%PDF-1.5 %ÈÈÈÈÈÈ?1 0 obj <> endobj 2 0 obj <>/Metadata 132 0 R>> endobj 3 0 obj <> endobj 4 0 obj <>/ExtGState<>/XObject<>>>/Group<>/StructParents 0/Tabs/S>> endobj 5 0 obj <>stream 1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.20001221 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm q 1 0 0 1 110 0 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 0 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 49.67599869 23.67700005 Tm 0 Tr [(EI)1(F3H)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 106.90000153 23.67700005 Tm 2 Tr [<0005>-4<0006>-4<0007>-4<0004>-4<0008>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 217.33999634 23.67700005 Tm 0 Tr [( )] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 228.33999634 23.67700005 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 -110 43.75799942 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -110 61.9640007 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <> BDC BT 1 0 0 -1 -57.5 61.9640007 Tm [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -33.875 61.9640007 Tm [(EIF)-1(3H)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -6.78900146 61.9640007 Tm [<00050006000700040008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 45.71099854 61.9640007 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.96099854 61.9640007 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 82.6780014 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000E000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(EIF3H)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.19400024 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.56800079 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.21800232 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.59199524 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.15100098 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.5249939 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.32099915 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 116.21700287 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(EIF)-1(3S3;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.875 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.24900055 12.82499981 Tm [(eIF3-p40;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.44900513 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.82299805 12.82499981 Tm [(eIF3-gamm)1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.83099365 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 149.7559967 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001000110012000F000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 183.29499817 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0014>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0015000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 216.83399963 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001B000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(EIF)-1(3H)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.46099854 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 250.3730011 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001D000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 283.9119873 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001E001F00200021000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.96800232 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.34199524 12.82499981 Tm [(Rat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.58999634 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 317.45098877 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<002200230024000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 350.98999023 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0006000700120025000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 384.5289917 m 416.75 384.5289917 l 416.75 415.72900391 l -1.45000005 415.72900391 l h f* Q q 1 0 0 1 0 384.5289917 cm /P <> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 415.72900391 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 443.66799927 cm q 1 g 0.375 0.75 m 156.2749939 0.75 l 156.2749939 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 157.2749939 -0.25 l 157.2749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 157.0249939 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 157.0249939 172.3500061 l h f* Q q 1 0 0 1 156.6499939 0 cm -0.625 -0.25 m 266.7749939 -0.25 l 266.7749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Eukaryotic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.55199814 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.05199814 11.72200012 Tm [(tr)1(anslatio)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.91300201 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.41300201 11.72200012 Tm [(initiat)1(i)-1(o)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.48699951 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.98699951 11.72200012 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.10600281 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.60600281 11.72200012 Tm [(3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.88400269 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.38400269 11.72200012 Tm [(subunit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.68400574 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.18400574 11.72200012 Tm [(H)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.14500427 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.64500427 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.20599365 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.70599365 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.68099976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.18099976 11.72200012 Tm [(p)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(rot)1(e)-1(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.55900002 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.05900002 27.3220005 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.28099823 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.78099823 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.72200012 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.22200012 27.3220005 Tm [(humans)] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.42900085 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.92900085 27.3220005 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.48999786 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.98999786 27.3220005 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.49699402 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.99699402 27.3220005 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.50900269 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.00900269 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.00999451 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.50999451 27.3220005 Tm [(EIF3H)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.12399292 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.62399292 27.3220005 Tm [(gene)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.30599976 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.80599976 27.3220005 Tm [(Co)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(mpo)1(n)-1(ent)] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.45399857 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.95399857 42.92200089 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.79600143 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.29600143 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.29699707 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.79699707 42.92200089 Tm [(eu)-1(karyot)1(ic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.50700378 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.00700378 42.92200089 Tm [(tr)1(anslatio)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.86799622 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.36799622 42.92200089 Tm [(initiat)1(i)-1(o)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.44200134 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.94200134 42.92200089 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.06100464 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.56100464 42.92200089 Tm [(3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.83900452 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(\(eIF)-1(-)1(3)-1(\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.7159996 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.2159996 58.52199936 Tm [(complex,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.86199951 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.36199951 58.52199936 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.45899963 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.95899963 58.52199936 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.51999664 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.01999664 58.52199936 Tm [(required)] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.56100464 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.06100464 58.52199936 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.33900452 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.83900452 58.52199936 Tm [(seve)-1(r)1(al)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.7480011 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.2480011 58.52199936 Tm [(st)1(e)-1(ps)] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.78799438 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.28799438 58.52199936 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.22900391 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.72900391 58.52199936 Tm [(th)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.10599995 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.60599995 74.12200165 Tm [(initiat)1(i)-1(o)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.68000031 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.18000031 74.12200165 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.02199936 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.52200317 74.12200165 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.82900238 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.32900238 74.12200165 Tm [(synthesis.