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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [(CDC)-1(2)1(5A)] TJ ET EMC /P <</Lang (zh-CN) /MCID 1 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 37.00099945 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 2 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 121.00099945 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 33.53900146 cm /P <</Lang (zh-CN) /MCID 3 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 4 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(CDC)-1(2)1(5A)] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 89.50099945 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 173.50100708 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 67.07800293 cm /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CDC)-1(2)1(5A)] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 97.37599945 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 99.75 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 132.95199585 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 135.32600403 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 195.30599976 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 197.67999268 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 232.15400696 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 100.61699677 cm /P <</Lang (zh-CN) /MCID 17 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 18 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 19 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0012000F>] TJ ET EMC /P <</MCID 20 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001300140005>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0015000A>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 134.15600586 cm /P <</Lang (zh-CN) /MCID 25 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0016001700180019000F>] TJ ET EMC /P <</MCID 26 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 27 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 28 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 167.69500732 cm /P <</Lang (zh-CN) /MCID 30 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B>] TJ ET EMC /P <</MCID 31 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 21 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 195.63400269 cm /P <</MCID 32 >> BDC BT 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 223.57299805 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 33 >> BDC BT 1 0 0 -1 0 12.55799961 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 27.9109993 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 30.28499985 12.55799961 Tm [(protein)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 61.66699982 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 64.04100037 12.55799961 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 125.62599945 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 128 12.55799961 Tm [(to)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 137.05400085 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 139.42799377 12.55799961 Tm [(a)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 144.45799255 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 146.83200073 12.55799961 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 174.1230011 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 176.49699402 12.55799961 Tm [(derive)1(d)] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 208.79200745 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 211.16600037 12.55799961 Tm [(from)] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 231.95599365 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 234.33000183 12.55799961 Tm [(376-4)1(82)] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 269.4750061 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 271.84899902 12.55799961 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 298.73001099 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 301.10400391 12.55799961 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 322.60598755 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 324.98001099 12.55799961 Tm [(of)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 333.7210083 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 336.09500122 12.55799961 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 366.06201172 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 368.43600464 12.55799961 Tm [(CDC)-1(2)1(5A)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 402.81201172 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS1 gs 0 G 0.5 w 0 0.5 m 0 28.43899918 l S Q q /GS1 gs 0 G 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q /GS1 gs 0 G 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q /GS1 gs 0 G 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 252.51199341 cm /P <</MCID 61 >> BDC BT 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 280.45098877 cm /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 308.39001465 cm /P <</MCID 64 >> BDC BT 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 336.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 108.67500305 0.75 l 108.67500305 30.45000076 l 0.375 30.45000076 l h f* Q q -0.625 -0.25 m 109.67500305 -0.25 l 109.67500305 31.45000076 l -0.625 31.45000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 65 >> BDC BT /FAAABI 9 Tf 1 0 0 -1 0 18.77199936 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 16.18099976 18.77199936 Tm [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 20.68099976 18.77199936 Tm [(name:)] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 48.35800171 18.77199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.42500305 0.75 m 426.17498779 0.75 l 426.17498779 30.45000076 l 109.42500305 30.45000076 l h f* Q q 1 0 0 1 109.05000305 0 cm -0.625 -0.25 m 318.125 -0.25 l 318.125 31.45000076 l -0.625 31.45000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 69 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 0 18.77199936 Tm /GS2 gs 0.13333334 g [(ce)-1(ll)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 14.40999985 18.77199936 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 18.90999985 18.77199936 Tm [(division)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 52.00999832 18.77199936 Tm [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 56.50999832 18.77199936 Tm [(cy)-1(cle)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 77.80200195 18.77199936 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 82.30200195 18.77199936 Tm [(25)-1(A)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 99.19000244 18.77199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 30.45000076 cm q /GS2 gs 1 g 0.375 0.75 m 108.67500305 0.75 l 108.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 109.67500305 -0.25 l 109.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 77 >> BDC BT /FAAABI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 109.42500305 16.35000038 l h f* Q q 1 0 0 1 109.05000305 0 cm -0.625 -0.25 m 318.125 -0.25 l 318.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 79 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CDC25A2)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 41.06200027 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 46.79999924 cm q /GS2 gs 1 g 0.375 0.75 m 108.67500305 0.75 l 108.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 109.67500305 -0.25 l 109.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 81 >> BDC BT /FAAABI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 82 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 109.42500305 16.35000038 l h f* Q q 1 0 0 1 109.05000305 0 cm -0.625 -0.25 m 318.125 -0.25 l 318.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 83 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(P30)-1(30)-1(4)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 31.89599991 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 63.15000153 cm q /GS2 gs 1 g 0.375 0.75 m 108.67500305 0.75 l 108.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 109.67500305 -0.25 l 109.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 85 >> BDC BT /FAAABI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 88 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 109.42500305 16.35000038 l h f* Q q 1 0 0 1 109.05000305 0 cm -0.625 -0.25 m 318.125 -0.25 l 318.