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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 89.41799927 23.67700005 Tm 0 g [(ITGB)1(6)] TJ ET EMC /P <</Lang (zh-CN) /MCID 1 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 149.17700195 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 325.88101196 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 3 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 4 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(ITGB6)] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 80.54399872 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 164.54400635 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ITGB6)] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 88.41899872 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 90.79299927 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 123.99500275 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 126.3690033 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 186.34899902 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 188.7230072 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 223.19700623 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 17 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 18 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 19 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 20 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(AI1)1(H)] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 83.58499908 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 25 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <</MCID 26 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 27 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <</MCID 28 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 29 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <</MCID 30 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 31 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <</MCID 32 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 33 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 34 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 21 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 242.43400574 cm /P <</MCID 38 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 270.37298584 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 27.9109993 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 30.28499985 12.55799961 Tm [(protein)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 61.66699982 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 64.04100037 12.55799961 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 125.62599945 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 128 12.55799961 Tm [(to)] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 137.05400085 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 139.42799377 12.55799961 Tm [(a)] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 144.45799255 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 146.83200073 12.55799961 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 174.1230011 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 176.49699402 12.55799961 Tm [(derive)1(d)] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 208.79200745 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 211.16600037 12.55799961 Tm [(from)] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 231.95599365 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 234.33000183 12.55799961 Tm [(139-4)1(34)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 269.4750061 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 271.84899902 12.55799961 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 298.73001099 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 301.10400391 12.55799961 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 322.60598755 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 324.98001099 12.55799961 Tm [(of)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 333.7210083 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 336.09500122 12.55799961 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 366.06201172 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 368.43600464 12.55799961 Tm [(ITGB6)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 393.85501099 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 299.31201172 cm /P <</MCID 67 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 327.25100708 cm /P <</Lang (zh-CN) /MCID 68 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F>] TJ ET EMC /P <</MCID 69 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 355.19000244 cm /P <</MCID 70 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 383.1289978 cm q /GS2 gs 1 g 0.375 0.75 m 117.22499847 0.75 l 117.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 118.22499847 -0.25 l 118.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 71 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 74 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 117.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 117.97499847 16.35000038 l h f* Q q 1 0 0 1 117.59999847 0 cm -0.625 -0.25 m 309.57501221 -0.25 l 309.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 75 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(integrin,)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 35.70100021 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 40.20100021 11.72200012 Tm [(beta)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 59.38299942 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 63.88299942 11.72200012 Tm [(6)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 69.16100311 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 117.22499847 0.75 l 117.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 118.22499847 -0.25 l 118.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 81 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 82 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 117.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 117.97499847 16.35000038 l h f* Q q 1 0 0 1 117.59999847 0 cm -0.625 -0.25 m 309.57501221 -0.25 l 309.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 83 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(AI1H)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 21.21699905 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 117.22499847 0.75 l 117.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 118.22499847 -0.25 l 118.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 85 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 86 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 117.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 117.97499847 16.35000038 l h f* Q q 1 0 0 1 117.59999847 0 cm -0.625 -0.25 m 309.57501221 -0.25 l 309.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 87 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(P18)-1(56)-1(4)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 31.89599991 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 117.22499847 0.75 l 117.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 118.22499847 -0.25 l 118.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 89 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 92 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 117.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 117.97499847 16.35000038 l h f* Q q 1 0 0 1 117.59999847 0 cm -0.625 -0.25 m 309.57501221 -0.25 l 309.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 93 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC1)-1(21)-1(17)-1(8)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 117.22499847 0.75 l 117.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 118.22499847 -0.25 l 118.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 95 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 96 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 117.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 117.97499847 16.35000038 l h f* Q q 1 0 0 1 117.59999847 0 cm -0.625 -0.25 m 309.57501221 -0.25 l 309.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 97 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 117.22499847 0.75 l 117.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 118.22499847 -0.25 l 118.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 113 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 116 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 117.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 117.97499847 16.35000038 l h f* Q q 1 0 0 1 117.59999847 0 cm -0.625 -0.25 m 309.57501221 -0.25 l 309.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 117 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 117.22499847 0.75 l 117.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 118.22499847 -0.25 l 118.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 121 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 122 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 117.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 117.97499847 16.35000038 l h f* Q q 1 0 0 1 117.59999847 0 cm -0.625 -0.25 m 309.57501221 -0.25 l 309.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 123 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 117.22499847 0.75 l 117.22499847 109.94999695 l 0.375 109.94999695 l h f* Q q -0.625 -0.25 m 118.22499847 -0.25 l 118.22499847 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 135 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 58.52199936 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 136 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 58.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 117.97499847 0.75 m 426.17501831 0.75 l 426.17501831 109.94999695 l 117.97499847 109.94999695 l h f* Q q 1 0 0 1 117.59999847 0 cm -0.625 -0.25 m 309.57501221 -0.25 l 309.57501221 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 137 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 128.977005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 133.477005 11.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 150.69900513 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 155.19900513 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 161.75999451 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 166.25999451 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 171.23500061 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 175.73500061 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 211.99899292 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 216.49899292 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 225.34100342 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 229.84100342 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 243.84199524 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 248.34199524 11.72200012 Tm [(integrin)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 281.87701416 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 286.37701416 11.72200012 Tm [(su)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(perfa)1(mil)-1(y.)