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[(PN)1(RC2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 83.9489975 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 167.94900513 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(PN)1(RC2)] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 91.8239975 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 94.19799805 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 127.40000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 129.77400208 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 189.7539978 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 192.12800598 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 226.602005 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 17 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 18 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 19 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0012000F>] TJ ET EMC /P <</MCID 20 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001300140005>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0015000A>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 25 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0016001700180019000F>] TJ ET EMC /P <</MCID 26 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 27 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 28 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 29 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 30 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B000F>] TJ ET EMC /P <</MCID 31 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 208.89500427 cm /P <</MCID 32 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -0.64999998 236.83399963 cm q -0.75 -0.5 m 422.1000061 -0.5 l 422.1000061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 33 >> BDC q /GS2 gs 1 g 0 1.25 m 28.15600014 1.25 l 28.15600014 16.68799973 l 0 16.68799973 l h f* Q q /GS2 gs 1 g 28.15600014 1.25 m 30.81900024 1.25 l 30.81900024 16.68799973 l 28.15600014 16.68799973 l h f* Q q /GS2 gs 1 g 30.81900024 1.25 m 62.12599945 1.25 l 62.12599945 16.68799973 l 30.81900024 16.68799973 l h f* Q q /GS2 gs 1 g 62.12599945 1.25 m 64.78900146 1.25 l 64.78900146 16.68799973 l 62.12599945 16.68799973 l h f* Q q /GS2 gs 1 g 64.78900146 1.25 m 127.63999939 1.25 l 127.63999939 16.68799973 l 64.78900146 16.68799973 l h f* Q q /GS2 gs 1 g 127.63999939 1.25 m 130.30299377 1.25 l 130.30299377 16.68799973 l 127.63999939 16.68799973 l h f* Q q /GS2 gs 1 g 130.30299377 1.25 m 139.37799072 1.25 l 139.37799072 16.68799973 l 130.30299377 16.68799973 l h f* Q q /GS2 gs 1 g 139.37800598 1.25 m 142.04100037 1.25 l 142.04100037 16.68799973 l 139.37800598 16.68799973 l h f* Q q /GS2 gs 1 g 142.04100037 1.25 m 147.01600647 1.25 l 147.01600647 16.68799973 l 142.04100037 16.68799973 l h f* Q q /GS2 gs 1 g 147.01600647 1.25 m 149.67900085 1.25 l 149.67900085 16.68799973 l 147.01600647 16.68799973 l h f* Q q /GS2 gs 1 g 149.67900085 1.25 m 177.64100647 1.25 l 177.64100647 16.68799973 l 149.67900085 16.68799973 l h f* Q q /GS2 gs 1 g 177.64100647 1.25 m 180.30400085 1.25 l 180.30400085 16.68799973 l 177.64100647 16.68799973 l h f* Q q /GS2 gs 1 g 180.30400085 1.25 m 212.58599854 1.25 l 212.58599854 16.68799973 l 180.30400085 16.68799973 l h f* Q q /GS2 gs 1 g 212.58599854 1.25 m 215.24899292 1.25 l 215.24899292 16.68799973 l 212.58599854 16.68799973 l h f* Q q /GS2 gs 1 g 215.24899292 1.25 m 235.95999146 1.25 l 235.95999146 16.68799973 l 215.24899292 16.68799973 l h f* Q q /GS2 gs 1 g 235.96000671 1.25 m 238.6230011 1.25 l 238.6230011 16.68799973 l 235.96000671 16.68799973 l h f* Q q /GS2 gs 1 g 238.6230011 1.25 m 263.62799072 1.25 l 263.62799072 16.68799973 l 238.6230011 16.68799973 l h f* Q q /GS2 gs 1 g 263.62799072 1.25 m 266.29098511 1.25 l 266.29098511 16.68799973 l 263.62799072 16.68799973 l h f* Q q /GS2 gs 1 g 266.29098511 1.25 m 293.36099243 1.25 l 293.36099243 16.68799973 l 266.29098511 16.68799973 l h f* Q q /GS2 gs 1 g 293.36099243 1.25 m 296.02398682 1.25 l 296.02398682 16.68799973 l 293.36099243 16.68799973 l h f* Q q /GS2 gs 1 g 296.02398682 1.25 m 317.82998657 1.25 l 317.82998657 16.68799973 l 296.02398682 16.68799973 l h f* Q q /GS2 gs 1 g 317.82998657 1.25 m 320.49298096 1.25 l 320.49298096 16.68799973 l 317.82998657 16.68799973 l h f* Q q /GS2 gs 1 g 320.49301147 1.25 m 329.33502197 1.25 l 329.33502197 16.68799973 l 320.49301147 16.68799973 l h f* Q q /GS2 gs 1 g 329.33499146 1.25 m 331.99798584 1.25 l 331.99798584 16.68799973 l 329.33499146 16.68799973 l h f* Q q /GS2 gs 1 g 331.99798584 1.25 m 362.03900146 1.25 l 362.03900146 16.68799973 l 331.99798584 16.68799973 l h f* Q q /GS2 gs 1 g 362.03900146 1.25 m 364.70199585 1.25 l 364.70199585 16.68799973 l 362.03900146 16.68799973 l h f* Q q /GS2 gs 1 g 364.70199585 1.25 m 394.69900513 1.25 l 394.69900513 16.68799973 l 364.70199585 16.68799973 l h f* Q EMC /P <</MCID 34 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 12.89099979 Tm /GS2 gs 0.13333334 g [(Fusion)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 28.15600014 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 30.81900024 12.89099979 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 62.12599945 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 64.78900146 12.89099979 Tm [(correspond)1(i)-1(ng)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 127.63999939 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 130.30299377 12.89099979 Tm [(to)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 139.37800598 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 142.04100037 12.89099979 Tm [(a)] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 147.01600647 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 149.67900085 12.89099979 Tm [(region)] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 177.64100647 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 180.30400085 12.89099979 Tm [(derived)] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 212.58599854 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 