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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 81.85600281 23.67700005 Tm 0 g [(GHITM)] TJ ET EMC /P <</MCID 1 >> BDC BT 1 0 0 -1 145.74000549 23.67700005 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 2 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 156.74000549 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 3 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 333.44400024 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 4 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 63 12.82499981 Tm [(GHITM)] TJ ET EMC /P <</MCID 7 >> BDC BT 1 0 0 -1 92.90599823 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 98.15599823 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 182.15600586 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(GHITM)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 92.90599823 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 95.27999878 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 128.48199463 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 130.85600281 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 190.83599854 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 193.21000671 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 227.68400574 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(gr)1(o)-1(wt)1(h)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 93.68000031 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 100.36299896 12.82499981 Tm [(ho)-1(r)1(mo)-1(ne)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 139.74299622 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 146.42599487 12.82499981 Tm [(in)-1(du)-1(cibl)-1(e)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 185.38600159 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 192.06900024 12.82499981 Tm [(transme)1(mb)-1(r)1(an)-1(e)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 260.84698486 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 267.52999878 12.82499981 Tm [(protein)-1(;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 301.72198486 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 308.40499878 12.82499981 Tm [(DE)-1(R)1(P2;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 339.24899292 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 345.93200684 12.82499981 Tm [(MICS)-1(1)1(;)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 376.10900879 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 382.79199219 12.82499981 Tm [(My0)1(21;)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 415.29699707 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 0 30.49699783 Tm [(PTD010;)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 35.77600098 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 38.15000153 30.49699783 Tm [(TMBIM5;)] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 77.70999908 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 80.08399963 30.49699783 Tm [(HS)-1(P)1(C282)] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 118.43900299 30.49699783 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 165.35600281 cm /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 198.89500427 cm /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 232.43400574 cm /P <</Lang (zh-CN) /MCID 59 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001A>-4<001B>] TJ ET EMC /P <</MCID 60 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 21.08399963 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 260.37298584 cm /P <</MCID 61 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 288.31201172 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 62 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 27.9109993 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 30.28499985 12.55799961 Tm [(protein)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 61.66699982 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 64.04100037 12.55799961 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 125.62599945 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 128 12.55799961 Tm [(to)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 137.05400085 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 139.42799377 12.55799961 Tm [(C)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 145.0269928 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 147.40100098 12.55799961 Tm [(ter)1(min)-1(al)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 183.55599976 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 185.92999268 12.55799961 Tm [(53)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 196.57400513 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 198.94799805 12.55799961 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 225.82899475 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 228.20300293 12.55799961 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 249.70500183 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 252.07899475 12.55799961 Tm [(of)] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 260.82000732 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 263.19400024 12.55799961 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 293.16101074 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 295.53500366 12.55799961 Tm [(GHITM)] TJ ET EMC /P <</MCID 85 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 325.44100952 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 317.25100708 cm /P <</MCID 86 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 345.19000244 cm /P <</Lang (zh-CN) /MCID 87 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001C>-4<001D>-4<001E>-4<001F>] TJ ET EMC /P <</MCID 88 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 42.16799927 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 373.1289978 cm /P <</MCID 89 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 401.06799316 cm q /GS2 gs 1 g 0.375 0.75 m 100.42500305 0.75 l 100.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 101.42500305 -0.25 l 101.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 90 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 93 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 101.17500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 101.17500305 16.35000038 l h f* Q q 1 0 0 1 100.80000305 0 cm -0.625 -0.25 m 326.375 -0.25 l 326.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 94 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(gr)1(owt)1(h)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 30.91600037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 35.41600037 11.72200012 Tm [(ho)1(rmone)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 74.92299652 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 79.42299652 11.72200012 Tm [(induc)-1(ib)1(l)-1(e)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 118.8239975 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 123.3239975 11.72200012 Tm [(tr)1(ansme)-1(mb)1(rane)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 191.58399963 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 196.08399963 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 227.39100647 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 100.42500305 0.75 l 100.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 101.42500305 -0.25 l 101.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 104 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 105 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 101.17500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 101.17500305 16.35000038 l h f* Q q 1 0 0 1 100.80000305 0 cm -0.625 -0.25 m 326.375 -0.25 l 326.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 106 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(DER)1(P2)-1(;)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 30.62999916 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 35.13000107 11.72200012 Tm [(MICS1)-1(;)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 65.22799683 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 69.72799683 11.72200012 Tm [(My0)-1(21)-1(;)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 101.28500366 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 105.78500366 11.72200012 Tm [(PTD01)-1(0;)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 141.30599976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 145.80599976 11.72200012 Tm [(TMB)-1(IM5;)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 184.28900146 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 188.78900146 11.72200012 Tm [(HS)-1(P)1(C2)-1(82)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 228.30499268 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 100.42500305 0.75 l 100.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 101.42500305 -0.25 l 101.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 118 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 119 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 101.17500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 101.17500305 16.35000038 l h f* Q q 1 0 0 1 100.80000305 0 cm -0.625 -0.25 m 326.375 -0.25 l 326.