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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 269.45001221 0 0 -90.09999847 0 90.09999847 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 81.44200134 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>-4<0005>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 153.20599365 23.67700005 Tm 0 Tr [(mP)-1(l)1(um)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 223.41700745 23.67700005 Tm 2 Tr [<0006>-4<0007>-4<0008>-4<0005>-4<0009>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 333.85699463 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000A000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(mP)1(l)-1(um)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 129.87600708 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 182.37600708 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.62600708 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(m)1(Pl)-1(um)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.85900116 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.23300171 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.00500488 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.3789978 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.69999695 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.07400513 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.86999512 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010001100120013000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<0014001500050009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 105 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0016>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0017000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00180019001A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001B001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<001D001E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0020000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0021000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mP)1(l)-1(um)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.12599945 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0022002300240025000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mP)1(l)-1(um)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.12599945 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0026>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0027000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800120028000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 348.65100098 m 416.75 348.65100098 l 416.75 379.85101318 l -1.45000005 379.85101318 l h f* Q q 1 0 0 1 0 348.65100098 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 379.85101318 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 407.79000854 cm q /GS2 gs 1 g 0.375 0.75 m 167.92500305 0.75 l 167.92500305 125.55000305 l 0.375 125.55000305 l h f* Q q -0.625 -0.25 m 168.92500305 -0.25 l 168.92500305 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 66.3219986 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 66.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 168.67500305 0.75 m 422.42498779 0.75 l 422.42498779 125.55000305 l 168.67500305 125.55000305 l h f* Q q 1 0 0 1 168.30000305 0 cm -0.625 -0.25 m 255.125 -0.25 l 255.125 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(mPlum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.31299973 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.81299973 11.72200012 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.33100128 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.83100128 11.72200012 Tm [(preferred)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.08499908 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.58499908 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.86299896 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.36299896 11.72200012 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.30400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.80400085 11.72200012 Tm [(vivo)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.3690033 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.8690033 11.72200012 Tm [(imaging)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.29299927 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.79299927 11.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.07000732 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.57000732 11.72200012 Tm [(avo)1(id)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.14199829 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.64199829 11.72200012 Tm [(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(he)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.64799976 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.14799976 27.3220005 Tm [(natura)1(l)] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.37400055 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.87400055 27.3220005 Tm [(gr)1(e)-1(en)] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.8259964 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.3259964 27.3220005 Tm [(auto)1(fluoresc)-1(enc)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.19799805 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.69799805 27.3220005 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.38800049 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.88800049 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.82899475 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.32899475 27.3220005 Tm [(plant)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.51199341 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.01199341 27.3220005 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.75699997 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.25699997 42.92200089 Tm [(animals.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.30799866 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.80799866 42.92200089 Tm [(Livin)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.2440033 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.7440033 42.92200089 Tm [(Color)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.20500183 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.70500183 42.92200089 Tm [(mPlum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.01800537 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.51800537 42.92200089 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.07899475 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.57899475 42.92200089 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.55400085 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.05400085 42.92200089 Tm [(Fruit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.56599426 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.06599426 42.92200089 Tm [(Flu)-1(o)1(re)-1(s)1(c)-1(ent)] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.73699951 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(Pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.06500053 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.56499863 58.52199936 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.66199875 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.16200256 58.52199936 Tm [(wa)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.40899658 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.90899658 58.52199936 Tm [(developed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.33099365 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.83099365 58.52199936 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.77200317 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.27200317 58.52199936 Tm [(Dr.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.72999573 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.22999573 58.52199936 Tm [(Rog)1(e)-1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.1269989 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.6269989 58.52199936 Tm [(Tsie)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218 58.52199936 Tm [(?] TJ ET EMC /P <> BDC BT 1 0 0 -1 227 58.52199936 Tm [(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.16600037 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.66600037 58.52199936 Tm [(la)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(b)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.74800014 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.24800014 74.12200165 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.76000023 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.26000023 74.12200165 Tm [(directed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.68399811 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.18399811 74.12200165 Tm [(mutag)1(e)-1(nesis)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.73300171 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.23300171 74.12200165 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.07499695 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.57499695 74.12200165 Tm [(mRFP1,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.61599731 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.11599731 74.12200165 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.09100342 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.59100342 74.12200165 Tm [(monomeric)] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.897995 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.397995 74.12200165 Tm [(m)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(utant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.77199936 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.27199936 89.