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1 0 0 -1 -110 61.9640007 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -57.5 61.9640007 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -47 61.9640007 Tm [<00030004>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -23.375 61.9640007 Tm [(CF)-1(B)] TJ ET EMC /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -4.61499786 61.9640007 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 47.88499451 61.9640007 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 53.13499451 61.9640007 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 82.6780014 cm /P <</Lang (zh-CN) /MCID 12 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 13 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 57.75 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CFB)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 99.86799622 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 102.24199677 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 127.89199829 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 130.26600647 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 173.82499695 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 176.19900513 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 213.99499512 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 116.21700287 cm /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 25 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 26 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(BF;)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 76.34500122 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 78.71900177 12.82499981 Tm [(FB;)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 92.06400299 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 94.43800354 12.82499981 Tm [(BFD)-1(;)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 114.24299622 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 116.61699677 12.82499981 Tm [(GBG;)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 138.38600159 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 140.75999451 12.82499981 Tm [(CF)-1(A)1(B;)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 165.77999878 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 168.15400696 12.82499981 Tm [(CF)-1(BD;)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 193.55799866 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 195.93200684 12.82499981 Tm [(PBF2;)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 220.02400208 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 222.397995 12.82499981 Tm [(AHU)1(S)-1(4;)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 254.70799255 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 257.08200073 12.82499981 Tm [(FBI12;)] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 283.7170105 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 286.09100342 12.82499981 Tm [(H2-Bf;)] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 312.89498901 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 315.26901245 12.82499981 Tm [(ARMD14)] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 353.12600708 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 149.7559967 cm /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 52 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 183.29499817 cm /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0004>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0014000D>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CF)-1(B)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 79.13500214 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 216.83399963 cm /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0015>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000D>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 64 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 65 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 66 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 67 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 250.3730011 cm /P <</Lang (zh-CN) /MCID 68 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C>] TJ ET EMC /P <</MCID 69 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 70 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000D>] TJ ET EMC /P <</MCID 71 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 283.9119873 cm /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 128.3480072 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 317.45098877 cm /P <</Lang (zh-CN) /MCID 81 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0022>] TJ ET EMC /P <</MCID 82 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 83 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0023>] TJ ET EMC /P <</MCID 84 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 85 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0024000D>] TJ ET EMC /P <</MCID 86 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 350.98999023 cm /P <</Lang (zh-CN) /MCID 90 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0006000700120025000D>] TJ ET EMC /P <</MCID 91 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 384.5289917 m 416.75 384.5289917 l 416.75 415.72900391 l -1.45000005 415.72900391 l h f* Q q 1 0 0 1 0 384.5289917 cm /P <</MCID 96 >> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 97 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 98 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 415.72900391 cm /P <</MCID 99 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 443.66799927 cm q 1 g 0.375 0.75 m 147.2749939 0.75 l 147.2749939 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 148.2749939 -0.25 l 148.2749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 100 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 101 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 148.0249939 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 148.0249939 172.3500061 l h f* Q q 1 0 0 1 147.6499939 0 cm -0.625 -0.25 m 275.7749939 -0.25 l 275.7749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 102 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(This)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(compleme)-1(nt)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 142.55099487 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 147.05099487 11.72200012 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 172.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 176.66999817 11.72200012 Tm [(B,)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 184.48300171 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 188.98300171 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 193.95799255 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 198.45799255 11.72200012 Tm [(component)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 248.14700317 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 252.64700317 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 261.48901367 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 14.0010004 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 18.50099945 27.3220005 Tm [(alt)1(e)-1(rnat)1(ive)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 63.86600113 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 68.36599731 27.3220005 Tm [(pa)1(thw)1(ay)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 104.82700348 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 109.32700348 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 118.16899872 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 122.66899872 27.3220005 Tm [(compleme)-1(nt)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 177.0249939 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 181.5249939 27.3220005 Tm [(activat)1(ion.)