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g [<000A000B000C000D000E>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(mK)1(ate)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 127.36399841 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 179.86399841 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 185.11399841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(m)1(Kate)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 111.34700012 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 113.72100067 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 142.49299622 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 144.86700439 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 195.18800354 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 197.56199646 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 235.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010001100120013000E>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<0014001500050009>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 105 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 26 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0016>] TJ ET EMC /P <</MCID 27 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 28 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0017000E>] TJ ET EMC /P <</MCID 29 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 30 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00180019001A>] TJ ET EMC /P <</MCID 31 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 32 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001B001C>] TJ ET EMC /P <</MCID 33 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 34 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<001D001E>] TJ ET EMC /P <</MCID 35 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001F>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0020000E>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0021000E>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mK)1(ate)] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 90.61399841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0022002300240025000E>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mK)1(ate)] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 90.61399841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 55 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0026>] TJ ET EMC /P <</MCID 56 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 57 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0027000E>] TJ ET EMC /P <</MCID 58 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800120028000E>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 348.65100098 m 416.75 348.65100098 l 416.75 379.85101318 l -1.45000005 379.85101318 l h f* Q q 1 0 0 1 0 348.65100098 cm /P <</MCID 68 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 69 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 70 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 379.85101318 cm /P <</MCID 71 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 407.79000854 cm q /GS2 gs 1 g 0.375 0.75 m 185.17500305 0.75 l 185.17500305 187.94999695 l 0.375 187.94999695 l h f* Q q -0.625 -0.25 m 186.17500305 -0.25 l 186.17500305 188.94999695 l -0.625 188.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 72 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 97.52200317 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 73 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 97.52200317 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 185.92500305 0.75 m 422.42498779 0.75 l 422.42498779 187.94999695 l 185.92500305 187.94999695 l h f* Q q 1 0 0 1 185.55000305 0 cm -0.625 -0.25 m 237.875 -0.25 l 237.875 188.94999695 l -0.625 188.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 74 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(fa)1(r-red)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 50.0320015 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 54.5320015 11.72200012 Tm [(fluoresce)-1(nt)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 102.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 107.04199982 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 138.34899902 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 142.84899902 11.72200012 Tm [(mKat)1(e)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 170.42900085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 174.92900085 11.72200012 Tm [(\(lambd)1(a\(ex\),)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 228.06300354 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(58)-1(8)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 15.83300018 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 20.33300018 27.3220005 Tm [(nm;)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 36.47900009 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 40.97900009 27.3220005 Tm [(lambd)1(a\(em\),)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 94.97899628 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 99.47899628 27.3220005 Tm [(63)-1(5)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 115.31199646 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 119.81199646 27.3220005 Tm [(nm;)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 135.95799255 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 140.45799255 27.3220005 Tm [(chromop)1(hor)1(e)-1(-)1(formi)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ng)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 11.30300045 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 15.80300045 42.92200089 Tm [(tr)1(i)-1(a)1(d)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 35.71900177 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 40.21900177 42.92200089 Tm [(Met\(63)-1(\)-)1(T)-1(yr\(64)-1(\)-)1(Gly\(6)-1(5\)\),)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 147.34399414 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 151.84399414 42.92200089 Tm [(orig)1(in)-1(a)1(ting)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 199.11999512 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 203.61999512 42.92200089 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 224.33099365 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(wild)1(-type)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 40.51800156 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 45.01800156 58.52199936 Tm [(red)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 59.31800079 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 63.81800079 58.52199936 Tm [(fluoresce)-1(nt)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 111.82800293 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 116.32800293 58.52199936 Tm [(pro)1(geni)-1(t)1(or)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 162.55000305 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 167.05000305 58.52199936 Tm [(eqFP5)-1(78)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 204.03399658 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 208.53399658 58.52199936 Tm [(\(sea)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 225.78700256 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(anemone)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 40.43399811 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 44.93399811 74.12200165 Tm [(Enta)1(c)-1(maea)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 91.75800323 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 96.25800323 74.12200165 Tm [(quad)1(ric)-1(o)1(l)-1(o)1(r\),)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 151.08399963 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 155.58399963 74.12200165 Tm [(is)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 162.14500427 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 166.64500427 74.12200165 Tm [(monomeric)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 215.95199585 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 220.45199585 74.12200165 Tm [(a)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(nd)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 11.30300045 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 15.80300045 89.72200012 Tm [(chara)1(c)-1(terized)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 73.33599854 