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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 88.70899963 23.67700005 Tm 0 g [(GMFB)] TJ ET EMC /P <</Lang (zh-CN) /MCID 1 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 149.88600159 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 326.58999634 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 3 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 4 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 5 >> BDC BT 1 0 0 -1 63 12.82499981 Tm [(GMFB)] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 89.13700104 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 94.38700104 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 178.38699341 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(GMFB)] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 89.13700104 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 91.51100159 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 124.71299744 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 127.08699799 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 187.06700134 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 189.44099426 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 223.91499329 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 19 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 20 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(gli)-1(a)] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 77.79100037 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 80.16500092 12.82499981 Tm [(maturatio)-1(n)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 128.28700256 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 130.66099548 12.82499981 Tm [(factor,)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 158.66999817 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 161.04400635 12.82499981 Tm [(beta;)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 183.14100647 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 185.51499939 12.82499981 Tm [(GMF)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 205.94099426 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 33 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012001300140011000F>] TJ ET EMC /P <</MCID 34 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 35 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000F>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180005>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019000A>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 214.49499512 m 416.75 214.49499512 l 416.75 245.69499207 l -1.45000005 245.69499207 l h f* Q q 1 0 0 1 0 214.49499512 cm /P <</MCID 46 >> BDC q /GS2 gs 1 g 0 6.59399986 m 21 6.59399986 l 21 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<00030004>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 21 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 245.69500732 cm /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 273.63400269 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 27.9109993 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 30.28499985 12.55799961 Tm [(protein)] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 61.66699982 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 64.04100037 12.55799961 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 125.62599945 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 128 12.55799961 Tm [(to)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 137.05400085 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 139.42799377 12.55799961 Tm [(a)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 144.45799255 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 146.83200073 12.55799961 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 174.1230011 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 176.49699402 12.55799961 Tm [(derive)1(d)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 208.79200745 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 211.16600037 12.55799961 Tm [(from)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 231.95599365 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 234.33000183 12.55799961 Tm [(2-142)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 258.83200073 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 261.20599365 12.55799961 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 288.08700562 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 290.46099854 12.55799961 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 311.9630127 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 314.33700562 12.55799961 Tm [(of)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 323.07800293 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 325.45199585 12.55799961 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 355.41900635 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 357.79299927 12.55799961 Tm [(GMFB)] TJ ET EMC /P <</MCID 77 >> BDC BT /FAAADC 10 Tf 1 0 0 -1 383.92999268 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q /GS2 gs 1 g -1.45000005 302.57299805 m 416.75 302.57299805 l 416.75 333.77301025 l -1.45000005 333.77301025 l h f* Q q 1 0 0 1 0 302.57299805 cm /P <</MCID 78 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 0 20.17499924 Tm [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 333.77301025 m 416.75 333.77301025 l 416.75 364.97302246 l -1.45000005 364.97302246 l h f* Q q 1 0 0 1 0 333.77301025 cm /P <</MCID 79 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 80 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0005000600070008>] TJ ET EMC /P <</MCID 81 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 364.97299194 cm /P <</MCID 82 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 392.9119873 cm q /GS2 gs 1 g 0.375 0.75 m 125.17500305 0.75 l 125.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 126.17500305 -0.25 l 126.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 83 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 86 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 125.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 125.92500305 16.35000038 l h f* Q q 1 0 0 1 125.55000305 0 cm -0.625 -0.25 m 297.875 -0.25 l 297.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 87 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(glia)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 15.52099991 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 20.02099991 11.72200012 Tm [(mat)1(u)-1(r)1(ation)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 67.7539978 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 72.2539978 11.72200012 Tm [(fa)1(c)-1(t)1(or,)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 99.54000092 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 104.04000092 11.72200012 Tm [(beta)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 123.22200012 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 125.17500305 0.75 l 125.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 126.17500305 -0.25 l 126.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 95 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 96 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 125.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 125.92500305 16.35000038 l h f* Q q 1 0 0 1 125.55000305 0 cm -0.625 -0.25 m 297.875 -0.25 l 297.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 97 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(GMF)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 20.26799965 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 125.17500305 0.75 l 125.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 126.17500305 -0.25 l 126.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 99 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 100 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 125.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 125.92500305 16.35000038 l h f* Q q 1 0 0 1 125.55000305 0 cm -0.625 -0.25 m 297.875 -0.25 l 297.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 101 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(P60)-1(98)-1(3)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 31.89599991 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 125.17500305 0.75 l 125.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 126.17500305 -0.25 l 126.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 103 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 106 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 125.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 125.92500305 16.35000038 l h f* Q q 1 0 0 1 125.55000305 0 cm -0.625 -0.25 m 297.875 -0.25 l 297.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 107 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(05)-1(35)-1(9)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 125.17500305 0.75 l 125.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 126.17500305 -0.25 l 126.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 109 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 110 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 125.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 125.92500305 16.35000038 l h f* Q q 1 0 0 1 125.55000305 0 cm -0.625 -0.25 m 297.875 -0.25 l 297.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 111 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 125.17500305 0.75 l 125.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 126.17500305 -0.25 l 126.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 127 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 130 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 125.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 125.92500305 16.35000038 l h f* Q q 1 0 0 1 125.55000305 0 cm -0.625 -0.25 m 297.875 -0.25 l 297.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 131 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 125.17500305 0.75 l 125.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 126.17500305 -0.25 l 126.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 135 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 136 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 125.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 125.92500305 16.35000038 l h f* Q q 1 0 0 1 125.55000305 0 cm -0.625 -0.25 m 297.875 -0.25 l 297.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 137 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 125.17500305 0.75 l 125.17500305 109.94999695 l 0.375 109.94999695 l h f* Q q -0.625 -0.25 m 126.17500305 -0.25 l 126.17500305 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 149 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 58.52199936 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 150 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 58.