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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 269.45001221 0 0 -90.09999847 0 90.09999847 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</Lang (zh-CN) /MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 93.44200134 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>] TJ ET EMC /P <</MCID 1 >> BDC BT /FAAABG 22 Tf 1 0 0 -1 143.11799622 23.67700005 Tm 0 Tr [(CFL1/2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 211.41700745 23.67700005 Tm 2 Tr [<0005>-4<0006>-4<0007>-4<0004>-4<0008>] TJ ET EMC /P <</MCID 3 >> BDC BT /FAAABG 22 Tf 1 0 0 -1 321.85699463 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 4 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 76.125 12.82499981 Tm [(CF)-1(L1/2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.28600311 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 160.78599548 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 171.28599548 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CFL)-1(1/2)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 113.26999664 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 115.64399719 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 141.29400635 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 143.66799927 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 187.227005 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 189.60099792 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 227.39700317 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CF)-1(L;)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 80.64700317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 83.02100372 12.82499981 Tm [(HEL)-1(-S-)-1(1)1(5/NEM7)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 151.26100159 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 28 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 29 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 30 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0010000D>] TJ ET EMC /P <</MCID 31 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CF)-1(L1/2)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 92.53600311 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 34 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 35 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0012000D>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001300140015>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<00160017>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<00180019>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001B000D>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F000D>] TJ ET EMC /P <</MCID 52 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 96.36599731 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 125.72799683 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 128.102005 12.82499981 Tm [(Rat)] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 142.3500061 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 59 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002000210022000F000D>] TJ ET EMC /P <</MCID 60 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 61 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00230004>] TJ ET EMC /P <</MCID 62 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 64 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002400250026000D>] TJ ET EMC /P <</MCID 65 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 69 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700220027000D>] TJ ET EMC /P <</MCID 70 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 73 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 74 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 75 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 142.0249939 0.75 l 142.0249939 125.55000305 l 0.375 125.55000305 l h f* Q q -0.625 -0.25 m 143.0249939 -0.25 l 143.0249939 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 77 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 66.3219986 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 66.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 142.7749939 0.75 m 422.42498779 0.75 l 422.42498779 125.55000305 l 142.7749939 125.55000305 l h f* Q q 1 0 0 1 142.3999939 0 cm -0.625 -0.25 m 281.0249939 -0.25 l 281.0249939 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 79 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Bi)-1(nd)1(s)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 23.51099968 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 28.01099968 11.72200012 Tm [(to)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 37.08599854 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 41.58599854 11.72200012 Tm [(F-actin)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 71.04299927 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 75.54299927 11.72200012 Tm [(and)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 91.81999969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 96.31999969 11.72200012 Tm [(exhibit)1(s)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 129.58700562 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 134.08700562 11.72200012 Tm [(pH-sensitive)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 187.647995 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 192.147995 11.72200012 Tm [(F-actin)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 221.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 226.10499573 11.72200012 Tm [(depo)1(l)-1(ymer)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(izing)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 20.51799965 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 25.01799965 27.3220005 Tm [(activit)1(y)-1(.)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 57.65599823 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 62.15599823 27.3220005 Tm [(Regulat)1(e)-1(s)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 104.43599701 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 108.93599701 27.3220005 Tm [(actin)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 129.71800232 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 134.21800232 27.3220005 Tm [(cy)-1(t)1(oske)-1(leton)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 188.86399841 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 193.36399841 27.3220005 Tm [(dynamics.)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 236.07899475 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 240.57899475 27.3220005 Tm [(Impo)1(rt)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ant)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 13.8739996 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 18.37400055 42.92200089 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 30.65200043 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 35.15200043 42.92200089 Tm [(normal)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 65.65899658 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 70.15899658 42.92200089 Tm [(pro)1(gress)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 107.6969986 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 112.1969986 42.92200089 Tm [(th)1(rough)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 147.09399414 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 151.59399414 42.92200089 Tm [(mito)1(sis)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 182.22399902 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 186.72399902 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 203.00100708 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 207.50100708 42.92200089 Tm [(normal)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 238.00799561 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 242.50799561 42.92200089 Tm [(cy)-1(t)1(oki)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ne)-1(s)1(i)-1(s)1(.)