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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 98.01699829 23.67700005 Tm 0 g [(HK3)] TJ ET EMC /P <</Lang (zh-CN) /MCID 1 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 140.57800293 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 317.28201294 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 3 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 4 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(HK3)] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 72.44400024 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 156.44400024 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(HK3)] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 80.31900024 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 82.69300079 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 115.89499664 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 118.26899719 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 178.24899292 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 180.6230011 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 215.09700012 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 17 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 18 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 19 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 20 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(HXK3)1(;)] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 88.57800293 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 90.95200348 12.82499981 Tm [(HKII)1(I)] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 110.88600159 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 25 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <</MCID 26 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 27 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <</MCID 28 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 29 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <</MCID 30 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 31 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <</MCID 32 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 33 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <</MCID 34 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 35 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001B000F>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 242.43400574 cm /P <</MCID 42 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -0.64999998 270.37298584 cm q -0.75 -0.5 m 422.1000061 -0.5 l 422.1000061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 43 >> BDC q /GS2 gs 1 g 0 1.25 m 28.15600014 1.25 l 28.15600014 16.68799973 l 0 16.68799973 l h f* Q q /GS2 gs 1 g 28.15600014 1.25 m 30.81900024 1.25 l 30.81900024 16.68799973 l 28.15600014 16.68799973 l h f* Q q /GS2 gs 1 g 30.81900024 1.25 m 62.12599945 1.25 l 62.12599945 16.68799973 l 30.81900024 16.68799973 l h f* Q q /GS2 gs 1 g 62.12599945 1.25 m 64.78900146 1.25 l 64.78900146 16.68799973 l 62.12599945 16.68799973 l h f* Q q /GS2 gs 1 g 64.78900146 1.25 m 127.63999939 1.25 l 127.63999939 16.68799973 l 64.78900146 16.68799973 l h f* Q q /GS2 gs 1 g 127.63999939 1.25 m 130.30299377 1.25 l 130.30299377 16.68799973 l 127.63999939 16.68799973 l h f* Q q /GS2 gs 1 g 130.30299377 1.25 m 139.37799072 1.25 l 139.37799072 16.68799973 l 130.30299377 16.68799973 l h f* Q q /GS2 gs 1 g 139.37800598 1.25 m 142.04100037 1.25 l 142.04100037 16.68799973 l 139.37800598 16.68799973 l h f* Q q /GS2 gs 1 g 142.04100037 1.25 m 147.01600647 1.25 l 147.01600647 16.68799973 l 142.04100037 16.68799973 l h f* Q q /GS2 gs 1 g 147.01600647 1.25 m 149.67900085 1.25 l 149.67900085 16.68799973 l 147.01600647 16.68799973 l h f* Q q /GS2 gs 1 g 149.67900085 1.25 m 177.64100647 1.25 l 177.64100647 16.68799973 l 149.67900085 16.68799973 l h f* Q q /GS2 gs 1 g 177.64100647 1.25 m 180.30400085 1.25 l 180.30400085 16.68799973 l 177.64100647 16.68799973 l h f* Q q /GS2 gs 1 g 180.30400085 1.25 m 212.58599854 1.25 l 212.58599854 16.68799973 l 180.30400085 16.68799973 l h f* Q q /GS2 gs 1 g 212.58599854 1.25 m 215.24899292 1.25 l 215.24899292 16.68799973 l 212.58599854 16.68799973 l h f* Q q /GS2 gs 1 g 215.24899292 1.25 m 235.95999146 1.25 l 235.95999146 16.68799973 l 215.24899292 16.68799973 l h f* Q q /GS2 gs 1 g 235.96000671 1.25 m 238.6230011 1.25 l 238.6230011 16.68799973 l 235.96000671 16.68799973 l h f* Q q /GS2 gs 1 g 238.6230011 1.25 m 274.18399048 1.25 l 274.18399048 16.68799973 l 238.6230011 16.68799973 l h f* Q q /GS2 gs 1 g 274.18399048 1.25 m 276.84698486 1.25 l 276.84698486 16.68799973 l 274.18399048 16.68799973 l h f* Q q /GS2 gs 1 g 276.84698486 1.25 m 303.91699219 1.25 l 303.91699219 16.68799973 l 276.84698486 16.68799973 l h f* Q q /GS2 gs 1 g 303.91699219 1.25 m 306.57998657 1.25 l 306.57998657 16.68799973 l 303.91699219 16.68799973 l h f* Q q /GS2 gs 1 g 306.57998657 1.25 m 328.38598633 1.25 l 328.38598633 16.68799973 l 306.57998657 16.68799973 l h f* Q q /GS2 gs 1 g 328.38598633 1.25 m 331.04898071 1.25 l 331.04898071 16.68799973 l 328.38598633 16.68799973 l h f* Q q /GS2 gs 1 g 331.04901123 1.25 m 339.89102173 1.25 l 339.89102173 16.68799973 l 331.04901123 16.68799973 l h f* Q q /GS2 gs 1 g 339.89099121 1.25 m 342.5539856 1.25 l 342.5539856 16.68799973 l 339.89099121 16.68799973 l h f* Q q /GS2 gs 1 g 342.5539856 1.25 m 372.5949707 1.25 l 372.5949707 16.68799973 l 342.5539856 16.68799973 l h f* Q q /GS2 gs 1 g 372.59500122 1.25 m 375.25799561 1.25 l 375.25799561 16.68799973 l 372.59500122 16.68799973 l h f* Q q /GS2 gs 1 g 375.25799561 1.25 m 393.20999146 1.25 l 393.20999146 16.68799973 l 375.25799561 16.68799973 l h f* Q EMC /P <</MCID 44 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 12.89099979 Tm /GS2 gs 0.13333334 g [(Fusion)] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 28.15600014 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 30.81900024 12.89099979 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 62.12599945 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 64.78900146 12.89099979 Tm [(correspond)1(i)-1(ng)] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 127.63999939 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 130.30299377 12.89099979 Tm [(to)] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 139.37800598 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 142.04100037 12.89099979 Tm [(a)] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 147.01600647 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 149.67900085 12.89099979 Tm [(region)] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 177.64100647 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 180.30400085 12.89099979 Tm [(derived)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 