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[(QDPR)] TJ ET EMC /P <</MCID 5 >> BDC BT 1 0 0 -1 77.15000153 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 82.40000153 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 166.3999939 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(QDPR)] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 87.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 90.02400208 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 123.22599792 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 125.59999847 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 185.58000183 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 187.95399475 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 222.42799377 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 18 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 19 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(qu)-1(in)-1(oi)-1(d)] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 95.42299652 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 97.79699707 12.82499981 Tm [(di)-1(hydrop)-1(te)1(rid)-1(in)-1(e)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 169.70300293 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 172.07699585 12.82499981 Tm [(re)1(d)-1(uctase)1(;)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 217.12199402 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 219.4960022 12.82499981 Tm [(DHPR;)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 246.43299866 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 248.80700684 12.82499981 Tm [(PK)1(U2;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 274.55499268 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 276.9289856 12.82499981 Tm [(HDHPR;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 310.4079895 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 312.78201294 12.82499981 Tm [(SD)-1(R33)1(C)-1(1)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 351.33200073 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B000F>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 242.43400574 cm /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -0.64999998 270.37298584 cm q -0.75 -0.5 m 422.1000061 -0.5 l 422.1000061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 52 >> BDC q /GS2 gs 1 g 0 1.25 m 28.15600014 1.25 l 28.15600014 16.68799973 l 0 16.68799973 l h f* Q q /GS2 gs 1 g 28.15600014 1.25 m 30.81900024 1.25 l 30.81900024 16.68799973 l 28.15600014 16.68799973 l h f* Q q /GS2 gs 1 g 30.81900024 1.25 m 62.12599945 1.25 l 62.12599945 16.68799973 l 30.81900024 16.68799973 l h f* Q q /GS2 gs 1 g 62.12599945 1.25 m 64.78900146 1.25 l 64.78900146 16.68799973 l 62.12599945 16.68799973 l h f* Q q /GS2 gs 1 g 64.78900146 1.25 m 127.63999939 1.25 l 127.63999939 16.68799973 l 64.78900146 16.68799973 l h f* Q q /GS2 gs 1 g 127.63999939 1.25 m 130.30299377 1.25 l 130.30299377 16.68799973 l 127.63999939 16.68799973 l h f* Q q /GS2 gs 1 g 130.30299377 1.25 m 139.37799072 1.25 l 139.37799072 16.68799973 l 130.30299377 16.68799973 l h f* Q q /GS2 gs 1 g 139.37800598 1.25 m 142.04100037 1.25 l 142.04100037 16.68799973 l 139.37800598 16.68799973 l h f* Q q /GS2 gs 1 g 142.04100037 1.25 m 147.01600647 1.25 l 147.01600647 16.68799973 l 142.04100037 16.68799973 l h f* Q q /GS2 gs 1 g 147.01600647 1.25 m 149.67900085 1.25 l 149.67900085 16.68799973 l 147.01600647 16.68799973 l h f* Q q /GS2 gs 1 g 149.67900085 1.25 m 177.64100647 1.25 l 177.64100647 16.68799973 l 149.67900085 16.68799973 l h f* Q q /GS2 gs 1 g 177.64100647 1.25 m 180.30400085 1.25 l 180.30400085 16.68799973 l 177.64100647 16.68799973 l h f* Q q /GS2 gs 1 g 180.30400085 1.25 m 212.58599854 1.25 l 212.58599854 16.68799973 l 180.30400085 16.68799973 l h f* Q q /GS2 gs 1 g 212.58599854 1.25 m 215.24899292 1.25 l 215.24899292 16.68799973 l 212.58599854 16.68799973 l h f* Q q /GS2 gs 1 g 215.24899292 1.25 m 235.95999146 1.25 l 235.95999146 16.68799973 l 215.24899292 16.68799973 l h f* Q q /GS2 gs 1 g 235.96000671 1.25 m 238.6230011 1.25 l 238.6230011 16.68799973 l 235.96000671 16.68799973 l h f* Q q /GS2 gs 1 g 238.6230011 1.25 m 263.62799072 1.25 l 263.62799072 16.68799973 l 238.6230011 16.68799973 l h f* Q q /GS2 gs 1 g 263.62799072 1.25 m 266.29098511 1.25 l 266.29098511 16.68799973 l 263.62799072 16.68799973 l h f* Q q /GS2 gs 1 g 266.29098511 1.25 m 293.36099243 1.25 l 293.36099243 16.68799973 l 266.29098511 16.68799973 l h f* Q q /GS2 gs 1 g 293.36099243 1.25 m 296.02398682 1.25 l 296.02398682 16.68799973 l 293.36099243 16.68799973 l h f* Q q /GS2 gs 1 g 296.02398682 1.25 m 317.82998657 1.25 l 317.82998657 16.68799973 l 296.02398682 16.68799973 l h f* Q q /GS2 gs 1 g 317.82998657 1.25 m 320.49298096 1.25 l 320.49298096 16.68799973 l 317.82998657 16.68799973 l h f* Q q /GS2 gs 1 g 320.49301147 1.25 m 329.33502197 1.25 l 329.33502197 16.68799973 l 320.49301147 16.68799973 l h f* Q q /GS2 gs 1 g 329.33499146 1.25 m 331.99798584 1.25 l 331.99798584 16.68799973 l 329.33499146 16.68799973 l h f* Q q /GS2 gs 1 g 331.99798584 1.25 m 362.03900146 1.25 l 362.03900146 16.68799973 l 331.99798584 16.68799973 l h f* Q q /GS2 gs 1 g 362.03900146 1.25 m 364.70199585 1.25 l 364.70199585 16.68799973 l 362.03900146 16.68799973 l h f* Q q /GS2 gs 1 g 364.70199585 1.25 m 390.27398682 1.25 l 390.27398682 16.68799973 l 364.70199585 16.68799973 l h f* Q EMC /P <</MCID 53 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 12.89099979 Tm /GS2 gs 0.13333334 g [(Fusion)] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 28.15600014 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 30.81900024 12.89099979 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 62.12599945 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 64.78900146 12.89099979 Tm [(correspond)1(i)-1(ng)] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 127.63999939 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 130.30299377 12.89099979 Tm [(to)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 139.37800598 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 142.04100037 12.89099979 Tm [(a)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 147.01600647 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 149.67900085 12.89099979 Tm [(region)] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 177.64100647 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 180.30400085 12.89099979 Tm [(derived)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 212.58599854 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 215.24899292 12.89099979 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 235.96000671 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 238.6230011 12.89099979 Tm [(2-24)-1(4)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 263.62799072 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 266.29098511 