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[<0009000A000B000C>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 65.80999756 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 89.43499756 12.82499981 Tm [(CF)-1(C1)] TJ ET EMC /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 113.40399933 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 165.90400696 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 176.40400696 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 12 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000D000A000B000C>] TJ ET EMC /P <</MCID 13 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 55.31000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CFC1)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 105.07700348 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 107.4509964 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 133.10099792 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 135.4750061 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 179.03399658 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 181.40800476 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 219.20399475 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 24 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E>] TJ ET EMC /P <</MCID 25 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 26 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000B>] TJ ET EMC /P <</MCID 27 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(HTX2;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 88.23999786 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 90.61399841 12.82499981 Tm [(CF)-1(C1B;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 120.47899628 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 122.85299683 12.82499981 Tm [(DT)-1(G)1(A2;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 155.25999451 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 157.63400269 12.82499981 Tm [(CRYPTIC)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 192.83599854 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(   )] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [<000F>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 36.75 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 39.56000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 41.93399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 42 12.82499981 Tm /GS2 gs 0 g [(CF)-1(C1)] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 63.34400177 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(   )] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [<0011>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 36.75 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 39.56000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 41.93399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS2 gs 0 g [<001200130014>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 73.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 87.35800171 12.82499981 Tm [<00150016>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(   )] TJ ET EMC /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [<0018>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 36.75 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 39.56000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 41.93399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 42 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 69.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 84 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0019001A001B001C>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 71 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001D001E001F000E>] TJ ET EMC /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00200004>] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 77 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0021>] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 79 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0022>] TJ ET EMC /P <</MCID 80 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 81 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0023>] TJ ET EMC /P <</MCID 82 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 88 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<00060007001F0024>] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 95 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 96 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 97 >> BDC BT /FAAACI 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 98 >> BDC BT /FAAADC 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 99 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 12.89099979 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 159.2749939 0.75 l 159.2749939 109.94999695 l 0.375 109.94999695 l h f* Q q -0.625 -0.25 m 160.2749939 -0.25 l 160.2749939 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 100 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 58.52199936 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 101 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 57.29199982 58.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 160.0249939 0.75 m 422.42498779 0.75 l 422.42498779 109.94999695 l 160.0249939 109.94999695 l h f* Q q 1 0 0 1 159.6499939 0 cm -0.625 -0.25 m 263.7749939 -0.25 l 263.7749939 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 102 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC 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165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(epidermal)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 213.6289978 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 218.1289978 11.72200012 Tm [(gr)1(owt)1(h)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 249.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 25.11899948 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 29.61899948 27.3220005 Tm [(\(EG)1(F)-1(\)-)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 55.9469986 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 60.4469986 27.3220005 Tm [(Cript)1(o,)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 89.28800201 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 93.78800201 27.3220005 Tm [(Frl-1,)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 115.73899841 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 120.23899841 27.3220005 Tm [(and)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 136.51600647 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 141.01600647 27.3220005 Tm [(Crypt)1(ic)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 171.2460022 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 175.7460022 27.3220005 Tm [(\(CFC\))] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 198.58000183 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 203.08000183 27.3220005 Tm [(fa)1(mi)-1(ly,)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 231.32800293 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 235.82800293 27.3220005 Tm [(wh)1(ic)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(h)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 5.54199982 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 10.04199982 42.92200089 Tm [(are)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 23.55999947 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 28.05999947 42.92200089 Tm [(involved)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 64.42900085 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 68.92900085 42.92200089 Tm [(in)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 76.87000275 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 81.37000275 42.92200089 Tm [(signalling)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 122.69599915 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 127.19599915 42.92200089 Tm [(during)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 155.63299561 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 160.13299561 42.92200089 Tm [(embryonic)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 205.79699707 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 210.29699707 42.92200089 Tm [(developm)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(en)-1(t)1(.)