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 89 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(07)-1(40)-1(1)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 79.5 cm q /GS2 gs 1 g 0.375 0.75 m 108.67500305 0.75 l 108.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 109.67500305 -0.25 l 109.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 91 >> BDC BT /FAAABI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 92 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 109.42500305 16.35000038 l h f* Q q 1 0 0 1 109.05000305 0 cm -0.625 -0.25 m 318.125 -0.25 l 318.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 93 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 95.84999847 cm q /GS2 gs 1 g 0.375 0.75 m 108.67500305 0.75 l 108.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 109.67500305 -0.25 l 109.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 109 >> BDC BT /FAAABI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 112 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 109.42500305 16.35000038 l h f* Q q 1 0 0 1 109.05000305 0 cm -0.625 -0.25 m 318.125 -0.25 l 318.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 113 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 112.19999695 cm q /GS2 gs 1 g 0.375 0.75 m 108.67500305 0.75 l 108.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 109.67500305 -0.25 l 109.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 117 >> BDC BT /FAAABI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 118 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 109.42500305 16.35000038 l h f* Q q 1 0 0 1 109.05000305 0 cm -0.625 -0.25 m 318.125 -0.25 l 318.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 119 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 128.55000305 cm q /GS2 gs 1 g 0.375 0.75 m 108.67500305 0.75 l 108.67500305 141.1499939 l 0.375 141.1499939 l h f* Q q -0.625 -0.25 m 109.67500305 -0.25 l 109.67500305 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 131 >> BDC BT /FAAABI 9 Tf 1 0 0 -1 0 74.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 132 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 57.29199982 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.42500305 0.75 m 426.17498779 0.75 l 426.17498779 141.1499939 l 109.42500305 141.1499939 l h f* Q q 1 0 0 1 109.05000305 0 cm -0.625 -0.25 m 318.125 -0.25 l 318.125 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 133 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CDC25A)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 35.78499985 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 40.28499985 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 46.84600067 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 51.34600067 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 56.32099915 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 60.82099915 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 97.08499908 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 101.58499908 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 110.42700195 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 114.92700195 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 128.92799377 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 133.42799377 11.72200012 Tm [(CDC25)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 162.88000488 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 167.38000488 11.72200012 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 193.46200562 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 197.96200562 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 206.80400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 211.30400085 11.72200012 Tm [(ph)1(osph)1(ata)1(se)-1(s.)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 272.67800903 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 277.17800903 11.72200012 Tm [(CDC25)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(A)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 6.33300018 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 10.83300018 27.3220005 Tm [(is)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 17.3939991 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 21.8939991 27.3220005 Tm [(required)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 58.43500137 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 62.93500137 27.3220005 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 75.21299744 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 79.71299744 27.3220005 Tm [(pro)1(gression)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 130.91400146 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 135.41400146 27.3220005 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 156.125 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 160.625 27.3220005 Tm [(G1)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 172.59599304 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 177.09599304 27.3220005 Tm [(to)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 186.17100525 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 190.67100525 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 204.67199707 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 209.17199707 27.3220005 Tm [(S)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 214.36599731 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 218.86599731 27.3220005 Tm [(ph)1(ase)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 244.40299988 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 248.90299988 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 257.74499512 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 262.24499512 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 276.2460022 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 280.7460022 27.3220005 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 295.15600586 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 299.65600586 27.3220005 Tm [(cy)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(cl)-1(e.)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 14.18099976 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 18.68099976 42.92200089 Tm [(It)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 24.68000031 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 29.18000031 42.92200089 Tm [(activat)1(es)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 66.73999786 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 71.23999786 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 85.24099731 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 89.74099731 42.92200089 Tm [(cy)-1(clin)-1(-)1(depen)-1(d)1(e)-1(nt)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 164.78599548 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 169.28599548 42.92200089 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 196.37399292 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 200.87399292 42.92200089 Tm [(CDC2)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 225.04800415 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 229.54800415 42.92200089 Tm [(by)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 240.05999756 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 244.55999756 42.92200089 Tm [(removing)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 285.67999268 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 290.17999268 42.92200089 Tm [(tw)1(o)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 306.36099243 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ph)1(osph)1(ate)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 45.90100098 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 50.40100098 58.52199936 Tm [(gr)1(oups.)