212.58599854 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 215.24899292 12.89099979 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 235.96000671 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 238.6230011 12.89099979 Tm [(26)-1(8-51)-1(5)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 274.18399048 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 276.84698486 12.89099979 Tm [(amino)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 303.91699219 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 306.57998657 12.89099979 Tm [(acids)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 328.38598633 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 331.04901123 12.89099979 Tm [(of)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 339.89099121 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 342.5539856 12.89099979 Tm [(human)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 372.59500122 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 375.25799561 12.89099979 Tm [(HK3)] TJ ET EMC /P <</MCID 71 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 393.20999146 12.89099979 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 421.3500061 0.5 m 421.3500061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 421.6000061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 421.6000061 28.68899918 l S Q Q q 1 0 0 1 0 299.31201172 cm /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 327.25100708 cm /P <</Lang (zh-CN) /MCID 73 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F000F>] TJ ET EMC /P <</MCID 74 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 355.19000244 cm /P <</MCID 75 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 383.1289978 cm q /GS2 gs 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 149.0249939 -0.25 l 149.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 76 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 79 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 148.7749939 0.75 m 426.125 0.75 l 426.125 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm -0.625 -0.25 m 278.7250061 -0.25 l 278.7250061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 80 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(hexokinase)] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 48.01900101 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 52.51900101 11.72200012 Tm [(3)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 57.79700089 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 62.29700089 11.72200012 Tm [(\(wh)1(ite)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 88.80500031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 93.30500031 11.72200012 Tm [(ce)-1(ll\))] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 110.72100067 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 149.0249939 -0.25 l 149.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 88 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 148.7749939 0.75 m 426.125 0.75 l 426.125 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm -0.625 -0.25 m 278.7250061 -0.25 l 278.7250061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 90 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(HXK3)-1(;)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 25.92300034 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 30.42300034 11.72200012 Tm [(HKIII)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 51.03300095 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 149.0249939 -0.25 l 149.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 94 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 95 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 148.7749939 0.75 m 426.125 0.75 l 426.125 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm -0.625 -0.25 m 278.7250061 -0.25 l 278.7250061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 96 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(P52)-1(79)-1(0)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 31.89599991 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 149.0249939 -0.25 l 149.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 98 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 101 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 148.7749939 0.75 m 426.125 0.75 l 426.125 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm -0.625 -0.25 m 278.7250061 -0.25 l 278.7250061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 102 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(28)-1(12)-1(9)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 149.0249939 -0.25 l 149.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 104 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 105 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 148.7749939 0.75 m 426.125 0.75 l 426.125 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm -0.625 -0.25 m 278.7250061 -0.25 l 278.7250061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 106 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 149.0249939 -0.25 l 149.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 122 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 125 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 148.7749939 0.75 m 426.125 0.75 l 426.125 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm -0.625 -0.25 m 278.7250061 -0.25 l 278.7250061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 126 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 149.0249939 -0.25 l 149.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 130 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 131 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 148.7749939 0.75 m 426.125 0.75 l 426.125 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm -0.625 -0.25 m 278.7250061 -0.25 l 278.7250061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 132 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 78.75 l 0.375 78.75 l h f* Q q -0.625 -0.25 m 149.0249939 -0.25 l 149.0249939 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 144 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 42.92200089 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 145 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 57.29199982 42.92200089 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 148.7749939 0.75 m 426.125 0.75 l 426.125 78.75 l 148.7749939 78.75 l h f* Q q 1 0 0 1 148.3999939 0 cm -0.625 -0.25 m 278.7250061 -0.25 l 278.7250061 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 146 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(He)-1(xo)1(k)-1(inases)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 53.60400009 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 