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 73.18199921 42.92200089 Tm [(larg)1(e)-1(ly)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 102.01000214 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 106.51000214 42.92200089 Tm [(confine)-1(d)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 144.21499634 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 148.71499634 42.92200089 Tm [(to)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 157.78999329 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 162.28999329 42.92200089 Tm [(plas)1(ma)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 192.98100281 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 197.48100281 42.92200089 Tm [(due)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 213.88999939 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 218.38999939 42.92200089 Tm [(to)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 227.46499634 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 231.96499634 42.92200089 Tm [(its)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 241.8789978 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 246.3789978 42.92200089 Tm [(larg)1(e)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 268.04800415 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 272.54800415 42.92200089 Tm [(size.)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 290.80700684 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(Monomeric)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 49.66699982 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 54.16699982 58.52199936 Tm [(IgM)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 71.36299896 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 75.86299896 58.52199936 Tm [(is)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 82.4240036 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 86.9240036 58.52199936 Tm [(expressed)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 130.07800293 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 134.57800293 58.52199936 Tm [(as)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 143.71899414 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 148.21899414 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 153.19400024 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 157.69400024 58.52199936 Tm [(membrane)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 204.47799683 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 208.97799683 58.52199936 Tm [(bo)1(u)-1(nd)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 237.29600525 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 241.79600525 58.52199936 Tm [(antib)1(ody)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 280.05499268 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 284.55499268 58.52199936 Tm [(o)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(n)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 5.546 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 10.04599953 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 24.04700089 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 28.54700089 74.12200165 Tm [(surfa)1(c)-1(e)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 59.40999985 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 63.90999985 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 72.7519989 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 77.2519989 74.12200165 Tm [(B)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 82.89900208 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 87.39900208 74.12200165 Tm [(ce)-1(lls)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 105.97499847 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 110.47499847 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 126.7519989 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 131.2519989 74.12200165 Tm [(as)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 140.39300537 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 144.89300537 74.12200165 Tm [(a)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 149.86799622 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 154.36799622 74.12200165 Tm [(pentamer)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 196.07200623 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 200.57200623 74.12200165 Tm [(wh)1(e)-1(n)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 223.87199402 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 228.37199402 74.12200165 Tm [(sec)-1(reted)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 264.91699219 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 269.41699219 74.12200165 Tm [(by)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 279.9289856 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 284.4289856 74.12200165 Tm [(p)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(lasma)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 24.94300079 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 29.44300079 89.72200012 Tm [(ce)-1(lls.)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 50.18500137 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 54.68500137 89.72200012 Tm [(Due)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 72.19300079 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 76.69300079 89.72200012 Tm [(to)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 85.76799774 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 90.26799774 89.72200012 Tm [(its)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 100.18199921 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 104.68199921 89.72200012 Tm [(hig)1(h)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 123.91699982 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 128.41700745 89.72200012 Tm [(valenc)-1(y)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 160.44000244 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 164.94000244 89.72200012 Tm [(IgM)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 182.13600159 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 186.63600159 89.72200012 Tm [(is)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 193.19700623 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 197.69700623 89.72200012 Tm [(more)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 220.39500427 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 224.89500427 89.72200012 Tm [(efficie)-1(nt)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 259.54998779 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 264.04998779 89.72200012 Tm [(th)1(an)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 283.46499634 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ot)1(her)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 23.1590004 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 27.6590004 105.3219986 Tm [(isot)1(y)-1(p)1(e)-1(s)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 63.07899857 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 67.57900238 105.3219986 Tm [(is)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 74.13999939 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 78.63999939 105.3219986 Tm [(binding)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 111.78399658 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 116.28399658 105.3219986 Tm [(antig)1(e)-1(ns)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 153.12800598 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 157.62800598 105.3219986 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 176.02400208 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 180.52400208 105.3219986 Tm [(repeating)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 221.94700623 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 226.44700623 105.3219986 Tm [(epito)1(pe)-1(s)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 263.79199219 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 268.29199219 105.3219986 Tm [(\(virus)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 291.56500244 