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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 87.74299622 23.67700005 Tm 0 g [(KRT18)] TJ ET EMC /P <> BDC BT /FAAABE 22 Tf 1 0 0 -1 150.85299683 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 327.55700684 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(KRT18)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 82.04199982 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 166.04200745 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(KRT18)] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.91699982 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.29100037 12.82499981 Tm [(Antigen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.49299622 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.86699677 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.84700012 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.22099304 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.69500732 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0012000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001300140005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0015000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0016001700180019000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 21 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 208.89500427 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 236.83399963 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.9109993 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.28499985 12.55799961 Tm [(protein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.66699982 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.04100037 12.55799961 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.62599945 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128 12.55799961 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.05400085 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.42799377 12.55799961 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.45799255 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.83200073 12.55799961 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.1230011 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.49699402 12.55799961 Tm [(derive)1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.79200745 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.16600037 12.55799961 Tm [(from)] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.95599365 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.33000183 12.55799961 Tm [(130-4)1(30)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.4750061 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.84899902 12.55799961 Tm [(amin)-1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 298.73001099 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 301.10400391 12.55799961 Tm [(acid)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 322.60598755 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 324.98001099 12.55799961 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 333.7210083 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 336.09500122 12.55799961 Tm [(hu)-1(man)] TJ ET EMC /P <> BDC BT 1 0 0 -1 366.06201172 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 368.43600464 12.55799961 Tm [(KRT18)] TJ ET EMC /P <> BDC BT 1 0 0 -1 395.35299683 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 265.77301025 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 293.71200562 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 321.65100098 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 349.58999634 cm q /GS2 gs 1 g 0.375 0.75 m 115.22499847 0.75 l 115.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 116.22499847 -0.25 l 116.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 115.97499847 16.35000038 l h f* Q q 1 0 0 1 115.59999847 0 cm -0.625 -0.25 m 311.57501221 -0.25 l 311.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ke)-1(ra)1(tin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.71100044 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.21099854 11.72200012 Tm [(18)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.93299866 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.43299866 11.72200012 Tm [(type)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.40399933 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.90399933 11.72200012 Tm [(I)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.55000305 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 115.22499847 0.75 l 115.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 116.22499847 -0.25 l 116.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 115.97499847 16.35000038 l h f* Q q 1 0 0 1 115.59999847 0 cm -0.625 -0.25 m 311.57501221 -0.25 l 311.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(K18)-1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.43499947 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.93499947 11.72200012 Tm [(CY)1(K1)-1(8)] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.65599823 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 115.22499847 0.75 l 115.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 116.22499847 -0.25 l 116.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 115.97499847 16.35000038 l h f* Q q 1 0 0 1 115.59999847 0 cm -0.625 -0.25 m 311.57501221 -0.25 l 311.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(P05)-1(78)-1(3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.89599991 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 115.22499847 0.75 l 115.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 116.22499847 -0.25 l 116.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 115.97499847 16.35000038 l h f* Q q 1 0 0 1 115.59999847 0 cm -0.625 -0.25 m 311.57501221 -0.25 l 311.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(00)-1(18)-1(0)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 115.22499847 0.75 l 115.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 116.22499847 -0.25 l 116.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 115.97499847 16.35000038 l h f* Q q 1 0 0 1 115.59999847 0 cm -0.625 -0.25 m 311.57501221 -0.25 l 311.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 115.22499847 0.75 l 115.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 116.22499847 -0.25 l 116.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 115.97499847 16.35000038 l h f* Q q 1 0 0 1 115.59999847 0 cm -0.625 -0.25 m 311.57501221 -0.25 l 311.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 115.22499847 0.75 l 115.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 116.22499847 -0.25 l 116.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 115.97499847 16.35000038 l h f* Q q 1 0 0 1 115.59999847 0 cm -0.625 -0.25 m 311.57501221 -0.25 l 311.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 115.22499847 0.75 l 115.22499847 109.94999695 l 0.375 109.94999695 l h f* Q q -0.625 -0.25 m 116.22499847 -0.25 l 116.22499847 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 58.52199936 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 58.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.97499847 0.75 m 426.17501831 0.75 l 426.17501831 109.94999695 l 115.97499847 109.94999695 l h f* Q q 1 0 0 1 115.59999847 0 cm -0.625 -0.25 m 311.57501221 -0.25 l 311.57501221 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(KRT18)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.3029995 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.8029995 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.72000122 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.22000122 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.22100067 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.72100067 11.72200012 Tm [(type)] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.69200134 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.19200134 11.72200012 Tm [(I)] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.83799744 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.33799744 11.72200012 Tm [(intermediate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.30000305 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.80000305 11.72200012 Tm [(filament)] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.1230011 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.6230011 11.72200012 Tm [(chain)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.59300232 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.09300232 11.72200012 Tm [(ke)-1(ra)1(tin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 277.8039856 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 282.3039856 11.72200012 Tm [(18)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 295.02600098 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(Kerat)1(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.52400017 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.02399826 27.3220005 Tm [(18)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.74599838 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.24599838 27.3220005 Tm [(to)1(gether)] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.6210022 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.1210022 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.51699829 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.01699829 27.3220005 Tm [(its)] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.93099976 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.43099976 27.3220005 Tm [(filament)] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.7539978 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.2539978 27.3220005 Tm [(pa)1(rtner)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.85499573 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.35499573 27.3220005 Tm [(ke)-1(ra)1(tin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.06599426 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.56599426 27.3220005 Tm [(8,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.00999451 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.50999451 27.3220005 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.02801514 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.52801514 27.3220005 Tm [(perha)1(p)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 4.16599989 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.66600037 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.66699982 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.16699982 42.92200089 Tm [(most)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.8409996 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.3409996 42.92200089 Tm [(commonly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.86799622 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.36799622 42.92200089 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.05799866 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.55799866 42.92200089 Tm [(members)] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.98800659 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.48800659 42.92200089 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.33000183 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.83000183 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.83099365 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.33099365 42.92200089 Tm [(intermediate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.29299927 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.79299927 42.92200089 Tm [(filamen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 3.35299993 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 7.85300016 58.52199936 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.36899948 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.86899948 58.52199936 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.11700058 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.61699677 58.52199936 Tm [(They)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.18800354 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.68800354 58.52199936 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.20600128 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.70600128 58.52199936 Tm [(expressed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.86000061 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.36000061 58.52199936 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.30099487 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.80099487 58.52199936 Tm [(single)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.16600037 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.66600037 58.52199936 Tm [(laye)-1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.34199524 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.84199524 58.52199936 Tm [(epith)1(e)-1(lial)] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.25201416 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 268.75201416 58.52199936 Tm [(tiss)1(u)-1(es)] TJ ET EMC /P <> BDC BT 1 0 0 -1 297.6499939 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.84200001 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.34200001 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.34300041 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.84300041 74.12200165 Tm [(bo)1(dy.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.5 74.12200165 Tm [(Mutat)1(ions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.34899902 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.84899902 74.12200165 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.79000092 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.29000092 74.12200165 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.7460022 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.2460022 74.12200165 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.76199341 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.26199341 74.12200165 Tm [(ha)1(ve)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.60899353 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.10899353 74.12200165 Tm [(been)] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.61599731 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.11599731 74.12200165 Tm [(link)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.21499634 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.71499634 74.12200165 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.79000854 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.29000854 74.12200165 Tm [(cry)-1(p)1(tog)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(nic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.45400047 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.95400047 89.72200012 Tm [(ci)-1(r)1(rhosis.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.89199829 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.39199829 89.72200012 Tm [(Two)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.3789978 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.8789978 89.72200012 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.8010025 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.3010025 89.72200012 Tm [(var)1(i)-1(a)1(n)-1(t)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.8710022 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.3710022 89.72200012 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.71299744 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.21299744 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.21400452 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.71400452 89.72200012 Tm [(same)] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.39399719 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.89399719 89.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 287.20098877 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 291.70098877 89.72200012 Tm [(ha)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ve)] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.83100033 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.33100033 105.3219986 Tm [(been)] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.83800125 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.33800125 105.3219986 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.02799988 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.52799988 105.3219986 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.80599976 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.30599976 105.3219986 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.76200104 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.26200104 105.3219986 Tm [(gene)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.94400024 105.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.59999847 0.75 m 115.59999847 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.59999847 17.10000038 m 115.59999847 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.59999847 33.45000076 m 115.59999847 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.59999847 49.80000305 m 115.59999847 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.59999847 66.15000153 m 115.59999847 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.59999847 82.5 m 115.59999847 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.59999847 98.84999847 m 115.59999847 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.59999847 115.19999695 m 115.59999847 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.55001831 0.75 m 426.55001831 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92501831 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17501831 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17501831 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17501831 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17501831 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17501831 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17501831 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 426.17501831 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 224.7749939 m 426.92501831 224.7749939 l S Q Q q 1 0 0 1 0 574.73999023 cm Q Q 1 0 0 -1 0 841.90002441 cm
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