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1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000A000B000C000D000E>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 57.75 12.82499981 Tm [<000300040005>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 91.875 12.82499981 Tm [(TUBB\(HRP-Con)-1(jugate\))] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 185.79600525 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 238.29600525 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 243.54600525 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 57.75 12.82499981 Tm [(Anti-)-1(TUB)1(B\()-1(HRP)1(-C)-1(onj)-1(ugate)1(\))] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 172.40400696 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 174.77799988 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 203.55000305 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 205.92399597 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 256.24499512 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 258.61898804 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 296.41500854 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000C000E>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(tub)-1(ul)-1(in)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 93.40299988 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 95.77700043 12.82499981 Tm [(beta)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 115.06500244 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 117.43900299 12.82499981 Tm [(class)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 137.53199768 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 139.90600586 12.82499981 Tm [(I;)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 145.36099243 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 147.73500061 12.82499981 Tm [(M40;)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 170.16499329 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 172.53900146 12.82499981 Tm [(TUBB1;)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 203.94700623 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 206.32099915 12.82499981 Tm [(TUBB5;)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 237.72900391 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 240.10299683 12.82499981 Tm [(CDC)-1(BM6)1(;)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 280.57998657 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 282.95401001 12.82499981 Tm [(CS)-1(CSC)-1(1)1(;)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 317.52999878 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 319.9039917 12.82499981 Tm [(OK/SW-cl.)-1(56)] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 373.89099121 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011001200130010000E>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<0014001500050009>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 105 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0016>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0017000E>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00180019001A>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001B001C>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000E>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TUBB\(HRP-Con)-1(jugate\))] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 156.92100525 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 159.29499817 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001F000E>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 72 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0020002100220023000E>] TJ ET EMC /P <</MCID 73 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)1(,)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 130.96800232 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 133.34199524 12.82499981 Tm [(Mon)-1(k)1(ey,)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 170.74299622 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 173.11700439 12.82499981 Tm [(Hamster)1(,)] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 212.20500183 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 214.57899475 12.82499981 Tm [(Rat)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 228.82699585 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 84 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0024>] TJ ET EMC /P <</MCID 85 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 86 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0025>] TJ ET EMC /P <</MCID 87 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 88 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0026000E>] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(HRP)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 80.66699982 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 92 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS2 gs 0 g [<0007000800130027>] TJ ET EMC /P <</MCID 93 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 126 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 147 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 176.36199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 178.73599243 12.82499981 Tm [(Mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 229.64700317 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 348.65100098 m 416.75 348.65100098 l 416.75 379.85101318 l -1.45000005 379.85101318 l h f* Q q 1 0 0 1 0 348.65100098 cm /P <</MCID 98 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 99 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 100 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 379.85101318 cm /P <</MCID 101 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 407.79000854 cm q /GS2 gs 1 g 0.375 0.75 m 176.17500305 0.75 l 176.17500305 125.55000305 l 0.375 125.55000305 l h f* Q q -0.625 -0.25 m 177.17500305 -0.25 l 177.17500305 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 102 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 66.3219986 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 103 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 66.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 176.92500305 0.75 m 422.42498779 0.75 l 422.42498779 125.55000305 l 176.92500305 125.55000305 l h f* Q q 1 0 0 1 176.55000305 0 cm -0.625 -0.25 m 246.875 -0.25 l 246.875 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 104 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(beta)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 116.85199738 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 121.35199738 11.72200012 Tm [(tub)1(u)-1(lin)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 151.8809967 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 156.3809967 11.72200012 Tm [(pro)1(tein)-1(.)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 189.85400391 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 194.35400391 11.72200012 Tm [(This)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 211.61599731 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 216.11599731 11.72200012 Tm [(pro)1(t)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ein)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 13.04699993 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 17.54700089 27.3220005 Tm [(fo)1(rms)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 42.42399979 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 46.92399979 27.3220005 Tm [(a)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 51.89899826 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 56.39899826 27.3220005 Tm [(dimer)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 81.52700043 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 86.02700043 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 104.42299652 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 108.92299652 27.3220005 Tm [(alph)1(a)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 132.55700684 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 137.05700684 27.3220005 Tm [(tub)1(u)-1(lin)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 167.58599854 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 172.08599854 27.3220005 Tm [(and)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 188.36300659 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 192.86300659 27.3220005 Tm [(acts)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 209.86999512 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 214.36999512 27.3220005 Tm [(as)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 223.51100159 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 228.01100159 27.3220005 Tm [(a)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 232.98599243 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(st)1(ruc)-1(tura)1(l)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 40.72000122 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 45.22000122 42.92200089 Tm [(component)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 94.90899658 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 99.40899658 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 108.25099945 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 112.75099945 42.92200089 Tm [(mic)-1(r)1(otubules.)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 171.2769928 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 175.7769928 42.92200089 Tm [(Mutat)1(ions)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 219.62600708 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 224.12600708 42.92200089 Tm [(in)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 232.06700134 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(th)1(is)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 15.45600033 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 19.95599937 58.52199936 Tm [(gene)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 41.47200012 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 45.97200012 58.52199936 Tm [(cause)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 70.27799988 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 74.77799988 58.52199936 Tm [(cortical)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 106.08000183 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 110.58000183 58.52199936 Tm [(dyspla)1(sia,)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 152.08599854 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 156.58599854 58.52199936 Tm [(complex,)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 195.23199463 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 199.73199463 58.52199936 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 218.12800598 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 222.62800598 58.52199936 Tm [(ot)1(h)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(er)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 8.54300022 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 13.04300022 74.12200165 Tm [(bra)1(in)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 35.14300156 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 39.64300156 74.12200165 Tm [(malfo)1(rmat)1(i)-1(o)1(ns)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 102.31300354 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 106.81300354 74.12200165 Tm [(6.)