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EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 66.625 12.82499981 Tm [<0003000400050006000700080009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 142.75 12.82499981 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.96200562 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.33599854 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 102.6780014 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(AP)1(-co)-1(nju)-1(g)1(ated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.96700287 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.34100342 12.82499981 Tm [(Rabb)-1(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.03199768 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.40600586 12.82499981 Tm [(anti)-1(-Goat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.80099487 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.17500305 12.82499981 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.38699341 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 136.21699524 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010001100120013000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(AP)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 66.625 12.82499981 Tm [<0003000400140007>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 108.625 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 169.7559967 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E001700180019>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 97.85800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 118.85800171 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 124.10800171 12.82499981 Tm [<001C001D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 145.10800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 203.29499817 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0003>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(AP)] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 236.83399963 m 416.75 236.83399963 l 416.75 268.03399658 l -1.45000005 268.03399658 l h f* Q q 1 0 0 1 0 236.83399963 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 268.03399658 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 295.97299194 cm q /GS2 gs 1 g 0.375 0.75 m 74.17500305 0.75 l 74.17500305 141.1499939 l 0.375 141.1499939 l h f* Q q -0.625 -0.25 m 75.17500305 -0.25 l 75.17500305 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 74.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 54.72100067 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 74.92500305 0.75 m 422.42498779 0.75 l 422.42498779 141.1499939 l 74.92500305 141.1499939 l h f* Q q 1 0 0 1 74.55000305 0 cm -0.625 -0.25 m 348.875 -0.25 l 348.875 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunoglob)1(u)-1(lin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.82900238 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.32900238 11.72200012 Tm [(G)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.02200317 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.52200317 11.72200012 Tm [(\(IgG)1(\),is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.35600281 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.85600281 11.72200012 Tm [(one)] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.22999573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.72999573 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.57200623 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.07200623 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.07299805 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.57299805 11.72200012 Tm [(most)] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.24699402 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.74699402 11.72200012 Tm [(ab)1(u)-1(nd)1(ant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.19200134 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.69200134 11.72200012 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 282.16500854 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 286.66500854 11.72200012 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 294.60598755 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 299.10598755 11.72200012 Tm [(serum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 325.79400635 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 330.29400635 11.72200012 Tm [(wi)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(th)] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.89500046 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.39500046 27.3220005 Tm [(normal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.90200043 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.40200043 27.3220005 Tm [(leve)-1(ls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.29499817 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.79499817 27.3220005 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.86699677 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.36699677 27.3220005 Tm [(9.5)-1(-)1(1)-1(2.5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.98300171 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.48300171 27.3220005 Tm [(mg/ml)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.34599304 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.84599304 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.78700256 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.28700256 27.3220005 Tm [(ad)1(u)-1(lt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.31199646 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.81199646 27.3220005 Tm [(bloo)1(d.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.32199097 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.82199097 27.3220005 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 276.91699219 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 281.41699219 27.3220005 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 287.97799683 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 292.47799683 27.3220005 Tm [(impor)1(tant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 335.43899536 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.27799988 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.77799988 42.92200089 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.48200035 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.98199844 42.92200089 Tm [(defense)] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.88999939 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.38999939 42.92200089 Tm [(ag)1(ainst)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.55599976 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.05599976 42.92200089 Tm [(mic)-1(r)1(oorg)1(anisms)] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.15100098 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.65100098 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.92799377 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.42799377 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.42900085 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.92900085 42.92200089 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.31201172 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.81201172 42.92200089 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 284.32998657 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.82998657 42.92200089 Tm [(pro)1(duc)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 330.41500854 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 334.91500854 42.92200089 Tm [(b)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 4.76399994 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.26399994 58.52199936 Tm [(B)] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.91100025 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.4109993 58.52199936 Tm [(lymphocytes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.91600037 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.41600037 58.52199936 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.55699921 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.05699921 58.52199936 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.03199768 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.53199768 58.52199936 Tm [(pa)1(rt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.04399872 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.54399872 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.38600159 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.88600159 58.52199936 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.58999634 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.08999634 58.52199936 Tm [(ad)1(apt)1(ive)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.1230011 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.6230011 58.52199936 Tm [(immun)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.08200073 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.58200073 58.52199936 Tm [(response.