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g [<0009000A000B000C000D>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 86.625 12.82499981 Tm [(CDKAL1)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 122.57499695 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 175.07499695 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 180.32499695 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CDKA)1(L)-1(1)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 117.05899811 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 119.43299866 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 145.08299255 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 147.45700073 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 191.01600647 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 193.38999939 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 231.18600464 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CDK5)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 85.83499908 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 88.20899963 12.82499981 Tm [(re)1(gul)-1(atory)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 132.46000671 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 134.83399963 12.82499981 Tm [(su)-1(bun)-1(it)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 166.93400574 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 169.30799866 12.82499981 Tm [(asso)-1(c)1(i)-1(ate)1(d)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 214.2250061 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 216.59899902 12.82499981 Tm [(protein)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 247.98100281 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 250.35499573 12.82499981 Tm [(1)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 255.67700195 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 258.05099487 12.82499981 Tm [(li)-1(ke)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 272.86801147 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 275.24200439 12.82499981 Tm [(1)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 280.56399536 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 41 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 42 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0014000D>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CDKAL1)] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 96.32499695 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000D>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000D>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 128.3480072 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 73 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0022>] TJ ET EMC /P <</MCID 74 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0023>] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 77 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0024000D>] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 82 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700120025000D>] TJ ET EMC /P <</MCID 83 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 88 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 89 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 90 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 91 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 169.0249939 0.75 l 169.0249939 78.75 l 0.375 78.75 l h f* Q q -0.625 -0.25 m 170.0249939 -0.25 l 170.0249939 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 92 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 42.92200089 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 93 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 42.92200089 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 169.7749939 0.75 m 422.42498779 0.75 l 422.42498779 78.75 l 169.7749939 78.75 l h f* Q q 1 0 0 1 169.3999939 0 cm -0.625 -0.25 m 254.0249939 -0.25 l 254.0249939 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 94 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 175.14100647 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 179.64100647 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 215.90499878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 220.40499878 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 229.24699402 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 233.74699402 11.72200012 Tm [(th)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(e)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 5.10599995 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 9.60599995 27.3220005 Tm [(methylth)1(iotra)1(n)-1(s)1(fe)-1(r)1(ase)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 103.59600067 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 108.09600067 27.3220005 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 136.34399414 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 140.84399414 27.3220005 Tm [(The)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 156.65100098 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 161.15100098 27.3220005 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 196.89199829 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 201.39199829 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 210.23399353 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 214.73399353 27.3220005 Tm [(th)1(is)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 230.19000244 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 234.69000244 27.3220005 Tm [(ge)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ne)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 10.65200043 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 15.15200043 42.92200089 Tm [(is)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 21.71299934 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 26.21299934 42.92200089 Tm [(not)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 40.83399963 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 45.33399963 42.92200089 Tm [(kn)-1(o)1(wn.)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 76.31999969 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 80.81999969 42.92200089 Tm [(Genome-wid)1(e)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 141.68400574 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 146.18400574 42.92200089 Tm [(asso)1(c)-1(iat)1(ion)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 194.11099243 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 198.61099243 42.92200089 Tm [(st)1(u)-1(d)1(ie)-1(s)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 229.1000061 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 233.6000061 42.92200089 Tm [(ha)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ve)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 9.83100033 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 14.33100033 58.52199936 Tm [(link)-1(ed)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 40.43000031 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 44.93000031 58.52199936 Tm [(single)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 70.29499817 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 74.79499817 58.52199936 Tm [(nuc)-1(leotid)1(e)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 120.23400116 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 124.73400116 58.52199936 Tm [(po)1(l)-1(ymor)1(phisms)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 191.40299988 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 195.90299988 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 203.84399414 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 208.34399414 58.52199936 Tm [(an)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 218.86500549 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 223.36500549 58.52199936 Tm [(intro)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(n)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 5.546 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 10.04599953 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 18.88800049 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 23.38800049 74.12200165 Tm [(th)1(is)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 38.84400177 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 43.34400177 74.12200165 Tm [(gene)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 64.86000061 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 69.36000061 74.12200165 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 87.7559967 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 92.2559967 74.12200165 Tm [(susce)-1(pt)1(ibilty)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 145.90400696 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 150.40400696 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 159.47900391 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 163.97900391 74.12200165 Tm [(type)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 182.94999695 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 187.44999695 74.12200165 Tm [(2)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 192.72799683 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 197.22799683 74.12200165 Tm [(dia)1(be)-1(t)1(es.)