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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 87 l -90 87 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 76 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 255.94999695 0 0 -74.90000153 0 74.90000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 129.55000305 cm q 1 0 0 1 88 0 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 0 23.67700005 Tm 0 g [(Bi)1(ot)1(in)] TJ ET EMC /P <> BDC BT /FAAABE 22 Tf 1 0 0 -1 59.89799881 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0006>] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 220.01400757 23.67700005 Tm 0 Tr [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.32800293 23.67700005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 41.20000076 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 30.76399994 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 30.76399994 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.75 30.76399994 Tm [(Bio)-1(tin)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 85.47699738 30.76399994 Tm [<0003000400050006000700080006>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 161.602005 30.76399994 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.81399536 30.76399994 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 87.07800293 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 30.76399994 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 30.76399994 Tm [(Bio)-1(tin)-1(-conj)-1(ugate)1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.56900024 30.76399994 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.94299316 30.76399994 Tm [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.30499268 30.76399994 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.67900085 30.76399994 Tm [(anti)-1(-rat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.57400513 30.76399994 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.94799805 30.76399994 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.16000366 30.76399994 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 132.95599365 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 30.76399994 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 30.76399994 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 30.76399994 Tm [<000B000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 30.76399994 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 52.5 30.76399994 Tm [<0010001100120003000400050006000700080006>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 160.125 30.76399994 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.33700562 30.76399994 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 178.83399963 m 416.75 178.83399963 l 416.75 196.83399963 l -1.45000005 196.83399963 l h f* Q q 1 g -1.45000005 196.83399963 m 416.75 196.83399963 l 416.75 214.83399963 l -1.45000005 214.83399963 l h f* Q q 1 g -1.45000005 214.83399963 m 416.75 214.83399963 l 416.75 232.83399963 l -1.45000005 232.83399963 l h f* Q q 1 g -1.45000005 232.83399963 m 416.75 232.83399963 l 416.75 250.83399963 l -1.45000005 250.83399963 l h f* Q q 1 g -1.45000005 250.83399963 m 416.75 250.83399963 l 416.75 282.03399658 l -1.45000005 282.03399658 l h f* Q q 1 0 0 1 0 178.83399963 cm /P <> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 0 15.04699993 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 33.04700089 Tm /GS2 gs 0 g [<001300140015000F000D>] TJ ET EMC /P <> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 52.5 33.04700089 Tm [(Biotin)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 86.625 33.04700089 Tm [<00030004001B0007>] TJ ET EMC /P <> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 128.625 33.04700089 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147 33.04700089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 51.04700089 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 69.04699707 Tm /GS2 gs 0 g [<001C>] TJ ET EMC /P <> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 10.5 69.04699707 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 69.04699707 Tm [<001D000D>] TJ ET EMC /P <> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 42 69.04699707 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 52.5 69.04699707 Tm [<001E001F0020>] TJ ET EMC /P <> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 84 69.04699707 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 99.75 69.04699707 Tm [<00240025>] TJ ET EMC /P <> BDC BT /FAAACG 18 Tf 1 0 0 -1 120.75 69.04699707 Tm 1 Tr 0.51428574 w /GS3 gs 0 G [( )] TJ ET EMC /P <> BDC q /GS3 gs 1 g 0 78.59400177 m 42 78.59400177 l 42 96.60500336 l 0 96.60500336 l h f* Q EMC /P <> BDC BT /FAAADA 10.5 Tf 1 0 0 -1 0 92.17500305 Tm 0 Tr /GS3 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAADE 10.5 Tf 1 0 0 -1 42 92.17500305 Tm /GS4 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 282.03399658 cm q 1 g 0.375 0.75 m 89.52500153 0.75 l 89.52500153 312.75 l 0.375 312.75 l h f* Q q -0.625 -0.25 m 90.52500153 -0.25 l 90.52500153 313.75 l -0.625 313.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADE 10 Tf 1 0 0 -1 0 160.35699463 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)] TJ ET EMC /P <> BDC BT /FAAADI 10 Tf 1 0 0 -1 60.80099869 160.35699463 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 90.27500153 0.75 m 426.17498779 0.75 l 426.17498779 312.75 l 90.27500153 312.75 l h f* Q q 1 0 0 1 89.90000153 0 cm -0.625 -0.25 m 337.2749939 -0.25 l 337.2749939 313.75 l -0.625 313.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADI 10 Tf 1 0 0 -1 0 19.95700073 Tm 0.13333334 g [(Immunoglob)1(u)-1(lin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.80999756 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.80999756 19.95700073 Tm [(G)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.24700165 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.24700165 19.95700073 Tm [(\(IgG)1(\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.6989975 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.6989975 19.95700073 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.98899841 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.98899841 19.95700073 Tm [(one)] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.18200684 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.18200684 19.95700073 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.0059967 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.0059967 19.95700073 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.56300354 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.56300354 19.95700073 Tm [(most)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.64500427 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.64500427 19.95700073 Tm [(ab)1(u)-1(nd)1(ant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.69500732 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 276.69500732 19.95700073 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 316.10900879 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 321.10900879 19.95700073 Tm [(i)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 51.1570015 Tm [(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 6.16200018 51.1570015 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 11.1619997 51.1570015 Tm [(serum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.81499863 51.1570015 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.81499863 51.1570015 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.2539978 51.1570015 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.2539978 51.1570015 Tm [(normal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.15000153 51.1570015 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.15000153 51.1570015 Tm [(leve)-1(ls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.69799805 51.1570015 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.69799805 51.1570015 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.88900757 51.1570015 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.88900757 51.1570015 Tm [(8-17)] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.80799866 51.1570015 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.80799866 51.1570015 Tm [(mg/mL)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.34899902 51.1570015 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.34899902 51.1570015 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 263.17199707 51.1570015 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 268.17199707 51.1570015 Tm [(ad)1(u)-1(lt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 292.64498901 51.1570015 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 297.64498901 51.1570015 Tm [(bloo)1(d.