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(pa)1(rticle)-1(s)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 36.08800125 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 40.58800125 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 56.86500168 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 61.36500168 120.92199707 Tm [(red)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 75.66500092 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 80.16500092 120.92199707 Tm [(bloo)1(d)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 105.50800323 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 110.00800323 120.92199707 Tm [(ce)-1(lls\))] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 131.58999634 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 136.08999634 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 152.36700439 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 156.86700439 120.92199707 Tm [(is)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 163.42799377 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 167.92799377 120.92199707 Tm [(more)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 190.62600708 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 195.12600708 120.92199707 Tm [(efficie)-1(nt)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 229.78100586 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 234.28100586 120.92199707 Tm [(th)1(an)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 253.69599915 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 258.1960144 120.92199707 Tm [(IgG)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 273.29098511 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 277.79098511 120.92199707 Tm [(in)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 285.73199463 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(activiat)1(in)-1(g)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 44.38000107 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 48.88000107 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 62.88100052 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 67.3809967 136.52200317 Tm [(compleme)-1(nt)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 121.73699951 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 126.23699951 136.52200317 Tm [(pa)1(thw)1(ay.)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 164.86500549 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 169.36500549 136.52200317 Tm [(The)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 185.17199707 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 189.67199707 136.52200317 Tm [(gene)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 211.18800354 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 215.68800354 136.52200317 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 227.96600342 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 232.46600342 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 246.46699524 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 250.96699524 136.52200317 Tm [(mu)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 264.9460144 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 269.4460144 136.52200317 Tm [(cons)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(ta)1(n)-1(t)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 17.22699928 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 21.72699928 152.12199402 Tm [(region)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 49.68899918 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 54.18899918 152.12199402 Tm [(contains)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 90.40399933 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 94.90399933 152.12199402 Tm [(fo)1(u)-1(r)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 112.72799683 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 117.22799683 152.12199402 Tm [(do)1(mains)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 154.22099304 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 158.72099304 152.12199402 Tm [(separa)1(ted)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 201.34399414 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 205.84399414 152.12199402 Tm [(by)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 216.35600281 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 220.85600281 152.12199402 Tm [(sho)1(rt)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 243.07499695 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 247.57499695 152.12199402 Tm [(interven)-1(in)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(g)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 5.75699997 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 10.25699997 167.72200012 Tm [(seque)-1(nce)-1(s)1(.)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 57.43700027 167.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 172.3500061 cm q /GS2 gs 1 g 0.375 0.75 m 122.92500305 0.75 l 122.92500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 123.92500305 -0.25 l 123.92500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 255 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Applic)1(ations)] TJ ET EMC /P <</MCID 256 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 56.50899887 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 123.67500305 0.75 m 422.42498779 0.75 l 422.42498779 31.95000076 l 123.67500305 31.95000076 l h f* Q q 1 0 0 1 123.30000305 0 cm -0.625 -0.25 m 300.125 -0.25 l 300.125 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 257 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Opt)1(imal)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 34.63299942 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 39.13299942 11.72200012 Tm [(test)1(e)-1(d)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 65.97499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 70.47499847 11.72200012 Tm [(ap)1(plic)-1(at)1(ions)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 122.40499878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 126.90499878 11.72200012 Tm [(and)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 143.18200684 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 147.68200684 11.72200012 Tm [(wo)1(rk)-1(ing)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 182.54400635 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 187.04400635 11.72200012 Tm [(dilutions)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 224.31799316 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 228.81799316 11.72200012 Tm [(must)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 250.31599426 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 254.81599426 11.72200012 Tm [(be)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 265.67001343 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 270.17001343 11.72200012 Tm [(dete)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(rmine)-1(d)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 30.67399979 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 35.17399979 27.3220005 Tm [(by)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 45.68600082 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 50.18600082 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 64.18699646 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 68.68699646 27.3220005 Tm [(en)-1(d)] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 85.09600067 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 89.59600067 27.3220005 Tm [(user.)] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 110.01699829 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 123.30000305 0.75 m 123.30000305 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 123.30000305 173.1000061 m 123.30000305 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 172.7250061 m 422.42498779 172.7250061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 204.67500305 m 423.17498779 204.67500305 l S Q Q q 1 0 0 1 0 556.84002686 cm Q Q 1 0 0 -1 0 841.90002441 cm 
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