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 23.54599953 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 28.04599953 58.52199936 Tm [(Plays)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 49.85200119 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 54.35200119 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 59.32699966 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 63.82699966 58.52199936 Tm [(role)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 80.48699951 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 84.98699951 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 92.9280014 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 97.4280014 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 111.42900085 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 115.92900085 58.52199936 Tm [(regulat)1(i)-1(o)1(n)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 160.16000366 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 164.66000366 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 173.5019989 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 178.0019989 58.52199936 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 192.41200256 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 196.91200256 58.52199936 Tm [(morp)1(holog)1(y)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 250.1519928 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 254.6519928 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 270.9289856 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(cy)-1(t)1(oske)-1(letal)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 50.7480011 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 55.2480011 74.12200165 Tm [(org)1(anizat)1(ion.)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 111.66100311 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 116.16100311 74.12200165 Tm [(Required)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 155.13999939 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 159.63999939 74.12200165 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 171.91799927 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 176.41799927 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 190.41900635 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 194.91900635 74.12200165 Tm [(up-)1(re)-1(g)1(u)-1(la)1(tion)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 254.33700562 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 258.83700562 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 267.6789856 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(at)1(y)-1(p)1(ic)-1(al)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 33.11700058 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 37.61700058 89.72200012 Tm [(che)-1(mo)1(k)-1(ine)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 84.87999725 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 89.37999725 89.72200012 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 125.80200195 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 130.30200195 89.72200012 Tm [(ACK)1(R2)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 159.52099609 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 164.02099609 89.72200012 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 184.73199463 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 189.23199463 89.72200012 Tm [(en)-1(d)1(osoma)1(l)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 237.05299377 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 241.55299377 89.72200012 Tm [(compa)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(rt)1(me)-1(nt)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 29.22800064 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 33.72800064 105.3219986 Tm [(to)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 42.8030014 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 47.3030014 105.3219986 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 61.71300125 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 66.21299744 105.3219986 Tm [(membrane,)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 115.16400146 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 119.66400146 105.3219986 Tm [(inc)-1(reasing)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 163.49899292 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 167.99899292 105.3219986 Tm [(its)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 177.91299438 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 182.41299438 105.3219986 Tm [(efficie)-1(ncy)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 222.99200439 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 227.49200439 105.3219986 Tm [(in)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 235.43299866 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 239.93299866 105.3219986 Tm [(che)-1(mo)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(ki)-1(ne)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 17.9470005 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 22.4470005 120.92199707 Tm [(upt)1(ak)-1(e)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 52.07500076 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 56.57500076 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 72.85199738 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 77.35199738 120.92199707 Tm [(degra)1(dat)1(ion.)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 132.29699707 120.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 125.55000305 cm q /GS2 gs 1 g 0.375 0.75 m 142.0249939 0.75 l 142.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 143.0249939 -0.25 l 143.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 198 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 199 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 142.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 142.7749939 16.35000038 l h f* Q q 1 0 0 1 142.3999939 0 cm -0.625 -0.25 m 281.0249939 -0.25 l 281.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 200 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 14.80500031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 141.8999939 cm q /GS2 gs 1 g 0.375 0.75 m 142.0249939 0.75 l 142.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 143.0249939 -0.25 l 143.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 202 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 207 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 142.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 142.7749939 16.35000038 l h f* Q q 1 0 0 1 142.3999939 0 cm -0.625 -0.25 m 281.0249939 -0.25 l 281.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 208 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CFL1)-1(/2)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 29.82099915 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 158.25 cm q /GS2 gs 1 g 0.375 0.75 m 142.0249939 0.75 l 142.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 143.0249939 -0.25 l 143.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 210 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 211 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 142.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 142.7749939 16.35000038 l h f* Q q 1 0 0 1 142.3999939 0 cm -0.625 -0.25 m 281.0249939 -0.25 l 281.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 212 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Syn)-1(t)1(hesized)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 51.35400009 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 55.85400009 11.72200012 Tm [(pept)1(ide)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 89.06800079 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 93.56800079 11.72200012 Tm [(derived)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 125.84999847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 130.3500061 11.72200012 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 151.06100464 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 155.56100464 11.72200012 Tm [(internal)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 188.31300354 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 192.81300354 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 201.65499878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 206.15499878 11.72200012 Tm [(human)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 236.19599915 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 240.69599915 11.72200012 Tm [(Cof)1(il)-1(in.)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 270.45599365 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 174.60002136 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 142.3999939 0.75 m 142.3999939 125.55000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 142.3999939 126.30000305 m 142.3999939 141.90000916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 142.3999939 142.65000916 m 142.3999939 158.25001526 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 142.3999939 159.00001526 m 142.3999939 174.60002136 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 174.60002136 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 125.92500305 m 422.42498779 125.92500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 142.27500916 m 422.42498779 142.27500916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 158.62501526 m 422.42498779 158.62501526 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 174.97502136 m 423.17498779 174.97502136 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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