58.10400009 11.72200012 Tm [(ph)1(osph)1(orylate)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 120.3219986 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 124.8219986 11.72200012 Tm [(glucose)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 158.0269928 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 162.5269928 11.72200012 Tm [(to)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 171.602005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 176.102005 11.72200012 Tm [(pro)1(duc)-1(e)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 211.93099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 216.43099976 11.72200012 Tm [(glucose-6-p)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ho)1(spha)1(te,)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 42.31900024 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 46.81900024 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 60.81999969 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 65.31999969 27.3220005 Tm [(first)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 81.79100037 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 86.29100037 27.3220005 Tm [(st)1(e)-1(p)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 104.66500092 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 109.16500092 27.3220005 Tm [(in)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 117.10600281 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 121.60600281 27.3220005 Tm [(most)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 143.27999878 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 147.77999878 27.3220005 Tm [(glucose)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 180.98500061 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 185.48500061 27.3220005 Tm [(metab)1(olism)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 236.21099854 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 240.71099854 27.3220005 Tm [(pa)1(thw)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ays.)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 16.07099915 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 20.57099915 42.92200089 Tm [(This)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 37.83300018 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 42.33300018 42.92200089 Tm [(gene)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 63.84899902 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 68.34899902 42.92200089 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 104.26599884 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 108.76599884 42.92200089 Tm [(hexokinase)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 156.78500366 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 161.28500366 42.92200089 Tm [(3.)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 168.72900391 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 173.22900391 42.92200089 Tm [(Simil)-1(a)1(r)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 202.45300293 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 206.95300293 42.92200089 Tm [(to)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 216.02799988 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 220.52799988 42.92200089 Tm [(hexokinase)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(s)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 4.16599989 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 8.66600037 58.52199936 Tm [(1)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 13.94400024 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 18.44400024 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 34.72100067 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 39.22100067 58.52199936 Tm [(2,)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 46.66500092 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 51.16500092 58.52199936 Tm [(th)1(is)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 66.6210022 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 71.1210022 58.52199936 Tm [(allost)1(e)-1(r)1(ic)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 109.57800293 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 114.07800293 58.52199936 Tm [(en)-1(z)1(y)-1(me)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 147.45899963 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 151.95899963 58.52199936 Tm [(is)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 158.52000427 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 163.02000427 58.52199936 Tm [(inhibited)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 201.25700378 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 205.75700378 58.52199936 Tm [(by)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 216.26899719 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 220.76899719 58.52199936 Tm [(its)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 230.68299866 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 235.18299866 58.52199936 Tm [(pro)1(duc)-1(t)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 269.25799561 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(glucose-6-pho)1(spha)1(te.)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 94.33699799 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 193.19999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 0.75 m 148.3999939 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 17.10000038 m 148.3999939 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 33.45000076 m 148.3999939 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 49.80000305 m 148.3999939 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 66.15000153 m 148.3999939 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 82.5 m 148.3999939 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 98.84999847 m 148.3999939 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 115.19999695 m 148.3999939 193.19999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.5 0.75 m 426.5 193.19999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.875 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.125 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.125 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.125 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.125 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.125 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.125 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 426.125 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 193.57499695 m 426.875 193.57499695 l S Q Q q 1 0 0 1 0 577.07897949 cm Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
endobj
6 0 obj
<</Length1 98 0 R/Length 24544>>stream
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