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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 82.20500183 23.67700005 Tm 0 g [(NFKB)1(ID)] TJ ET EMC /P <</Lang (zh-CN) /MCID 1 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 156.39100647 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 333.09500122 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 3 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 4 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(NFKB)1(ID)] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 86.99900055 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 170.99899292 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(NFKB)1(ID)] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 94.87400055 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 97.2480011 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 130.44999695 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 132.82400513 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 192.80400085 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 195.17799377 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 229.6519928 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 17 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 18 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 19 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0012000F>] TJ ET EMC /P <</MCID 20 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001300140005>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0015000A>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 25 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0016001700180019000F>] TJ ET EMC /P <</MCID 26 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 27 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 28 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 30 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B>] TJ ET EMC /P <</MCID 31 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 21 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 208.89500427 cm /P <</MCID 32 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 236.83399963 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 33 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 27.9109993 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 30.28499985 12.55799961 Tm [(protein)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 61.66699982 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 64.04100037 12.55799961 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 125.62599945 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 128 12.55799961 Tm [(to)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 137.05400085 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 139.42799377 12.55799961 Tm [(a)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 144.45799255 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 146.83200073 12.55799961 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 174.1230011 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 176.49699402 12.55799961 Tm [(derive)1(d)] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 208.79200745 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 211.16600037 12.55799961 Tm [(from)] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 231.95599365 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 234.33000183 12.55799961 Tm [(1-221)] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 258.83200073 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 261.20599365 12.55799961 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 288.08700562 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 290.46099854 12.55799961 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 311.9630127 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 314.33700562 12.55799961 Tm [(of)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 323.07800293 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 325.45199585 12.55799961 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 355.41900635 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 357.79299927 12.55799961 Tm [(NFKB)1(ID)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 389.66699219 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 265.77301025 cm /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 293.71200562 cm /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 321.65100098 cm /P <</MCID 64 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 349.58999634 cm q /GS2 gs 1 g 0.375 0.75 m 113.22499847 0.75 l 113.22499847 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 114.22499847 -0.25 l 114.22499847 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 65 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 16.18099976 19.52199936 Tm [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 20.68099976 19.52199936 Tm [(name:)] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.97499847 0.75 m 426.17501831 0.75 l 426.17501831 31.95000076 l 113.97499847 31.95000076 l h f* Q q 1 0 0 1 113.59999847 0 cm -0.625 -0.25 m 313.57501221 -0.25 l 313.57501221 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 69 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(nuc)-1(lear)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 31.51799965 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 36.01800156 11.72200012 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 61.13700104 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 65.63700104 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 74.47899628 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 78.97899628 11.72200012 Tm [(kappa)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 105.3239975 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 109.8239975 11.72200012 Tm [(light)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 129.26499939 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 133.76499939 11.72200012 Tm [(po)1(l)-1(yp)1(e)-1(pt)1(ide)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 185.60699463 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 190.10699463 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 211.6230011 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 216.1230011 11.72200012 Tm [(en)-1(h)1(anc)-1(er)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 255.89399719 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 260.39401245 11.72200012 Tm [(in)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 268.33499146 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 272.83499146 11.72200012 Tm [(B-c)-1(ells)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 300.95098877 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(inhibito)1(r,)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 38.69800186 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 43.19800186 27.3220005 Tm [(delta)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 64.78399658 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 31.95000076 cm q /GS2 gs 1 g 0.375 0.75 m 113.22499847 0.75 l 113.