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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 87.21099854 23.67700005 Tm 0 g [(FARP2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 1 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 151.38499451 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 328.08898926 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 3 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 4 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(FARP2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 82.47200012 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 166.47200012 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(FARP2)] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 90.34700012 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 92.72100067 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 125.92299652 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 128.29699707 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 188.2769928 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 190.65100098 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 225.125 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 17 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 18 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 19 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 20 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(FIR;)] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 78.98100281 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 81.35500336 12.82499981 Tm [(FRG;)] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 101.31400299 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 103.68800354 12.82499981 Tm [(PLEKHC3)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 141.57099915 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 27 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <</MCID 28 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 29 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <</MCID 30 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 31 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <</MCID 32 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 33 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <</MCID 34 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 35 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 37 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 38 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B000F>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 242.43400574 cm /P <</MCID 42 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -0.64999998 270.37298584 cm q -0.75 -0.5 m 422.1000061 -0.5 l 422.1000061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 43 >> BDC q /GS2 gs 1 g 0 1.25 m 28.15600014 1.25 l 28.15600014 16.68799973 l 0 16.68799973 l h f* Q q /GS2 gs 1 g 28.15600014 1.25 m 30.81900024 1.25 l 30.81900024 16.68799973 l 28.15600014 16.68799973 l h f* Q q /GS2 gs 1 g 30.81900024 1.25 m 62.12599945 1.25 l 62.12599945 16.68799973 l 30.81900024 16.68799973 l h f* Q q /GS2 gs 1 g 62.12599945 1.25 m 64.78900146 1.25 l 64.78900146 16.68799973 l 62.12599945 16.68799973 l h f* Q q /GS2 gs 1 g 64.78900146 1.25 m 127.63999939 1.25 l 127.63999939 16.68799973 l 64.78900146 16.68799973 l h f* Q q /GS2 gs 1 g 127.63999939 1.25 m 130.30299377 1.25 l 130.30299377 16.68799973 l 127.63999939 16.68799973 l h f* Q q /GS2 gs 1 g 130.30299377 1.25 m 139.37799072 1.25 l 139.37799072 16.68799973 l 130.30299377 16.68799973 l h f* Q q /GS2 gs 1 g 139.37800598 1.25 m 142.04100037 1.25 l 142.04100037 16.68799973 l 139.37800598 16.68799973 l h f* Q q /GS2 gs 1 g 142.04100037 1.25 m 147.01600647 1.25 l 147.01600647 16.68799973 l 142.04100037 16.68799973 l h f* Q q /GS2 gs 1 g 147.01600647 1.25 m 149.67900085 1.25 l 149.67900085 16.68799973 l 147.01600647 16.68799973 l h f* Q q /GS2 gs 1 g 149.67900085 1.25 m 177.64100647 1.25 l 177.64100647 16.68799973 l 149.67900085 16.68799973 l h f* Q q /GS2 gs 1 g 177.64100647 1.25 m 180.30400085 1.25 l 180.30400085 16.68799973 l 177.64100647 16.68799973 l h f* Q q /GS2 gs 1 g 180.30400085 1.25 m 212.58599854 1.25 l 212.58599854 16.68799973 l 180.30400085 16.68799973 l h f* Q q /GS2 gs 1 g 212.58599854 1.25 m 215.24899292 1.25 l 215.24899292 16.68799973 l 212.58599854 16.68799973 l h f* Q q /GS2 gs 1 g 215.24899292 1.25 m 235.95999146 1.25 l 235.95999146 16.68799973 l 215.24899292 16.68799973 l h f* Q q /GS2 gs 1 g 235.96000671 1.25 m 238.6230011 1.25 l 238.6230011 16.68799973 l 235.96000671 16.68799973 l h f* Q q /GS2 gs 1 g 238.6230011 1.25 m 263.62799072 1.25 l 263.62799072 16.68799973 l 238.6230011 16.68799973 l h f* Q q /GS2 gs 1 g 263.62799072 1.25 m 266.29098511 1.25 l 266.29098511 16.68799973 l 263.62799072 16.68799973 l h f* Q q /GS2 gs 1 g 266.29098511 1.25 m 293.36099243 1.25 l 293.36099243 16.68799973 l 266.29098511 16.68799973 l h f* Q q /GS2 gs 1 g 293.36099243 1.25 m 296.02398682 1.25 l 296.02398682 16.68799973 l 293.36099243 16.68799973 l h f* Q q /GS2 gs 1 g 296.02398682 1.25 m 317.82998657 1.25 l 317.82998657 16.68799973 l 296.02398682 16.68799973 l h f* Q q /GS2 gs 1 g 317.82998657 1.25 m 320.49298096 1.25 l 320.49298096 16.68799973 l 317.82998657 16.68799973 l h f* Q q /GS2 gs 1 g 320.49301147 1.25 m 329.33502197 1.25 l 329.33502197 16.68799973 l 320.49301147 16.68799973 l h f* Q q /GS2 gs 1 g 329.33499146 1.25 m 331.99798584 1.25 l 331.99798584 16.68799973 l 329.33499146 16.68799973 l h f* Q q /GS2 gs 1 g 331.99798584 1.25 m 362.03900146 1.25 l 362.03900146 16.68799973 l 331.99798584 16.68799973 l h f* Q q /GS2 gs 1 g 362.03900146 1.25 m 364.70199585 1.25 l 364.70199585 16.68799973 l 362.03900146 16.68799973 l h f* Q q /GS2 gs 1 g 364.70199585 1.25 m 392.4750061 1.25 l 392.4750061 16.68799973 l 364.70199585 16.68799973 l h f* Q EMC /P <</MCID 44 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 12.89099979 Tm /GS2 gs 0.13333334 g [(Fusion)] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 28.15600014 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 30.81900024 12.89099979 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 62.12599945 