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 328.21099854 51.1570015 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 82.35700226 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.77199936 82.35700226 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.77199936 82.35700226 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.06200027 82.35700226 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.06200027 82.35700226 Tm [(impor)1(tant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.79599762 82.35700226 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.79599762 82.35700226 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.43900299 82.35700226 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.43900299 82.35700226 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.77700043 82.35700226 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.77700043 82.35700226 Tm [(defense)] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.45300293 82.35700226 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.45300293 82.35700226 Tm [(ag)1(ainst)] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.08200073 82.35700226 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.08200073 82.35700226 Tm [(mic)-1(r)1(oorg)1(anisms)] TJ ET EMC /P <> BDC BT 1 0 0 -1 285.85400391 82.35700226 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 290.85400391 82.35700226 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 308.94000244 82.35700226 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 313.94000244 82.35700226 Tm [(th)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 113.55699921 Tm [(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.67399979 113.55699921 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.67399979 113.55699921 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.8769989 113.55699921 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.8769989 113.55699921 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.89700317 113.55699921 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.89700317 113.55699921 Tm [(pro)1(duc)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.10299683 113.55699921 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.10299683 113.55699921 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.78300476 113.55699921 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.78300476 113.55699921 Tm [(B)] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.05700684 113.55699921 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.05700684 113.55699921 Tm [(lymphocytes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.6190033 113.55699921 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.6190033 113.55699921 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 238.7749939 113.55699921 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.7749939 113.55699921 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.30200195 113.55699921 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.30200195 113.55699921 Tm [(pa)1(rt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 273.76000977 113.55699921 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.76000977 113.55699921 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.58401489 113.55699921 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 293.58401489 113.55699921 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 309.92199707 113.55699921 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 314.92199707 113.55699921 Tm [(ad)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 144.75700378 Tm [(ap)1(tive)] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.22400093 144.75700378 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.22399902 144.75700378 Tm [(immun)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.6230011 144.75700378 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.6230011 144.75700378 Tm [(response.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.36000061 144.75700378 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.36000061 144.75700378 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.92300415 144.75700378 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.92300415 144.75700378 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.69500732 144.75700378 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.69500732 144.75700378 Tm [(molec)-1(ule)] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.26899719 144.75700378 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.26899719 144.75700378 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 238.58200073 144.75700378 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.58200073 144.75700378 Tm [(tw)1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.56100464 144.75700378 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.56100464 144.75700378 Tm [(separa)1(te)] TJ ET EMC /P <> BDC BT 1 0 0 -1 307.52301025 144.75700378 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 312.52301025 144.75700378 Tm [(fun)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 175.95700073 Tm [(ctions,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.95700073 175.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.95700073 175.95700073 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.04000092 175.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.04000092 175.95700073 Tm [(bind)] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.64600372 175.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.64600372 175.95700073 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.72899628 175.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.72899628 175.95700073 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.28600311 175.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.28600311 175.95700073 Tm [(pa)1(tho)1(gen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.67300415 175.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.67300415 175.95700073 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.80900574 175.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.80900574 175.95700073 Tm [(eli)-1(cited)] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.2769928 175.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.2769928 175.95700073 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.83399963 175.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.83399963 175.95700073 Tm [(response)] TJ ET EMC /P <> BDC BT 1 0 0 -1 292.16400146 175.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 297.16400146 175.95700073 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 315.25 175.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 320.25 175.95700073 Tm [(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 207.15699768 Tm [(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 6.35699987 207.15699768 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 11.35700035 207.15699768 Tm [(rec)-1(ruit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.23099899 207.15699768 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.23099899 207.15699768 Tm [(ot)1(her)] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.96299744 207.15699768 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.96299744 207.15699768 Tm [(ce)-1(lls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.60299683 207.15699768 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.60299683 207.15699768 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.68900299 207.15699768 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.68900299 207.15699768 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.89199829 207.15699768 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.89199829 207.15699768 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.9750061 207.15699768 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.9750061 207.15699768 Tm [(dest)1(roy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.8690033 207.15699768 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.8690033 207.15699768 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.42599487 207.15699768 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.42599487 207.15699768 Tm [(antig)1(e)-1(n.