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.22499847 -0.25 l 114.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 93 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 94 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 113.97499847 16.35000038 l h f* Q q 1 0 0 1 113.59999847 0 cm -0.625 -0.25 m 313.57501221 -0.25 l 313.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 95 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(TA-)1(NF)-1(K)1(B)-1(H,)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 47.97100067 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 52.47100067 11.72200012 Tm [(Ikapp)1(aB)-1(NS)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 99.62000275 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 48.29999924 cm q /GS2 gs 1 g 0.375 0.75 m 113.22499847 0.75 l 113.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.22499847 -0.25 l 114.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 99 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 100 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 113.97499847 16.35000038 l h f* Q q 1 0 0 1 113.59999847 0 cm -0.625 -0.25 m 313.57501221 -0.25 l 313.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 101 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q8NI3)-1(8)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 33.13000107 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 64.65000153 cm q /GS2 gs 1 g 0.375 0.75 m 113.22499847 0.75 l 113.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.22499847 -0.25 l 114.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 103 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 106 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 113.97499847 16.35000038 l h f* Q q 1 0 0 1 113.59999847 0 cm -0.625 -0.25 m 313.57501221 -0.25 l 313.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 107 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(06)-1(27)-1(3)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81 cm q /GS2 gs 1 g 0.375 0.75 m 113.22499847 0.75 l 113.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.22499847 -0.25 l 114.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 109 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 110 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 113.97499847 16.35000038 l h f* Q q 1 0 0 1 113.59999847 0 cm -0.625 -0.25 m 313.57501221 -0.25 l 313.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 111 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 97.34999847 cm q /GS2 gs 1 g 0.375 0.75 m 113.22499847 0.75 l 113.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.22499847 -0.25 l 114.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 127 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 130 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 113.97499847 16.35000038 l h f* Q q 1 0 0 1 113.59999847 0 cm -0.625 -0.25 m 313.57501221 -0.25 l 313.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 131 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 113.69999695 cm q /GS2 gs 1 g 0.375 0.75 m 113.22499847 0.75 l 113.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.22499847 -0.25 l 114.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 135 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 136 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 113.97499847 16.35000038 l h f* Q q 1 0 0 1 113.59999847 0 cm -0.625 -0.25 m 313.57501221 -0.25 l 313.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 137 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 130.05000305 cm q /GS2 gs 1 g 0.375 0.75 m 113.22499847 0.75 l 113.22499847 141.1499939 l 0.375 141.1499939 l h f* Q q -0.625 -0.25 m 114.22499847 -0.25 l 114.22499847 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 149 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 74.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 150 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.97499847 0.75 m 426.17501831 0.75 l 426.17501831 141.1499939 l 113.97499847 141.1499939 l h f* Q q 1 0 0 1 113.59999847 0 cm -0.625 -0.25 m 313.57501221 -0.25 l 313.57501221 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 151 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(May)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 18.53199959 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 23.03199959 11.72200012 Tm [(regulat)1(e)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 58.70700073 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 63.20700073 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 77.20800018 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 81.70800018 11.72200012 Tm [(expression)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 127.66200256 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 132.16200256 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 141.0039978 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 145.5039978 11.72200012 Tm [(IL-2,)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 164.10600281 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 168.60600281 11.72200012 Tm [(IL-6,)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 187.20799255 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 191.70799255 11.72200012 Tm [(and)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 207.98500061 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 212.48500061 11.72200012 Tm [(ot)1(her)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 235.64399719 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 240.14399719 11.72200012 Tm [(cy)-1(t)1(oki)-1(nes)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 280.60900879 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 285.10900879 11.72200012 Tm [(th)1(ro)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ugh)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 16.84399986 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 21.34399986 27.3220005 Tm [(regulat)1(i)-1(o)1(n)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 65.57499695 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 70.07499695 27.3220005 Tm [(on)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 81.34300232 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 85.84300232 27.3220005 Tm [(NF-kapp)1(a-B)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 137.72000122 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 142.22000122 27.3220005 Tm [(activit)1(y)-1(.)