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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.20001221 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm q 1 0 0 1 55 0 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 0 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 49.67599869 23.67700005 Tm 0 Tr [(EI)1(F2S1)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 114.56999969 23.67700005 Tm 2 Tr [<0005>-4<0006>-4<0007>-4<0004>-4<0008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 225.00999451 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 -55 43.75799942 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -55 61.9640007 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -2.5 61.9640007 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 8 61.9640007 Tm [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 31.625 61.9640007 Tm [(EIF)-1(2S1)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 62.31500244 61.9640007 Tm [<00050006000700040008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 114.81500244 61.9640007 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.31500244 61.9640007 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 82.6780014 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000E000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(EIF2S)-1(1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.79799652 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.17199707 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.82200623 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.19599915 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.75500488 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.1289978 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.92500305 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 116.21700287 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000B000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(eukar)1(yoti)-1(c)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.86100006 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.09100342 12.82499981 Tm [(transl)-1(ation)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.34100342 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.57099915 12.82499981 Tm [(in)-1(iti)-1(atio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.84399414 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.07400513 12.82499981 Tm [(factor)] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.46299744 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.69299316 12.82499981 Tm [(2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.01499939 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.24499512 12.82499981 Tm [(su)-1(bun)-1(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.34500122 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 274.57501221 12.82499981 Tm [(alp)-1(ha;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 300.88699341 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 304.11700439 12.82499981 Tm [(EIF)-1(2;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 324.84500122 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 328.07501221 12.82499981 Tm [(EIF)-1(-2;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 352.01800537 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 355.24798584 12.82499981 Tm [(EIF)-1(2A)1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 382.05200195 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 385.28201294 12.82499981 Tm [(EIF)-1(-2A)1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 415.29998779 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 30.49699783 Tm [(EIF)-1(-2alp)-1(ha)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.63499832 30.49699783 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 167.69500732 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001000110012000F000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 201.23399353 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0014000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(EIF)-1(2S1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.06500244 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.43900299 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 234.772995 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 268.31201172 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 301.85101318 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001E001F00200021000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.96800232 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.34199524 12.82499981 Tm [(Rat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.58999634 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 335.39001465 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0022>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0023>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0024000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 368.9289856 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0006000700120025000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 402.46798706 m 416.75 402.46798706 l 416.75 433.66799927 l -1.45000005 433.66799927 l h f* Q q 1 0 0 1 0 402.46798706 cm /P <> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 433.66799927 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 461.60699463 cm q 1 g 0.375 0.75 m 164.5249939 0.75 l 164.5249939 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 165.5249939 -0.25 l 165.5249939 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 165.2749939 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 165.2749939 156.75 l h f* Q q 1 0 0 1 164.8999939 0 cm -0.625 -0.25 m 258.5249939 -0.25 l 258.5249939 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(tr)1(anslatio)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.16799927 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.66799927 11.72200012 Tm [(initiat)1(i)-1(o)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.74199677 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.24199677 11.72200012 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.36099243 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.86099243 11.72200012 Tm [(EIF2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.51400757 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.01400757 11.72200012 Tm [(cata)1(l)-1(yzes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.68600464 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.18600464 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.18699646 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.68699646 11.72200012 Tm [(first)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.15800476 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(regulat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.43199921 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.93199921 27.3220005 Tm [(st)1(e)-1(p)] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.30599976 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.80599976 27.3220005 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.64800262 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.14800262 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.45500183 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.95500183 27.3220005 Tm [(synthesis)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.15899658 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.65899658 27.3220005 Tm [(initiat)1(i)-1(o)1(n,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.8999939 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.3999939 27.3220005 Tm [(pro)1(motin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.75699997 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.25699997 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.25799942 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.75799942 42.92200089 Tm [(binding)] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.90200043 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.40200043 42.92200089 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.2440033 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.7440033 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.74500275 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.24500275 42.92200089 Tm [(initiat)1(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.81500244 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.31500244 42.92200089 Tm [(tR)1(NA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.19299316 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.69299316 42.92200089 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.76800537 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.26800537 42.92200089 Tm [(40)-1(S)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.01800537 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.51800537 42.92200089 Tm [(ribo)1(somal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.50999451 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.00999451 42.92200089 Tm [(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ubunits.