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[<0009000A000B000C000D>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 86.625 12.82499981 Tm [(CERS)-1(1)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 115.82299805 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 168.32299805 12.82499981 Tm [(   )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 184.07299805 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CERS)-1(1)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 110.30599976 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 112.68000031 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 138.33000183 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 140.70399475 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 184.26300049 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 186.63699341 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 224.43299866 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(LAG1;)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 88.24500275 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 90.6190033 12.82499981 Tm [(UOG1)1(;)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 119.06300354 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 121.43699646 12.82499981 Tm [(LASS)-1(1)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 146.89700317 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 31 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 32 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 33 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 34 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0015000D>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001B>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001C000D>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 52 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000D>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CERS)-1(1)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 89.57299805 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 57 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 58 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 128.3480072 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 63 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0022>] TJ ET EMC /P <</MCID 64 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0023>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0024000D>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 72 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700120025000D>] TJ ET EMC /P <</MCID 73 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 78 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 79 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 80 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 81 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 151.0249939 0.75 l 151.0249939 141.1499939 l 0.375 141.1499939 l h f* Q q -0.625 -0.25 m 152.0249939 -0.25 l 152.0249939 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 82 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 74.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 83 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 151.7749939 0.75 m 422.42498779 0.75 l 422.42498779 141.1499939 l 151.7749939 141.1499939 l h f* Q q 1 0 0 1 151.3999939 0 cm -0.625 -0.25 m 272.0249939 -0.25 l 272.0249939 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 84 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(bo)1(n)-1(e)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 192.39900208 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 196.89900208 11.72200012 Tm [(morp)1(hog)1(e)-1(netic)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 263.27801514 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 31.30699921 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 35.80699921 27.3220005 Tm [(\(BMP\))] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 61.76499939 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 66.26499939 27.3220005 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 92.34700012 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 96.84700012 27.3220005 Tm [(and)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 113.12400055 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 117.62400055 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 131.625 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 136.125 27.3220005 Tm [(TGF-b)1(e)-1(t)1(a)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 175.83399963 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 180.33399963 27.3220005 Tm [(superfa)1(mi)-1(ly.)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 232.58500671 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 237.08500671 27.3220005 Tm [(This)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 254.34700012 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(gr)1(oup)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 26.20899963 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 30.70899963 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 39.55099869 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 44.05099869 42.92200089 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 79.52400208 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 84.02400208 42.92200089 Tm [(is)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 90.58499908 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 95.08499908 42.92200089 Tm [(chara)1(c)-1(terized)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 152.61799622 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 157.11799622 42.92200089 Tm [(by)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 167.63000488 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 172.13000488 42.92200089 Tm [(a)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 177.10499573 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 181.60499573 42.92200089 Tm [(po)1(l)-1(yb)1(asic)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 222.02999878 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 226.52999878 42.92200089 Tm [(pro)1(teoly)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(tic)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 10.26099968 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 14.76099968 58.52199936 Tm [(pro)1(c)-1(essing)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 61.31700134 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 65.81700134 58.52199936 Tm [(site)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 80.83799744 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 85.33799744 58.52199936 Tm [(th)1(at)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 102.55999756 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 107.05999756 58.52199936 Tm [(is)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 113.6210022 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 118.1210022 58.52199936 Tm [(cl)-1(eaved)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 150.69799805 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 155.19799805 58.52199936 Tm [(to)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 164.272995 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 168.772995 58.52199936 Tm [(pro)1(duc)-1(e)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 204.602005 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 209.102005 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 214.07699585 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 218.57699585 58.52199936 Tm [(mat)1(u)-1(r)1(e)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 249.42700195 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 253.92700195 58.52199936 Tm [(pr)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ot)1(e)-1(in)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 22.12199974 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 26.62199974 74.12200165 Tm [(containing)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 72.3690033 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 76.8690033 74.12200165 Tm [(seve)-1(n)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 101.51799774 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 106.01799774 74.12200165 Tm [(conse)-1(rv)1(e)-1(d)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 150.09500122 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 154.59500122 74.12200165 Tm [(cy)-1(st)1(e)-1(ine)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 189.54499817 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 194.04499817 74.12200165 Tm [(residues.)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 231.89100647 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 236.39100647 74.12200165 Tm [(Mem)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(bers)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 18.45700073 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 22.95700073 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 31.79899979 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 36.29899979 89.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 51.75500107 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 56.25500107 89.72200012 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 82.33699799 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 86.83699799 89.72200012 Tm [(are)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 100.35500336 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 104.85500336 89.72200012 Tm [(regulat)1(ors)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 148.7480011 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 153.2480011 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 162.08999634 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 166.58999634 89.72200012 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 181 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 185.5 89.72200012 Tm [(gr)1(owt)1(h)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 216.41600037 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 220.91600037 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 237.19299316 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 241.69299316 89.72200012 Tm [(dif)1(fe)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(rentiat)1(i)-1(o)1(n)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 41.82699966 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 46.32699966 105.3219986 Tm [(in)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 54.26800156 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 58.76800156 105.3219986 Tm [(bo)1(th)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 79.13200378 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 83.63200378 105.3219986 Tm [(embryonic)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 129.29600525 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 133.79600525 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 150.07299805 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 154.57299805 105.3219986 Tm [(ad)1(u)-1(lt)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 176.5980072 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 181.0980072 105.3219986 Tm [(tiss)1(u)-1(es.)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 212.16299438 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 216.66299438 105.3219986 Tm [(Studies)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 248.18099976 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 252.68099976 105.3219986 Tm [(in)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 260.62200928 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(ye)-1(a)1(st)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 22.36400032 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 26.86400032 120.92199707 Tm [(sugg)1(e)-1(st)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 60.71500015 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 65.21499634 120.92199707 Tm [(th)1(at)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 82.43699646 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 86.93699646 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 100.93800354 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 105.43800354 120.92199707 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 142.94500732 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 147.44500732 120.92199707 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 178.7519989 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 183.2519989 120.92199707 Tm [(is)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 189.81300354 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 194.31300354 120.92199707 Tm [(involved)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 230.68200684 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 235.18200684 120.92199707 Tm [(in)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 243.1230011 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 247.6230011 120.92199707 Tm [(ag)1(i)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(ng.)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 13.46899986 136.52200317 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 141.1499939 cm q /GS2 gs 1 g 0.375 0.75 m 151.0249939 0.75 l 151.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 152.0249939 -0.25 l 152.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 229 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 230 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 151.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 151.7749939 16.35000038 l h f* Q q 1 0 0 1 151.3999939 0 cm -0.625 -0.25 m 272.0249939 -0.25 l 272.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 231 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ELISA,)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 25.90600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 30.40600014 11.72200012 Tm [(WB,)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 47.37799835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 51.87799835 11.72200012 Tm [(IHC)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 67.50499725 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 157.5 cm q /GS2 gs 1 g 0.375 0.75 m 151.0249939 0.75 l 151.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 152.0249939 -0.25 l 152.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 237 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 242 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 151.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 151.7749939 16.35000038 l h f* Q q 1 0 0 1 151.3999939 0 cm -0.625 -0.25 m 272.0249939 -0.25 l 272.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 243 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CERS1)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 27.31599998 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 151.3999939 0.75 m 151.3999939 141.1499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 151.3999939 141.8999939 m 151.3999939 157.5 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 151.3999939 158.25 m 151.3999939 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 141.5249939 m 422.42498779 141.5249939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.875 m 422.42498779 157.875 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 174.2250061 m 423.17498779 174.2250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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