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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 85.29299927 23.67700005 Tm 0 g [(NR4A)1(2)] TJ ET EMC /P <> BDC BT /FAAABE 22 Tf 1 0 0 -1 153.30200195 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 330.00601196 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm [(NR)1(4A2)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 94.82299805 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 178.82299805 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(NR)1(4A2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.19799805 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.5719986 12.82499981 Tm [(Antigen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.77400208 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.147995 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.12800598 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.5019989 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.97599792 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(NOT;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.65599823 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.02999878 12.82499981 Tm [(RN)1(R1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.34200287 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.71600342 12.82499981 Tm [(HZF)-1(-3;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.34500122 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.71899414 12.82499981 Tm [(NU)1(RR1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.76699829 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.14100647 12.82499981 Tm [(TINU)1(R)] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.1190033 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 21 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 242.43400574 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 270.37298584 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 47.37799835 l -0.75 47.37799835 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.9109993 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.85000038 12.55799961 Tm [(protein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.23199844 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.17099762 12.55799961 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.7559967 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.69500732 12.55799961 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.74899292 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.68800354 12.55799961 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.71800232 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.65699768 12.55799961 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.94799805 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.88699341 12.55799961 Tm [(derive)1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.18200684 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.1210022 12.55799961 Tm [(from)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.91099548 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.8500061 12.55799961 Tm [(C)] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.44900513 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.38800049 12.55799961 Tm [(ter)1(min)-1(al)] TJ ET EMC /P <> BDC BT 1 0 0 -1 292.54299927 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 296.48199463 12.55799961 Tm [(300)] TJ ET EMC /P <> BDC BT 1 0 0 -1 312.44699097 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 316.38598633 12.55799961 Tm [(amin)-1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 343.26699829 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 347.20599365 12.55799961 Tm [(acid)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 368.70800781 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 372.64700317 12.55799961 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 381.38800049 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 385.32699585 12.55799961 Tm [(hu)-1(man)] TJ ET EMC /P <> BDC BT 1 0 0 -1 415.29400635 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 30.49699783 Tm [(NR)1(4A2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.19799995 30.49699783 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 46.37799835 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 46.37799835 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 46.62799835 m 426.3500061 46.62799835 l S Q Q q 1 0 0 1 0 317.25100708 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 345.19000244 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 373.1289978 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 401.06799316 cm q /GS2 gs 1 g 0.375 0.75 m 111.67500305 0.75 l 111.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 112.67500305 -0.25 l 112.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 112.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 112.42500305 16.35000038 l h f* Q q 1 0 0 1 112.05000305 0 cm -0.625 -0.25 m 315.125 -0.25 l 315.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(nuc)-1(lear)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.51799965 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.01800156 11.72200012 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.44000244 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.94000244 11.72200012 Tm [(subf)1(amily)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.48200226 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.98200226 11.72200012 Tm [(4,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.42599487 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.92599487 11.72200012 Tm [(gr)1(oup)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.13499451 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.63499451 11.72200012 Tm [(A,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.13400269 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.63400269 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.897995 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.397995 11.72200012 Tm [(2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.67599487 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 111.67500305 0.75 l 111.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 112.67500305 -0.25 l 112.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 112.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 112.42500305 16.35000038 l h f* Q q 1 0 0 1 112.05000305 0 cm -0.625 -0.25 m 315.125 -0.25 l 315.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(NOT;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.97699928 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.47699928 11.72200012 Tm [(RNR1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.98899841 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.48899841 11.72200012 Tm [(HZ)-1(F-)1(3)-1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.15000153 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.65000153 11.72200012 Tm [(NUR)1(R1)-1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.8809967 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.3809967 11.72200012 Tm [(TINUR)] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.09700012 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 111.67500305 0.75 l 111.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 112.67500305 -0.25 l 112.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 112.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 112.42500305 16.35000038 l h f* Q q 1 0 0 1 112.05000305 0 cm -0.625 -0.25 m 315.125 -0.25 l 315.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(P43)-1(35)-1(4)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.89599991 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 111.67500305 0.75 l 111.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 112.67500305 -0.25 l 112.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 112.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 112.42500305 16.35000038 l h f* Q q 1 0 0 1 112.05000305 0 cm -0.625 -0.25 m 315.125 -0.25 l 315.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(09)-1(28)-1(8)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 111.67500305 0.75 l 111.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 112.67500305 -0.25 l 112.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 112.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 112.42500305 16.35000038 l h f* Q q 1 0 0 1 112.05000305 0 cm -0.625 -0.25 m 315.125 -0.25 l 315.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 111.67500305 0.75 l 111.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 112.67500305 -0.25 l 112.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 112.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 112.42500305 16.35000038 l h f* Q q 1 0 0 1 112.05000305 0 cm -0.625 -0.25 m 315.125 -0.25 l 315.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 111.67500305 0.75 l 111.