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.4659996 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.9659996 58.52199936 Tm [(Bi)-1(nd)1(i)-1(ng)] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.00800323 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.50800323 58.52199936 Tm [(occ)-1(urs)] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.40399933 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.90399933 58.52199936 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.04499817 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.54499817 58.52199936 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.51999664 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.02000427 58.52199936 Tm [(ternary)] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.63699341 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.13699341 58.52199936 Tm [(complex)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.61599731 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.11599731 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.95799255 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.45799255 58.52199936 Tm [(methi)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(onyl-tR)1(NA,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.36399841 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.86399841 74.12200165 Tm [(EIF2,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.68299866 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.18299866 74.12200165 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.45999908 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.95999908 74.12200165 Tm [(GTP.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.48500061 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.98500061 74.12200165 Tm [(EIF2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.63800049 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.13800049 74.12200165 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.69900513 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.19900513 74.12200165 Tm [(composed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.36599731 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.86599731 74.12200165 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.70799255 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.20799255 74.12200165 Tm [(3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.48599243 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.98599243 74.12200165 Tm [(noni)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(dentical)] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.04000092 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.54000092 89.72200012 Tm [(subunits,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.17199707 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.67199707 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.67299652 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.17299652 89.72200012 Tm [(36)-1(-)1(k)-1(D)] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.37799835 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.87800598 89.72200012 Tm [(EIF2-alph)1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.05799866 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.55799866 89.72200012 Tm [(subunit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.85800171 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.35800171 89.72200012 Tm [(\(EIF2S)-1(1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(\),)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.17199993 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.67199993 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.67300034 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.17300034 105.3219986 Tm [(38)-1(-)1(k)-1(D)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.37799835 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.87799835 105.3219986 Tm [(EIF2-beta)] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.60700226 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.10700226 105.3219986 Tm [(subunit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.40699768 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.90699768 105.3219986 Tm [(\(EIF2S)-1(2;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.20399475 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.70399475 105.3219986 Tm [(MIM)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.93600464 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.43600464 105.3219986 Tm [(60)-1(39)-1(08)-1(\),)] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.2749939 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.7749939 105.3219986 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(nd)] TJ ET EMC /P <> BDC BT 1 0 0 -1 11.30300045 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80300045 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.80400085 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.30400085 120.92199707 Tm [(52)-1(-)1(k)-1(D)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.50899887 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.00900269 120.92199707 Tm [(EIF2-ga)1(mma)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.12799835 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.62799835 120.92199707 Tm [(subunit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.92799377 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.42799377 120.92199707 Tm [(\(EIF2S)-1(3;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.7250061 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.2250061 120.92199707 Tm [(MIM)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.45700073 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.95700073 120.92199707 Tm [(30)-1(01)-1(6)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(1\).)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.44999981 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.94999981 136.52200317 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.75699997 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.25699997 136.52200317 Tm [(rat)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.12799835 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.62799835 136.52200317 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.47000122 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.97000122 136.52200317 Tm [(fo)1(rmatio)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.67199707 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.17199707 136.52200317 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.01399994 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.51400757 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.51499939 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.01499939 136.52200317 Tm [(ternary)] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.63200378 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.13200378 136.52200317 Tm [(complex)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.61099243 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.11099243 136.52200317 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.67199707 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.17199707 136.52200317 Tm [(mo)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(dulat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.88899994 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.38899994 152.12199402 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.90100098 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.40100098 152.12199402 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.40200043 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.90200043 152.12199402 Tm [(ph)1(osph)1(orylation)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.67599487 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.17599487 152.12199402 Tm [(st)1(ate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.1289978 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.6289978 152.12199402 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.47099304 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.97099304 152.12199402 Tm [(EIF2-alph)1(a.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.31799316 152.12199402 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 156.75 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 164.8999939 0.75 m 164.8999939 156.75 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 156.75 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 157.125 m 423.17498779 157.125 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
endstream
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