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 225.64199829 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 230.14199829 27.3220005 Tm [(Factor)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 256.92199707 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 261.42199707 27.3220005 Tm [(B)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 267.06900024 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ci)-1(r)1(c)-1(ulat)1(e)-1(s)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 40.39899826 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 44.89899826 42.92200089 Tm [(in)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 52.84000015 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 57.34000015 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 71.34100342 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 75.84100342 42.92200089 Tm [(bloo)1(d)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 101.18399811 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 105.68399811 42.92200089 Tm [(as)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 114.82499695 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 119.32499695 42.92200089 Tm [(a)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 124.30000305 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 128.80000305 42.92200089 Tm [(single)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 154.16499329 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 158.66499329 42.92200089 Tm [(chain)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 181.63499451 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 186.13499451 42.92200089 Tm [(po)1(l)-1(yp)1(e)-1(pt)1(ide.)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 240.14399719 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 244.64399719 42.92200089 Tm [(Up)1(o)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(n)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 5.546 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 10.04599953 58.52199936 Tm [(activat)1(ion)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 51.99599838 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 56.49599838 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 65.33799744 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 69.83799744 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 83.83899689 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 88.33899689 58.52199936 Tm [(alt)1(e)-1(rnat)1(ive)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 133.70399475 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 138.20399475 58.52199936 Tm [(pa)1(thw)1(ay,)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 176.83200073 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 181.33200073 58.52199936 Tm [(it)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 187.08000183 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 191.58000183 58.52199936 Tm [(is)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 198.14100647 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 202.64100647 58.52199936 Tm [(cl)-1(eaved)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 235.21800232 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 239.71800232 58.52199936 Tm [(by)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 250.22999573 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 254.72999573 58.52199936 Tm [(co)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(mpleme)-1(nt)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 44.12099838 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 48.62099838 74.12200165 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 73.73999786 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 78.23999786 74.12200165 Tm [(D)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 85.09500122 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 89.59500122 74.12200165 Tm [(yie)-1(lding)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 123.70999908 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 128.21000671 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 142.21099854 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 146.71099854 74.12200165 Tm [(nonc)-1(a)1(talytic)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 198.75999451 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 203.25999451 74.12200165 Tm [(chain)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 226.22999573 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 230.72999573 74.12200165 Tm [(Ba)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 241.352005 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 245.852005 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 262.1289978 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 14.0010004 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 18.50099945 89.72200012 Tm [(cata)1(l)-1(yt)1(i)-1(c)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 53.73600006 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 58.23600006 89.72200012 Tm [(subunit)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 90.53600311 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 95.03600311 89.72200012 Tm [(Bb.)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 108.59799957 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 113.09799957 89.72200012 Tm [(The)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 128.90499878 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 133.40499878 89.72200012 Tm [(active)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 158.47099304 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 162.97099304 89.72200012 Tm [(subunit)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 195.27099609 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 199.77099609 89.72200012 Tm [(Bb)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 211.16600037 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 215.66600037 89.72200012 Tm [(is)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 222.227005 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 226.727005 89.72200012 Tm [(a)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 231.70199585 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 236.20199585 89.72200012 Tm [(serine)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 261.95800781 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(pro)1(tease)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 37.61299896 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 