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 82.94300079 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 87.44300079 58.52199936 Tm [(CDC25A)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 123.22799683 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 127.72799683 58.52199936 Tm [(is)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 134.28900146 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 138.78900146 58.52199936 Tm [(speci)-1(f)1(ic)-1(ally)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 185.27400208 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 189.77400208 58.52199936 Tm [(degra)1(ded)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 231.42500305 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 235.92500305 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 243.86599731 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 248.36599731 58.52199936 Tm [(response)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 287.36300659 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 291.86300659 58.52199936 Tm [(to)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 300.93798828 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(DNA)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 20.50499916 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 25.00499916 74.12200165 Tm [(da)1(mage,)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 62.17399979 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 66.6740036 74.12200165 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 91.77100372 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 96.27100372 74.12200165 Tm [(prevents)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 133.45799255 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 137.95799255 74.12200165 Tm [(ce)-1(lls)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 156.53399658 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 161.03399658 74.12200165 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 179.42999268 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 183.92999268 74.12200165 Tm [(chromos)1(omal)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 242.98800659 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 247.48800659 74.12200165 Tm [(ab)1(n)-1(o)1(rmalities)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 306.13299561 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 20.71100044 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 25.21100044 89.72200012 Tm [(pro)1(gressing)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 76.4469986 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 80.9469986 89.72200012 Tm [(th)1(rough)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 115.84400177 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 120.34400177 89.72200012 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 134.7539978 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 139.2539978 89.72200012 Tm [(division.)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 174.52000427 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 179.02000427 89.72200012 Tm [(CDC25A)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 214.80499268 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 219.30499268 89.72200012 Tm [(is)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 225.86599731 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 230.36599731 89.72200012 Tm [(an)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 240.88699341 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 245.38699341 89.72200012 Tm [(oncogene)-1(,)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 290.57199097 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 295.07199097 89.72200012 Tm [(alt)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ho)1(u)-1(g)1(h)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 28.10700035 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 32.60699844 105.3219986 Tm [(its)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 42.52099991 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 47.02099991 105.3219986 Tm [(exact)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 69.52999878 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 74.02999878 105.3219986 Tm [(role)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 90.69000244 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 95.19000244 105.3219986 Tm [(in)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 103.1309967 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 107.6309967 105.3219986 Tm [(oncogene)-1(sis)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 161.37600708 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 165.87600708 105.3219986 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 180.55799866 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 185.05799866 105.3219986 Tm [(not)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 199.67900085 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 204.17900085 105.3219986 Tm [(been)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 225.68600464 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 230.18600464 105.3219986 Tm [(demonst)1(rated.)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 293.06298828 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 297.56298828 105.3219986 Tm [(Tw)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(o)] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 5.72200012 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 10.22200012 120.92199707 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 51.14400101 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 55.64400101 120.92199707 Tm [(var)1(i)-1(a)1(n)-1(t)1(s)] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 89.21399689 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 93.71399689 120.92199707 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 134.05599976 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 138.55599976 120.92199707 Tm [(dif)1(fe)-1(r)1(e)-1(nt)] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 175.4960022 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 179.9960022 120.92199707 Tm [(isof)1(orms)] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 217.15600586 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 221.65600586 120.92199707 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 290 >> BDC BT 1 0 0 -1 242.00300598 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 291 >> BDC BT 1 0 0 -1 246.50300598 120.92199707 Tm [(been)] TJ ET EMC /P <</MCID 292 >> BDC BT 1 0 0 -1 268.01000977 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 293 >> BDC BT 1 0 0 -1 272.51000977 120.92199707 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <</MCID 294 >> BDC BT 1 0 0 -1 298.20001221 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 295 >> BDC BT 1 0 0 -1 302.70001221 120.92199707 Tm [(f)] TJ ET EMC /P <</MCID 296 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(or)] TJ ET EMC /P <</MCID 297 >> BDC BT 1 0 0 -1 9.15799999 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 298 >> BDC BT 1 0 0 -1 13.65799999 136.52200317 Tm [(th)1(is)] TJ ET EMC /P <</MCID 299 >> BDC BT 1 0 0 -1 29.11400032 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 300 >> BDC BT 1 0 0 -1 33.61399841 136.52200317 Tm [(gene)-1(.)] TJ ET EMC /P <</MCID 301 >> BDC BT 1 0 0 -1 57.29600143 136.52200317 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 269.70001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.05000305 0.75 m 109.05000305 30.45000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.05000305 31.20000076 m 109.05000305 46.80000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.05000305 47.55000305 m 109.05000305 63.15000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.05000305 63.90000153 m 109.05000305 79.5 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.05000305 80.25 m 109.05000305 95.84999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.05000305 96.59999847 m 109.05000305 112.19999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.05000305 112.94999695 m 109.05000305 128.55000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.05000305 129.30000305 m 109.05000305 269.70001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.54998779 0.75 m 426.54998779 269.70001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 30.82500076 m 426.17498779 30.82500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 47.17500305 m 426.17498779 47.17500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 63.52500153 m 426.17498779 63.52500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 79.875 m 426.17498779 79.875 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 96.22499847 m 426.17498779 96.22499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 112.57499695 m 426.17498779 112.57499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 128.92500305 m 426.17498779 128.92500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 270.07501221 m 426.92498779 270.07501221 l S Q Q q 1 0 0 1 0 606.7789917 cm Q Q 1 0 0 -1 0 841.90002441 cm 
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