%PDF-1.5 %ÈÈÈÈÈÈ?1 0 obj <> endobj 2 0 obj <>/Metadata 79 0 R>> endobj 3 0 obj <> endobj 4 0 obj <>/ExtGState<>/XObject<>>>/Group<>/StructParents 0/Tabs/S>> endobj 5 0 obj <>stream 1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 269.45001221 0 0 -90.09999847 0 90.09999847 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm q 1 0 0 1 132 0 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 0 23.67700005 Tm 0 g [(AP)] TJ ET EMC /P <> BDC BT /FAAABE 22 Tf 1 0 0 -1 30.54000092 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 190.65600586 23.67700005 Tm 0 Tr [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.97000122 23.67700005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 41.20000076 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 30.76399994 Tm /GS2 gs 0 g [<000A000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 30.76399994 Tm [(AP)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 66.625 30.76399994 Tm [<0003000400050006000700080009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 142.75 30.76399994 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.96200562 30.76399994 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.33599854 30.76399994 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 92.6780014 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(AP)1(-co)-1(nju)-1(g)1(ated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.46700287 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.84100342 12.82499981 Tm [(Goat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.54899597 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.92300415 12.82499981 Tm [(anti)-1(-Ch)-1(icke)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.08999634 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.46400452 12.82499981 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.67599487 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 126.21700287 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0010001100120013000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(AP)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 77.125 12.82499981 Tm [<0003000400140008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 119.125 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 159.7559967 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 193.29499817 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0003>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001C000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(AP)] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 226.83399963 m 416.75 226.83399963 l 416.75 258.03399658 l -1.45000005 258.03399658 l h f* Q q 1 0 0 1 0 226.83399963 cm /P <> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 258.03399658 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 285.97299194 cm q 1 g 0.375 0.75 m 82.42500305 0.75 l 82.42500305 141.1499939 l 0.375 141.1499939 l h f* Q q -0.625 -0.25 m 83.42500305 -0.25 l 83.42500305 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 74.12200165 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 54.72100067 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 83.17500305 0.75 m 422.42498779 0.75 l 422.42498779 141.1499939 l 83.17500305 141.1499939 l h f* Q q 1 0 0 1 82.80000305 0 cm -0.625 -0.25 m 340.625 -0.25 l 340.625 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Immunoglob)1(u)-1(lin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.82900238 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.32900238 11.72200012 Tm [(G)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.02200317 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.52200317 11.72200012 Tm [(\(IgG)1(\),is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.35600281 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.85600281 11.72200012 Tm [(one)] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.22999573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.72999573 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.57200623 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.07200623 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.07299805 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.57299805 11.72200012 Tm [(most)] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.24699402 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.74699402 11.72200012 Tm [(ab)1(u)-1(nd)1(ant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.19200134 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.69200134 11.72200012 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 282.16500854 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 286.66500854 11.72200012 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 294.60598755 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 299.10598755 11.72200012 Tm [(serum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 325.79400635 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.39599991 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.89599991 27.3220005 Tm [(normal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.40299988 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.90299988 27.3220005 Tm [(leve)-1(ls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.79599762 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.29599762 27.3220005 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.36799622 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.86799622 27.3220005 Tm [(9.5)-1(-)1(1)-1(2.5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.48399353 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.98399353 27.3220005 Tm [(mg/ml)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.84700012 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.34700012 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.28799438 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.78799438 27.3220005 Tm [(ad)1(u)-1(lt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.81300354 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.31300354 27.3220005 Tm [(bloo)1(d.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.82299805 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.32299805 27.3220005 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 286.41799927 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 290.91799927 27.3220005 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 297.47900391 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 301.97900391 27.3220005 Tm [(impor)1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.8739996 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.37400055 42.92200089 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.65200043 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.15200043 42.92200089 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.85599899 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.35599899 42.92200089 Tm [(defense)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.26399994 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.76399994 42.92200089 Tm [(ag)1(ainst)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.93000031 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.42999268 42.92200089 Tm [(mic)-1(r)1(oorg)1(anisms)] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.5249939 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.0249939 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.30200195 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.80200195 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.80299377 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.30299377 42.92200089 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 284.68600464 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 289.18600464 42.92200089 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 302.70401001 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 307.20401001 42.92200089 Tm [(pro)1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(uc)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.92200089 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.42200089 58.52199936 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.93399811 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.43399811 58.52199936 Tm [(B)] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.08100128 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.58100128 58.52199936 Tm [(lymphocytes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.08599854 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.58599854 58.52199936 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.72699738 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.22699738 58.52199936 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.20199585 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.70199585 58.52199936 Tm [(pa)1(rt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.21400452 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.71400452 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.55599976 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.05599976 58.52199936 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.75999451 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.25999451 58.52199936 Tm [(ad)1(apt)1(ive)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.29299927 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.79299927 58.52199936 Tm [(immun)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.25201416 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 268.75201416 58.52199936 Tm [(response.