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.11399841 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.61399841 89.72200012 Tm [(DsR)1(e)-1(d)1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.54100037 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.04100037 89.72200012 Tm [(It)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.04000092 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.54000092 89.72200012 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.22200012 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.72200012 89.72200012 Tm [(demonst)1(rated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.43200684 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.93200684 89.72200012 Tm [(st)1(able)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.67500305 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.17500305 89.72200012 Tm [(expression)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 2.16700006 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 6.66699982 105.3219986 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.94400024 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.44400024 105.3219986 Tm [(perfo)1(rm)] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.44599915 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.94599915 105.3219986 Tm [(suc)-1(cessfully)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.34200287 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.84200287 105.3219986 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.78300476 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.28300476 105.3219986 Tm [(nume)-1(ro)1(u)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.78399658 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.28399658 105.3219986 Tm [(fusion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.77900696 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.27900696 105.3219986 Tm [(ap)1(plic)-1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(tio)1(n)-1(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.34799957 120.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 125.55000305 cm q /GS2 gs 1 g 0.375 0.75 m 167.92500305 0.75 l 167.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 168.92500305 -0.25 l 168.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 168.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 168.67500305 16.35000038 l h f* Q q 1 0 0 1 168.30000305 0 cm -0.625 -0.25 m 255.125 -0.25 l 255.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB)] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.80500031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 141.8999939 cm q /GS2 gs 1 g 0.375 0.75 m 167.92500305 0.75 l 167.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 168.92500305 -0.25 l 168.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 168.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 168.67500305 16.35000038 l h f* Q q 1 0 0 1 168.30000305 0 cm -0.625 -0.25 m 255.125 -0.25 l 255.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(mPlum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.31299973 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 158.25 cm q /GS2 gs 1 g 0.375 0.75 m 167.92500305 0.75 l 167.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 168.92500305 -0.25 l 168.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunogen:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 168.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 168.67500305 16.35000038 l h f* Q q 1 0 0 1 168.30000305 0 cm -0.625 -0.25 m 255.125 -0.25 l 255.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purified)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.26200104 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.76200104 11.72200012 Tm [(mPlum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.07499695 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.57499695 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.88200378 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.38200378 11.72200012 Tm [(expressed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.53599548 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.03599548 11.72200012 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.977005 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.477005 11.72200012 Tm [(HEK29)-1(3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.93299866 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.43299866 11.72200012 Tm [(ce)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.84300232 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 174.6000061 cm q /GS2 gs 1 g 0.375 0.75 m 167.92500305 0.75 l 167.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 168.92500305 -0.25 l 168.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.8380003 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.33799934 11.72200012 Tm [(Predic)1(ted)] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.54499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.04499817 11.72200012 Tm [(band)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.05000305 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.55000305 11.72200012 Tm [(siz)1(e:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 115.08799744 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 168.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 168.67500305 16.35000038 l h f* Q q 1 0 0 1 168.30000305 0 cm -0.625 -0.25 m 255.125 -0.25 l 255.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(26)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.55599976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.05599976 11.72200012 Tm [(kDa)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.7859993 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 190.94999695 cm q /GS2 gs 1 g 0.375 0.75 m 167.92500305 0.75 l 167.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 168.92500305 -0.25 l 168.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.8380003 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.33799934 11.72200012 Tm [(Positive)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.09600067 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.59600067 11.72200012 Tm [(control:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 95.68199921 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 168.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 168.67500305 16.35000038 l h f* Q q 1 0 0 1 168.30000305 0 cm -0.625 -0.25 m 255.125 -0.25 l 255.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(HEK29)-1(3T)] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.61500168 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.11500168 11.72200012 Tm [(ce)-1(lls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.69100189 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.19100189 11.72200012 Tm [(were)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.94599915 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.44599915 11.72200012 Tm [(tr)1(ansfec)-1(t)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.87800598 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.37800598 11.72200012 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.77400208 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.27400208 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.2749939 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.7749939 11.72200012 Tm [(pCMV6-ENTR)] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 207.30003357 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 168.30000305 0.75 m 168.30000305 125.55000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 168.30000305 126.30000305 m 168.30000305 141.90000916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 168.30000305 142.65000916 m 168.30000305 158.25001526 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 168.30000305 159.00001526 m 168.30000305 174.60002136 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 168.30000305 175.35002136 m 168.30000305 190.95002747 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 168.30000305 191.70002747 m 168.30000305 207.30003357 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 207.30003357 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 125.92500305 m 422.42498779 125.92500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 142.27500916 m 422.42498779 142.27500916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 158.62501526 m 422.42498779 158.62501526 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 174.97502136 m 422.42498779 174.97502136 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 191.32502747 m 422.42498779 191.32502747 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 207.67503357 m 423.17498779 207.67503357 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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