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[<0009000A000B000C000D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 76.125 12.82499981 Tm [(CF)-1(I)] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 91.81900024 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 144.31900024 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 154.81900024 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CFI)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 96.80200195 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 99.1760025 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 124.8259964 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 127.19999695 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 170.75900269 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 173.13299561 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 210.92900085 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(FI;)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 73.27999878 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 75.65399933 12.82499981 Tm [(IF;)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 85.93399811 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 88.30799866 12.82499981 Tm [(KA)1(F)-1(;)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 107.47299957 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 109.84700012 12.82499981 Tm [(AHU)1(S)-1(3;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 142.15699768 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 144.53100586 12.82499981 Tm [(ARMD13)1(;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 185.19799805 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 187.57200623 12.82499981 Tm [(C3BIN)1(A;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 222.51199341 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 224.88600159 12.82499981 Tm [(C3b-)-1(IN)1(A)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 260.03601074 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0010000D>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CF)-1(I)] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 76.06900024 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0012000D>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001300140015>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<00160017>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<00180019>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001B000D>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 61 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F000D>] TJ ET EMC /P <</MCID 62 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002000210022000F000D>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00230004>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 70 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002400250026000D>] TJ ET EMC /P <</MCID 71 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700220027000D>] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 79 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 80 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 81 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 82 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 160.0249939 0.75 l 160.0249939 125.55000305 l 0.375 125.55000305 l h f* Q q -0.625 -0.25 m 161.0249939 -0.25 l 161.0249939 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 83 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 66.3219986 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 84 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 66.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 160.7749939 0.75 m 422.42498779 0.75 l 422.42498779 125.55000305 l 160.7749939 125.55000305 l h f* Q q 1 0 0 1 160.3999939 0 cm -0.625 -0.25 m 263.0249939 -0.25 l 263.0249939 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 85 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(serine)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 123.4260025 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 127.9260025 11.72200012 Tm [(pro)1(tein)-1(a)1(se)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 173.47999573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 177.97999573 11.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 195.20199585 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 199.70199585 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 206.26300049 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 210.76300049 11.72200012 Tm [(esse)-1(nt)1(ial)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 247.97099304 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 12.27799988 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 16.77799988 27.3220005 Tm [(regulat)1(i)-1(ng)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 61.04399872 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 65.54399872 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 79.54499817 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 84.04499817 27.3220005 Tm [(compleme)-1(nt)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 138.40100098 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 142.90100098 27.3220005 Tm [(casc)-1(a)1(de.)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 179.07200623 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 183.57200623 27.3220005 Tm [(The)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 199.3789978 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 203.8789978 27.3220005 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 241.38600159 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 245.88600159 27.3220005 Tm [(p)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(repro)1(prot)1(e)-1(in)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 54.75600052 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 59.25600052 42.92200089 Tm [(is)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 65.81700134 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 70.31700134 42.92200089 Tm [(cl)-1(eaved)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 102.89399719 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 107.39399719 42.92200089 Tm [(to)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 116.46900177 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 120.96900177 42.92200089 Tm [(pro)1(duc)-1(e)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 156.79800415 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 161.29800415 42.92200089 Tm [(bo)1(th)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 181.66200256 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 186.16200256 42.92200089 Tm [(heavy)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 211.27200317 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 215.77200317 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 232.04899597 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 236.54899597 42.92200089 Tm [(ligh)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(t)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 3.35299993 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 7.85300016 58.52199936 Tm [(chains,)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 37.15599823 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 41.65599823 58.52199936 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 66.75299835 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 71.25299835 58.52199936 Tm [(are)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 84.77100372 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 89.27100372 58.52199936 Tm [(link)-1(ed)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 115.37000275 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 119.87000275 58.52199936 Tm [(by)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 130.38200378 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 134.88200378 58.52199936 Tm [(disulfid)1(e)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 171.51899719 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 176.01899719 58.52199936 Tm [(bo)1(n)-1(d)1(s)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 202.95700073 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 207.45700073 58.52199936 Tm [(to)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 216.53199768 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 221.03199768 58.52199936 Tm [(fo)1(rm)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 241.74299622 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 246.24299622 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 251.21800232 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(heterod)1(ime)-1(ric)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 60.30199814 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 64.80200195 74.12200165 Tm [(glyc)-1(o)1(prot)1(ei)-1(n.)