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 64.78900146 12.89099979 Tm [(correspond)1(i)-1(ng)] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 127.63999939 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 130.30299377 12.89099979 Tm [(to)] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 139.37800598 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 142.04100037 12.89099979 Tm [(a)] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 147.01600647 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 149.67900085 12.89099979 Tm [(region)] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 177.64100647 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 180.30400085 12.89099979 Tm [(derived)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 212.58599854 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 215.24899292 12.89099979 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 235.96000671 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 238.6230011 12.89099979 Tm [(1-20)-1(0)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 263.62799072 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 266.29098511 12.89099979 Tm [(amino)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 293.36099243 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 296.02398682 12.89099979 Tm [(acids)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 317.82998657 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 320.49301147 12.89099979 Tm [(of)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 329.33499146 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 331.99798584 12.89099979 Tm [(human)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 362.03900146 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 364.70199585 12.89099979 Tm [(FARP2)] TJ ET EMC /P <</MCID 71 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 392.4750061 12.89099979 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 421.3500061 0.5 m 421.3500061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 421.6000061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 421.6000061 28.68899918 l S Q Q q 1 0 0 1 0 299.31201172 cm /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 327.25100708 cm /P <</Lang (zh-CN) /MCID 73 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F000F>] TJ ET EMC /P <</MCID 74 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 355.19000244 cm /P <</MCID 75 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 383.1289978 cm q /GS2 gs 1 g 0.375 0.75 m 112.67500305 0.75 l 112.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 113.67500305 -0.25 l 113.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 76 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 79 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 113.42500305 16.35000038 l h f* Q q 1 0 0 1 113.05000305 0 cm -0.625 -0.25 m 314.125 -0.25 l 314.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 80 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(FERM,)] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 26.56500053 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 31.06500053 11.72200012 Tm [(AR)1(H)-1(/Rho)1(GEF)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 87.63999939 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 92.13999939 11.72200012 Tm [(and)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 108.41699982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 112.91699982 11.72200012 Tm [(plec)-1(kstr)1(in)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 154.47599792 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 158.97599792 11.72200012 Tm [(do)1(main)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 191.80299377 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 196.30299377 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 227.61000061 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 232.11000061 11.72200012 Tm [(2)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 237.38800049 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 112.67500305 0.75 l 112.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 113.67500305 -0.25 l 113.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 94 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 95 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 113.42500305 16.35000038 l h f* Q q 1 0 0 1 113.05000305 0 cm -0.625 -0.25 m 314.125 -0.25 l 314.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 96 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(FIR;)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 15.46899986 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 19.96899986 11.72200012 Tm [(FRG;)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 39.48500061 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 43.98500061 11.72200012 Tm [(PLEKHC3)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 83.02999878 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 112.67500305 0.75 l 112.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 113.67500305 -0.25 l 113.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 102 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 103 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 113.42500305 16.35000038 l h f* Q q 1 0 0 1 113.05000305 0 cm -0.625 -0.25 m 314.125 -0.25 l 314.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 104 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(O94)-1(88)-1(7)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 33.72399902 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 112.67500305 0.75 l 112.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 113.67500305 -0.25 l 113.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 106 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 109 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 113.42500305 16.35000038 l h f* Q q 1 0 0 1 113.05000305 0 cm -0.625 -0.25 m 314.125 -0.25 l 314.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 110 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(21)-1(30)-1(1)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 112.67500305 0.75 l 112.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 113.67500305 -0.25 l 113.