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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 95.08999634 23.67700005 Tm 0 g [(H1-6)] TJ ET EMC /P <> BDC BT /FAAABE 22 Tf 1 0 0 -1 143.50500488 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 320.20901489 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm [(H1-6)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.40000153 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 88.65000153 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 172.6499939 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(H1-6)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.40000153 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.77400208 12.82499981 Tm [(Antigen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.97599792 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.34999847 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.33000183 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.70399475 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.17799377 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000D000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(H1.6)] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.83599854 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.20999908 12.82499981 Tm [(li)-1(nker)] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.20400238 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.57800293 12.82499981 Tm [(hi)-1(ston)-1(e)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.02600098 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.3999939 12.82499981 Tm [(clu)-1(ste)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.2749939 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.64900208 12.82499981 Tm [(me)1(mb)-1(e)1(r;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.86000061 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.23399353 12.82499981 Tm [(H1t;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.42399597 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.79800415 12.82499981 Tm [(H1.6;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.44400024 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.81799316 12.82499981 Tm [(H1FT)-1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 291.43301392 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 293.80700684 12.82499981 Tm [(HIST)-1(1H1T;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 338.04699707 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 340.42098999 12.82499981 Tm [(dJ221C16.2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 389.46499634 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012001300140011000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019>] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.85800171 12.82499981 Tm [<000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 214.49499512 m 416.75 214.49499512 l 416.75 245.69499207 l -1.45000005 245.69499207 l h f* Q q 1 0 0 1 0 214.49499512 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 21 6.59399986 l 21 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<00030004>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 21 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 245.69500732 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 273.63400269 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.9109993 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.28499985 12.55799961 Tm [(protein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.66699982 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.04100037 12.55799961 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.62599945 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128 12.55799961 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.05400085 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.42799377 12.55799961 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.45799255 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.83200073 12.55799961 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.1230011 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.49699402 12.55799961 Tm [(derive)1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.79200745 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.16600037 12.55799961 Tm [(from)] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.95599365 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.33000183 12.55799961 Tm [(1-207)] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.83200073 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.20599365 12.55799961 Tm [(amin)-1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.08700562 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 290.46099854 12.55799961 Tm [(acid)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 311.9630127 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 314.33700562 12.55799961 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 323.07800293 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 325.45199585 12.55799961 Tm [(hu)-1(man)] TJ ET EMC /P <> BDC BT 1 0 0 -1 355.41900635 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 357.79299927 12.55799961 Tm [(H1-6)] TJ ET EMC /P <> BDC BT /FAAADC 10 Tf 1 0 0 -1 378.19299316 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q /GS2 gs 1 g -1.45000005 302.57299805 m 416.75 302.57299805 l 416.75 333.77301025 l -1.45000005 333.77301025 l h f* Q q 1 0 0 1 0 302.57299805 cm /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 0 20.17499924 Tm [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 333.77301025 m 416.75 333.77301025 l 416.75 364.97302246 l -1.45000005 364.97302246 l h f* Q q 1 0 0 1 0 333.77301025 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0005000600070008>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 364.97299194 cm q /GS2 gs 1 g 0.375 0.75 m 103.42500305 0.75 l 103.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 104.42500305 -0.25 l 104.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 104.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 104.17500305 16.35000038 l h f* Q q 1 0 0 1 103.80000305 0 cm -0.625 -0.25 m 319.625 -0.25 l 319.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(H1)-1(.6)] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.68300056 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.18300056 11.72200012 Tm [(link)-1(er)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.9620018 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.4620018 11.72200012 Tm [(hist)1(one)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.45800018 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.95800018 11.72200012 Tm [(cl)-1(ust)1(e)-1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.47399902 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.97399902 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.23800659 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 103.42500305 0.75 l 103.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 104.42500305 -0.25 l 104.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 104.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 104.17500305 16.35000038 l h f* Q q 1 0 0 1 103.80000305 0 cm -0.625 -0.25 m 319.625 -0.25 l 319.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(H1)-1(t)1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.75799942 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.25799942 11.72200012 Tm [(H1)-1(.6;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.10800171 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.60800171 11.72200012 Tm [(H1)-1(FT;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.95400238 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.45400238 11.72200012 Tm [(HIS)-1(T1H)-1(1T;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.2559967 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.7559967 11.72200012 Tm [(dJ221)-1(C16)-1(.)1(2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.93099976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 103.42500305 0.75 l 103.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 104.42500305 -0.25 l 104.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 104.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 104.17500305 16.35000038 l h f* Q q 1 0 0 1 103.80000305 0 cm -0.625 -0.25 m 319.625 -0.25 l 319.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(P22)-1(49)-1(2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.89599991 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 103.42500305 0.75 l 103.