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 16.17200089 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 20.67200089 58.52199936 Tm [(Pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 55.90299988 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 60.40299988 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 68.34400177 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 72.84400177 58.52199936 Tm [(th)1(is)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 88.30000305 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 92.80000305 58.52199936 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 118.88200378 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 123.38200378 58.52199936 Tm [(sha)1(re)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 146.60699463 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 151.10699463 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 156.08200073 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 160.58200073 58.52199936 Tm [(var)1(i)-1(a)1(n)-1(t)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 189.98599243 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 194.48599243 58.52199936 Tm [(EG)1(F)-1(-)1(li)-1(ke)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 229.5980072 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 234.0980072 58.52199936 Tm [(mot)1(i)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(f,)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 5.28700018 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 9.7869997 74.12200165 Tm [(a)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 14.76200008 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 19.26199913 74.12200165 Tm [(conse)-1(rv)1(e)-1(d)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 63.3390007 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 67.83899689 74.12200165 Tm [(cy)-1(st)1(e)-1(ine-rich)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 122.56800079 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 127.06800079 74.12200165 Tm [(do)1(main,)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 162.06199646 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 166.56199646 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 182.83900452 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 187.33900452 74.12200165 Tm [(a)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 192.31399536 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 196.81399536 74.12200165 Tm [(C-t)1(e)-1(r)1(min)-1(a)1(l)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 242.36799622 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 246.86799622 74.12200165 Tm [(h)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ydrop)1(hob)1(ic)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 49.34600067 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 53.84600067 89.72200012 Tm [(region.)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 83.97499847 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 88.47499847 89.72200012 Tm [(The)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 104.28199768 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 108.78199768 89.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 140.08900452 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 144.58900452 89.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 182.09599304 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 186.59599304 89.72200012 Tm [(by)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 197.10800171 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 201.60800171 89.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 217.06399536 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 221.56399536 89.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 243.08000183 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 247.58000183 89.72200012 Tm [(is)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 254.14100647 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ne)-1(cessary)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 41.77899933 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 46.27899933 105.3219986 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 58.55699921 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 63.05699921 105.3219986 Tm [(pa)1(tterning)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 108.27200317 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 112.77200317 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 126.77300262 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 131.272995 105.3219986 Tm [(left-)1(right)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 169.62399292 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 174.12399292 105.3219986 Tm [(embryonic)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 219.78799438 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 224.28799438 105.3219986 Tm [(axis.)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 242.55200195 105.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 109.94999695 cm q /GS2 gs 1 g 0.375 0.75 m 159.2749939 0.75 l 159.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 160.2749939 -0.25 l 160.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 220 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 221 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 160.0249939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 160.0249939 16.35000038 l h f* Q q 1 0 0 1 159.6499939 0 cm -0.625 -0.25 m 263.7749939 -0.25 l 263.7749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 222 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ELISA,)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 25.90600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 30.40600014 11.72200012 Tm [(WB,)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 47.37799835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 51.87799835 11.72200012 Tm [(IHC)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 67.50499725 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 126.30000305 cm q /GS2 gs 1 g 0.375 0.75 m 159.2749939 0.75 l 159.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 160.2749939 -0.25 l 160.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 228 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 233 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 160.0249939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 160.0249939 16.35000038 l h f* Q q 1 0 0 1 159.6499939 0 cm -0.625 -0.25 m 263.7749939 -0.25 l 263.7749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 234 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CFC1)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 22.10000038 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 142.6499939 cm q /GS2 gs 1 g 0.375 0.75 m 159.2749939 0.75 l 159.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 160.2749939 -0.25 l 160.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 236 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 237 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 160.0249939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 160.0249939 16.35000038 l h f* Q q 1 0 0 1 159.6499939 0 cm -0.625 -0.25 m 263.7749939 -0.25 l 263.7749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 238 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Syn)-1(t)1(hetic)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 39.76599884 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 44.26599884 11.72200012 Tm [(pept)1(ide)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 77.48000336 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 81.98000336 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 90.8219986 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 95.3219986 11.72200012 Tm [(human)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 125.36299896 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 129.86300659 11.72200012 Tm [(CFC1)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 151.96299744 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 159 cm q /GS2 gs 1 g 0.375 0.75 m 159.2749939 0.75 l 159.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 160.2749939 -0.25 l 160.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 248 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 251 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 160.0249939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 160.0249939 16.35000038 l h f* Q q 1 0 0 1 159.6499939 0 cm -0.625 -0.25 m 263.7749939 -0.25 l 263.7749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 252 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(cripto)1(,)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 27.33399963 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 31.83399963 11.72200012 Tm [(FRL-1,)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 58.4469986 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 62.9469986 11.72200012 Tm [(cry)-1(p)1(tic)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 91.66999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 96.16999817 11.72200012 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 122.2519989 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 126.7519989 11.72200012 Tm [(1)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 132.02999878 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 175.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 159.6499939 0.75 m 159.6499939 109.94999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 159.6499939 110.69999695 m 159.6499939 126.29999542 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 159.6499939 127.04999542 m 159.6499939 142.6499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 159.6499939 143.3999939 m 159.6499939 159 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 159.6499939 159.75 m 159.6499939 175.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 175.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 110.32499695 m 422.42498779 110.32499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 126.67499542 m 422.42498779 126.67499542 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 143.0249939 m 422.42498779 143.0249939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 159.375 m 422.42498779 159.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 175.7250061 m 423.17498779 175.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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