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 174.85800171 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 179.35800171 27.3220005 Tm [(Fun)-1(ctions)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 220.92599487 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 225.42599487 27.3220005 Tm [(in)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 233.36700439 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 237.86700439 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 251.86799622 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 256.36801147 27.3220005 Tm [(regulat)1(i)-1(o)1(n)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 300.59899902 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 8.84200001 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 13.34200001 42.92200089 Tm [(inflammat)1(ory)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 70.88800049 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 75.38800049 42.92200089 Tm [(responses.)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 120.71800232 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 125.21800232 42.92200089 Tm [(May)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 143.75 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 148.25 42.92200089 Tm [(also)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 165.50700378 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 170.00700378 42.92200089 Tm [(regulat)1(e)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 205.68200684 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 210.18200684 42.92200089 Tm [(TCR-induce)-1(d)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 265.75100708 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 270.25100708 42.92200089 Tm [(ne)-1(g)1(ativ)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(e)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 5.10599995 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 9.60599995 58.52199936 Tm [(sele)-1(ction)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 47.9090004 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 52.4090004 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 61.25099945 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 65.75099945 58.52199936 Tm [(th)1(y)-1(mo)1(c)-1(ytes.I)] TJ ET EMC /P <</Lang (zh-CN) /MCID 212 >> BDC BT /FAAADA 9 Tf 1 0 0 -1 120.27799988 58.52199936 Tm [<0036>] TJ ET EMC /P <</MCID 213 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 125.4240036 58.52199936 Tm [(BNS)-1(,)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 145.74899292 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 150.24899292 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 164.25 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 168.75 58.52199936 Tm [(nuc)-1(lear)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 200.26800537 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 204.76800537 58.52199936 Tm [(I)] TJ ET EMC /P <</Lang (zh-CN) /MCID 220 >> BDC BT /FAAADA 9 Tf 1 0 0 -1 207.41400146 58.52199936 Tm [<0036>] TJ ET EMC /P <</MCID 221 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 212.55999756 58.52199936 Tm [(B-lik)-1(e)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 236.89700317 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 241.39700317 58.52199936 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 272.70401001 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 277.20401001 58.52199936 Tm [(en)-1(cod)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ed)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 10.86299992 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 15.36299992 74.12200165 Tm [(by)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 25.875 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 30.375 74.12200165 Tm [(Nfkbid,)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 61.77799988 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 66.27799988 74.12200165 Tm [(is)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 72.83899689 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 77.33899689 74.12200165 Tm [(required)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 113.87999725 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 118.37999725 74.12200165 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 130.65800476 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 135.15800476 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 149.15899658 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 153.65899658 74.12200165 Tm [(development)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 210.65600586 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 215.15600586 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 223.9980011 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 228.4980011 74.12200165 Tm [(marg)1(in)-1(a)1(l)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 266.41000366 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 270.91000366 74.12200165 Tm [(zo)1(n)-1(e)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 291.70901489 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 296.20901489 74.12200165 Tm [(a)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(nd)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 11.30300045 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 15.80300045 89.72200012 Tm [(perito)1(n)-1(eal)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 59.58599854 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 64.08599854 89.72200012 Tm [(B-1)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 78.90399933 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 83.40399933 89.72200012 Tm [(B)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 89.0510025 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 93.5510025 89.72200012 Tm [(ce)-1(lls)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 112.1269989 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 116.6269989 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 132.90400696 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 137.40400696 89.72200012 Tm [(ad)1(ditionally)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 187.83099365 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 192.33099365 89.72200012 Tm [(required)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 228.87199402 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 233.37199402 89.