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 42.53900146 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 47.03900146 27.3220005 Tm [(Membe)-1(r)1(s)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 87.82900238 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 92.32900238 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 101.17099762 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 105.67099762 27.3220005 Tm [(th)1(is)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 121.1269989 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 125.6269989 27.3220005 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 151.70899963 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 156.20899963 27.3220005 Tm [(are)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 169.727005 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 174.227005 27.3220005 Tm [(ad)1(hesion)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 213.43499756 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 217.93499756 27.3220005 Tm [(rec)-1(ept)1(ors)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 258.52301025 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 263.02301025 27.3220005 Tm [(th)1(at)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 280.24499512 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 284.74499512 27.3220005 Tm [(fun)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ction)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 21.52899933 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 26.02899933 42.92200089 Tm [(in)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 33.97000122 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 38.47000122 42.92200089 Tm [(signaling)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 77.40100098 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 81.90100098 42.92200089 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 102.61199951 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 107.11199951 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 121.11299896 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 125.61299896 42.92200089 Tm [(extra)1(c)-1(ellu)-1(la)1(r)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 177.80700684 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 182.30700684 42.92200089 Tm [(mat)1(rix)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 209.46099854 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 213.96099854 42.92200089 Tm [(to)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 223.03599548 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 227.53599548 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 241.53700256 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 246.03700256 42.92200089 Tm [(ce)-1(ll.)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 262.61300659 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 267.11300659 42.92200089 Tm [(Integrin)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(s)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 4.16599989 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 8.66600037 58.52199936 Tm [(are)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 22.18400002 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 26.68400002 58.52199936 Tm [(heterod)1(ime)-1(ric)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 86.98600006 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 91.48600006 58.52199936 Tm [(integra)1(l)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 124.4489975 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 128.94900513 58.52199936 Tm [(membrane)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 175.73300171 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 180.23300171 58.52199936 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 215.70599365 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 220.20599365 58.52199936 Tm [(composed)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 265.37298584 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 269.87298584 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 278.71499634 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 283.21499634 58.52199936 Tm [(an)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 293.73599243 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(alph)1(a)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 23.63400078 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 28.13400078 74.12200165 Tm [(chain)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 51.10400009 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 55.60400009 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 71.8809967 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 76.3809967 74.12200165 Tm [(a)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 81.35600281 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 85.85600281 74.12200165 Tm [(beta)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 105.03800201 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 109.53800201 74.12200165 Tm [(chain.)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 134.67500305 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 139.17500305 74.12200165 Tm [(The)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 154.98199463 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 159.48199463 74.12200165 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 196.98899841 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 201.48899841 74.12200165 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 232.79600525 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 237.29600525 74.12200165 Tm [(fo)1(rms)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 262.17300415 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 266.67300415 74.12200165 Tm [(a)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 271.64801025 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 276.14801025 74.12200165 Tm [(dimer)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 301.27600098 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 18.39599991 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 22.89599991 89.72200012 Tm [(an)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 33.41699982 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 37.91699982 89.72200012 Tm [(alph)1(a)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 61.55099869 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 66.0510025 89.72200012 Tm [(v)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 70.77500153 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 75.27500153 89.72200012 Tm [(chain)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 98.24500275 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 102.74500275 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 119.02200317 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 123.52200317 89.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 138.97799683 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 143.47799683 89.72200012 Tm [(heterod)1(ime)-1(r)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 196.87199402 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 201.37199402 89.72200012 Tm [(can)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 216.40600586 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 220.90600586 89.72200012 Tm [(bind)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 240.352005 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 244.852005 89.72200012 Tm [(to)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 253.92700195 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 258.42700195 89.72200012 Tm [(ligand)1(s)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 289.41699219 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 293.91699219 89.72200012 Tm [(li)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ke)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 10.00599957 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 14.50599957 105.3219986 Tm [(fib)1(rone)-1(ctin)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 61.38700104 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 65.88700104 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 82.16400146 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 86.66400146 105.3219986 Tm [(tr)1(ansfor)1(m)-1(ing)] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 142.54899597 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 147.04899597 105.3219986 Tm [(gr)1(owt)1(h)] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 177.96499634 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 182.46499634 105.3219986 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 207.58399963 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 212.08399963 105.3219986 Tm [(beta)] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 231.26600647 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 235.76600647 105.3219986 Tm [(1.)] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 243.21000671 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 247.71000671 105.3219986 Tm [(Alt)1(e)-1(rna)1(te)] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 287.31399536 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 291.81399536 105.3219986 Tm [(s)] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 117.59999847 0.75 m 117.59999847 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 117.59999847 17.10000038 m 117.59999847 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 117.59999847 33.45000076 m 117.59999847 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 117.59999847 49.80000305 m 117.59999847 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 117.59999847 66.15000153 m 117.59999847 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 117.59999847 82.5 m 117.59999847 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 117.59999847 98.84999847 m 117.59999847 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 117.59999847 115.19999695 m 117.59999847 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.55001831 0.75 m 426.55001831 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92501831 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 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