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 120 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q9H)-1(3K2)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 35.84199905 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 100.42500305 0.75 l 100.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 101.42500305 -0.25 l 101.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 122 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 125 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 101.17500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 101.17500305 16.35000038 l h f* Q q 1 0 0 1 100.80000305 0 cm -0.625 -0.25 m 326.375 -0.25 l 326.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 126 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(10)-1(35)-1(4)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 100.42500305 0.75 l 100.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 101.42500305 -0.25 l 101.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 128 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 129 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 101.17500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 101.17500305 16.35000038 l h f* Q q 1 0 0 1 100.80000305 0 cm -0.625 -0.25 m 326.375 -0.25 l 326.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 130 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 100.42500305 0.75 l 100.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 101.42500305 -0.25 l 101.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 146 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 149 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 101.17500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 101.17500305 16.35000038 l h f* Q q 1 0 0 1 100.80000305 0 cm -0.625 -0.25 m 326.375 -0.25 l 326.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 150 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 100.42500305 0.75 l 100.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 101.42500305 -0.25 l 101.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 154 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 155 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 101.17500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 101.17500305 16.35000038 l h f* Q q 1 0 0 1 100.80000305 0 cm -0.625 -0.25 m 326.375 -0.25 l 326.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 156 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 100.42500305 0.75 l 100.42500305 63.15000153 l 0.375 63.15000153 l h f* Q q -0.625 -0.25 m 101.42500305 -0.25 l 101.42500305 64.15000153 l -0.625 64.15000153 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 168 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 35.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 169 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 35.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 101.17500305 0.75 m 426.17498779 0.75 l 426.17498779 63.15000153 l 101.17500305 63.15000153 l h f* Q q 1 0 0 1 100.80000305 0 cm -0.625 -0.25 m 326.375 -0.25 l 326.375 64.15000153 l -0.625 64.15000153 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 170 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gr)1(owt)1(h)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 31.85199928 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 36.35200119 11.72200012 Tm [(ho)1(rmone)-1(-)1(in)-1(d)1(uc)-1(ible)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 119.15399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 123.65399933 11.72200012 Tm [(tr)1(ansme)-1(mb)1(rane)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 191.91400146 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 196.41400146 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 227.72099304 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 232.22099304 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 238.78199768 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 243.28199768 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 248.25700378 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 252.75700378 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 284.06399536 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 288.56399536 11.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 305.78601074 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 310.28601074 11.72200012 Tm [(in)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 318.22698975 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(humans)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 34.20700073 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 38.70700073 27.3220005 Tm [(is)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 45.26800156 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 49.76800156 27.3220005 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 87.27500153 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 91.77500153 27.3220005 Tm [(by)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 102.28700256 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 106.78700256 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 120.78800201 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 125.28800201 27.3220005 Tm [(GHITM)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 155.53999329 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 160.03999329 27.3220005 Tm [(gene)-1(.)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 183.72200012 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 188.22200012 27.3220005 Tm [(Required)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 227.20100403 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 231.70100403 27.3220005 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 243.97900391 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 248.47900391 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 262.48001099 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 266.98001099 27.3220005 Tm [(mito)1(c)-1(ho)1(n)-1(d)1(r)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ial)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 9.76500034 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 14.26500034 42.92200089 Tm [(tub)1(u)-1(la)1(r)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 45.26399994 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 49.76399994 42.92200089 Tm [(ne)-1(t)1(wo)1(rk)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 84.93299866 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 89.43299866 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 105.70999908 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 110.20999908 42.92200089 Tm [(cristae)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 138.15499878 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 142.65499878 42.92200089 Tm [(org)1(anizat)1(ion.)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 199.06799316 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 203.56799316 42.92200089 Tm [(Involved)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 240.18800354 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 244.68800354 42.92200089 Tm [(in)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 252.6289978 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 257.1289978 42.92200089 Tm [(ap)1(opt)1(otic)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 298.65701294 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 303.15701294 42.92200089 Tm [(rel)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ease)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 19.35400009 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 23.85400009 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 32.69599915 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 37.19599915 58.52199936 Tm [(cy)-1(t)1(oc)-1(h)1(rome)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 88.30000305 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 92.80000305 58.52199936 Tm [(c.)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 99.48000336 58.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 177.6000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 100.80000305 0.75 m 100.80000305 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 100.80000305 17.10000038 m 100.80000305 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 100.80000305 33.45000076 m 100.80000305 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 100.80000305 49.80000305 m 100.80000305 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 100.80000305 66.15000153 m 100.80000305 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 100.80000305 82.5 m 100.80000305 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 100.80000305 98.84999847 m 100.80000305 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 100.80000305 115.19999695 m 100.80000305 177.6000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.54998779 0.75 m 426.54998779 177.6000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17498779 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 426.17498779 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 177.9750061 m 426.92498779 177.9750061 l S Q Q q 1 0 0 1 0 579.41802979 cm Q Q 1 0 0 -1 0 841.90002441 cm 
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