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 112.67500305 -0.25 l 112.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 112.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 112.42500305 16.35000038 l h f* Q q 1 0 0 1 112.05000305 0 cm -0.625 -0.25 m 315.125 -0.25 l 315.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 111.67500305 0.75 l 111.67500305 94.34999847 l 0.375 94.34999847 l h f* Q q -0.625 -0.25 m 112.67500305 -0.25 l 112.67500305 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 50.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 50.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 112.42500305 0.75 m 426.17498779 0.75 l 426.17498779 94.34999847 l 112.42500305 94.34999847 l h f* Q q 1 0 0 1 112.05000305 0 cm -0.625 -0.25 m 315.125 -0.25 l 315.125 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(st)1(e)-1(ro)1(i)-1(d)1(-t)1(hyroid)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.07400513 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.57400513 11.72200012 Tm [(ho)1(rmone)-1(-)1(retin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(oid)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.8739996 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.37400055 27.3220005 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.79600143 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.29600143 27.3220005 Tm [(superfa)1(mi)-1(ly.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.54699707 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.04699707 27.3220005 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.85400391 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.35400391 27.3220005 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.86099243 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.36099243 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.66799927 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.16799927 27.3220005 Tm [(may)] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.33900452 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.83900452 27.3220005 Tm [(act)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.67999268 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.17999268 27.3220005 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 263.3210144 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.8210144 27.3220005 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 272.79598999 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 277.29598999 27.3220005 Tm [(tr)1(ansc)-1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ipt)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.1590004 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.6590004 42.92200089 Tm [(fa)1(c)-1(t)1(or.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.94499969 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.44499969 42.92200089 Tm [(Mutat)1(ions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.29399872 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.79399872 42.92200089 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.73500061 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.23500061 42.92200089 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.69099426 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.19099426 42.92200089 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.70700073 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.20700073 42.92200089 Tm [(ha)1(ve)] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.55400085 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.05400085 42.92200089 Tm [(been)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.56100464 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.06100464 42.92200089 Tm [(asso)1(c)-1(iat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.18798828 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 268.68798828 42.92200089 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 287.08401489 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 291.58401489 42.92200089 Tm [(dis)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ord)1(e)-1(r)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.62400055 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.12400055 58.52199936 Tm [(related)] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.25299835 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.75299835 58.52199936 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.82800293 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.32800293 58.52199936 Tm [(do)1(pamine)-1(r)1(gic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.11099243 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.61099243 58.52199936 Tm [(dysfunction,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.20500183 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.70500183 58.52199936 Tm [(inc)-1(luding)] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.55499268 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.05499268 58.52199936 Tm [(Par)1(k)-1(inson)] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.24700928 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 292.74700928 58.52199936 Tm [(dis)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ease,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.52000046 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.02000046 74.12200165 Tm [(schizop)1(herni)-1(a)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.6969986 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.1969986 74.12200165 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.47399902 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.97399902 74.12200165 Tm [(manic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.83599854 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.33599854 74.12200165 Tm [(depression.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.65100098 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.15100098 74.12200165 Tm [(Misregulatio)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.73599243 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.23599243 74.12200165 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.07800293 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 274.57800293 74.12200165 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 290.03399658 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 294.53399658 74.12200165 Tm [(ge)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ne)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.65200043 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.15200043 89.72200012 Tm [(may)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.32300186 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.82300186 89.72200012 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.67699814 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.17699814 89.72200012 Tm [(asso)1(c)-1(iat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.30400085 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.80400085 89.72200012 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.19999695 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.69999695 89.72200012 Tm [(rheumat)1(oid)] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.96499634 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.46499634 89.72200012 Tm [(art)1(hrit)1(is.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.68299866 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.18299866 89.72200012 Tm [(Alt)1(e)-1(rna)1(tivel)-1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 274.06399536 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.56399536 89.72200012 Tm [(splice)] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 208.79998779 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 112.05000305 0.75 m 112.05000305 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 112.05000305 17.10000038 m 112.05000305 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 112.05000305 33.45000076 m 112.05000305 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 112.05000305 49.80000305 m 112.05000305 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 112.05000305 66.15000153 m 112.05000305 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 112.05000305 82.5 m 112.05000305 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 112.05000305 98.84999847 m 112.05000305 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 112.05000305 115.19999695 m 112.05000305 208.79998779 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.54998779 0.75 m 426.54998779 208.79998779 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17498779 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 426.17498779 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 209.17498779 m 426.92498779 209.17498779 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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