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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 269.45001221 0 0 -90.09999847 0 90.09999847 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</Lang (zh-CN) /MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 102.72899628 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>] TJ ET EMC /P <</MCID 1 >> BDC BT /FAAABG 22 Tf 1 0 0 -1 152.40499878 23.67700005 Tm 0 Tr [(AHI)1(1)] TJ ET EMC /P <</Lang (zh-CN) /MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 202.1309967 23.67700005 Tm 2 Tr [<0005>-4<0006>-4<0007>-4<0004>-4<0008>] TJ ET EMC /P <</MCID 3 >> BDC BT /FAAABG 22 Tf 1 0 0 -1 312.5710144 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 4 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 76.125 12.82499981 Tm [(AHI1)] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 99.33499908 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 151.83500671 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 157.08500671 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(A)1(HI1)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 104.31800079 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 106.69200134 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 132.34199524 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 134.71600342 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 178.2749939 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 180.64900208 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 218.44500732 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ORF)-1(1)1(;)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 88.60900116 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 90.98300171 12.82499981 Tm [(AHI-1;)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 117.59200287 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 119.96600342 12.82499981 Tm [(JBTS)-1(3)1(;)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 147.0980072 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 149.47200012 12.82499981 Tm [(dJ71N)1(10.)-1(1)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 194.37399292 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 32 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 33 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 34 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 35 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 37 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <</MCID 38 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 39 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0015000D>] TJ ET EMC /P <</MCID 40 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 41 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <</MCID 42 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001B>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001C000D>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001D000D>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(AHI1)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 83.58499908 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002200230024000D>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700120025000D>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 73 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 74 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 75 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 159.2749939 0.75 l 159.2749939 109.94999695 l 0.375 109.94999695 l h f* Q q -0.625 -0.25 m 160.2749939 -0.25 l 160.2749939 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 77 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 58.52199936 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 58.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 160.0249939 0.75 m 422.42498779 0.75 l 422.42498779 109.94999695 l 160.0249939 109.94999695 l h f* Q q 1 0 0 1 159.6499939 0 cm -0.625 -0.25 m 263.7749939 -0.25 l 263.7749939 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 79 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 54.3390007 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 58.8390007 11.72200012 Tm [(ap)1(parently)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 104.88500214 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 109.38500214 11.72200012 Tm [(required)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 145.92599487 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 150.42599487 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 162.70399475 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 167.20399475 11.72200012 Tm [(bo)1(th)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 187.56799316 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 192.06799316 11.72200012 Tm [(ce)-1(rebellar)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 234.28599548 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 238.78599548 11.72200012 Tm [(and)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 255.06300354 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(cortical)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 31.30200005 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 35.80199814 27.3220005 Tm [(development)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 92.7990036 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 97.2990036 27.3220005 Tm [(in)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 105.23999786 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 109.73999786 27.3220005 Tm [(humans.)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 146.11399841 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 150.61399841 27.3220005 Tm [(This)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 167.87600708 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 172.37600708 27.3220005 Tm [(gene)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 193.89199829 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 198.39199829 27.3220005 Tm [(mutat)1(ions)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 241.88000488 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 246.38000488 27.3220005 Tm [(c)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ause)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 19.79299927 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 24.29299927 42.92200089 Tm [(speci)-1(f)1(ic)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 56.25 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 60.75 42.92200089 Tm [(fo)1(rms)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 85.6269989 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 90.1269989 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 98.96900177 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 103.46900177 42.92200089 Tm [(Joubert)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 135.94500732 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 140.44500732 42.92200089 Tm [(syndrome-r)1(e)-1(lat)1(e)-1(d)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 217.397995 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 221.897995 42.92200089 Tm [(diso)1(rde)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(rs.)