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 104.42500305 -0.25 l 104.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 104.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 104.17500305 16.35000038 l h f* Q q 1 0 0 1 103.80000305 0 cm -0.625 -0.25 m 319.625 -0.25 l 319.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC1)-1(30)-1(35)-1(0)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 103.42500305 0.75 l 103.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 104.42500305 -0.25 l 104.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 104.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 104.17500305 16.35000038 l h f* Q q 1 0 0 1 103.80000305 0 cm -0.625 -0.25 m 319.625 -0.25 l 319.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 103.42500305 0.75 l 103.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 104.42500305 -0.25 l 104.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 104.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 104.17500305 16.35000038 l h f* Q q 1 0 0 1 103.80000305 0 cm -0.625 -0.25 m 319.625 -0.25 l 319.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 103.42500305 0.75 l 103.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 104.42500305 -0.25 l 104.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 104.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 104.17500305 16.35000038 l h f* Q q 1 0 0 1 103.80000305 0 cm -0.625 -0.25 m 319.625 -0.25 l 319.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 103.42500305 0.75 l 103.42500305 141.1499939 l 0.375 141.1499939 l h f* Q q -0.625 -0.25 m 104.42500305 -0.25 l 104.42500305 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 74.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 104.17500305 0.75 m 422.42498779 0.75 l 422.42498779 141.1499939 l 104.17500305 141.1499939 l h f* Q q 1 0 0 1 103.80000305 0 cm -0.625 -0.25 m 319.625 -0.25 l 319.625 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)1(tones)] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.41500092 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.91500092 11.72200012 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.43299866 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.93299866 11.72200012 Tm [(ba)1(sic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.73000336 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.23000336 11.72200012 Tm [(nuc)-1(lear)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.7480011 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.2480011 11.72200012 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.72099304 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.22099304 11.72200012 Tm [(responsib)1(l)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.7559967 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.2559967 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.53399658 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.03399658 11.72200012 Tm [(nuc)-1(leosome)] TJ ET EMC /P <> BDC BT 1 0 0 -1 285.28900146 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 289.78900146 11.72200012 Tm [(st)1(ruc)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ture)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.44199944 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.94199944 27.3220005 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.7840004 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.2840004 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.28499985 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.78499985 27.3220005 Tm [(chromos)1(omal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.84300232 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.34300232 27.3220005 Tm [(fib)1(e)-1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.14900208 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.64900208 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.58999634 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.08999634 27.3220005 Tm [(eu)-1(karyot)1(e)-1(s)1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.33099365 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.83099365 27.3220005 Tm [(Two)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.81799316 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.31799316 27.3220005 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 273.70098877 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.20098877 27.3220005 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 287.04299927 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 291.54299927 27.3220005 Tm [(eac)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.54199982 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.04199982 42.92200089 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.88400078 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.38400078 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.38499832 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.88499832 42.92200089 Tm [(fo)1(u)-1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.70899963 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.20899963 42.92200089 Tm [(core)] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.98699951 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.48699951 42.92200089 Tm [(hist)1(one)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.48300171 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.98300171 42.92200089 Tm [(\(H2)-1(A)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.727005 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.227005 42.92200089 Tm [(H2)-1(B,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.27900696 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.77900696 42.92200089 Tm [(H3)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.18400574 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.68400574 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.96099854 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.46099854 42.92200089 Tm [(H4)-1(\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.70599365 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.20599365 42.92200089 Tm [(fo)1(rm)] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.91699219 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.41699219 42.92200089 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 275.93798828 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 280.43798828 42.92200089 Tm [(octam)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(er,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.70899963 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.20899963 58.52199936 Tm [(aro)1(u)-1(nd)] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.18999863 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.68999863 58.52199936 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.78700256 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.28700256 58.52199936 Tm [(ap)1(prox)1(i)-1(ma)1(tely)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.897995 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.397995 58.52199936 Tm [(14)-1(6)] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.23100281 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.73100281 58.52199936 Tm [(bp)] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.227005 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.727005 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.56900024 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.06900024 58.52199936 Tm [(DNA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.57400513 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.07400513 58.52199936 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.63499451 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.13499451 58.52199936 Tm [(wr)1(app)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.01098633 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 274.51098633 58.52199936 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 282.45199585 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 286.95199585 58.52199936 Tm [(repea)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ting)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.0510006 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.5510006 74.12200165 Tm [(uni)-1(t)1(s,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.72299957 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.22299957 74.12200165 Tm [(calle)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.36399841 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.86399841 74.12200165 Tm [(nuc)-1(leosomes.