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 309.91598511 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 314.41598511 58.52199936 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 330.22299194 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.09500027 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.59499931 74.12200165 Tm [(molec)-1(ule)] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.81200027 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.31200027 74.12200165 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.9940033 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.4940033 74.12200165 Tm [(tw)1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.67500305 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.17500305 74.12200165 Tm [(separa)1(te)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.04100037 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.54100037 74.12200165 Tm [(func)-1(t)1(ions;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.61399841 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.11399841 74.12200165 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.18899536 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.68899536 74.12200165 Tm [(bind)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.13499451 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.63499451 74.12200165 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.71000671 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.21000671 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.21099854 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.71099854 74.12200165 Tm [(pa)1(tho)1(gen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 302.45901489 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 306.95901489 74.12200165 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 324.18099976 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(eli)-1(cited)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.02099991 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.52099991 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.52199936 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.02199936 89.72200012 Tm [(response)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.01899719 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.51899719 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.79599762 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.29599762 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.3710022 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.8710022 89.72200012 Tm [(rec)-1(ruit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.65800476 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.15800476 89.72200012 Tm [(ot)1(her)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.31700134 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.81700134 89.72200012 Tm [(ce)-1(lls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.39300537 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.89300537 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.16999817 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.66999817 89.72200012 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 279.05300903 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 283.55300903 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 292.62799072 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 297.12799072 89.72200012 Tm [(dest)1(roy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 329.43200684 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.0010004 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.50099945 105.3219986 Tm [(antig)1(e)-1(n.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.34500122 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.84500122 105.3219986 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.65200043 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.15200043 105.3219986 Tm [(var)1(i)-1(a)1(bility)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.70700073 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.20700073 105.3219986 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.04899597 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.54899597 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.55000305 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.05000305 105.3219986 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.14500427 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.64500427 105.3219986 Tm [(po)1(ol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.23100281 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.73100281 105.3219986 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.29200745 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.79200745 105.3219986 Tm [(gene)-1(r)1(ated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.93499756 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 259.43499756 105.3219986 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.94699097 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 274.44699097 105.3219986 Tm [(soma)1(tic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 308.0039978 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 312.5039978 105.3219986 Tm [(rec)-1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(mbinat)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.11199951 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.61199951 120.92199707 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.88899994 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.38899994 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.38999939 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.88999939 120.92199707 Tm [(number)] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.70600128 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.20600128 120.92199707 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.04800415 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.54800415 120.92199707 Tm [(speci)-1(f)1(ic)-1(it)1(i)-1(es)] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.92100525 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.42100525 120.92199707 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.36199951 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.86199951 120.92199707 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.38299561 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.88299561 120.92199707 Tm [(individual)] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.76699829 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.26699829 120.92199707 Tm [(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 275.59500122 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 280.09500122 120.92199707 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 285.07000732 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 289.57000732 120.92199707 Tm [(given)] TJ ET EMC /P <> BDC BT 1 0 0 -1 313.09799194 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 317.59799194 120.92199707 Tm [(tim)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.10599995 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.60599995 136.52200317 Tm [(po)1(i)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.36999893 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.86999893 136.52200317 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.43099976 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.93099976 136.52200317 Tm [(estimat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.5759964 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.0759964 136.52200317 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.15100098 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.65100098 136.52200317 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.50499725 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.00499725 136.52200317 Tm [(10)-1(11)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.11599731 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.61599731 136.52200317 Tm [(var)1(i)-1(a)1(n)-1(t)1(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.352005 136.52200317 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 141.1499939 cm q 1 g 0.375 0.75 m 82.42500305 0.75 l 82.42500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 83.42500305 -0.25 l 83.42500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 19.52199936 Tm 0.13333334 g [(Applic)1(ations)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 56.50899887 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 83.17500305 0.75 m 422.42498779 0.75 l 422.42498779 31.95000076 l 83.17500305 31.95000076 l h f* Q q 1 0 0 1 82.80000305 0 cm -0.625 -0.25 m 340.625 -0.25 l 340.625 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(1/)-1(10)-1(00-50)-1(00)] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.23899841 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.73899841 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.01699829 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.51699829 11.72200012 Tm [(ELISA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.2559967 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.7559967 11.72200012 Tm [(1/)-1(10)-1(00-50)-1(00)] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.99499512 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.49499512 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.772995 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.272995 11.72200012 Tm [(West)1(e)-1(rn)] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.14599609 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.64599609 11.72200012 Tm [(blot)1(ting)] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.91499329 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.41500854 11.72200012 Tm [(1/)-1(20)-1(0-500)] TJ ET EMC /P <> BDC BT 1 0 0 -1 305.09899902 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 309.59899902 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 321.87701416 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 326.37701416 11.72200012 Tm [(I)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(mmunohist)1(oc)-1(h)1(e)-1(mist)1(ry/)-1(cytochemistry)] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.47099304 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 173.09999084 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 82.80000305 0.75 m 82.80000305 141.1499939 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 82.80000305 141.8999939 m 82.80000305 173.09999084 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 173.09999084 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 141.5249939 m 422.42498779 141.5249939 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 173.47499084 m 423.17498779 173.47499084 l S Q Q q 1 0 0 1 0 459.82299805 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 487.76199341 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 515.70098877 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 543.64001465 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 571.57897949 cm Q Q 1 0 0 -1 0 841.90002441 cm endstream endobj 6 0 obj <>stream ºÝºÝÈÈÔÚÏßÊÓÆµÃâ·Ñ <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| 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