215.24899292 12.89099979 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 235.96000671 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 238.6230011 12.89099979 Tm [(1-13)-1(9)] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 263.62799072 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 266.29098511 12.89099979 Tm [(amino)] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 293.36099243 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 296.02398682 12.89099979 Tm [(acids)] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 317.82998657 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 320.49301147 12.89099979 Tm [(of)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 329.33499146 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 331.99798584 12.89099979 Tm [(human)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 362.03900146 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 364.70199585 12.89099979 Tm [(PNRC2)] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 394.69900513 12.89099979 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 421.3500061 0.5 m 421.3500061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 421.6000061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 421.6000061 28.68899918 l S Q Q q 1 0 0 1 0 265.77301025 cm /P <</MCID 62 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 293.71200562 cm /P <</Lang (zh-CN) /MCID 63 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F000F>] TJ ET EMC /P <</MCID 64 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 321.65100098 cm /P <</MCID 65 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 349.58999634 cm q /GS2 gs 1 g 0.375 0.75 m 95.625 0.75 l 95.625 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 96.625 -0.25 l 96.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 66 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 69 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 96.375 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 96.375 16.35000038 l h f* Q q 1 0 0 1 96 0 cm -0.625 -0.25 m 331.17498779 -0.25 l 331.17498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 70 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(pro)1(lin)-1(e)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 30.34900093 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 34.84899902 11.72200012 Tm [(rich)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 50.73500061 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 55.23500061 11.72200012 Tm [(nuc)-1(lear)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 86.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 91.25299835 11.72200012 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 127.67500305 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 132.17500305 11.72200012 Tm [(coactivat)1(or)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 179.85600281 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 184.35600281 11.72200012 Tm [(2)] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 189.63400269 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 95.625 0.75 l 95.625 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 96.625 -0.25 l 96.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 82 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 83 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 96.375 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 96.375 16.35000038 l h f* Q q 1 0 0 1 96 0 cm -0.625 -0.25 m 331.17498779 -0.25 l 331.17498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 84 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q9NPJ4)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 34.27700043 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 95.625 0.75 l 95.625 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 96.625 -0.25 l 96.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 86 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 96.375 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 96.375 16.35000038 l h f* Q q 1 0 0 1 96 0 cm -0.625 -0.25 m 331.17498779 -0.25 l 331.17498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 90 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(01)-1(95)-1(9)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 95.625 0.75 l 95.625 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 96.625 -0.25 l 96.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 92 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 93 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 96.375 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 96.375 16.35000038 l h f* Q q 1 0 0 1 96 0 cm -0.625 -0.25 m 331.17498779 -0.25 l 331.17498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 94 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 95.625 0.75 l 95.625 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 96.625 -0.25 l 96.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 110 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 113 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 96.375 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 96.375 16.35000038 l h f* Q q 1 0 0 1 96 0 cm -0.625 -0.25 m 331.17498779 -0.25 l 331.17498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 114 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 95.625 0.75 l 95.625 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 96.625 -0.25 l 96.