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.45199585 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.95199585 74.12200165 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.75900269 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.25900269 74.12200165 Tm [(link)-1(er)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.03799438 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.53799438 74.12200165 Tm [(hist)1(one)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.53399658 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.03399658 74.12200165 Tm [(H1)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.43899536 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.93899536 74.12200165 Tm [(interacts)] TJ ET EMC /P <> BDC BT 1 0 0 -1 284.7829895 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 289.2829895 74.12200165 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 307.6789856 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(link)-1(er)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.77899933 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.27899933 89.72200012 Tm [(DNA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.7840004 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.2840004 89.72200012 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.35600281 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.85600281 89.72200012 Tm [(nuc)-1(leosomes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.2769928 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.7769928 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.05400085 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.55400085 89.72200012 Tm [(func)-1(t)1(ions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.46099854 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.96099854 89.72200012 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.9019928 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.4019928 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.40299988 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.90299988 89.72200012 Tm [(compaction)] TJ ET EMC /P <> BDC BT 1 0 0 -1 302.82199097 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.84200001 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.34200001 105.3219986 Tm [(chromat)1(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.25699997 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.75699997 105.3219986 Tm [(into)] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.77300262 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.27300262 105.3219986 Tm [(hig)1(he)-1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.0510025 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.5510025 105.3219986 Tm [(ord)1(e)-1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.00900269 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.50900269 105.3219986 Tm [(st)1(ruc)-1(tures.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.29800415 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.79800415 105.3219986 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.05999756 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.55999756 105.3219986 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.07600403 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.57600403 105.3219986 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.13699341 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.63699341 105.3219986 Tm [(intro)1(n)-1(less)] TJ ET EMC /P <> BDC BT 1 0 0 -1 293.46899414 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 297.96899414 105.3219986 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.75699997 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.25699997 120.92199707 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.17399979 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.67399979 120.92199707 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.64899826 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.14899826 120.92199707 Tm [(replic)-1(a)1(tion-d)1(e)-1(p)1(e)-1(ndent)] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.65299988 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.15299988 120.92199707 Tm [(hist)1(one)] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.98300171 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.48300171 120.92199707 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.70500183 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.20500183 120.92199707 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.76600647 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.26600647 120.92199707 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.24099731 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.74099731 120.92199707 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 276.00500488 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 280.50500488 120.92199707 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 289.34698486 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 293.84698486 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 307.84799194 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(hist)1(one)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.82999992 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.33000183 136.52200317 Tm [(H1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.56900024 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.06900024 136.52200317 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.31700134 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.81700134 136.52200317 Tm [(Transcripts)] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.71099854 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.21099854 136.52200317 Tm [(fro)1(m)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.92199707 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.42199707 136.52200317 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.87800598 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.37800598 136.52200317 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.89399719 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.39399719 136.52200317 Tm [(lack)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.17700195 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.67700195 136.52200317 Tm [(po)1(l)-1(yA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.63800049 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 259.13800049 136.52200317 Tm [(ta)1(il)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 276.42199707 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 280.92199707 136.52200317 Tm [(but)] TJ ET EMC /P <> BDC BT 1 0 0 -1 295.56900024 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 300.06900024 136.52200317 Tm [(in)] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 255.59999084 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 103.80000305 0.75 m 103.80000305 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 103.80000305 17.10000038 m 103.80000305 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 103.80000305 33.45000076 m 103.80000305 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 103.80000305 49.80000305 m 103.80000305 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 103.80000305 66.15000153 m 103.80000305 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 103.80000305 82.5 m 103.80000305 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 103.80000305 98.84999847 m 103.80000305 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 103.80000305 115.19999695 m 103.80000305 255.59999084 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 255.59999084 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 422.42498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 422.42498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 422.42498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 422.42498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 422.42498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 422.42498779 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 422.42498779 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 255.97497559 m 423.17498779 255.97497559 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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