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 9.76900005 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 14.26900005 58.52199936 Tm [(Joubert)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 46.74499893 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 51.24499893 58.52199936 Tm [(syndrome)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 94.17500305 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 98.67500305 58.52199936 Tm [(\(JS\))] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 113.44499969 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 117.94499969 58.52199936 Tm [(is)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 124.5059967 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 129.0059967 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 133.98100281 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 138.48100281 58.52199936 Tm [(rec)-1(essively)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 184.36000061 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 188.86000061 58.52199936 Tm [(inherited)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 227.49699402 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 231.99699402 58.52199936 Tm [(devel)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(op)1(me)-1(nta)1(l)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 41.27799988 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 45.77799988 74.12200165 Tm [(bra)1(in)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 67.87799835 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 72.37799835 74.12200165 Tm [(diso)1(rder)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 108.15399933 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 112.65399933 74.12200165 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 131.05000305 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 135.55000305 74.12200165 Tm [(seve)-1(r)1(al)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 165.45899963 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 169.95899963 74.12200165 Tm [(identified)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 210.88999939 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 215.38999939 74.12200165 Tm [(causative)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 255.14300537 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(chromos)1(omal)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 59.05799866 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 63.55799866 89.72200012 Tm [(loci.)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 80.74900055 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 85.24900055 89.72200012 Tm [(Alt)1(e)-1(rna)1(tivel)-1(y)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 139.13000488 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 143.63000488 89.72200012 Tm [(splice)-1(d)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 173.71099854 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 178.21099854 89.72200012 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 219.13299561 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 223.63299561 89.72200012 Tm [(var)1(i)-1(a)1(n)-1(t)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(s)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 4.16599989 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 8.66600037 105.3219986 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 49.00799942 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 53.50799942 105.3219986 Tm [(dif)1(fe)-1(r)1(e)-1(nt)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 90.44799805 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 94.94799805 105.3219986 Tm [(isof)1(orms)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 132.10800171 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 136.60800171 105.3219986 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 156.95500183 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 161.45500183 105.3219986 Tm [(been)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 182.96200562 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 187.46200562 105.3219986 Tm [(identified.)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 230.55900574 105.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 109.94999695 cm q /GS2 gs 1 g 0.375 0.75 m 159.2749939 0.75 l 159.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 160.2749939 -0.25 l 160.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 181 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 182 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 160.0249939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 160.0249939 16.35000038 l h f* Q q 1 0 0 1 159.6499939 0 cm -0.625 -0.25 m 263.7749939 -0.25 l 263.7749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 183 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ELISA,)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 25.90600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 30.40600014 11.72200012 Tm [(IHC)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 46.03300095 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 126.30000305 cm q /GS2 gs 1 g 0.375 0.75 m 159.2749939 0.75 l 159.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 160.2749939 -0.25 l 160.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 187 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 192 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 160.0249939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 160.0249939 16.35000038 l h f* Q q 1 0 0 1 159.6499939 0 cm -0.625 -0.25 m 263.7749939 -0.25 l 263.7749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 193 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(AHI1)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 21.21699905 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 142.6499939 cm q /GS2 gs 1 g 0.375 0.75 m 159.2749939 0.75 l 159.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 160.2749939 -0.25 l 160.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 195 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 196 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 160.0249939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 160.0249939 16.35000038 l h f* Q q 1 0 0 1 159.6499939 0 cm -0.625 -0.25 m 263.7749939 -0.25 l 263.7749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 197 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Syn)-1(t)1(hetic)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 39.76599884 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 44.26599884 11.72200012 Tm [(pept)1(ide)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 77.48000336 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 81.98000336 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 90.8219986 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 95.3219986 11.72200012 Tm [(humanAHI1)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 146.58000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 159 cm q /GS2 gs 1 g 0.375 0.75 m 159.2749939 0.75 l 159.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 160.2749939 -0.25 l 160.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 205 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 208 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 160.0249939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 160.0249939 16.35000038 l h f* Q q 1 0 0 1 159.6499939 0 cm -0.625 -0.25 m 263.7749939 -0.25 l 263.7749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 209 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Ab)1(e)-1(lso)1(n)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 35.01599884 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 39.51599884 11.72200012 Tm [(helper)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 66.84999847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 71.34999847 11.72200012 Tm [(integra)1(tion)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 118.93399811 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 123.43399811 11.72200012 Tm [(site)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 138.45500183 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 142.95500183 11.72200012 Tm [(1)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 148.23300171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 175.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 159.6499939 0.75 m 159.6499939 109.94999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 159.6499939 110.69999695 m 159.6499939 126.29999542 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 159.6499939 127.04999542 m 159.6499939 142.6499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 159.6499939 143.3999939 m 159.6499939 159 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 159.6499939 159.75 m 159.6499939 175.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 175.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 110.32499695 m 422.42498779 110.32499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 126.67499542 m 422.42498779 126.67499542 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 143.0249939 m 422.42498779 143.0249939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 159.375 m 422.42498779 159.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 175.7250061 m 423.17498779 175.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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