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 118 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 119 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 96.375 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 96.375 16.35000038 l h f* Q q 1 0 0 1 96 0 cm -0.625 -0.25 m 331.17498779 -0.25 l 331.17498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 120 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 95.625 0.75 l 95.625 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 96.625 -0.25 l 96.625 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 132 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 133 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 96.375 0.75 m 426.17498779 0.75 l 426.17498779 172.3500061 l 96.375 172.3500061 l h f* Q q 1 0 0 1 96 0 cm -0.625 -0.25 m 331.17498779 -0.25 l 331.17498779 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 134 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Involved)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 36.61999893 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 41.11999893 11.72200012 Tm [(in)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 49.06100082 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 53.56100082 11.72200012 Tm [(nonsen)-1(se-media)1(ted)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 139.24099731 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 143.74099731 11.72200012 Tm [(mRNA)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 171.69900513 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 176.19900513 11.72200012 Tm [(decay)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 201.31399536 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 205.81399536 11.72200012 Tm [(\(NMD\))] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 234.79200745 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 239.29200745 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 249.80400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 254.30400085 11.72200012 Tm [(acting)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 280.84298706 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 285.34298706 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 294.48400879 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 298.98400879 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 303.95901489 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 308.45901489 11.72200012 Tm [(bri)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(dg)1(e)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 16.62000084 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 21.12000084 27.3220005 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 58.19200134 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 62.69200134 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 76.69300079 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 81.19300079 27.3220005 Tm [(mRNA)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 109.15100098 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 113.65100098 27.3220005 Tm [(decapping)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 159.19599915 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 163.69599915 27.3220005 Tm [(complex)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 200.17500305 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 204.67500305 27.3220005 Tm [(and)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 220.95199585 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 225.45199585 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 239.45300293 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 243.95300293 27.3220005 Tm [(NMD)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 266.91900635 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 271.41900635 27.3220005 Tm [(machine)-1(r)1(y)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 316.1289978 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(\(PubMed:)1(1)-1(91)-1(50)-1(429)-1(\).)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 89.02400208 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 93.52400208 42.92200089 Tm [(May)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 112.05599976 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 116.55599976 42.92200089 Tm [(act)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 129.39700317 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 133.89700317 42.92200089 Tm [(by)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 144.40899658 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 148.90899658 42.92200089 Tm [(ta)1(rgeting)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 188.58700562 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 193.08700562 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 207.08799744 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 211.58799744 42.92200089 Tm [(NMD)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 234.55400085 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 239.05400085 42.92200089 Tm [(machine)-1(r)1(y)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 283.76400757 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 288.26400757 42.92200089 Tm [(to)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 297.33898926 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 301.83898926 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 315.83999634 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(P-)1(bod)1(y)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 31.38999939 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 35.88999939 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 52.16699982 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 56.66699982 58.52199936 Tm [(rec)-1(ruit)1(i)-1(ng)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 98.15100098 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 102.65100098 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 116.65200043 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 121.15200043 58.52199936 Tm [(decapping)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 166.69700623 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 171.19700623 58.52199936 Tm [(machine)-1(r)1(y)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 215.90699768 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 220.40699768 58.52199936 Tm [(to)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 229.48199463 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 233.98199463 58.52199936 Tm [(ab)1(e)-1(rr)1(ant)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 270.55801392 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 275.05801392 58.52199936 Tm [(mRNA)1(s)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 307.18200684 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 311.68200684 58.52199936 Tm [(\(P)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ubMed:19)-1(150)-1(42)-1(9\).)