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 112 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 113 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 113.42500305 16.35000038 l h f* Q q 1 0 0 1 113.05000305 0 cm -0.625 -0.25 m 314.125 -0.25 l 314.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 114 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 112.67500305 0.75 l 112.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 113.67500305 -0.25 l 113.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 130 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 133 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 113.42500305 16.35000038 l h f* Q q 1 0 0 1 113.05000305 0 cm -0.625 -0.25 m 314.125 -0.25 l 314.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 134 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 112.67500305 0.75 l 112.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 113.67500305 -0.25 l 113.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 138 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 139 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 113.42500305 16.35000038 l h f* Q q 1 0 0 1 113.05000305 0 cm -0.625 -0.25 m 314.125 -0.25 l 314.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 140 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 112.67500305 0.75 l 112.67500305 109.94999695 l 0.375 109.94999695 l h f* Q q -0.625 -0.25 m 113.67500305 -0.25 l 113.67500305 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 152 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 58.52199936 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 153 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 57.29199982 58.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.42500305 0.75 m 426.17498779 0.75 l 426.17498779 109.94999695 l 113.42500305 109.94999695 l h f* Q q 1 0 0 1 113.05000305 0 cm -0.625 -0.25 m 314.125 -0.25 l 314.125 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 154 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Fun)-1(ctions)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 41.56800079 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 46.06800079 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 55.20899963 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 59.70899963 11.72200012 Tm [(guanine)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 94.58000183 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 99.08000183 11.72200012 Tm [(nuc)-1(leotid)1(e)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 144.51899719 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 149.01899719 11.72200012 Tm [(exc)-1(h)1(ange)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 190.125 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 194.625 11.72200012 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 219.7440033 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 224.2440033 11.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 241.46600342 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 245.96600342 11.72200012 Tm [(activat)1(es)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 283.52600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 288.02600098 11.72200012 Tm [(RA)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(C1.)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 13.46500015 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 17.96500015 27.3220005 Tm [(May)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 36.49700165 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 40.99700165 27.3220005 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 61.34400177 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 65.84400177 27.3220005 Tm [(relatively)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 104.4940033 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 108.9940033 27.3220005 Tm [(low)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 124.21700287 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 128.71699524 27.3220005 Tm [(activit)1(y)-1(.)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 161.35499573 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 165.85499573 27.3220005 Tm [(Plays)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 187.66099548 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 192.16099548 27.3220005 Tm [(a)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 197.13600159 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 201.63600159 27.3220005 Tm [(role)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 218.29600525 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 222.79600525 27.3220005 Tm [(in)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 230.73699951 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 235.23699951 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 249.23800659 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 253.73800659 27.3220005 Tm [(response)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 292.73498535 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 297.23498535 27.3220005 Tm [(t)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(o)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 5.72200012 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 10.22200012 42.92200089 Tm [(cl)-1(a)1(ss)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 30.43700027 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 34.93700027 42.92200089 Tm [(3)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 40.21500015 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 44.71500015 42.92200089 Tm [(semaph)1(orins)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 99.94999695 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 104.44999695 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 120.72699738 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 125.22699738 42.92200089 Tm [(remodeling)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 174.8809967 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 179.3809967 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 188.2230072 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 192.7230072 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 206.72399902 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 211.22399902 42.92200089 Tm [(actin)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 232.0059967 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 236.5059967 42.92200089 Tm [(cy)-1(t)1(oske)-1(leton.)