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 114.25700378 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 118.75700378 74.12200165 Tm [(Alt)1(e)-1(rna)1(tive)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 165.47999573 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 169.97999573 74.12200165 Tm [(splicin)-1(g)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 202.89500427 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 207.39500427 74.12200165 Tm [(results)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 235.56399536 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(in)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 7.94099998 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 12.44099998 89.72200012 Tm [(multiple)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 47.81299973 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 52.31299973 89.72200012 Tm [(splice)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 76.63700104 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 81.13700104 89.72200012 Tm [(var)1(i)-1(a)1(n)-1(t)1(s.)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 116.8730011 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 121.3730011 89.72200012 Tm [(There)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 145.7230072 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 150.2230072 89.72200012 Tm [(are)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 163.74099731 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 168.24099731 89.72200012 Tm [(multiple)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 203.61300659 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 208.11300659 89.72200012 Tm [(pseud)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(og)1(e)-1(nes)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 31.40299988 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 35.90299988 105.3219986 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 48.18099976 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 52.68099976 105.3219986 Tm [(th)1(is)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 68.13700104 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 72.63700104 105.3219986 Tm [(gene)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 94.15299988 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 98.65299988 105.3219986 Tm [(on)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 109.92099762 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 114.42099762 105.3219986 Tm [(chromos)1(ome)-1(s)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 175.38200378 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 179.88200378 105.3219986 Tm [(1,)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 187.32600403 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 191.82600403 105.3219986 Tm [(6,)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 199.27000427 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 203.77000427 105.3219986 Tm [(7,)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 211.21400452 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 215.71400452 105.3219986 Tm [(8,)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 223.15800476 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 227.65800476 105.3219986 Tm [(9,)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 235.102005 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 16.27700043 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 20.77700043 120.92199707 Tm [(13)-1(.)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 33.49900055 120.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 125.55000305 cm q /GS2 gs 1 g 0.375 0.75 m 176.17500305 0.75 l 176.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 177.17500305 -0.25 l 177.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 225 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 226 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 176.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 176.92500305 16.35000038 l h f* Q q 1 0 0 1 176.55000305 0 cm -0.625 -0.25 m 246.875 -0.25 l 246.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 227 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 14.80500031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 141.8999939 cm q /GS2 gs 1 g 0.375 0.75 m 176.17500305 0.75 l 176.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 177.17500305 -0.25 l 177.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 229 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 234 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 176.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 176.92500305 16.35000038 l h f* Q q 1 0 0 1 176.55000305 0 cm -0.625 -0.25 m 246.875 -0.25 l 246.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 235 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(TUBB)-1(\(HRP-)1(Conju)-1(g)1(ate\))] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 95.84899902 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 158.25 cm q /GS2 gs 1 g 0.375 0.75 m 176.17500305 0.75 l 176.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 177.17500305 -0.25 l 177.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 237 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 238 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 176.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 176.92500305 16.35000038 l h f* Q q 1 0 0 1 176.55000305 0 cm -0.625 -0.25 m 246.875 -0.25 l 246.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 239 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Fusion)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 28.15600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 32.65599823 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 63.96300125 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 68.46299744 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 77.30500031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 81.80500031 11.72200012 Tm [(human)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 111.84600067 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 116.34600067 11.72200012 Tm [(TUBB)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 139.51800537 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 174.6000061 cm q /GS2 gs 1 g 0.375 0.75 m 176.17500305 0.75 l 176.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 177.17500305 -0.25 l 177.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 249 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 252 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 176.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 176.92500305 16.35000038 l h f* Q q 1 0 0 1 176.55000305 0 cm -0.625 -0.25 m 246.875 -0.25 l 246.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 253 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(tub)1(u)-1(lin)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 30.52899933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 35.02899933 11.72200012 Tm [(beta)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 54.21099854 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 58.71099854 11.72200012 Tm [(cl)-1(a)1(ss)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 78.9260025 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 83.4260025 11.72200012 Tm [(I)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 86.0719986 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 190.94999695 cm q /GS2 gs 1 g 0.375 0.75 m 176.17500305 0.75 l 176.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 177.17500305 -0.25 l 177.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 261 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 262 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 176.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 176.92500305 16.35000038 l h f* Q q 1 0 0 1 176.55000305 0 cm -0.625 -0.25 m 246.875 -0.25 l 246.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 263 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(M40)-1(;)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 21.51600075 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 26.01600075 11.72200012 Tm [(TUBB)-1(1;)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 56.63299942 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 61.13299942 11.72200012 Tm [(TUBB)-1(5;)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 91.75 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 96.25 11.72200012 Tm [(CDCBM6)-1(;)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 137.03100586 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 141.53100586 11.72200012 Tm [(CSCSC1)-1(;)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 177.42599487 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 181.92599487 11.72200012 Tm [(OK/SW-)1(c)-1(l.56)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 236.69500732 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 207.30003357 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 176.55000305 0.75 m 176.55000305 125.55000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 176.55000305 126.30000305 m 176.55000305 141.90000916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 176.55000305 142.65000916 m 176.55000305 158.25001526 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 176.55000305 159.00001526 m 176.55000305 174.60002136 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 176.55000305 175.35002136 m 176.55000305 190.95002747 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 176.55000305 191.70002747 m 176.55000305 207.30003357 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 207.30003357 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 125.92500305 m 422.42498779 125.92500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 142.27500916 m 422.42498779 142.27500916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 158.62501526 m 422.42498779 158.62501526 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 174.97502136 m 422.42498779 174.97502136 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 191.32502747 m 422.42498779 191.32502747 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 207.67503357 m 423.17498779 207.67503357 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
endobj
6 0 obj
<</Length1 119 0 R/Length 30436>>stream
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