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 125.92500305 0.75 m 422.42498779 0.75 l 422.42498779 109.94999695 l 125.92500305 109.94999695 l h f* Q q 1 0 0 1 125.55000305 0 cm -0.625 -0.25 m 297.875 -0.25 l 297.875 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 151 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(pro)1(tein)-1(,)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 55.23500061 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 59.73500061 11.72200012 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 84.83200073 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 89.33200073 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 95.89299774 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 100.39299774 11.72200012 Tm [(ph)1(osph)1(orylated)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 168.36799622 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 172.86799622 11.72200012 Tm [(fo)1(l)-1(lo)1(wing)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 213.0249939 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 217.5249939 11.72200012 Tm [(ph)1(orbo)1(l)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 251.83700562 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 256.33700562 11.72200012 Tm [(ester)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 277.50500488 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 282.00500488 11.72200012 Tm [(st)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(imulation,)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 42.92599869 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 47.42599869 27.3220005 Tm [(is)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 53.98699951 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 58.48699951 27.3220005 Tm [(impor)1(tant)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 101.44799805 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 105.94799805 27.3220005 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 118.22599792 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 122.72599792 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 136.727005 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 141.227005 27.3220005 Tm [(ne)-1(r)1(vous)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 175.47399902 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 179.97399902 27.3220005 Tm [(system.)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 212.1289978 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 216.6289978 27.3220005 Tm [(It)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 222.62800598 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 227.12800598 27.3220005 Tm [(cause)-1(s)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 255.6000061 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 260.1000061 27.3220005 Tm [(bra)1(in)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 282.20001221 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 14.40999985 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 18.90999985 42.92200089 Tm [(dif)1(fe)-1(r)1(e)-1(nt)1(i)-1(a)1(tion,)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 82.40200043 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 86.90200043 42.92200089 Tm [(st)1(i)-1(mulat)1(e)-1(s)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 130.78999329 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 135.28999329 42.92200089 Tm [(ne)-1(ura)1(l)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 162.29400635 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 166.79400635 42.92200089 Tm [(regene)-1(ra)1(tion)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 222.27900696 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 226.77900696 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 243.05599976 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 247.55599976 42.92200089 Tm [(inhibits)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 279.0960083 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 283.5960083 42.92200089 Tm [(t)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(umor)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 23.13699913 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 27.63699913 58.52199936 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 42.04700089 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 46.54700089 58.52199936 Tm [(pro)1(life)-1(r)1(ation.)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 102.06300354 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 106.56300354 58.52199936 Tm [(Overexpression)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 173.11799622 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 177.61799622 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 186.46000671 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 190.96000671 58.52199936 Tm [(GMF)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 211.22799683 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 215.72799683 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 223.66900635 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 228.16900635 58.52199936 Tm [(ast)1(rocy)-1(t)1(es)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 271.72299194 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 276.22299194 58.52199936 Tm [(ha)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(s)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 4.16599989 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 8.66600037 74.12200165 Tm [(been)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 30.17300034 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 34.67300034 74.12200165 Tm [(sho)1(wn)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 62.75400162 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 67.2539978 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 76.32900238 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 80.82900238 74.12200165 Tm [(en)-1(h)1(anc)-1(e)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 117.16300201 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 121.66300201 74.12200165 Tm [(bra)1(in)-1(-)1(derived)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 179.93899536 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 184.43899536 74.12200165 Tm [(ne)-1(uro)1(troh)1(ic)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 234.7559967 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 239.2559967 74.12200165 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 264.375 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 268.875 74.12200165 Tm [(\(BD)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(NF\))] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 15.10400009 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 19.60400009 89.72200012 Tm [(pro)1(duc)-1(t)1(ion.)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 69.50800323 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 74.00800323 89.72200012 Tm [(GMF)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 94.27600098 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 98.77600098 89.72200012 Tm [(expression)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 144.72999573 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 149.22999573 89.72200012 Tm [(is)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 155.79100037 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 160.29100037 89.72200012 Tm [(inc)-1(reased)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 201.29200745 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 205.79200745 89.72200012 Tm [(by)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 216.30400085 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 220.80400085 89.72200012 Tm [(exe)-1(r)1(c)-1(ise,)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 257.36199951 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 261.86199951 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 278.13900757 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 282.63900757 89.72200012 Tm [(t)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(he)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 10.64799976 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 15.14799976 105.3219986 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 46.45500183 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 50.95500183 105.3219986 Tm [(is)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 57.51599884 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 62.01599884 105.3219986 Tm [(cru)-1(cial)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 89.78900146 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 94.28900146 105.3219986 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 106.56700134 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 111.06700134 105.3219986 Tm [(exe)-1(r)1(c)-1(ise-induc)-1(t)1(ion)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 190.125 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 194.625 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 203.46699524 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 207.96699524 105.3219986 Tm [(BDNF.)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 234.73399353 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 239.23399353 105.3219986 Tm [(Throug)1(h)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 275.93701172 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 280.43701172 105.3219986 Tm [(B)] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 125.55000305 0.75 m 125.55000305 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 125.55000305 17.10000038 m 125.55000305 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 125.55000305 33.45000076 m 125.55000305 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 125.55000305 49.80000305 m 125.55000305 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 125.55000305 66.15000153 m 125.55000305 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 125.55000305 82.5 m 125.55000305 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 125.55000305 98.84999847 m 125.55000305 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 125.55000305 115.19999695 m 125.55000305 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 422.42498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 422.42498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 422.42498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 422.42498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 422.42498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 422.42498779 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