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 236.00100708 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 78.75 cm q /GS2 gs 1 g 0.375 0.75 m 169.0249939 0.75 l 169.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 170.0249939 -0.25 l 170.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 180 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 181 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 169.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 169.7749939 16.35000038 l h f* Q q 1 0 0 1 169.3999939 0 cm -0.625 -0.25 m 254.0249939 -0.25 l 254.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 182 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ELISA,)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 25.90600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 30.40600014 11.72200012 Tm [(IHC)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 46.03300095 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 95.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 169.0249939 0.75 l 169.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 170.0249939 -0.25 l 170.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 186 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 191 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 169.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 169.7749939 16.35000038 l h f* Q q 1 0 0 1 169.3999939 0 cm -0.625 -0.25 m 254.0249939 -0.25 l 254.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 192 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CDK)1(AL1)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 34.81800079 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 111.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 169.0249939 0.75 l 169.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 170.0249939 -0.25 l 170.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 194 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 195 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 169.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 169.7749939 16.35000038 l h f* Q q 1 0 0 1 169.3999939 0 cm -0.625 -0.25 m 254.0249939 -0.25 l 254.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 196 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Ful)-1(l)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 15.11699963 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 19.61700058 11.72200012 Tm [(len)-1(g)1(th)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 47.31600189 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 51.81600189 11.72200012 Tm [(fusion)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 78.31099701 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 82.81099701 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 114.11799622 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 127.80000305 cm q /GS2 gs 1 g 0.375 0.75 m 169.0249939 0.75 l 169.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 170.0249939 -0.25 l 170.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 204 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 207 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 169.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 169.7749939 16.35000038 l h f* Q q 1 0 0 1 169.3999939 0 cm -0.625 -0.25 m 254.0249939 -0.25 l 254.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 208 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CDK)1(5)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 23.86700058 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 28.36700058 11.72200012 Tm [(regulat)1(ory)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 72.85700226 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 77.35700226 11.72200012 Tm [(subunit)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 109.65699768 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 114.15699768 11.72200012 Tm [(asso)1(c)-1(iat)1(e)-1(d)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 159.28399658 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 163.78399658 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 195.09100342 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 199.59100342 11.72200012 Tm [(1)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 204.8690033 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 209.3690033 11.72200012 Tm [(lik)-1(e)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 224.16499329 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 228.66499329 11.72200012 Tm [(1)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 233.94299316 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 144.1499939 cm q /GS2 gs 1 g 0.375 0.75 m 169.0249939 0.75 l 169.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 170.0249939 -0.25 l 170.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 224 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(P)-1(r)1(o)-1(t:)] TJ ET EMC /P <</MCID 225 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 46.56900024 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 169.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 169.7749939 16.35000038 l h f* Q q 1 0 0 1 169.3999939 0 cm -0.625 -0.25 m 254.0249939 -0.25 l 254.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 226 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q5V)-1(V42)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 35.3409996 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 160.5 cm q /GS2 gs 1 g 0.375 0.75 m 169.0249939 0.75 l 169.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 170.0249939 -0.25 l 170.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 228 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ELISA)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 25.2689991 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 29.7689991 11.72200012 Tm [(Recommend)1(e)-1(d)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 97.8010025 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 102.3010025 11.72200012 Tm [(di)1(lution:)] TJ ET EMC /P <</MCID 233 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 140.14700317 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 169.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 169.7749939 16.35000038 l h f* Q q 1 0 0 1 169.3999939 0 cm -0.625 -0.25 m 254.0249939 -0.25 l 254.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 234 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(50)-1(00)-1(-)1(1)-1(00)-1(00)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 51.39400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 176.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 169.3999939 0.75 m 169.3999939 78.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 169.3999939 79.5 m 169.3999939 95.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 169.3999939 95.84999847 m 169.3999939 111.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 169.3999939 112.19999695 m 169.3999939 127.79999542 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 169.3999939 128.54998779 m 169.3999939 144.1499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 169.3999939 144.8999939 m 169.3999939 160.5 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 169.3999939 161.25 m 169.3999939 176.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 176.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 79.125 m 422.42498779 79.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 95.47499847 m 422.42498779 95.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 111.82499695 m 422.42498779 111.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 128.17498779 m 422.42498779 128.17498779 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 144.5249939 m 422.42498779 144.5249939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 160.875 m 422.42498779 160.875 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 177.2250061 m 423.17498779 177.2250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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</body>