12.89099979 Tm [(amino)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 293.36099243 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 296.02398682 12.89099979 Tm [(acids)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 317.82998657 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 320.49301147 12.89099979 Tm [(of)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 329.33499146 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 331.99798584 12.89099979 Tm [(human)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 362.03900146 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 364.70199585 12.89099979 Tm [(QDP)1(R)] TJ ET EMC /P <</MCID 80 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 390.27398682 12.89099979 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 421.3500061 0.5 m 421.3500061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 421.6000061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 421.6000061 28.68899918 l S Q Q q 1 0 0 1 0 299.31201172 cm /P <</MCID 81 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 327.25100708 cm /P <</Lang (zh-CN) /MCID 82 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F000F>] TJ ET EMC /P <</MCID 83 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 355.19000244 cm /P <</MCID 84 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 383.1289978 cm q /GS2 gs 1 g 0.375 0.75 m 156.92500305 0.75 l 156.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 157.92500305 -0.25 l 157.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 85 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 88 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 157.67500305 16.35000038 l h f* Q q 1 0 0 1 157.30000305 0 cm -0.625 -0.25 m 269.875 -0.25 l 269.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 89 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(quinoid)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 33.11700058 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 37.61700058 11.72200012 Tm [(dih)1(y)-1(d)1(ropt)1(e)-1(r)1(i)-1(d)1(in)-1(e)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 109.83200073 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 114.33200073 11.72200012 Tm [(reduc)-1(t)1(ase)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 156.29100037 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 156.92500305 0.75 l 156.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 157.92500305 -0.25 l 157.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 95 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 96 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 157.67500305 16.35000038 l h f* Q q 1 0 0 1 157.30000305 0 cm -0.625 -0.25 m 269.875 -0.25 l 269.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 97 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(DHPR;)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 27.36499977 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 31.86499977 11.72200012 Tm [(PKU)1(2)-1(;)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 57.2480011 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 61.7480011 11.72200012 Tm [(HDH)-1(P)1(R;)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 96.0739975 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 100.5739975 11.72200012 Tm [(SDR33)-1(C)1(1)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 140.35299683 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 156.92500305 0.75 l 156.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 157.92500305 -0.25 l 157.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 105 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 106 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 157.67500305 16.35000038 l h f* Q q 1 0 0 1 157.30000305 0 cm -0.625 -0.25 m 269.875 -0.25 l 269.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 107 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(P09)-1(41)-1(7)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 31.89599991 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 156.92500305 0.75 l 156.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 157.92500305 -0.25 l 157.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 109 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 112 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 157.67500305 16.35000038 l h f* Q q 1 0 0 1 157.30000305 0 cm -0.625 -0.25 m 269.875 -0.25 l 269.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 113 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(00)-1(57)-1(6)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 156.92500305 0.75 l 156.92500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 157.92500305 -0.25 l 157.92500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 115 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 116 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 29.68899918 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.67500305 0.75 m 426.17498779 0.75 l 426.17498779 31.95000076 l 157.67500305 31.95000076 l h f* Q q 1 0 0 1 157.30000305 0 cm -0.625 -0.25 m 269.875 -0.25 l 269.875 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 117 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(A)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(GE)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 11.64099979 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 97.34999847 cm q /GS2 gs 1 g 0.375 0.75 m 156.92500305 0.75 l 156.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 157.92500305 -0.25 l 157.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 134 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 137 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 157.67500305 16.35000038 l h f* Q q 1 0 0 1 157.30000305 0 cm -0.625 -0.25 m 269.875 -0.25 l 269.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 138 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 113.69999695 cm q /GS2 gs 1 g 0.375 0.75 m 156.92500305 0.75 l 156.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 157.92500305 -0.25 l 157.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 142 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 143 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 157.67500305 16.35000038 l h f* Q q 1 0 0 1 157.30000305 0 cm -0.625 -0.25 m 269.875 -0.25 l 269.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 144 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 130.05000305 cm q /GS2 gs 1 g 0.375 0.75 m 156.92500305 0.75 l 156.92500305 94.34999847 l 0.375 94.34999847 l h f* Q q -0.625 -0.25 m 157.92500305 -0.25 l 157.92500305 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 156 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 50.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 157 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 57.29199982 50.