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.7460022 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 283.2460022 58.52199936 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 299.05300903 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 303.55300903 58.52199936 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 318.64801025 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 323.14801025 58.52199936 Tm [(mol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ec)-1(ule)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.66699982 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.16699982 74.12200165 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.84899902 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.34899902 74.12200165 Tm [(tw)1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.52999878 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.02999878 74.12200165 Tm [(separa)1(te)] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.89600372 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.39600372 74.12200165 Tm [(func)-1(t)1(ions;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.46899414 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.96899414 74.12200165 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.04400635 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.54400635 74.12200165 Tm [(bind)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.99000549 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.49000549 74.12200165 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.56500244 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.06500244 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.06599426 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.56599426 74.12200165 Tm [(pa)1(tho)1(gen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.31399536 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.81399536 74.12200165 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.03601074 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 292.53601074 74.12200165 Tm [(eli)-1(cited)] TJ ET EMC /P <> BDC BT 1 0 0 -1 323.55700684 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 328.05700684 74.12200165 Tm [(th)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.10599995 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.60599995 89.72200012 Tm [(response)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.60300064 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.10300064 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.37999725 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.87999725 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.95500183 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.45500183 89.72200012 Tm [(rec)-1(ruit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.24199677 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.74199677 89.72200012 Tm [(ot)1(her)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.90100098 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.40100098 89.72200012 Tm [(ce)-1(lls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.977005 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.477005 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.7539978 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.2539978 89.72200012 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.63699341 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.13699341 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.21200562 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.71200562 89.72200012 Tm [(dest)1(roy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 285.01599121 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 289.51599121 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 303.51699829 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 308.01699829 89.72200012 Tm [(antig)1(e)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 2.16700006 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 6.66699982 105.3219986 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.47400093 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.97400093 105.3219986 Tm [(var)1(i)-1(a)1(bility)] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.52899933 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.02899933 105.3219986 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.8710022 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.3710022 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.37200165 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.87200165 105.3219986 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.96700287 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.46700287 105.3219986 Tm [(po)1(ol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.05299377 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.55299377 105.3219986 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.11399841 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.61399841 105.3219986 Tm [(gene)-1(r)1(ated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.75700378 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.25700378 105.3219986 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.76899719 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.26899719 105.3219986 Tm [(soma)1(tic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.82598877 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.32598877 105.3219986 Tm [(rec)-1(o)1(mbination)] TJ ET EMC /P <> BDC BT 1 0 0 -1 324.21600342 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 328.71600342 105.3219986 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.75699997 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.25699997 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.25799942 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.75799942 120.92199707 Tm [(number)] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.57400131 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.0739975 120.92199707 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.91600037 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.41600037 120.92199707 Tm [(speci)-1(f)1(ic)-1(it)1(i)-1(es)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.78900146 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.28900146 120.92199707 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.22999573 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.72999573 120.92199707 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.25100708 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.75100708 120.92199707 Tm [(individual)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.63499451 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.13499451 120.92199707 Tm [(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.46299744 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.96299744 120.92199707 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.93800354 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.43800354 120.92199707 Tm [(given)] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.96600342 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.46600342 120.92199707 Tm [(time)] TJ ET EMC /P <> BDC BT 1 0 0 -1 277.7539978 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 282.2539978 120.92199707 Tm [(po)1(i)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 305.01800537 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 309.51800537 120.92199707 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 316.07901001 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 320.57901001 120.92199707 Tm [(esti)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(mat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.62400055 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.12400055 136.52200317 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.19900131 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.69900131 136.52200317 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.5530014 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.0530014 136.52200317 Tm [(10)-1(11)] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.16400146 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.66400146 136.52200317 Tm [(var)1(i)-1(a)1(n)-1(t)1(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.40000153 136.52200317 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 141.1499939 cm q /GS2 gs 1 g 0.375 0.75 m 74.17500305 0.75 l 74.17500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 75.17500305 -0.25 l 75.17500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Applic)1(ations)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 56.50899887 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 74.92500305 0.75 m 422.42498779 0.75 l 422.42498779 31.95000076 l 74.92500305 31.95000076 l h f* Q q 1 0 0 1 74.55000305 0 cm -0.625 -0.25 m 348.875 -0.25 l 348.875 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(1/)-1(20)-1(00-10)-1(00)-1(0)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.51699829 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.01699829 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.29499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.79499817 11.72200012 Tm [(ELISA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.53399658 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.03399658 11.72200012 Tm [(1/)-1(10)-1(00-50)-1(00)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.272995 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.772995 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.05099487 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.55099487 11.72200012 Tm [(West)1(e)-1(rn)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.42399597 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.92399597 11.72200012 Tm [(blot)1(ting)] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.19299316 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.69299316 11.72200012 Tm [(1/)-1(20)-1(0-200)-1(0)] TJ ET EMC /P <> BDC BT 1 0 0 -1 315.6539917 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 320.1539917 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 332.43200684 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 336.93200684 11.72200012 Tm [(I)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(mmunohist)1(oc)-1(h)1(e)-1(mist)1(ry/)-1(cytochemistry)] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.47099304 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 173.09999084 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 74.55000305 0.75 m 74.55000305 141.1499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 74.55000305 141.8999939 m 74.55000305 173.09999084 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 173.09999084 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 141.5249939 m 422.42498779 141.5249939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 173.47499084 m 423.17498779 173.47499084 l S Q Q q 1 0 0 1 0 469.82299805 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 497.76199341 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 525.70098877 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 553.64001465 cm Q Q 1 0 0 -1 0 841.90002441 cm
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