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 77.83599854 89.72200012 Tm [(by)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 88.34799957 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 92.84799957 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 106.84899902 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 111.34899902 89.72200012 Tm [(pro)1(noun)-1(ced)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 163.99099731 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 168.49099731 89.72200012 Tm [(pH)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 181.19999695 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 185.69999695 89.72200012 Tm [(dependen)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ce)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 9.61999989 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 14.11999989 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 22.96199989 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 27.46199989 105.3219986 Tm [(fluoresce)-1(nce)-1(,)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 83.90499878 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 88.40499878 105.3219986 Tm [(relatively)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 127.05500031 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 131.55499268 105.3219986 Tm [(hig)1(h)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 150.78999329 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 155.28999329 105.3219986 Tm [(brig)1(htness,)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 202.67199707 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 207.17199707 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 223.44900513 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(hig)1(h)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 19.23500061 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 23.73500061 120.92199707 Tm [(ph)1(oto)1(stab)1(il)-1(it)1(y.)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 85.53099823 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 90.03099823 120.92199707 Tm [(The)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 105.83799744 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 110.33799744 120.92199707 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 141.64500427 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 146.14500427 120.92199707 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 160.82699585 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 165.32699585 120.92199707 Tm [(been)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 186.83399963 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 191.33399963 120.92199707 Tm [(cry)-1(s)1(talliz)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(ed)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 10.86299992 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 15.36299992 136.52200317 Tm [(at)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 23.69099998 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 28.19099998 136.52200317 Tm [(a)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 33.16600037 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 37.66600037 136.52200317 Tm [(pH)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 50.375 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 54.875 136.52200317 Tm [(rang)1(i)-1(ng)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 88.28700256 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 92.78700256 136.52200317 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 113.4980011 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 117.9980011 136.52200317 Tm [(2)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 123.27600098 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 127.77600098 136.52200317 Tm [(to)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 136.85099792 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 141.35099792 136.52200317 Tm [(9)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 146.6289978 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 151.1289978 136.52200317 Tm [(in)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 159.07000732 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 163.57000732 136.52200317 Tm [(th)1(re)-1(e)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 186.11399841 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 190.61399841 136.52200317 Tm [(spa)1(c)-1(e)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 215.12199402 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 219.62199402 136.52200317 Tm [(gr)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(oups,)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 23.34799957 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 27.84799957 152.12199402 Tm [(and)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 44.125 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 48.625 152.12199402 Tm [(fo)1(u)-1(r)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 66.4489975 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 70.9489975 152.12199402 Tm [(st)1(ruc)-1(tures)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 113.5719986 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 118.0719986 152.12199402 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 138.41900635 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 142.91900635 152.12199402 Tm [(been)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 164.42599487 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 168.92599487 152.12199402 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 218.92300415 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 223.42300415 152.12199402 Tm [(b)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(y)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 4.76399994 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 9.26399994 167.72200012 Tm [(x-)1(ray)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 30.8939991 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 35.39400101 167.72200012 Tm [(cry)-1(s)1(tallog)1(raph)1(y)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 101.33399963 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 105.83399963 167.72200012 Tm [(at)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 114.16200256 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 118.66200256 167.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 132.66299438 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 137.16299438 167.72200012 Tm [(resolution)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 180.55000305 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 185.05000305 167.72200012 Tm [(of)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 193.89199829 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 198.39199829 167.72200012 Tm [(1.7)-1(5-2.)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 0 183.32200623 Tm [(6)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 5.27799988 183.32200623 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 9.77799988 183.32200623 Tm [(A.)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 18.27700043 183.32200623 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 187.94999695 cm q /GS2 gs 1 g 0.375 0.75 m 185.17500305 0.75 l 185.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 186.17500305 -0.25 l 186.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 229 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 230 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 185.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 185.92500305 16.35000038 l h f* Q q 1 0 0 1 185.55000305 0 cm -0.625 -0.25 m 237.875 -0.25 l 237.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 231 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 14.80500031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 185.55000305 0.75 m 185.55000305 187.94999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 185.55000305 188.69999695 m 185.55000305 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 188.32499695 m 422.42498779 188.32499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 204.67500305 m 423.17498779 204.67500305 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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