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 245.6499939 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 250.1499939 89.72200012 Tm [(extra)1(follic)-1(ula)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(r)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 3.43700004 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 7.9369998 105.3219986 Tm [(antib)1(ody)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 46.19599915 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 50.69599915 105.3219986 Tm [(responses)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 93.85900116 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 98.35900116 105.3219986 Tm [(to)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 107.43399811 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 111.93399811 105.3219986 Tm [(T-independe)-1(nt)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 175.95399475 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 180.45399475 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 196.73100281 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 201.23100281 105.3219986 Tm [(-d)1(e)-1(p)1(e)-1(ndent)] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 252.1499939 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 256.6499939 105.3219986 Tm [(immun)-1(o)1(ge)] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(ns.I)] TJ ET EMC /P <</Lang (zh-CN) /MCID 284 >> BDC BT /FAAADA 9 Tf 1 0 0 -1 14.52400017 120.92199707 Tm [<0036>] TJ ET EMC /P <</MCID 285 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 19.67000008 120.92199707 Tm [(BNS)] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 37.82799911 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 42.32799911 120.92199707 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 57.00999832 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 61.50999832 120.92199707 Tm [(been)] TJ ET EMC /P <</MCID 290 >> BDC BT 1 0 0 -1 83.01699829 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 291 >> BDC BT 1 0 0 -1 87.51699829 120.92199707 Tm [(identified)] TJ ET EMC /P <</MCID 292 >> BDC BT 1 0 0 -1 128.44799805 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 293 >> BDC BT 1 0 0 -1 132.94799805 120.92199707 Tm [(as)] TJ ET EMC /P <</MCID 294 >> BDC BT 1 0 0 -1 142.08900452 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 295 >> BDC BT 1 0 0 -1 146.58900452 120.92199707 Tm [(a)] TJ ET EMC /P <</MCID 296 >> BDC BT 1 0 0 -1 151.56399536 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 297 >> BDC BT 1 0 0 -1 156.06399536 120.92199707 Tm [(member)] TJ ET EMC /P <</MCID 298 >> BDC BT 1 0 0 -1 192.32800293 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 299 >> BDC BT 1 0 0 -1 196.82800293 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 300 >> BDC BT 1 0 0 -1 205.66999817 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 301 >> BDC BT 1 0 0 -1 210.16999817 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 302 >> BDC BT 1 0 0 -1 224.17100525 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 303 >> BDC BT 1 0 0 -1 228.67100525 120.92199707 Tm [(I)] TJ ET EMC /P <</Lang (zh-CN) /MCID 304 >> BDC BT /FAAADA 9 Tf 1 0 0 -1 231.31700134 120.92199707 Tm [<0036>] TJ ET EMC /P <</MCID 305 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 236.46299744 120.92199707 Tm [(B)] TJ ET EMC /P <</MCID 306 >> BDC BT 1 0 0 -1 242.11000061 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 307 >> BDC BT 1 0 0 -1 246.61000061 120.92199707 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 308 >> BDC BT 1 0 0 -1 272.69198608 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 309 >> BDC BT 1 0 0 -1 277.19198608 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 310 >> BDC BT 1 0 0 -1 286.03399658 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 311 >> BDC BT 1 0 0 -1 290.53399658 120.92199707 Tm [(NF)] TJ ET EMC /P <</MCID 312 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(-)] TJ ET EMC /P <</Lang (zh-CN) /MCID 313 >> BDC BT /FAAADA 9 Tf 1 0 0 -1 3.89400005 136.52200317 Tm [<0036>] TJ ET EMC /P <</MCID 314 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 9.03999996 136.52200317 Tm [(B)] TJ ET EMC /P <</MCID 315 >> BDC BT 1 0 0 -1 14.68700027 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 316 >> BDC BT 1 0 0 -1 19.18700027 136.52200317 Tm [(inhibito)1(rs,)] TJ ET EMC /P <</MCID 317 >> BDC BT 1 0 0 -1 62.05099869 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 318 >> BDC BT 1 0 0 -1 66.5510025 136.52200317 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 319 >> BDC BT 1 0 0 -1 91.64800262 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 320 >> BDC BT 1 0 0 -1 96.14800262 136.52200317 Tm [(undergoes)] TJ ET EMC /P <</MCID 321 >> BDC BT 1 0 0 -1 142.29100037 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 322 >> BDC BT 1 0 0 -1 146.79100037 136.52200317 Tm [(induc)-1(t)1(ion)] TJ ET EMC /P <</MCID 323 >> BDC BT 1 0 0 -1 187.56300354 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 324 >> BDC BT 1 0 0 -1 192.06300354 136.52200317 Tm [(upon)] TJ ET EMC /P <</MCID 325 >> BDC BT 1 0 0 -1 214.625 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 326 >> BDC BT 1 0 0 -1 219.125 136.52200317 Tm [(TCR)] TJ ET EMC /P <</MCID 327 >> BDC BT 1 0 0 -1 236.17999268 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 328 >> BDC BT 1 0 0 -1 240.67999268 136.52200317 Tm [(signaling.)] TJ ET EMC /P <</MCID 329 >> BDC BT 1 0 0 -1 281.77801514 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 330 >> BDC BT 1 0 0 -1 286.27801514 136.52200317 Tm [(I)] TJ ET EMC /P <</Lang (zh-CN) /MCID 331 >> BDC BT /FAAADA 9 Tf 1 0 0 -1 288.92401123 136.52200317 Tm [<0036>] TJ ET EMC /P <</MCID 332 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 294.07000732 136.52200317 Tm [(B)] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 271.20001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.59999847 0.75 m 113.59999847 31.95000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.59999847 32.70000076 m 113.59999847 48.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.59999847 49.05000305 m 113.59999847 64.65000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.59999847 65.40000153 m 113.59999847 81 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.59999847 81.75 m 113.59999847 97.34999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.59999847 98.09999847 m 113.59999847 113.69999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.59999847 114.44999695 m 113.59999847 130.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.59999847 130.80000305 m 113.59999847 271.20001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.55001831 0.75 m 426.55001831 271.20001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92501831 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 32.32500076 m 426.17501831 32.32500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 48.67500305 m 426.17501831 48.67500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.02500153 m 426.17501831 65.02500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 81.375 m 426.17501831 81.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 97.72499847 m 426.17501831 97.72499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.07499695 m 426.17501831 114.07499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 130.42500305 m 426.17501831 130.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 271.57501221 m 426.92501831 271.57501221 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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