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.69900513 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.19900513 74.12200165 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.0059967 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.5059967 74.12200165 Tm [(eIF)-1(-)1(3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.21099854 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.71099854 74.12200165 Tm [(complex)] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.19000244 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.69000244 74.12200165 Tm [(asso)1(c)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(iat)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.99500084 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.49500084 89.72200012 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.89099884 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.39099884 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.39199829 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.89199829 89.72200012 Tm [(40)-1(S)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.64199829 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.14199829 89.72200012 Tm [(ribo)1(some)] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.8710022 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.3710022 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.647995 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.147995 89.72200012 Tm [(fa)1(c)-1(ilitat)1(es)] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.89399719 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.39399719 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.39500427 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.89500427 89.72200012 Tm [(rec)-1(ruit)1(me)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.89900017 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.39900017 105.3219986 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.24099922 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.74099922 105.3219986 Tm [(eIF)-1(-)1(1)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.61199951 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.11199951 105.3219986 Tm [(eIF)-1(-)1(1)-1(A)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.31600189 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.81600189 105.3219986 Tm [(eIF)-1(-)1(2)-1(:)1(GTP:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.21200562 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.71200562 105.3219986 Tm [(methionyl-t)1(RNAi)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.13400269 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.63400269 105.3219986 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.91099548 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.41099548 105.3219986 Tm [(eIF)-1(-)1(5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.11599731 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.07499981 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.57499981 120.92199707 Tm [(fo)1(rm)] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.2859993 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.7859993 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.78699875 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.28699875 120.92199707 Tm [(43)-1(S)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.03700256 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.53700256 120.92199707 Tm [(preinitiat)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.9019928 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.4019928 120.92199707 Tm [(complex)] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.8809967 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.3809967 120.92199707 Tm [(\(43)-1(S)] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.13699341 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.63699341 120.92199707 Tm [(PIC\).)] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.98199463 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.48199463 120.92199707 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 238.28900146 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.78900146 120.92199707 Tm [(eIF)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(-3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.17099953 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.67099953 136.52200317 Tm [(complex)] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.15000153 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.65000153 136.52200317 Tm [(st)1(i)-1(mulat)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.53800201 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.03800201 136.52200317 Tm [(mRNA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.9960022 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.4960022 136.52200317 Tm [(rec)-1(ruit)1(me)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.72099304 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.22099304 136.52200317 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.29600525 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.79600525 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.79699707 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.29699707 136.52200317 Tm [(43)-1(S)] TJ ET EMC /P <> BDC BT 1 0 0 -1 238.04699707 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.54699707 136.52200317 Tm [(PIC)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.71899414 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.27700043 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.77700043 152.12199402 Tm [(scann)-1(ing)] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.22000122 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.72000122 152.12199402 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.56199646 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.06199646 152.12199402 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.06300354 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.56300354 152.12199402 Tm [(mRNA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.52100372 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.02099609 152.12199402 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.29899597 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.79899597 152.12199402 Tm [(AU)1(G)] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.54400635 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.04400635 152.12199402 Tm [(rec)-1(o)1(gnition.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.70199585 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.20199585 152.12199402 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.00900269 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.50900269 152.12199402 Tm [(eIF)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 167.72200012 Tm [(-3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.17099953 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.67099953 167.72200012 Tm [(complex)] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.15000153 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.65000153 167.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.21099854 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.71099854 167.72200012 Tm [(also)] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.96800232 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.46800232 167.72200012 Tm [(required)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.00900269 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.50900269 167.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.78700256 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.28700256 167.72200012 Tm [(disa)1(sse)-1(mb)1(ly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.35800171 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.85800171 167.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.13499451 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.63499451 167.72200012 Tm [(rec)-1(ycl)-1(in)] TJ ET EMC Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 172.3500061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 156.6499939 0.75 m 156.6499939 172.3500061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 172.3500061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 172.7250061 m 423.17498779 172.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm endstream endobj 6 0 obj <>stream ºÝºÝÈÈÔÚÏßÊÓÆµÃâ·Ñ <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Ö©Öë´Ê>| <Îı¾Á´> <Îı¾Á´> <Îı¾Á´> <Îı¾Á´> <Îı¾Á´> <Îı¾Á´>