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.67500305 0.75 m 426.17498779 0.75 l 426.17498779 94.34999847 l 157.67500305 94.34999847 l h f* Q q 1 0 0 1 157.30000305 0 cm -0.625 -0.25 m 269.875 -0.25 l 269.875 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 158 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 102.19599915 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 106.69599915 11.72200012 Tm [(en)-1(z)1(y)-1(me)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 140.07699585 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 144.57699585 11.72200012 Tm [(dih)1(y)-1(d)1(ropt)1(e)-1(r)1(i)-1(d)1(in)-1(e)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 216.79200745 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 221.29200745 11.72200012 Tm [(reduc)-1(t)1(as)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(e,)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 7.27299976 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 11.77299976 27.3220005 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 36.86999893 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 41.36999893 27.3220005 Tm [(cata)1(l)-1(yzes)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 80.04199982 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 84.54199982 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 98.54299927 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 103.04299927 27.3220005 Tm [(NAD)1(H)-1(-)1(me)-1(d)1(i)-1(a)1(ted)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 175.28500366 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 179.78500366 27.3220005 Tm [(reduc)-1(t)1(ion)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 221.16000366 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 225.66000366 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 234.5019989 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 239.0019989 27.3220005 Tm [(quin)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(onoid)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 25.14100075 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 29.64100075 42.92200089 Tm [(dih)1(y)-1(d)1(robiop)1(terin.)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 104.6289978 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 109.1289978 42.92200089 Tm [(This)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 126.39099884 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 130.89100647 42.92200089 Tm [(en)-1(z)1(y)-1(me)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 164.27200317 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 168.77200317 42.92200089 Tm [(is)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 175.33299255 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 179.83299255 42.92200089 Tm [(an)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 190.35400391 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 194.85400391 42.92200089 Tm [(esse)-1(nt)1(ial)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 232.06199646 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 236.56199646 42.92200089 Tm [(comp)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(onen)-1(t)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 25.27300072 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 29.77300072 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 38.61500168 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 43.11500168 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 57.11600113 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 61.61600113 58.52199936 Tm [(pt)1(e)-1(r)1(i)-1(n-)1(depen)-1(d)1(e)-1(nt)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 138.11999512 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 142.61999512 58.52199936 Tm [(aro)1(matic)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 180.42199707 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 184.92199707 58.52199936 Tm [(amino)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 211.99200439 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 216.49200439 58.52199936 Tm [(acid)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 234.13200378 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 238.63200378 58.52199936 Tm [(hydr)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(oxylat)1(in)-1(g)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 39.46699905 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 43.96699905 74.12200165 Tm [(systems.)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 80.28800201 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 84.78800201 74.12200165 Tm [(Mutat)1(ions)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 128.63699341 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 133.13699341 74.12200165 Tm [(in)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 141.07800293 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 145.57800293 74.12200165 Tm [(th)1(is)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 161.03399658 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 165.53399658 74.12200165 Tm [(gene)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 187.05000305 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 191.55000305 74.12200165 Tm [(resulting)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 229.25100708 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 233.75100708 74.12200165 Tm [(in)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 241.69200134 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 246.19200134 74.12200165 Tm [(QD)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(PR)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 11.38199997 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 15.88199997 89.72200012 Tm [(deficie)-1(ncy)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 59.09799957 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 63.59799957 89.72200012 Tm [(inc)-1(lude)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 94.85600281 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 99.35600281 89.72200012 Tm [(ab)1(e)-1(rr)1(ant)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 135.93200684 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 140.43200684 89.72200012 Tm [(splicin)-1(g)1(,)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 175.51400757 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 180.01400757 89.72200012 Tm [(amino)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 207.08399963 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 211.58399963 89.72200012 Tm [(acid)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 229.22399902 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 233.72399902 89.72200012 Tm [(subst)1(i)] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 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