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 80.51200104 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 85.01200104 74.12200165 Tm [(Required)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 123.99099731 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 128.49099731 74.12200165 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 140.76899719 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 145.26899719 74.12200165 Tm [(UP)1(F)-1(1/RENT1)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 199.977005 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 204.477005 74.12200165 Tm [(localizat)1(ion)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 253.28700256 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 257.7869873 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 266.86199951 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 271.36199951 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 285.36300659 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 289.86300659 74.12200165 Tm [(P-)1(bod)1(y)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 321.25299072 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(\(PubMed:)1(1)-1(91)-1(50)-1(429)-1(\).)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 89.02400208 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 93.52400208 89.72200012 Tm [(Plays)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 115.33000183 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 119.83000183 89.72200012 Tm [(a)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 124.80500031 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 129.30499268 89.72200012 Tm [(role)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 145.96499634 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 150.46499634 89.72200012 Tm [(in)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 158.40600586 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 162.90600586 89.72200012 Tm [(glucoc)-1(o)1(rticoid)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 224.64500427 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 229.14500427 89.72200012 Tm [(rec)-1(ept)1(or-)1(m)-1(edia)1(ted)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 310.34298706 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(mRNA)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 27.95800018 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 32.45800018 105.3219986 Tm [(degra)1(dat)1(ion)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 85.23600006 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 89.73600006 105.3219986 Tm [(by)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 100.2480011 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 104.7480011 105.3219986 Tm [(interacting)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 151.1230011 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 155.6230011 105.3219986 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 174.01899719 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 178.51899719 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 192.52000427 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 197.02000427 105.3219986 Tm [(glucoc)-1(o)1(rticoid)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 258.75900269 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 263.25900269 105.3219986 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 299.68099976 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 304.18099976 105.3219986 Tm [(NR3)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(C1)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 11.29800034 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 15.79800034 120.92199707 Tm [(in)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 23.73900032 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 28.23900032 120.92199707 Tm [(a)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 33.2140007 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 37.7140007 120.92199707 Tm [(ligand)1(-dependen)-1(t)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 115.45800018 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 119.95800018 120.92199707 Tm [(manne)-1(r)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 153 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 157.5 120.92199707 Tm [(wh)1(e)-1(n)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 180.80000305 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 185.30000305 120.92199707 Tm [(it)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 191.04800415 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 195.54800415 120.92199707 Tm [(is)] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 202.10899353 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 206.60899353 120.92199707 Tm [(bo)1(u)-1(nd)] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 234.92700195 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 239.42700195 120.92199707 Tm [(to)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 248.5019989 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 253.0019989 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 267.00299072 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 271.50299072 120.92199707 Tm [(5')] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 279.0880127 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 283.5880127 120.92199707 Tm [(UTR)] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 301.3420105 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 305.8420105 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 314.68399048 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 319.18399048 120.92199707 Tm [(t)] TJ ET EMC /P <</MCID 290 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(arg)1(e)-1(t)] TJ ET EMC /P <</MCID 291 >> BDC BT 1 0 0 -1 22.62700081 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 292 >> BDC BT 1 0 0 -1 27.12700081 136.52200317 Tm [(mRNA)1(s)] TJ ET EMC /P <</MCID 293 >> BDC BT 1 0 0 -1 59.25099945 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 294 >> BDC BT 1 0 0 -1 63.75099945 136.52200317 Tm [(and)] TJ ET EMC /P <</MCID 295 >> BDC BT 1 0 0 -1 80.02799988 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 296 >> BDC BT 1 0 0 -1 84.52799988 136.52200317 Tm [(rec)-1(ruit)1(i)-1(ng)] TJ ET EMC /P <</MCID 297 >> BDC BT 1 0 0 -1 126.01200104 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 298 >> BDC BT 1 0 0 -1 130.51199341 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <</MCID 299 >> BDC BT 1 0 0 -1 144.51300049 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 300 >> BDC BT 1 0 0 -1 149.01300049 136.52200317 Tm [(RNA)] TJ ET EMC /P <</MCID 301 >> BDC BT 1 0 0 -1 168.53799438 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 302 >> BDC BT 1 0 0 -1 173.03799438 136.52200317 Tm [(helic)-1(as)1(e)] TJ ET EMC /P <</MCID 303 >> BDC BT 1 0 0 -1 207.23599243 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 304 >> BDC BT 1 0 0 -1 211.73599243 136.52200317 Tm [(UP)1(F)-1(1)] TJ ET EMC /P <</MCID 305 >> BDC BT 1 0 0 -1 234.02099609 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 306 >> BDC BT 1 0 0 -1 238.52099609 136.52200317 Tm [(and)] TJ ET EMC /P <</MCID 307 >> BDC BT 1 0 0 -1 254.79800415 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 308 >> BDC BT 1 0 0 -1 259.29800415 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <</MCID 309 >> BDC BT 1 0 0 -1 273.29901123 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 310 >> BDC BT 1 0 0 -1 277.79901123 136.52200317 Tm [(mRNA)1(-de)] TJ ET EMC /P <</MCID 311 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(capping)] TJ ET EMC /P <</MCID 312 >> BDC BT 1 0 0 -1 34.68199921 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 313 >> BDC BT 1 0 0 -1 39.18199921 152.12199402 Tm [(en)-1(z)1(y)-1(me)] TJ ET EMC /P <</MCID 314 >> BDC BT 1 0 0 -1 72.56300354 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 315 >> BDC BT 1 0 0 -1 77.06300354 152.12199402 Tm [(DCP)1(1)-1(A,)] TJ ET EMC /P <</MCID 316 >> BDC BT 1 0 0 -1 109.22200012 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 317 >> BDC BT 1 0 0 -1 113.72200012 152.12199402 Tm [(leading)] TJ ET EMC /P <</MCID 318 >> BDC BT 1 0 0 -1 145.65299988 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 319 >> BDC BT 1 0 0 -1 150.15299988 152.12199402 Tm [(to)] TJ ET EMC /P <</MCID 320 >> BDC BT 1 0 0 -1 159.22799683 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 321 >> BDC BT 1 0 0 -1 163.72799683 152.12199402 Tm [(RNA)] TJ ET EMC /P <</MCID 322 >> BDC BT 1 0 0 -1 183.25300598 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 323 >> BDC BT 1 0 0 -1 187.75300598 152.12199402 Tm [(decay)] TJ ET EMC /P <</MCID 324 >> BDC BT 1 0 0 -1 212.86799622 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 325 >> BDC BT 1 0 0 -1 217.36799622 152.12199402 Tm [(\(PubMed:)1(2)-1(57)-1(75)-1(514)-1(\).)] TJ ET EMC /P <</MCID 326 >> BDC BT 1 0 0 -1 306.39199829 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 327 >> BDC BT 1 0 0 -1 310.89199829 152.12199402 Tm [(Al)] TJ ET EMC /P <</MCID 328 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(so)] TJ ET EMC /P <</MCID 329 >> BDC BT 1 0 0 -1 9.88799953 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 330 >> BDC BT 1 0 0 -1 14.38799953 167.72200012 Tm [(acts)] TJ ET EMC /P <</MCID 331 >> BDC BT 1 0 0 -1 31.39500046 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 332 >> BDC BT 1 0 0 -1 35.89500046 167.72200012 Tm [(as)] TJ ET EMC /P <</MCID 333 >> BDC BT 1 0 0 -1 45.0359993 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 334 >> BDC BT 1 0 0 -1 49.5359993 167.72200012 Tm [(a)] TJ ET EMC /P <</MCID 335 >> BDC BT 1 0 0 -1 54.51100159 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 336 >> BDC BT 1 0 0 -1 59.01100159 167.72200012 Tm [(nuc)-1(lear)] TJ ET EMC /P <</MCID 337 >> BDC BT 1 0 0 -1 90.52899933 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 338 >> BDC BT 1 0 0 -1 95.02899933 167.72200012 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 339 >> BDC BT 1 0 0 -1 131.45100403 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 340 >> BDC BT 1 0 0 -1 135.95100403 167.72200012 Tm [(coactivat)1(or)] TJ ET EMC /P <</MCID 341 >> BDC BT 1 0 0 -1 183.63200378 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 342 >> BDC BT 1 0 0 -1 188.13200378 167.72200012 Tm [(\(PubMed:)1(1)-1(15)-1(74)-1(675)-1(\).)] TJ ET EMC /P <</MCID 343 >> BDC BT 1 0 0 -1 277.15600586 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 344 >> BDC BT 1 0 0 -1 281.65600586 167.72200012 Tm [(May)] TJ ET EMC /P <</MCID 345 >> BDC BT 1 0 0 -1 300.18798828 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 346 >> BDC BT 1 0 0 -1 304.68798828 167.72200012 Tm [(play)] TJ ET EMC /P <</MCID 347 >> BDC BT 1 0 0 -1 322.56900024 167.72200012 Tm [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 270.45001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 96 0.75 m 96 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 96 17.10000038 m 96 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 96 33.45000076 m 96 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 96 49.80000305 m 96 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 96 66.15000153 m 96 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 96 82.5 m 96 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 96 98.84999847 m 96 270.45001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.54998779 0.75 m 426.54998779 270.45001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17498779 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 270.82501221 m 426.92498779 270.82501221 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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