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 121.4260025 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 125.9260025 74.12200165 Tm [(This)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 143.18800354 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 147.68800354 74.12200165 Tm [(heterod)1(ime)-1(r)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 201.08200073 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 205.58200073 74.12200165 Tm [(can)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 220.61599731 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 225.11599731 74.12200165 Tm [(cl)-1(eave)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 251.93600464 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 16.27700043 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 20.77700043 89.72200012 Tm [(inac)-1(t)1(ivat)1(e)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 62.11199951 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 66.61199951 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 80.61299896 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 85.11299896 89.72200012 Tm [(compleme)-1(nt)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 139.46899414 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 143.96899414 89.72200012 Tm [(components)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 197.82400513 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 202.32400513 89.72200012 Tm [(C4b)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 219.36999512 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 223.86999512 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 240.14700317 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 244.64700317 89.72200012 Tm [(C)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(3b,)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 13.19200039 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 17.69199944 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 33.96900177 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 38.46900177 105.3219986 Tm [(it)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 44.21699905 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 48.71699905 105.3219986 Tm [(prevents)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 85.90399933 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 90.40399933 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 104.40499878 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 108.90499878 105.3219986 Tm [(assembly)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 148.65800476 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 153.15800476 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 162 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 166.5 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 180.50100708 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 185.00100708 105.3219986 Tm [(C3)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 196.29899597 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 200.79899597 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 217.07600403 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 221.57600403 105.3219986 Tm [(C5)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 232.87399292 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 237.37399292 105.3219986 Tm [(con)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(verta)1(se)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 30.86700058 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 35.36700058 120.92199707 Tm [(en)-1(z)1(y)-1(mes.)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 75.08000183 120.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 125.55000305 cm q /GS2 gs 1 g 0.375 0.75 m 160.0249939 0.75 l 160.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 161.0249939 -0.25 l 161.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 211 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 212 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 160.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 160.7749939 16.35000038 l h f* Q q 1 0 0 1 160.3999939 0 cm -0.625 -0.25 m 263.0249939 -0.25 l 263.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 213 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 14.80500031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 141.8999939 cm q /GS2 gs 1 g 0.375 0.75 m 160.0249939 0.75 l 160.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 161.0249939 -0.25 l 161.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 215 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 220 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 160.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 160.7749939 16.35000038 l h f* Q q 1 0 0 1 160.3999939 0 cm -0.625 -0.25 m 263.0249939 -0.25 l 263.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 221 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CFI)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 13.44699955 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 158.25 cm q /GS2 gs 1 g 0.375 0.75 m 160.0249939 0.75 l 160.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 161.0249939 -0.25 l 161.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 223 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 224 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 160.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 160.7749939 16.35000038 l h f* Q q 1 0 0 1 160.3999939 0 cm -0.625 -0.25 m 263.0249939 -0.25 l 263.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 225 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Syn)-1(t)1(hesized)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 51.35400009 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 55.85400009 11.72200012 Tm [(pept)1(ide)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 89.06800079 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 93.56800079 11.72200012 Tm [(derived)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 125.84999847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 130.3500061 11.72200012 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 151.06100464 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 155.56100464 11.72200012 Tm [(internal)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 188.31300354 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 192.81300354 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 201.65499878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 206.15499878 11.72200012 Tm [(human)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 236.19599915 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 240.69599915 11.72200012 Tm [(CFI)] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 174.60002136 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 160.3999939 0.75 m 160.3999939 125.55000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 160.3999939 126.30000305 m 160.3999939 141.90000916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 160.3999939 142.65000916 m 160.3999939 158.25001526 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 160.3999939 159.00001526 m 160.3999939 174.60002136 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 174.60002136 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 125.92500305 m 422.42498779 125.92500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 142.27500916 m 422.42498779 142.27500916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 158.62501526 m 422.42498779 158.62501526 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 174.97502136 m 423.17498779 174.97502136 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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