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 295.14199829 207.15699768 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 300.14199829 207.15699768 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 317.70498657 207.15699768 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 322.70498657 207.15699768 Tm [(v)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 238.35699463 Tm [(aria)1(bility)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.92300034 238.35699463 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.92300034 238.35699463 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.74700165 238.35699463 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.74700165 238.35699463 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.30400085 238.35699463 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.30400085 238.35699463 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.0759964 238.35699463 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.0759964 238.35699463 Tm [(po)1(ol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.83899689 238.35699463 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.83900452 238.35699463 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.1289978 238.35699463 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.1289978 238.35699463 Tm [(gene)-1(r)1(ated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.17700195 238.35699463 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.17700195 238.35699463 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.85699463 238.35699463 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.85699463 238.35699463 Tm [(soma)1(tic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.14199829 238.35699463 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.14199829 238.35699463 Tm [(rec)-1(o)1(mbination)] TJ ET EMC /P <> BDC BT 1 0 0 -1 325.01998901 238.35699463 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 269.55700684 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.08600044 269.55700684 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.08600044 269.55700684 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.64300156 269.55700684 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.64300156 269.55700684 Tm [(number)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.21600342 269.55700684 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.21600342 269.55700684 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.04000092 269.55700684 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.04000092 269.55700684 Tm [(speci)-1(f)1(ic)-1(it)1(i)-1(es)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.897995 269.55700684 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.897995 269.55700684 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.72099304 269.55700684 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.72099304 269.55700684 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.41000366 269.55700684 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.41000366 269.55700684 Tm [(individual)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.94799805 269.55700684 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.94799805 269.55700684 Tm [(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.20100403 269.55700684 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.20098877 269.55700684 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.72799683 269.55700684 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.72799683 269.55700684 Tm [(given)] TJ ET EMC /P <> BDC BT 1 0 0 -1 293.8710022 269.55700684 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 298.8710022 269.55700684 Tm [(time)] TJ ET EMC /P <> BDC BT 1 0 0 -1 320.30200195 269.55700684 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 300.75698853 Tm [(po)1(i)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.29299927 300.75698853 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.29299927 300.75698853 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.58300018 300.75698853 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.58300018 300.75698853 Tm [(estimat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.96600342 300.75698853 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.96600342 300.75698853 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.0490036 300.75698853 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.0490036 300.75698853 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.11000061 300.75698853 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.11000061 300.75698853 Tm [(10)-1(11)] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.56700134 300.75698853 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.56700134 300.75698853 Tm [(var)1(i)-1(a)1(n)-1(t)1(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.27400208 300.75698853 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 312.75 cm q 1 g 0.375 0.75 m 89.52500153 0.75 l 89.52500153 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 90.52500153 -0.25 l 90.52500153 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADE 10 Tf 1 0 0 -1 0 19.95700073 Tm 0.13333334 g [(Applic)1(ations)] TJ ET EMC /P <> BDC BT /FAAADI 10 Tf 1 0 0 -1 62.7879982 19.95700073 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 90.27500153 0.75 m 426.17498779 0.75 l 426.17498779 31.95000076 l 90.27500153 31.95000076 l h f* Q q 1 0 0 1 89.90000153 0 cm -0.625 -0.25 m 337.2749939 -0.25 l 337.2749939 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADI 10 Tf 1 0 0 -1 0 19.95700073 Tm 0.13333334 g [(1/)-1(10)-1(00-50)-1(00)] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.3769989 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.3769989 19.95700073 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.01999664 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.01999664 19.95700073 Tm [(ELISA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.39700317 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.39700317 19.95700073 Tm [(1/)-1(10)-1(00-50)-1(00)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.77400208 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.77400208 19.95700073 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.41700745 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.41700745 19.95700073 Tm [(West)1(e)-1(rn)] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.2749939 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.2749939 19.95700073 Tm [(blot)1(ting)] TJ ET EMC /P <> BDC BT 1 0 0 -1 284.35101318 19.95700073 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 289.35101318 19.95700073 Tm [(1/)-1(10)-1(0-1)] TJ ET EMC Q Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 344.70001221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 89.90000153 0.75 m 89.90000153 312.75 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 89.90000153 313.5 m 89.90000153 344.70001221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.54998779 0.75 m 426.54998779 344.70001221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 313.125 m 426.17498779 313.125 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 345.07501221 m 426.92498779 345.07501221 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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