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 293.31799316 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 297.81799316 42.92200089 Tm [(Pl)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ays)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 13.90400028 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 18.40399933 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 23.37899971 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 27.87899971 58.52199936 Tm [(role)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 44.53900146 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 49.03900146 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 56.97999954 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 61.47999954 58.52199936 Tm [(TNFS)-1(F11)-1(-)1(me)-1(d)1(i)-1(a)1(ted)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 144.04400635 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 148.54400635 58.52199936 Tm [(ost)1(e)-1(o)1(c)-1(last)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 192.01499939 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 196.51499939 58.52199936 Tm [(dif)1(fe)-1(r)1(e)-1(nt)1(i)-1(a)1(tion,)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 260.00698853 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 264.50698853 58.52199936 Tm [(espec)-1(iall)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(y)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 4.76399994 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 9.26399994 74.12200165 Tm [(in)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 17.20499992 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 21.70499992 74.12200165 Tm [(po)1(doso)1(me)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 68.08000183 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 72.58000183 74.12200165 Tm [(rearra)1(n)-1(g)1(e)-1(ment)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 136.79299927 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 141.29299927 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 157.57000732 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 162.07000732 74.12200165 Tm [(reorg)1(ani)-1(z)1(at)1(i)-1(o)1(n)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 224.85899353 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 229.35899353 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 238.20100403 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 242.70100403 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 256.70199585 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 261.20199585 74.12200165 Tm [(actin)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 281.98400879 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 286.48400879 74.12200165 Tm [(cy)-1(t)1(o)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ske)-1(leton.)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 38.46099854 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 42.96099854 89.72200012 Tm [(Regulat)1(e)-1(s)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 85.24099731 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 89.74099731 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 103.74199677 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 108.24199677 89.72200012 Tm [(activat)1(ion)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 150.19200134 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 154.69200134 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 163.53399658 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 168.03399658 89.72200012 Tm [(ITGB3)-1(,)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 195.6230011 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 200.1230011 89.72200012 Tm [(integrin)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 233.65800476 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 238.15800476 89.72200012 Tm [(signaling)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 277.08898926 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 281.58898926 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 297.86599731 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 14.40999985 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 18.90999985 105.3219986 Tm [(ad)1(hesion)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 58.11800003 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 62.61800003 105.3219986 Tm [(\(By)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 76.03500366 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 80.53500366 105.3219986 Tm [(similarit)1(y)-1(\).)] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 124.41400146 105.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.05000305 0.75 m 113.05000305 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.05000305 17.10000038 m 113.05000305 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.05000305 33.45000076 m 113.05000305 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.05000305 49.80000305 m 113.05000305 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.05000305 66.15000153 m 113.05000305 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.05000305 82.5 m 113.05000305 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.05000305 98.84999847 m 113.05000305 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.05000305 115.19999695 m 113.05000305 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.54998779 0.75 m 426.54998779 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17498779 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 426.17498779 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 224.7749939 m 426.92498779 224.7749939 l S Q Q q 1 0 0 1 0 608.2789917 cm Q Q 1 0 0 -1 0 841.90002441 cm 
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