42.11299896 105.3219986 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 67.20999908 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 71.70999908 105.3219986 Tm [(asso)1(c)-1(iat)1(e)-1(s)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 115.24700165 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 119.74700165 105.3219986 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 138.14300537 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 142.64300537 105.3219986 Tm [(C3b)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 159.68899536 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 164.18899536 105.3219986 Tm [(to)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 173.26400757 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 177.76400757 105.3219986 Tm [(fo)1(rm)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 198.4750061 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 202.9750061 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 216.97599792 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 221.47599792 105.3219986 Tm [(alt)1(e)-1(rnat)1(ive)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 266.84100342 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(pa)1(thw)1(ay)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 36.46099854 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 40.96099854 120.92199707 Tm [(C3)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 52.25899887 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 56.75899887 120.92199707 Tm [(conve)-1(rt)1(ase.)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 105.57299805 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 110.07299805 120.92199707 Tm [(Bb)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 121.46800232 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 125.96800232 120.92199707 Tm [(is)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 132.52900696 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 137.02900696 120.92199707 Tm [(involved)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 173.397995 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 177.897995 120.92199707 Tm [(in)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 185.83900452 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 190.33900452 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 204.33999634 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 208.83999634 120.92199707 Tm [(pro)1(life)-1(r)1(ation)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 262.19000244 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 8.84200001 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 13.34200001 136.52200317 Tm [(preactiva)1(ted)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 66.78399658 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 71.28399658 136.52200317 Tm [(B)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 76.93099976 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 81.43099976 136.52200317 Tm [(lymphocytes,)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 138.10299683 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 142.60299683 136.52200317 Tm [(wh)1(il)-1(e)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 165.14700317 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 169.64700317 136.52200317 Tm [(Ba)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 180.26899719 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 184.76899719 136.52200317 Tm [(inhibits)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 216.30900574 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 220.80900574 136.52200317 Tm [(th)1(e)-1(ir)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 240.64199829 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 245.14199829 136.52200317 Tm [(pro)1(li)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(ferat)1(ion.)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 35.81999969 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 40.31999969 152.12199402 Tm [(This)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 57.58200073 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 62.08200073 152.12199402 Tm [(gene)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 83.59799957 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 88.09799957 152.12199402 Tm [(localizes)] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 124.19000244 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 128.69000244 152.12199402 Tm [(to)] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 137.76499939 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 142.26499939 152.12199402 Tm [(th)1(e)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 156.26600647 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 160.76600647 152.12199402 Tm [(major)] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 185.73599243 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 190.23599243 152.12199402 Tm [(hist)1(ocompat)1(ibility)] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 267.60198975 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(complex)] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 36.47900009 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 40.97900009 167.72200012 Tm [(\(MHC\))] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 68.76599884 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 73.26599884 167.72200012 Tm [(cl)-1(a)1(ss)] TJ ET EMC /P <</MCID 290 >> BDC BT 1 0 0 -1 93.48100281 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 291 >> BDC BT 1 0 0 -1 97.98100281 167.72200012 Tm [(III)] TJ ET EMC /P <</MCID 292 >> BDC BT 1 0 0 -1 105.91799927 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 293 >> BDC BT 1 0 0 -1 110.41799927 167.72200012 Tm [(region)] TJ ET EMC /P <</MCID 294 >> BDC BT 1 0 0 -1 138.38000488 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 295 >> BDC BT 1 0 0 -1 142.88000488 167.72200012 Tm [(on)] TJ ET EMC /P <</MCID 296 >> BDC BT 1 0 0 -1 154.147995 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 297 >> BDC BT 1 0 0 -1 158.647995 167.72200012 Tm [(chromos)1(ome)] TJ ET EMC /P <</MCID 298 >> BDC BT 1 0 0 -1 215.44299316 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 299 >> BDC BT 1 0 0 -1 219.94299316 167.72200012 Tm [(6.)] TJ ET EMC /P <</MCID 300 >> BDC BT 1 0 0 -1 227.38699341 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 301 >> BDC BT 1 0 0 -1 231.88699341 167.72200012 Tm [(This)] TJ ET EMC /P <</MCID 302 >> BDC BT 1 0 0 -1 249.14900208 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 303 >> BDC BT 1 0 0 -1 253.64900208 167.72200012 Tm [(cl)-1(u)] TJ ET EMC Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 172.3500061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 147.6499939 0.75 m 147.6499939 172.3500061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 172.3500061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 172.7250061 m 423.17498779 172.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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6 0 obj
<</Length1 122 0 R/Length 28948>>stream
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